Benign Fibroblastic Polyps of the Colon: A Histologic, Immunohistochemical, and Ultrastructural Study

American Journal of Surgical Pathology

Volumn 28, Issue 3, 2004, Pages 374-378

  Eslami Varzaneh, Fatima ^a   Washington, Kay ^b   Robert, Marie E ^a   Kashgarian, Michael ^a   Goldblum, John R ^c   Jain, Dhanpat ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Colon; Fibroblastic polyps; Mucosal polyps

Indexed keywords

ACTIN; CD31 ANTIGEN; CD34 ANTIGEN; DESMIN; EPITHELIAL MEMBRANE ANTIGEN; PROTEIN BCL 2; PROTEIN S 100; STEM CELL FACTOR; VIMENTIN;

ADULT; AGED; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL ORGANELLE; CELL PROLIFERATION; CELL ULTRASTRUCTURE; CLINICAL ARTICLE; CLINICAL FEATURE; COLON; COLON MUCOSA; COLON POLYP; COLON POLYPOSIS; CONTROLLED STUDY; CYTOLOGY; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; ELECTRON MICROSCOPY; ENDOSCOPY; FEMALE; FIBROBLAST; FIBROBLASTIC COLON POLYP; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTERMEDIATE FILAMENT; LAMINA PROPRIA; MALE; MESENCHYME; MITOSIS; SPINDLE CELL;

ACTINS; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD34; BIOLOGICAL MARKERS; COLONIC POLYPS; FEMALE; FIBROBLASTS; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MALE; MIDDLE AGED; ORGANELLES;

EID: 1442280363     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-200403000-00010     Document Type: Article

References (23)

1. Chilosi M, Facchetti F, Dei Tos AP. et al. Bcl-2 expression in pleural and extrapleural solitary fibrous tumors. J Pathol. 1997;181:362-367.
2. Daimaru Y, Kido H, Hashimoto H, et al. Benign schwannoma of the gastrointestinal tract: a clinicopathologic and Immunohistochemical study. Hum Pathol. 1988;19:257-264.
3. Erdman SH, Barnard JA. Gastrointestinal polyps and polyposis syndromes in children. Curr Opin Pediatr. 2002;14:576-582.
4. Groisman GM, Polak-Charcon S. Fibroepithelial polyps of the anus: a histologic, immunohistochemical, and ultrastructural study, including comparison with the normal anal subepithelial layer. Am J Surg Pathol. 1998;22:70-76.
5. Hasegawa T, Yang P, Kagawa N, et al. CD34 expression by inflammatory fibroid polyps of the stomach. Mod Pathol. 1997;10:451-456.
6. Hirose T, Takayuki T, Shimada T, et al. Immunohistochemical demonstration of EMA/Glut1-positive perineurial cells and CD34-positive fibroblastic cells in peripheral nerve sheath tumors. Mod Pathol. 2003;16;293-298.
7. Kaye GI, Pascal RR, Lane N. The colonic pericryptal fibroblastic sheath: replication, migration and cytodifferentiation of mesenchymal cell system in adult tissue: replication and differentiation in hyperplastic and adenomatous polyps. Gastroenterology. 1971;60:515-536.
8. Khan A, Shrier I, Gordon PH. The changed histologic paradigm of colorectal polyps. Surg Endosc. 2002;16:436-440.
9. Kim MK, Higgins J, Cho EY, et al. Expression of CD 34, Bcl-2 and kit in inflammatory fibroid polyps of the gastrointestinal tract. Appl. Immunohistochem. 2000;8:147-153.
10. Kindblom LG, Remotti HE, Aldenborg F, et al. Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol. 1998;152:1259-1269.
11. Makhlouf HR, Sobin LH. Inflammatory myofibroblastic tumors (inflammatory pseudotumors) of the gastrointestinal tract: how closely are they related to inflammatory fibroid polyps? Hum Pathol. 2002;33:307-315.
12. Miettinen M, Sarlomo-Rikala M, Sobin LH, et al. Gastrointestinal tumors and leiomyosarcoma in the colon. Am J Surg Pathol. 2000;24:1339-1352.
13. Miettinen M, Shekitka KM, Sobin LH. Schwannomas in the colon and rectum: a clinicopathologic and Immunohistochemical study of 20 cases. Aro J Surg Pathol. 2001;25:846-855.
14. Miettinen M, Sarlomo-Rikala M, Sobin LH, et al. Esophageal stromal tumors: a clinicopathologic, immunohistochemical, and molecular genetic study of 17 cases and comparison with esophageal leiomyoma and leiomyosarcomas. Am J Surg Pathol. 2000;24:211-222.
15. Morgan BK, Compton CC, Talbert M, et al. Benign smooth muscle tumors of the gastrointestinal tract: a 24 year experience. Ann Surg. 1990;211:63-66.
16. Moyana TN, Friesen R, Tan LK. Colorectal smooth muscle tumors: a pathologic study with immunohistochemistry and histomorphometry. Arch Pathol Lab Med. 1991;115:1016-1021.
17. Place RJ, Simmang CL. Hyperplastic-adenomatous polyposis syndrome. J Am Coll Surg. 1999;188:503-507.
18. Perentes E, Nakagawa Y, Ross GW, et al. Expression of epithelial membrane antigen in perineurial cells and their derivatives: an immunohistochemical study with multiple markers. Acta Neuropathol (Berl). 1987;75:160-165.
19. Sarlomo-Rikala M, Kovatich A, Barusevicius A, et al. CD 117: A sensitive marker for gastrointestinal stromal tumors that is more specific than CD34. Mod Pathol. 1998;11:728-734.
20. Suster S, Fisher C, Moran CA. Expression of bcl-2 oncoprotein in benign and malignant spindle cell tumors of the soft tissue, skin, serosal surfaces and gastrointestinal tract. Am J Surg Pathol. 1998;22:863-872.
21. Vagra Z, Caduff R. Fibroepithelial polyp of the uterine cervix. Hispathology. 1999;34:375-376.
22. Van de Rijn M, Rouse RV. Cd34: a review. Appl Immunohistochem. 1994;2:71-80.
23. Yantiss RK, Spiro IJ, Compton CC, et al. Gastrointestinal stromal tumor versus intra-abdominal fibromatosis of the bowel: a clinically important differential diagnosis. Am J Surg Pathol. 2000;24:947-957.