Stimulus and cell-type-specific release of purines in cultured rat forebrain astrocytes and neurons

Journal of Neurochemistry

Volumn 88, Issue 5, 2004, Pages 1305-1312

  Parkinson, Fiona E ^a   Xiong, Wei ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Adenosine 5 monophosphate deaminase; Adenosine deaminase; Inosine 5 monophosphate; Nucleoside release; Nucleoside transport

Indexed keywords

9 (2 HYDROXY 3 NONYL)ADENINE; ADENOSINE; ADENOSINE DEAMINASE; ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE DIPHOSPHATE; DEOXYGLUCOSE; DIPYRIDAMOLE; ECTO 5' NUCLEOTIDASE; GLUCOSE; INOSINE; NUCLEOSIDE TRANSPORTER; PURINE;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN ISCHEMIA; BRAIN METABOLISM; CELL SECRETION; CELL STIMULATION; FOREBRAIN; HYDROLYSIS; HYPOGLYCEMIA; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ADENINE; ADENOSINE; ADENOSINE TRIPHOSPHATE; ANIMALS; ASTROCYTES; CELL HYPOXIA; CELLS, CULTURED; DEOXYGLUCOSE; GLUCOSE; INOSINE; IODOACETIC ACID; NEURONS; OLIGOMYCINS; PROSENCEPHALON; PURINES; RATS; STIMULATION, CHEMICAL;

ANIMALIA;

EID: 1442299419     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02266.x     Document Type: Article

References (30)

1. Andiné P., Rudolphi K. A., Fredholm B. B. and Hagberg H. (1990) Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia. Br. J. Pharmacol. 100, 814-818.
2. Brosh S., Sperling O., Bromberg Y. and Sidi Y. (1990) Developmental changes in the activity of enzymes of purine metabolism in rat neuronal cells in culture and in whole brain. J. Neurochem. 54, 1776-1781.
3. Castellano B., Gonzale Z. B., Finsen B. R. and Zimmer J. (1990) Histochemical demonstration of purine nucleoside phosphorylase (PNPase) in microglial and astroglial cells of adult rat brain. J. Histochem. Cytochem. 38, 1535-1539.
4. Chen P., Goldberg D. E., Kolb B., Lanser M. and Benowitz L. I. (2002) Inosine induces axonal rewiring and improves behavioral outcome after stroke. Proc. Natl. Acad. Sci. USA 99, 9031-9036.
5. Dale N., Pearson T. and Frenguelli B. G. (2000) Direct measurement of adenosine release during hypoxia in the CA1 region of the rat hippocampal slice. J. PhysioL 526, 143-155.
6. Doolette D. J. (1997) Mechanism of adenosine accumulation in the hippocampal slice during energy deprivation. Neurochem. Int. 30, 211-223.
7. Frenguelli B. G., Llaudet E. and Dale N. (2003) High-resolution real-time recording with microelectrode biosensors reveals novel aspects of adenosine release during hypoxia in rat hippocampal slices. J. Neurochem. 86, 1506-1515.
8. Geiger J. D., Parkinson F. E. and Kowaluk E. A. (1997) Regulators of endogenous adenosine levels as therapeutic agents, in Purinergic Approaches in Experimental Therapeutics (Jacobson K. A. and Jarvis M. F., eds), pp. 55-84. Wiley-Liss, Inc., New York.
9. Jin X., Shepherd R. K., Duling B. R. and Linden J. (1997) Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation. J. Clin. Invest. 100, 2849-2857.
10. Knecht K., Wiesmuller K. H., Gnau V., Jung G., Meyermann R., Todd K. G. and Hamprecht B. (2001) AMP deaminase in rat brain: localization in neurons and ependymal cells. J. Neurosci. Res. 66, 941-950.
11. Koizumi J. (1974) Glycogen in the central nervous system. Prog. Histochem. Cytochem. 6, 1-37.
12. von Lubitz D. K. J. E., Lin R. C. S., Popik P., Carter M. F. and Jacobson K. A. (1994) Adenosine A3 receptor stimulation and cerebral ischemia. Eur. J. Pharmacol. 263, 59-67.
13. Marquetant R., Desai N. M., Sabina R. L. and Holmes E. W. (1987) Evidence for sequential expression of multiple AMP deaminase isoforms during skeletal muscle development. Proc. Natl. Acad. Sci. USA 84, 2345-2349.
14. Mosmann T. (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63.
15. Parkinson F. E., Zhang Y. W., Shepel P. N., Greenway S. C., Peeling J. and Geiger J. D. (2000) Effects of nitrobenzylthioinosine on neuronal injury, adenosine levels, and adenosine receptor activity in rat forebrain ischemia. J. Neurochem. 75, 795-802.
16. Parkinson F. E., Sinclair C. J., Othman T., Haughey N. J. and Geiger J. D. (2002) Differences between rat primary cortical neurons and astrocytes in purine release evoked by ischemic conditions. Neuropharmacology 43, 836-846.
17. Phillis J. W. and O'Regan M. H. (1996) Effects of an inhibitor of adenosine deaminase, deoxycoformycin, and of nucleoside transport, propentofylline, on post-ischemic recovery of adenine nucleotides in rat brain. Neurochem. Res. 21, 347-353.
18. Phillis J. W., O'Regan M. H., Estevez A. Y., Song D. and VanderHeide S. J. (1996a) Cerebral energy metabolism during severe ischemia of varying duration and following reperfusion. J. Neurochem. 67, 1525-1531.
19. Phillis J. W., Smith Barbour M. and O'Regan M. H. (1996b) Changes in extracellular amino acid neurotransmitters and purines during and following ischemias of different durations in the rat cerebral cortex. Neurochem. Int. 29, 115-120.
20. Rosenberg P. A., Li Y., Le M. and Zhang Y. (2000) Nitric oxide-stimulated increase in extracellular adenosine accumulation in rat forebrain neurons in culture is associated with ATP hydrolysis and inhibition of adenosine kinase activity. J. Neurosci. 20, 6294-6301.
21. Sabri M. I. and Ochs S. (1971) Inhibition of glyceraldehyde-3-phosphate dehydrogenase in mammalian nerve by iodoacetic acid. J. Neurochem. 18, 1509-1514.
22. Schrader J. and Gerlach E. (1976) Compartmentation of cardiac adenine nucleotides and formation of adenosine. Pflugers Arch. 367, 129-135.
23. Shulman R. G., Hyder F. and Rothman D. L. (2001) Cerebral energetics and the glycogen shunt: neurochemical basis of functional imaging. Proc. Natl Acad. Sci. USA 98, 6417-6422.
24. Sinclair C. J., LaRiviere C. G., Young J. D., Cass C. E., Baldwin S. A. and Parkinson F. E. (2000) Purine uptake and release in rat C6 glioma cells: nucleoside transport and purine metabolism under ATP-depleting conditions. J. Neurochem. 75, 1528-1538.
25. Sinclair C. J. D., Othman T., Haughey N. J., Geiger J. D. and Parkinson F. E. (2003) Erratum to 'Differences between rat primary cortical neurons and astrocytes in purine release evoked by ischemic conditions' [Neuropharmacology (2002) 42, 836-845]. Neuropharmacology 44, 115.
26. Sinclair C. J. D., Othman T., Haughey N. J., Geiger J. D. and Parkinson F. E. (2003) Erratum to 'Differences between rat primary cortical neurons and astrocytes in purine release evoked by ischemic conditions' [Neuropharmacology (2002) 42, 836-845]. Neuropharmacology 44, 115.
27. Van Reempts J., Van Deuren B., Haseldonckx M., Van d. V., Thone F. and Borgers M. (1988) Purine nucleoside phosphorylase: a histochemical marker for glial cells. Brain Res. 462, 142-147.
28. Ward J. L., Sherali A., Mo Z. P. and Tse C. M. (2000) Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine. J. Biol. Chem. 275, 8375-8381.
29. Wu M. M., You S. W., Hou B., Jiao X. Y., Li Y. Y. and Ju G. (2003) Effects of inosine on axonal regeneration of axotomized retinal ganglion cells in adult rats. Neurosci. Lett. 341, 84-86.
30. Zoref-Shani E., Bromberg Y., Lilling G., Gozes I., Brosh S., Sidi Y. and Sperling O. (1995) Developmental changes in purine nucleotide metabolism in cultured rat astroglia. Int. J. Dev. Neurosci. 13, 887-896.