Experimental study on anti-neoplastic activity of epigallocatechin-3-gallate in digestive tract carcinomas

Chinese Journal of Gastroenterology

Volumn 8, Issue 6, 2003, Pages 326-331

  Ran, Zhihua ^a   Zou, Jian ^a   Feng, Ying ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cell line; Enzyme linked immunosorbent assay; Epigallocatechin 3 gallate; Gastrointestinal neoplasms; Polymerase chain reaction; Telomerase

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTINEOPLASTIC AGENT; EPIGALLOCATECHIN GALLATE; TELOMERASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL KILLING; CLINICAL PROTOCOL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; DRUG SENSITIVITY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GASTROINTESTINAL CARCINOMA; HUMAN; HUMAN CELL; IC 50; INCUBATION TIME; POLYMERASE CHAIN REACTION;

EID: 1442355289     PISSN: 10087125     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Balentine DA, Wiseman SA, Bouwens LC. The chemistry of tea flavonoids. Crit Rev Food Sci Nutr, 1997, 37: 693-704.
2. Hibasami H, Achiwa Y, Fujikawa T, Komiya T. Induction of programmed cell death (apoptosis) in human lymphoid leukemia cells by catechin compounds. Anticancer Res, 1996, 16 (4A): 1943-1946.
3. Ahmad N, Feyes DK, Nieminen AL, Agarwal R, Mukhtar H. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J Natl Cancer Inst, 1997, 89: 1881-1886.
4. Okabe S, Ochiai Y, Aida M, Park K, Kim SJ, Nomura T, Suganuma M, Fujiki H. Mechanistic aspects of green tea as a cancer preventive: effect of components on human stomach cancer cell lines. Jpn J Cancer Res, 1999, 90: 733-739.
5. Parkinson EK, Newbold RF, Keith WN. The genetic basis of human keratinocyte immortalisation in squamous cell carcinoma development: the role of telomerase reactivation. Eur J Cancer, 1997, 33: 727-734.
6. Hoos A, Hepp HH, Kaul S, Ahlert T, Bastert G, Wallwiener D. Telomerase activity correlates with tumor aggressiveness and reflects therapy effect in breast cancer. Int J Cancer, 1998, 79: 8-12.
7. Chung FL, Wang M, Rivenson A, Iatropoulos MJ, Reinhardt JC, Pittman B, Ho CT, Amin SG. Inhibition of lung carcinogenesis by black tea in Fischer rats treated with a tobacco-specific carcinogen: caffeine as an important constituent. Cancer Res, 1998, 58: 4096-4101.
8. Katiyar SK, Mukhtar H. Tea in chemoprevention of cancer: epidemiologic and experimental studies. Int J Oncol, 1996, 8: 221-238.
9. Yang GY, Liao J, Kim K, Yurkow EJ, Yang CS. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols. Carcinogenesis, 1998, 19: 611-616.
10. Xu Y, Ho CT, Amin SG, Han C, Chung FL. Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis in A/J mice by green tea and its major polyphenol as antioxidants. Cancer Res, 1992, 52: 3875-3879.
11. Yamane T, Takahashi T, Kuwata K, Oya K, Inagake M, Kitao Y, Suganuma M, Fujiki H. Inhibition of N-methyl-N′-nitro-N-nitrosoguanidine-induced carcinogenesis by (-)-epigallocatechin gallate in the rat glandular stomach. Cancer Res, 1995, 55: 2081-2084.
12. Pianetti S, Guo S, Kavanagh KT, Sonenshein GE. Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells. Cancer Res, 2002, 62: 652-655.
13. Wiseman SA, Balentine DA, Frei B. Antioxidants in tea. Crit Rev Food Sci Nutr, 1997, 37: 705-718.
14. Hibasami H, Komiya T, Achiwa Y, Ohnishi K, Kojima T, Nakanishi K, Akashi K, Hara Y. Induction of apoptosis in human stomach cancer cells by green tea catechins. Oncol Rep, 1998, 5: 527-529.
15. Okabe S, Suganuma M, Hayashi M, Sueoka E, Komori A, Fujiki H. Mechanisms of growth inhibition of human lung cancer cell line, PC-9, by tea polyphenols. Jpn J Cancer Res, 1997, 88: 639-643.
16. Lin YL, Lin JK. (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB. Mol Pharmacol, 1997, 52: 465-472.
17. Huang MT, Ho CT, Wang ZY, Ferraro T, Finnegan-Olive T, Lou YR, Mitchell JM, Laskin JD, Newmark H, Yang CS, Conney AH. Inhibitory effect of topical application of a green tea polyphenol fraction on tumor initiation and promotion in mouse skin. Carcinogenesis, 1992, 13: 947-954.
18. Yoshizawa S, Horiuchi T, Sugimura M, Nishiwaki S, Yatsunami J, Okabe S, Okuda T, Muto Y, Frenkel K, Troll W, Fujiki H. Penta-O-galloyl-β-D-glucose, and (-)-epigallocatechin gallate: cancer prevention agents. In: Huang MT, Ho CT, Lee CY, eds. Phenolic compounds in foods and health II: Antioxidants and cancer prevention. American Chemical Society. Washington, DC 1992. 316-325.
19. Katiyar SK, Agarwal R, Wood GS, Mukhtar H. Inhibition of 12-O-tetradecanoylphorbol-13-acetate-caused tumor promotion in 7,12-dimethylbenzanthracene-initiated SENCAR mouse skin by a polyphenolic fraction isolated from green tea. Cancer Res, 1992, 52: 6890-6897.
20. Dong Z, Ma W, Huang C, Yang CS. Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins. Cancer Res, 1997, 57: 4414-4419.
21. Cao Y, Cao R. Angiogenesis inhibited by drinking tea. Nature, 1999, 398: 381.
22. Kuo PL, Lin CC. Green tea constituent (-)-epigallocatechin-3-gallate inhibits Hep G2 cell proliferation and induces apoptosis through p53-dependent and Fas-mediated pathways. J Biomed Sci, 2003, 10: 219-227.
23. Gupta S, Hussain T, Mukhtar H. Molecular pathway for (-)-epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells. Arch Biochem Biophys, 2003, 410: 177-185.
24. Tan X, Zhou D, Zhang Y, Jiang B. Effects of different catechins on cell cycle arrest and induction of apoptosis in LoVo cells. Zhonghua Yu Fang Yi Xue Za Zhi, 2000, 34: 333-335.
25. Ahmad N, Cheng P, Mukhtar H. Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate. Biochem Biophys Res Commun, 2000, 275: 328-334.
26. Liang YC, Lin-Shiau SY, Chen CF, Lin JK. Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate. J Cell Biochem, 1999, 75: 1-12.
27. Deguchi H, Fujii T, Nakagawa S, Koga T, Shirouzu K. Analysis of cell growth inhibitory effects of catechin through MAPK in human breast cancer cell line T47D. Int J Oncol, 2002, 21: 1301-1305.
28. Okabe S, Suganuma M, Hayashi M, Sueoka E, Komori A, Fujiki H. Mechanisms of growth inhibition of human lung cancer cell line, PC-9, by tea polyphenols. Jpn J Cancer Res, 1997, 88: 639-643.
29. Xu F, Zhen YS. (-)-Epigallocatechin-3-gallate enhances anti-tumor effect of cytosine arabinoside on HL-60 cells. Acta Pharmacol Sin, 2003, 24: 163-168.
30. Horikawa I, Cable PL, Afshari C, Barrett JC. Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene. Cancer Res, 1999, 59: 826-830.
31. Takakura M, Kyo S, Kanaya T, Hirano H, Takeda J, Yutsudo M, Inoue M. Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res, 1999, 59: 551-557.
32. Autexier C, Greider CW. Telomerase and cancer: revisiting the telomere hypothesis. Trends Biochem Sci, 1996, 21: 387-391.