Pharmacokinetics of tacrolimus and mycophenolic acid are altered, but recover at different times during hepatic regeneration in rats

Drug Metabolism and Disposition

Volumn 33, Issue 3, 2005, Pages 329-335

  Tian, Hui ^a   Ou, Junhai ^a   Strom, Stephen C ^b   Venkataramanan, Raman ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCURONIDE; MYCOPHENOLIC ACID; TACROLIMUS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG ELIMINATION; DRUG METABOLISM; LIVER REGENERATION; LIVER RESECTION; MALE; METABOLIC CLEARANCE RATE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; GLUCURONATES; GLUCURONIDES; HEPATECTOMY; IMMUNOSUPPRESSIVE AGENTS; INTESTINE, SMALL; KIDNEY; LIVER; LIVER REGENERATION; MALE; MICROSOMES; MICROSOMES, LIVER; MODELS, ANIMAL; MYCOPHENOLIC ACID; P-GLYCOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TACROLIMUS; TIME FACTORS;

EID: 14044278151     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.104.002287     Document Type: Article

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