The molecular basis of infectious diseases: Pathogenicity islands and other mobile genetic elements - A review

Acta Microbiologica et Immunologica Hungarica

Volumn 50, Issue 4, 2003, Pages 321-330

  Hacker, J ^a   Blum Oehler, Gabriele ^a   Hochhut, Bianca ^a   Dobrindt, U ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Evolution; Flexible gene pool; Genomic islands; Pathogenicity islands

Indexed keywords

MEMBRANE PROTEIN; VIRULENCE FACTOR;

BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIOPHAGE; BACTERIUM ISOLATE; BACTERIUM ISOLATION; DNA RECOMBINATION; ESCHERICHIA COLI; GENE FUNCTION; GENE IDENTIFICATION; GENE POOL; GENE TRANSFER; GENOMIC ISLAND; INFECTION; MICROORGANISM; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY ISLAND; PLASMID; PROTEIN FUNCTION; REVIEW; TRANSPOSON; ANIMAL; BACTERIAL INFECTION; BACTERIUM; ENTEROBACTER INFECTION; EVOLUTION; GENETICS; GENOMIC INSTABILITY; HUMAN; MICROBIOLOGY; PATHOGENICITY; URINARY TRACT INFECTION; VIRULENCE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; TRANSPOSONS; UNIDENTIFIED BACTERIOPHAGE;

ANIMALS; BACTERIA; BACTERIAL INFECTIONS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; EVOLUTION; GENOME, BACTERIAL; GENOMIC INSTABILITY; GENOMIC ISLANDS; HUMANS; URINARY TRACT INFECTIONS; VIRULENCE;

EID: 1442354082     PISSN: 12178950     EISSN: None     Source Type: Journal    
DOI: 10.1556/AMicr.50.2003.4.1     Document Type: Review

References (29)

1. Ochman, H., Lawrence, J. G., Groisman, E. A.: Lateral gene transfer and the nature of bacterial innovation. Nature 405, 299-304 (2000).
2. Salyers, A. A., Shoemaker, N. B., Stevens, A. M., Li, L.-Y.: Conjugative transposons: an unusual and diverse set of integrated gene transfer elements. Microbiol Rev 59, 579-590 (1995).
3. Hacker, J., Bender, L., Ott, M., Wingender, J., Lund, B., Marre, R., Goebel, W.: Deletions of chromosomal regions coding for fimbriae and hemolysins occur in vitro and in vivo in various extraintestinal Escherichia coli isolates. Microb Pathog 8, 213-225 (1990).
4. Hacker, J. Kaper, J. B.: Pathogenicity islands and the evolution of microbes. Annu Rev Microbiol 54, 641-679 (2000).
5. Hacker, J., Carniel, E.: Ecological fitness, genomic islands and bacterial pathogenicity. EMBO Rep 2, 376-381 (2001).
6. Blum, G., Ott, M., Lischewski, A., Ritter, A., Imrich, H., Tschäpe, H., Hacker, J.: Excision of large DNA regions termed pathogenicity islands from tRNA-specific loci in the chromosome of an Escherichia coli wild-type pathogen. Infect Immun 62, 606-614 (1994).
7. Tóth, I., Oswald, E., Szabó, B., Bares, I., Emody, L.: Virulence markers of human uropathogenic Escherichia coli strains isolated in Hungary. In: Emody, L., Pál, T., Hacker, J., Blum-Oehler, G. (eds): Genes and proteins underlying microbial urinary tract virulence: basic aspects and application. Adv Exp Med Biol 485, 335-338 (2000).
8. Tóth, I., Oswald, E., Mainil, J. G., Awad-Masalmeh, M., Nagy, B.: Characterization of intestinal cnf1+ Escherichia coli from weaned pigs. Int J Med Microbiol 290, 539-542 (2000).
9. Hacker, J., Blum-Oehler, G., Janke, B., Nagy, G., Goebel, W.: Pathogenicity islands of extraintestinal Escherichia coli. In: Kaper, J., Hacker, J. (eds): Pathogenicity islands and other mobile virulence elements. ASM, Washington, 59-76 (1999).
10. 536) of uropathogenic Escherichia coli strain 536. Infect Immun 70, 6365-6372 (2002).
11. Carniel, E., Guilvout, I., Prentice, M.: Characterization of a large chromosomal "high-pathogenicity island" in biotype 1B Yersinia enterocolitica. J Bacteriol 178, 6743-6751 (1996).
12. 536. J Infect Dis 183, S17-20 (2001).
13. Hacker, J., Kaper, J. B. (eds): Pathogenicity islands and the evolution of pathogenic microbes. Springer, Berlin-Heidelberg-New York, Vol. 264 (2002).
14. Elliott, S. J., Wainwright, L.A., McDaniel, T. K., Jarvis, K. G., Deng, Y. K., Lai, L. C., McNamara, B. P., Donnenberg, M. S., Kaper, J. B.: The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69. Mol Microbiol 28, 1-4 (1998).
15. Karaolis, D. K. R., Johnson, J. A., Bailey, C. C., Boedeker, E. C., Kaper, J. B., Reeves, P. R.: A Vibrio cholerae pathogenicity island associated with epidemic and pandemic strains. Proc Natl Acad Sci USA 95, 3134-3139 (1998).
16. Mills, D. M., Bajaj, V. Lee, C. A.: A 40 kb chromosomal fragment encoding Salmonella typhimurium invasion genes is absent from the corresponding region of the Escherichia coli K-12 chromosome. Mol Microbiol 15, 749-759 (1995).
17. Hensel, M., Nikolaus, T., Egelseer, C.: Molecular and functional analysis indicates a mosaic structure of Salmonella pathogenicity island 2. Mol Microbiol 31, 489-498 (1999).
18. Kim, J. F., Alfano, J. R.: Pathogenicity islands and virulence plasmids of bacterial plant pathogens. Curr Top Microbiol Immunol 264/II, 127-147 (2002).
19. Christie, P. J., Vogel, J. P.: Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells. Trends Microbiol 8, 354-360 (2000).
20. Dobrindt, U., Hacker, J.: Plasmids, phages and pathogenicity islands: lessons on the evolution of bacterial toxins. In: Alouf, J., Freer, J. (eds): The comprehensive sourcebook of bacterial protein toxins. Academic Press, New York, 3-23 (1999).
21. Shankar, N., Baghdayan, A. S., Gilmore, M. S.: Modulation of virulence within a pathogenicity island in vancomycin-resistant Enterococcus faecalis. Nature 417, 746-750 (2002).
22. Lindsay, J. A., Ruzin, A., Ross, H. F., Kurepina, N., Novick, R. P.: The gene for toxic shock toxin is carried by a family of mobile pathogenicity islands in Staphylococus aureus. Mol Microbiol 29, 527-543 (1998).
23. Rajakumar, K., Sasakawa, C., Adler, B.: Use of a novel approach, termed island probing, identifies the Shigella flexneri she pathogenicity island which encodes a homolog of the immunoglobulin A protease-like family of proteins. Infect Immun 65, 4606-4614 (1997).
24. Cieslewicz, M., Vimr, E.: Reduced polysialic acid capsule expression in Escherichia coli K1 mutants with chromosomal defects in kpsF. Mol Microbiol 26, 237-249 (1997).
25. Schubert, S., Rakin, A., Karch, H., Carniel, E., Heesemann, J.: Prevalence of the "high-pathogenicity island" of Yersinia species among Escherichia coli strains that are pathogenic to humans. Infect Immun 66, 480-485 (1998).
26. Ölschläger, T. A., Zhang, D., Schubert, S., Carniel, E., Rabsch, W., Karch, H., Hacker, J.: The high pathogenicity island is absent in human pathogens of Salmonella enterica subspecies I but present in isolates of subspecies III and VI. J Bacteriol 185, 1107-1111 (2003).
27. Moss, J. E., Cardozo, T. J., Zychlinsky, A., Groisman, E. A.: The selC-associated SHI-2 pathogenicity island of Shigella flexneri. Mol Microbiol 33, 74-83 (1999).
28. Vokes, S. A., Reeves, S. A., Torres, A. G., Payne, S. M.: The aerobactin iron transport system genes in Shigella flexneri are present within a pathogenictiy island. Mol Microbiol 33, 63-73 (1999).
29. Morschhäuser, J., Vetter, V., Emody, L., Hacker, J.: Adhesin regulatory genes within large, unstable DNA regions of pathogenic Escherichia coli: cross-talk between different adhesin gene clusters. Mol Microbiol 11, 555-566 (1994).