Controlling influenza by inhibiting the virus's neuraminidase

Current Drug Targets

Volumn 5, Issue 2, 2004, Pages 119-136

  Garman, Elspeth ^a   Laver, Graeme ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NONE   (Australia)

Author keywords

Haemagglutinin; Influenza; Inhibitors; Ion channels; Neuraminidase; Pandemic; Relenza; Sialic acid; Tamiflu

Indexed keywords

4 ACETAMIDO 5 AMINO 3 (1 ETHYLPROPOXY) 1 CYCLOHEXENE 1 CARBOXYLIC ACID; 4 AMINO 2 DEOXY 2,3 DEHYDRO N ACETYLNEURAMINIC ACID; 5 (1 ACETYLAMINO 2 METHOXY 2 METHYLPENTYL) 4 PROPENYLPYRROLIDINE 2 CARBOXYLIC ACID; A 315675; AMANTADINE; ANTIVIRUS AGENT; GLYCOSIDASE INHIBITOR; INFLUENZA VACCINE; ION CHANNEL; N ACETYL 2,3 DIDEHYDRO 2 DEOXYNEURAMINIC ACID; N ACETYLNEURAMINIC ACID; N ACETYLNEURAMINIC ACID DERIVATIVE; OSELTAMIVIR; PERAMIVIR; PIPERIDINE DERIVATIVE; PROTEINASE INHIBITOR; RIMANTADINE; SIALIC ACID DERIVATIVE; SIALIDASE INHIBITOR; TERT BUTYLHYDROQUINONE; UNCLASSIFIED DRUG; VIRUS ENZYME; VIRUS PROTEIN; VIRUS SIALIDASE; ZANAMIVIR;

AMINO ACID SEQUENCE; ANTIVIRAL ACTIVITY; CLINICAL TRIAL; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG APPROVAL; DRUG BINDING SITE; DRUG DESIGN; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; FLU LIKE SYNDROME; HEMAGGLUTINATION; HUMAN; INFECTION CONTROL; INFLUENZA; INFLUENZA VIRUS A; NONHUMAN; PROTEIN DEGRADATION; PROTEINASE INHIBITION; REVIEW; SIDE EFFECT; STRUCTURE ACTIVITY RELATION; VIRUS IMMUNITY; VIRUS INHIBITION; VIRUS MORPHOLOGY; VIRUS MUTANT; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS RESISTANCE; VIRUS STRAIN; VIRUS TRANSCRIPTION;

ANIMALS; ANTIVIRAL AGENTS; DRUG DESIGN; ENZYME ACTIVATION; ENZYME INHIBITORS; HEMAGGLUTININS; HUMANS; INFLUENZA, HUMAN; ION CHANNELS; NEURAMINIDASE; ORTHOMYXOVIRIDAE; VIRAL FUSION PROTEINS; VIRUS REPLICATION;

EID: 1442351171     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389450043490604     Document Type: Review

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