In vitro effect of different non-steroidal anti-inflammatory drugs on human polymorphonuclear leukocyte activity measured by luminol-dependent chemiluminescence of the whole blood

Saudi Medical Journal

Volumn 22, Issue 4, 2001, Pages 360-365

  Abdullah, Asia S ^a   Jawad, Abdullah M ^a   Al Hashimi, Ali H ^a  

^a UNIVERSITY OF BASRAH   (Iraq)

Author keywords

Aspirin; Chemiluminescence; Diclofenac; Ibuprofen; Indomethacin; Non steroidal anti inflammatory drugs; Polymorphonuclear leukocyte activity

Indexed keywords

ACETYLSALICYLIC ACID; BARIUM SULFATE; DICLOFENAC; IBUPROFEN; INDOMETACIN; LUMINOL; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; ARTICLE; CHEMOLUMINESCENCE; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MALE; NEUTROPHIL; NORMAL HUMAN;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; BARIUM SULFATE; BLOOD GROUP ANTIGENS; CHEMILUMINESCENT MEASUREMENTS; CONTRAST MEDIA; DICLOFENAC; DRUG EVALUATION, PRECLINICAL; ERYTHROCYTE INDICES; FEMALE; HEMOGLOBINS; HUMANS; IBUPROFEN; INDICATORS AND REAGENTS; INDOMETHACIN; LEUKOCYTE COUNT; LUMINOL; MALE; MIDDLE AGED; NEUTROPHILS;

EID: 0035028945     PISSN: 03795284     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. BeDell LS, editor-in-chief. Physicians Gen Rx. the complete drug reference. Missouri (USA): Mosby; 1996, p. 143, 1120, 1139, 1711.
2. British National formulary (BNF). A joint publication of the British Medical Association and the Royal Pharmaceutical Society of Great Britain: London (UK); 1998. No. 36.
3. Walker JS, Nguyen TV, Day RO. Clinical response to NSAIDs in urate-crystal induced inflammation: a simultaneous study of intersubject and intrasubject variability. Br J Clin Pharmacol 1994; 38: 341-347.
4. Scheiman, MD. NSAIDs, Gastrointestinal injury, and cytoprotection. Gastroenterol Clin North Am 1996; 25: 279-298.
5. Cashman J, McAnulty G. NSAIDs in perisurgical pain management. Mechanisms of action and rationale for optimum use. Drugs 1995; 49: 51-70.
6. Vesell ES, Penno MB. Assessment methods to identify sources of interindividual pharmacokinetic variations. Clin Pharmacokinet 1983; 8: 378-409.
7. Pairet M, Engelhardt G. Distinct isoforms (COX-1 and COX-2) of cycloxygenase: possible physiological and therapeutic implications. Fundamen Clin Pharmacol 1996; 10: 1-15.
8. Dubois RA, Eberhart CE, Williams CS. Introduction to eicosanoids and the Gastroenteric tract. Gastroenterol Clin North Am 1996; 25: 267-277.
9. Dubois N, Muller N, Lapicque F, Gillet P, Netter P, Royer RJ. Stereoselective protein binding of NSAIDs: Pharmacological implications. Therapie 1993; 48: 325-329.
10. Rudy AC, Bradley JD, Ryan SI, Kalasinski LA, Xiaotao Q, Hall SD. Variability in the dispostion of Ibuprofen enantiomers in osteoarthritic patients. Ther Drug Monit 1992; 14: 464-470.
11. Hundal Q. Studies on the possible relationship between levels of piroxicam and naproxen in biological fluids from patients with osteoarthritis as well as reactive arthritis and clinical events [doctoral thesis]. Oslo (Norway): The National Hospital; 1994.
12. Berradia N, Marchand-Arvier M, Humbert JC, Vigneron C. Effects of indomethacin and diclofanac on some functions of polymorphonuclear neutrophils. J Pharm Pharmacol 1988; 40: 806-808.
13. Smolen JE, Weissmann G. Effects of Indomethacin, 5, 8, 11, 14. Eicosatctraynoic acid (Etya) and P-Bromophenacylbromide (BPB) on Lysosomal enzyme release and superoxide anion generation by human polymorphonuclear leukocytes. Biochem Pharmacol 1980; 29: 533-538.
14. Bodaness RS, Chan PC. Reaction of indomethacin with singlet molecular oxygen. Biochem Pharmacol 1980; 29: 1337-1340.
15. Gay JC, Lukens JN, English DK. Differential inhibition of Neutrophil superoxide generation by NSAIDs. Inflammation 1984; 8: 209-222.
16. Dale MM, Penfield A. Superoxide generation by either 1-olcoyl-2-acetylglycerol or A23187 in human neutrophils is enhanced by indomethacin. FEBS Letts 1985; 185: 213-217.
17. Rao BA, Sisodia P, Janardhan A, Sattur BP. Inhibition of superoxide anion production from activated phagocytes by anti-inflammatory drugs. Indian J Exp Biol 1986; 24: 644-646.
18. Friman C, Johnston C, Chew C, Davis P. Effect of diclofenac sodium, tolfenamic acid and indomethacin on the production of superoxide induced by N-formyl-Methionyl Leucyl-Phenylalanine in normal human PMNs. Scand J Rheumatol 1986; 15: 41-46.
19. Neal TM, Vissers MCM, Winterbourn CC. Inhibition by nonsteroidal antiinflammatory drugs of superoxide production and Granule enzyme release by polymorphonuclear leukocytes stimulated with immune complexes or formyl-methionyl-leucyl-phenylalanine. Biochem Pharmacol 1987; 36: 2511-2517.
20. Mustafa AA, Ali-Balia SR, Al-Tawaijri AS, Al-Dalaan A. Calcium channel blockers enhance the inhibitory action of non-steroidal anti-inflammatory drugs on the luminol dependent chemiluminescence: differential effects of Tenoxicam. Saudi Med J 1993; 14: 340-346.
21. Minakami K, Watanabe Y, Miyahara M, Kobaachi H, Kurashige T, Utsumi K. Effects of indomethacin and aspirin on the TNF-alpha-induced priming and protein tyrosyl phosphorylation of human neutrophils. Physiol Chem Phys Med NMR 1993; 25: 55-67.
22. Arthur L, Sagone, Jr. Effect of anti-inflammatory agents on the hydroxyl radical (OH) producing of zymosan stimulated human granulocytes (PMNs). Oxygen and Oxy-Radicals in Chem Biol 1981; 719-724.
23. Vladimirov YUA, Sherstnev MP, Piryazev AP. Chemiluminescence of the leukocytes of whole blood stimulated by barium sulphate crystals. Biophysics 1989; 34: 1136-1140.
24. Daci JV, Lewis SM. Practical Hematology. 6th ed. Edinburgh: Churchill Livingstone: 1984.
25. Rugstad HE, Hundal O, Holme I, Herland OBV, Husby G, Giercksky KE. Piroxicam and naproxen plasma concentration in patients with osteoarthritis: relation to age, sex, efficacy and adverse events. Clin Rheumatol 1986; 5: 389-398.
26. Halliwell B. Reactive oxygen species in living systems: source, biochemistry, and role in human disease. Am J Med 1991;91 (Suppl 3c): 145-225.
27. Sakumoto M, Matsumoto T, Mochida O, Kubo S, Mizunoe Y, Kumazawa J. Chemiluminescence response of whole blood in patients undergoing urological operations. Int Urol Nephrol 1997; 29: 473-478.
28. Brown GE, Reiff J, Allen RC, Silver GM, Fink MP. Maintenance and down-regulation of primed neutrophil chemiluminescence activity in human whole blood. J Leukoc Biol 1997; 62: 837-844.
29. Jawad AM, Rogers HJ. The effects of flurbiprofen and indomethacin on the mitogenic response of human peripheral mononuclear cells. Immunopharmacology 1984; 7: 59-67.
30. Biemond P, Swaak AJG, Penders JMA, Eindoff CMB, Koster JF. Superoxide production by polymorphonuclear leucocytes in rheumatoid arithritis and osteoarthritis: in vivo inhibition by the antirheumatic drug piroxicam due to interference with the activation of the NADPH-Oxidase. Ann Rheum Dis 1986; 45: 249-255.