메뉴 건너뛰기




Volumn 15, Issue 6, 1998, Pages 863-869

Interaction of a self-emulsifying lipid drug delivery system with the everted rat intestinal mucosa as a function of droplet size and surface charge

Author keywords

Cyclosporine A; Emulsion; Everted intestine; Mucin; Peyer's patches; Positive charge; Self emulsifying

Indexed keywords

ALCOHOL; ARMEEN; CYCLOSPORIN A; OLEIC ACID; OLEIC ACID ETHYL ESTER; OLEYLAMINE; POLYSORBATE 80; UNCLASSIFIED DRUG;

EID: 0031780652     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011968313933     Document Type: Article
Times cited : (117)

References (16)
  • 1
    • 85047692219 scopus 로고
    • Novel formulation strategies for improving oral bioavailability of drugs with poor membrane permeation
    • B. J. Aungust. Novel formulation strategies for improving oral bioavailability of drugs with poor membrane permeation. J. Pharm. Sci. 82:979-987 (1993).
    • (1993) J. Pharm. Sci. , vol.82 , pp. 979-987
    • Aungust, B.J.1
  • 2
    • 0028194817 scopus 로고
    • Self-emulsifying drug delivery systems (SEDDS) with polyglycolized glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs
    • N. H. Shah, M. T. Carvajal, C. I. Patel, M. H. Infe, and A. W. Malick. Self-emulsifying drug delivery systems (SEDDS) with polyglycolized glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs. Int. J. Pharm. 106:15-23 (1994).
    • (1994) Int. J. Pharm. , vol.106 , pp. 15-23
    • Shah, N.H.1    Carvajal, M.T.2    Patel, C.I.3    Infe, M.H.4    Malick, A.W.5
  • 3
    • 0030298897 scopus 로고    scopus 로고
    • Positively charged self-emulsifying oily formulation for improving oral bioavailability of progesterone
    • T. Gershanik and S. Benita. Positively charged self-emulsifying oily formulation for improving oral bioavailability of progesterone. Pharm. Develop. Technol. 1:147-157 (1996).
    • (1996) Pharm. Develop. Technol. , vol.1 , pp. 147-157
    • Gershanik, T.1    Benita, S.2
  • 4
    • 0015444348 scopus 로고
    • Membrane potentials of epithelial cells in rat small intestine
    • R. J. Barry and J. Eggenton. Membrane potentials of epithelial cells in rat small intestine. J. Physiol. 227:201-216 (1972).
    • (1972) J. Physiol. , vol.227 , pp. 201-216
    • Barry, R.J.1    Eggenton, J.2
  • 5
    • 0015449512 scopus 로고
    • Ionic basis of membrane potentials of epithelial cells in rat small intestine
    • R. J. Barry and J. Eggenton. Ionic basis of membrane potentials of epithelial cells in rat small intestine. J. Physiol. 227:217-231 (1972).
    • (1972) J. Physiol. , vol.227 , pp. 217-231
    • Barry, R.J.1    Eggenton, J.2
  • 6
    • 0021931148 scopus 로고
    • Properties of gastric and duodenal mucus: Effect of proteolysis, disulfide reduction, bile, acid, ethanol and hypertonity on mucin gel structure
    • A. E. Bell, L. A. Sellers, A. Allen, W. J. Cunliffe, E. R. Morris, and S. B. Ross-Murphy. Properties of gastric and duodenal mucus: effect of proteolysis, disulfide reduction, bile, acid, ethanol and hypertonity on mucin gel structure. Gastroenterol. 88:269-80 (1985).
    • (1985) Gastroenterol. , vol.88 , pp. 269-280
    • Bell, A.E.1    Sellers, L.A.2    Allen, A.3    Cunliffe, W.J.4    Morris, E.R.5    Ross-Murphy, S.B.6
  • 7
    • 0024812527 scopus 로고
    • Mucus glycoprotein, its biophysical and gel-forming properties
    • A. Silberberg. Mucus glycoprotein, its biophysical and gel-forming properties. Symp. Exp. Biol. 43:43-60 (1989).
    • (1989) Symp. Exp. Biol. , vol.43 , pp. 43-60
    • Silberberg, A.1
  • 8
    • 0024832927 scopus 로고
    • Drug-mucus actions and interactions
    • C. Marriott. Drug-mucus actions and interactions. Symp. Soc. Exp. Biol. 43:163-175 (1989).
    • (1989) Symp. Soc. Exp. Biol. , vol.43 , pp. 163-175
    • Marriott, C.1
  • 9
    • 0029055473 scopus 로고
    • Comparison of the gastro-intestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals
    • T. T. Kararly. Comparison of the gastro-intestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals. Biopharm, and Drug Dispos. 16:351-380 (1995).
    • (1995) Biopharm, and Drug Dispos. , vol.16 , pp. 351-380
    • Kararly, T.T.1
  • 10
    • 0025356809 scopus 로고
    • Rapid insorption of small particles in the gut
    • W. Sass, H-P. Dreyer, and J. Seifert. Rapid insorption of small particles in the gut. Am. J. Gastroenterol. 85:255-260 (1990).
    • (1990) Am. J. Gastroenterol. , vol.85 , pp. 255-260
    • Sass, W.1    Dreyer, H.-P.2    Seifert, J.3
  • 11
    • 0028173239 scopus 로고
    • Intestinal uptake of cimetidine and ranitidine in rats
    • V. Mummaneni and J. B. Dressman. Intestinal uptake of cimetidine and ranitidine in rats. Pharm. Res. 11:1599-1604 (1994).
    • (1994) Pharm. Res. , vol.11 , pp. 1599-1604
    • Mummaneni, V.1    Dressman, J.B.2
  • 12
    • 0030467140 scopus 로고    scopus 로고
    • Bioadhesion of lectinlatex conjugates to rat intestinal mucosa
    • J. M. Irache, C. Durrer, D. Duchene, and G. Ponchel. Bioadhesion of lectinlatex conjugates to rat intestinal mucosa. Pharm. Res. 13:1716-1719 (1996).
    • (1996) Pharm. Res. , vol.13 , pp. 1716-1719
    • Irache, J.M.1    Durrer, C.2    Duchene, D.3    Ponchel, G.4
  • 13
    • 0025201837 scopus 로고
    • Estimation of Cyclosporin-A in whole blood by simple and rapid reversed-phase HPLC utilizing a salting-out extraction procedure
    • A. J. Rustum. Estimation of Cyclosporin-A in whole blood by simple and rapid reversed-phase HPLC utilizing a salting-out extraction procedure. Chromatogr. Sci. 28:594-598 (1990).
    • (1990) Chromatogr. Sci. , vol.28 , pp. 594-598
    • Rustum, A.J.1
  • 14
    • 0029969390 scopus 로고    scopus 로고
    • Diffusity of the bile salt/phospholipid aggregates in mucin
    • C-Y. Li, C. L. Zimmerman, and T. S. Weidmann. Diffusity of the bile salt/phospholipid aggregates in mucin. Pharm. Res. 4:535-541 (1996).
    • (1996) Pharm. Res. , vol.4 , pp. 535-541
    • Li, C.-Y.1    Zimmerman, C.L.2    Weidmann, T.S.3
  • 15
    • 0024848505 scopus 로고
    • Is gastro-intestinal mucus a ion selective barrier?
    • D. Guth and W. V. Engelhardt. Is gastro-intestinal mucus a ion selective barrier? Symp. Soc. Exp. Biol. 43:117-121 (1989).
    • (1989) Symp. Soc. Exp. Biol. , vol.43 , pp. 117-121
    • Guth, D.1    Engelhardt, W.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.