Effect of diclofenac alone or in combination with alpha-tocopherol on the oxidative activity of polymorphonuclear leukocytes in healthy and osteoarthritic individuals

Saudi Medical Journal

Volumn 25, Issue 2, 2004, Pages 198-203

  Al Arfaj, Abdurhman S ^a,d   Alballa, Suliman R ^a   Mustafa, Ali A ^b   Al Tuwaijri, Ali S ^a   Al Humayyd, M S ^b   Al Dalaan, Abdullah N ^c  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

^c KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^d NONE   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; DICLOFENAC; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PHORBOL 13 ACETATE 12 MYRISTATE; ZYMOSAN;

ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; CELL ISOLATION; CHEMOLUMINESCENCE; CLINICAL ARTICLE; CLINICAL OBSERVATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; MEDICAL SCHOOL; NEUTROPHIL; OPSONIZATION; OSTEOARTHRITIS; SAUDI ARABIA;

ALPHA-TOCOPHEROL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; CHEMILUMINESCENT MEASUREMENTS; DICLOFENAC; DRUG THERAPY, COMBINATION; HUMANS; NEUTROPHILS; OSTEOARTHRITIS; REACTIVE OXYGEN SPECIES;

EID: 1442302376     PISSN: 03795284     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Verhoef J. The phagocytic process and the role of complement in host defense. J Chemother 1991; Suppl 1: 93-97.
2. Knight JA. Free radicals, antioxidants and the immune system. Ann Clin Lab Sci 2000; 30: 145-158.
3. Abramson S. Therapy with and mechanisms of non-steroidal anti-inflammatory drugs. Curr Opin Rheumatol 1991; 3: 336-340.
4. Altman RD. Neutrophil activation: An alteration to prostaglandin inhibition as the mechanism of action for NSAIDs. Semin Arthritis Rheum 1990; 19: 1-5.
5. Abramson SB. Mechanisms of action of nonsteroidal anti-inflammatory drugs and therapeutic considerations. Bull Hosp Jt Dis Orthop Inst 1990; 50: 107-115.
6. Abdullah AS, Jawad AM, Al-Hashimi AH. In vitro effect of different non-steroidal anti-inflammatory drugs on human polymorphonuclear leukocyte activity measured by luminol-dependent chemiluminescence of the whole blood. Saudi Med J 2001; 22: 360-365.
7. Tahamont MV, Gee MH. The effects of cyclooxygenase inhibition on chemiluminescence and aggregation in sheep neutrophils. Prostaglandins Leukot Med 1986; 24: 139-149.
8. Olinescu R, Radu D, Pintea G, Militaru M. Evaluation of the therapeutic efficiency of voltaren by using the in vitro chemiluminescence emitted by leukocytes polymorphonuclear. Rom J Intern Med 1991; 29: 199-204.
9. Asplund K. Anti-oxidant vitamins in the prevention of cardiovascular disease: a systematic review. J Intern Med 2000; 251: 372-392.
10. Burton GW, Ingold KU. Vitamin E as an in-vitro and in-vivo antioxidant. Ann N Y Acad Sci 1989; 570: 7-22.
11. Esterbauer H, Striegl G, Puhl H, Rotheneder M. The role of vitamin E and carotenoids in preventing oxidation of low density lipoproteins. Ann N Y Acad Sci 1989; 570:254-267.
12. Bieri JG, Corach L, Hubbard VS. Medical uses of vitamin E. N Engl J Med 1983; 18: 1063-1070.
13. Hodis HN, Mack WJ, La Bree L, Cashin-Hemphill L, Sevanian A, Johnson R, Azen SP. Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary artery atherosclerosis. JAMA 1995; 273: 1849-1854.
14. Bendich A, Malik R, Leader S. Potential health economic benefits of vitamin supplementation. West J Med 1997; 166: 306-312.
15. Tomeo CA, Geller M, Watkins TR, Gapor A, Bierenbaum ML. Antioxidant effects of tocotrienols in patients with hyperlipidemia and carotid stenosis. Lipids 1995; 12: 1179-1183.
16. Siegmeth W, Sieberer W. A comparison of the short-term effects of ibuprofen and diclofenac in spondylosis. J Int Med Res 1978; 6: 369-374.
17. Brooks PM, Hill W, Geddes R. Diclofenac and ibuprofen in rheumatoid arthritis and osteoarthritis. Med J Aust 1980; 1: 29-30.
18. Siraux P. Diclofenac (Voltaren) for the treatment of osteoarthrosis: a double-blind comparison with naproxen. J Int Med Res 1977; 5: 169-174.
19. Small RE. Drug Reviews: Diclofenac Sodium. Clin Pharm 1989; 8: 545-558.
20. Todd PA, Sorkin EM. Diclofenac sodium: a reappraisal of its pharmaco-dynamic and pharmacokinetics properties, and therapeutic efficacy. Drugs 1988; 35: 244-285.
21. Skoutakis VA, Carter CA, Mickle TR, Smith VH, Arkin CR, Alissandratos J et al. Review of diclofenac and evaluation of its place in therapy as a non-steroidal anti-inflammatory agent. Drug Intell Clin Pharm 1988; 22: 850-859.
22. Friman C, Johnston C, Chew C, Davis P. Effect of diclofenac sodium, tolfenamic acid and indomethacin on the production of superoxide induced by N-formyl-methionyl-leucyl-phenylalanine in normal human polymorphonuclear leukocytes. Scand J Rheumatol 1986; 15: 41-46.
23. Tono-Oka T, Ueno N, Matsumoto T, Ohkawa M, Matsumoto S. Chemiluminescence of whole blood: A simple and rapid method for the estimation of phagocytic function of granulocytes and opsonic activity in whole blood. Clin Immunol Immunopathol 1983; 26: 66-75.
24. Al-Tuwaijri AS, Al-Mofleh IA, Mahmoud AA. Effect of leishmania major on human polymorphonuclear leukocytes function in vitro. J Med Microbiol 1990; 32; 189-193.
25. Mustafa AA. Effect of venom from Cerastes Cerastes (Egyptian sand viper) on luminol-dependent chemiluminescence of human blood phagocytes cells. Immunopharmacology 1990; 20: 115-123.
26. Al-Tuwaijri AS, Mustafa AA. Verapamil enhances the inhibitory effect of diclofenac on the chemiluminescence of human polymorphonuclear leukocytes and Carageenan-induced rat's paw oedema. Int J Immunopharmacol 1992; 14: 83-91.
27. Mustafa AA, Alballa SR, Al-Tuwaijri AS, Al-Dalaan AN. Calcium channel blockers enhance the inhibitory action of non-steroidal anti-inflammatory drugs on the luminol-dependent chemiluminescence: Differential effects of tenoxicam. Saudi Med J 1993; 14: 340-346.
28. Gavioli R, Spisani S, Cavalletti T, Marangoni C, Traniello S. Indomethacin and oxamethacin as modulators of the production of superoxide anion in human leukocytes. Boll Soc Ital Biol Sper 1984; 60: 1095-1101.
29. Wildfeuer A. Effects of non-steroidal anti-inflammatory drugs on human leukocytes. Z Rheumatol 1983; 42: 16-20.
30. Horan TD, Noujaim AA, McPherson TA. Effect of indomethacin on human neutrophil chemiluminescence and microbicidal activity. Immunopharmacology 1983; 6: 97-106.
31. Berradia N, Marchand-Arvier M, Humbert JC, Vigneron C. Effects of indomethacin and diclofenac on some functions of polymorphonuclear neutrophils. J Pharm Pharmacol 1988; 40: 806-808.
32. Perianin A, Giroud JP, Hakim J. Nonsteroidal anti-inflammatory drugs as tools for analysis of neutrophil functions. Biomed Pharmacother 1987; 41: 315-321.
33. Moreno-Sanchez R, Bravo C, Vasquez C, Ayala G, Silveira LH, Martinez-Lavin M. Inhibition and uncoupling of oxidative phosphorylation by non-steroidal anti-inflammatory drugs: study in mithochondria, submithochondrial particles, cells and whole heart. Biochem Pharmacol 1999; 57: 743-752.
34. Lomas DA, Shaw J, Burnett D, Stockley RA. Effect of non-steroidal anti-inflammatory drugs on neutrophil chemotaxis on in vitro and in vivo study. Br J Rheumatol 1990; 29: 363-367.
35. Henricks PA, Van der Tol ME, Van Kats Renaud JH, Nijkamp FP, Verhoef J. Differences in the effect of arachidonic acid on polymorphonuclear and mononuclear leukocyte function. Biochim Biophys Acta 1984; 801: 206-214.
36. Tissot M, Roch-Arveiller M, Fontagne J, Giroud JP. Effects of niflumic acid on polyphoinositide and oxidative metabolis in polymorphonuclear leukocytes from healthy and thermally injured rats. Inflammation 1992; 16: 645-657.
37. Tang XL, McCay PB, Sun JZ, Hartley CJ, Schleman M, Bolli R. Inhibitory effect of a hydrophilic alpha-tocopherol analogue: MDL 75,405, on generation of free radicals in stunned myocardium in dogs. Free Radic Res 1995; 22: 293-302.
38. Jakus J, Kriska T, Vanyur R. Effect of multivitamins in an effervescent preparation on the respiratory burst of peritoneal macrophages in mice. Br J Nutr 2002; 87: 501-508.
39. Bowry VW, Ingold KU, Stocker R. Vitamin E in human low-density lipoprotein: when and how this antioxidant becomes a pro-oxidant. Biochem J 1992, 288: 341-344.