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Volumn 3, Issue 1, 2005, Pages 51-60

Interrupting highly active antiretroviral therapy in patients with HIV

Author keywords

Antiretroviral; Antiretroviral treatment; CD4 guided treatment; Highly active antiretroviral therapy; HIV 1; Non nucleoside reverse transcriptase inhibitors; Nucleoside reverse transcriptase inhibitors; Protease inhibitors; Scheduled treatment interruption; Structured treatment interruption

Indexed keywords

ANTIRETROVIRUS AGENT; CHOLESTEROL; DIDANOSINE; EFAVIRENZ; HYDROXYUREA; INDINAVIR; INTERLEUKIN 2; LAMIVUDINE; NEVIRAPINE; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; STAVUDINE; TRIACYLGLYCEROL; VIRUS RNA; ZIDOVUDINE;

EID: 14044268795     PISSN: 14787210     EISSN: None     Source Type: Journal    
DOI: 10.1586/14787210.3.1.51     Document Type: Review
Times cited : (5)

References (69)
  • 1
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
    • HIV Outpatient Study Investigators
    • Palella FJ Jr, Delaney KM, Moorman AC et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N. Engl. J. Med. 338(13), 853-860 (1998).
    • (1998) N. Engl. J. Med. , vol.338 , Issue.13 , pp. 853-860
    • Palella Jr., F.J.1    Delaney, K.M.2    Moorman, A.C.3
  • 2
    • 9844238154 scopus 로고    scopus 로고
    • Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: Prospective multicentre study. Swiss HIV Cohort Study
    • Egger M, Hirschel B, Francioli P et al. Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: prospective multicentre study. Swiss HIV Cohort Study. Br. Med. J. 315(7117), 1194-1199 (1997).
    • (1997) Br. Med. J. , vol.315 , Issue.7117 , pp. 1194-1199
    • Egger, M.1    Hirschel, B.2    Francioli, P.3
  • 3
    • 0035869435 scopus 로고    scopus 로고
    • The cost effectiveness of combination antiretroviral therapy for HIV disease
    • Freedberg KA, Losina E, Weinstein MC et al. The cost effectiveness of combination antiretroviral therapy for HIV disease. N. Engl. J. Med. 344(11), 824-831 (2001).
    • (2001) N. Engl. J. Med. , vol.344 , Issue.11 , pp. 824-831
    • Freedberg, K.A.1    Losina, E.2    Weinstein, M.C.3
  • 4
    • 0032797992 scopus 로고    scopus 로고
    • Cost effectiveness of highly active antiretroviral therapy in HIV-infected patients. Swiss HIV Cohort Study
    • Sendi PP, Bucher HC, Harr T et al. Cost effectiveness of highly active antiretroviral therapy in HIV-infected patients. Swiss HIV Cohort Study. AIDS 13(9), 1115-1122 (1999).
    • (1999) AIDS , vol.13 , Issue.9 , pp. 1115-1122
    • Sendi, P.P.1    Bucher, H.C.2    Harr, T.3
  • 5
    • 0036736481 scopus 로고    scopus 로고
    • Potential benefit and limitations of a broad access to potent antiretroviral therapy in developing countries
    • Kaufmann GR, Smith D, Bucher HC et al. Potential benefit and limitations of a broad access to potent antiretroviral therapy in developing countries. Expert Opin. Investig. Drugs 11(9), 1303-1313 (2002).
    • (2002) Expert Opin. Investig. Drugs , vol.11 , Issue.9 , pp. 1303-1313
    • Kaufmann, G.R.1    Smith, D.2    Bucher, H.C.3
  • 7
    • 0038806648 scopus 로고    scopus 로고
    • Management of severely immunocompromised human immunodeficiency virus Type 1-infected African orphans with structured treatment interruption: Another kind of salvage therapy
    • Chakraborty R, Musoke R, Palakudy T, Cross AD, Agostino A. Management of severely immunocompromised human immunodeficiency virus Type 1-infected African orphans with structured treatment interruption: another kind of salvage therapy. Clin. Infect. Dis. 36(11), 1483-1485 (2003).
    • (2003) Clin. Infect. Dis. , vol.36 , Issue.11 , pp. 1483-1485
    • Chakraborty, R.1    Musoke, R.2    Palakudy, T.3    Cross, A.D.4    Agostino, A.5
  • 8
    • 0038204340 scopus 로고    scopus 로고
    • HIV lipodystrophy: Risk factors, pathogenesis, diagnosis and management
    • Carr A. HIV lipodystrophy: risk factors, pathogenesis, diagnosis and management. AIDS 17(Suppl. 1), S141-S148 (2003).
    • (2003) AIDS , vol.17 , Issue.SUPPL. 1
    • Carr, A.1
  • 9
    • 0142043925 scopus 로고    scopus 로고
    • An open-label, prospective, observational study of the incidence of coronary artery disease in patients with HIV infection receiving highly active antiretroviral therapy
    • Barbaro G, Di Lorenzo G, Cirelli A et al. An open-label, prospective, observational study of the incidence of coronary artery disease in patients with HIV infection receiving highly active antiretroviral therapy. Clin. Ther. 25(9), 2405-2418 (2003).
    • (2003) Clin. Ther. , vol.25 , Issue.9 , pp. 2405-2418
    • Barbaro, G.1    Di Lorenzo, G.2    Cirelli, A.3
  • 10
    • 0042768569 scopus 로고    scopus 로고
    • Risk factors for coronary heart disease in patients treated for human immunodeficiency virus infection compared with the general population
    • Saves M, Chene G, Ducimetiere P et al. Risk factors for coronary heart disease in patients treated for human immunodeficiency virus infection compared with the general population. Clin. Infect. Dis. 37(2), 292-298 (2003).
    • (2003) Clin. Infect. Dis. , vol.37 , Issue.2 , pp. 292-298
    • Saves, M.1    Chene, G.2    Ducimetiere, P.3
  • 11
    • 0037076029 scopus 로고    scopus 로고
    • Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV-infected patients
    • Cote HC, Brumme ZL, Craib KJ, et al. Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV-infected patients. N. Engl. J. Med. 346(11), 811-820 (2002).
    • (2002) N. Engl. J. Med. , vol.346 , Issue.11 , pp. 811-820
    • Cote, H.C.1    Brumme, Z.L.2    Craib, K.J.3
  • 12
    • 0035095255 scopus 로고    scopus 로고
    • Cellular immune response to human immunodeficiency virus
    • Norris PJ, Rosenberg ES. Cellular immune response to human immunodeficiency virus. AIDS 15(Suppl. 2), S16-S21 (2001).
    • (2001) AIDS , vol.15 , Issue.SUPPL. 2
    • Norris, P.J.1    Rosenberg, E.S.2
  • 13
    • 0034727073 scopus 로고    scopus 로고
    • Immune control of HIV-1 after early treatment of acute infection
    • Rosenberg ES, Altfeld M, Poon SH et al. Immune control of HIV-1 after early treatment of acute infection. Nature 407(6803), 523-526 (2000).
    • (2000) Nature , vol.407 , Issue.6803 , pp. 523-526
    • Rosenberg, E.S.1    Altfeld, M.2    Poon, S.H.3
  • 14
    • 0032719664 scopus 로고    scopus 로고
    • HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy
    • Ortiz GM, Mixon DF, Trkola A et al. HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy. J. Clin. Invest. 104(6), R13-R18 (1999).
    • (1999) J. Clin. Invest. , vol.104 , Issue.6
    • Ortiz, G.M.1    Mixon, D.F.2    Trkola, A.3
  • 15
    • 0038025296 scopus 로고    scopus 로고
    • A prospective trial of structured treatment interruptions in human immunodeficiency virus infection
    • Fagard C, Oxenius A, Gunthard H et al. A prospective trial of structured treatment interruptions in human immunodeficiency virus infection. Arch. Intern. Med. 163 (10), 1220-1226 (2003).
    • (2003) Arch. Intern. Med. , vol.163 , Issue.10 , pp. 1220-1226
    • Fagard, C.1    Oxenius, A.2    Gunthard, H.3
  • 16
    • 1242320996 scopus 로고    scopus 로고
    • Genotypic resistance tests for the management of structured therapeutic interruptions after multiple drug failure
    • Montroni M, Monforte AD. Genotypic resistance tests for the management of structured therapeutic interruptions after multiple drug failure. Scand. J. Infect. Dis. 35(Suppl. 106), 79-81 (2003).
    • (2003) Scand. J. Infect. Dis. , vol.35 , Issue.SUPPL. 106 , pp. 79-81
    • Montroni, M.1    Monforte, A.D.2
  • 17
    • 0036189290 scopus 로고    scopus 로고
    • Structured treatment interruptions in HIV/AIDS therapy
    • Lisziewicz J, Lori F. Structured treatment interruptions in HIV/AIDS therapy. Microbes Infect. 4(2), 207-214 (2002).
    • (2002) Microbes Infect. , vol.4 , Issue.2 , pp. 207-214
    • Lisziewicz, J.1    Lori, F.2
  • 18
    • 0033609174 scopus 로고    scopus 로고
    • Control of HIV despite the discontinuation of antiretroviral therapy
    • Lisziewicz J, Rosenberg E, Lieberman J et al. Control of HIV despite the discontinuation of antiretroviral therapy. N. Engl. J. Med. 340(21), 1683-1684 (1999).
    • (1999) N. Engl. J. Med. , vol.340 , Issue.21 , pp. 1683-1684
    • Lisziewicz, J.1    Rosenberg, E.2    Lieberman, J.3
  • 19
    • 0346850793 scopus 로고    scopus 로고
    • Predictors of plasma human immunodeficiency virus Type 1 RNA control after discontinuation of highly active antiretroviral therapy initiated at acute infection combined with structured treatment interruptions and immune-based therapies
    • Lafeuillade A, Poggi C, Hittinger G, Counillon E, Emilie D. Predictors of plasma human immunodeficiency virus Type 1 RNA control after discontinuation of highly active antiretroviral therapy initiated at acute infection combined with structured treatment interruptions and immune-based therapies. J. Infect. Dis. 188(10), 1426-1432 (2003).
    • (2003) J. Infect. Dis. , vol.188 , Issue.10 , pp. 1426-1432
    • Lafeuillade, A.1    Poggi, C.2    Hittinger, G.3    Counillon, E.4    Emilie, D.5
  • 21
    • 0028041344 scopus 로고
    • + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus Type 1 infection
    • + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus Type 1 infection. J. Virol. 68(9), 6103-6110 (1994).
    • (1994) J. Virol. , vol.68 , Issue.9 , pp. 6103-6110
    • Borrow, P.1    Lewicki, H.2    Hahn, B.H.3    Shaw, G.M.4    Oldstone, M.B.5
  • 22
    • 0030831656 scopus 로고    scopus 로고
    • Cytotoxic-T-cell responses, viral load, and disease progression in early human immunodeficiency virus Type 1 infection
    • Musey L, Hughes J, Schacker T, Shea T, Corey L, McElrath WJ. Cytotoxic-T-cell responses, viral load, and disease progression in early human immunodeficiency virus Type 1 infection. N. Engl. J. Med. 37(18), 1267-1274 (1997).
    • (1997) N. Engl. J. Med. , vol.37 , Issue.18 , pp. 1267-1274
    • Musey, L.1    Hughes, J.2    Schacker, T.3    Shea, T.4    Corey, L.5    McElrath, W.J.6
  • 23
    • 0034711393 scopus 로고    scopus 로고
    • Control of SIV rebound through structured treatment interruptions during early infection
    • Lori F, Lewis MG, Xu J, et al. Control of SIV rebound through structured treatment interruptions during early infection. Science 290(5496), 1591-1593 (2000).
    • (2000) Science , vol.290 , Issue.5496 , pp. 1591-1593
    • Lori, F.1    Lewis, M.G.2    Xu, J.3
  • 24
    • 0035910032 scopus 로고    scopus 로고
    • Short-cycle structured intermittent treatment of chronic HIV infection with highly active antiretroviral therapy: Effects on virologic, immunologic, and toxicity parameters
    • Dybul M, Chun TW, Yoder C et al. Short-cycle structured intermittent treatment of chronic HIV infection with highly active antiretroviral therapy: effects on virologic, immunologic, and toxicity parameters. Proc. Natl Acad. Sci. USA 98(26), 15161-15166 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.26 , pp. 15161-15166
    • Dybul, M.1    Chun, T.W.2    Yoder, C.3
  • 25
    • 2542467589 scopus 로고    scopus 로고
    • A proof-of-concept study of short-cycle intermittent antiretroviral therapy with a once-daily regimen of didanosine, lamivudine, and efavirenz for the treatment of chronic HIV infection
    • Dybul M, Nies-Kraske E, Dewar R et al. A proof-of-concept study of short-cycle intermittent antiretroviral therapy with a once-daily regimen of didanosine, lamivudine, and efavirenz for the treatment of chronic HIV infection. J. Infect. Dis. 189(11), 1974-1982 (2004).
    • (2004) J. Infect. Dis. , vol.189 , Issue.11 , pp. 1974-1982
    • Dybul, M.1    Nies-Kraske, E.2    Dewar, R.3
  • 26
    • 14044268411 scopus 로고    scopus 로고
    • Comparing CD4-guided vs. 1 week on-1 week off vs. continuous HAART in 74 patients with chronic HIV infection: Week 108 results
    • Proceedings of the XV International AIDS Conference. Bangkok, Thailand, 11-16 July (Abstract WeOrB1283)
    • Ananworanich J, Siangphoe U, Cardiello P et al. Comparing CD4-guided vs. 1 week on-1 week off vs. continuous HAART in 74 patients with chronic HIV infection: week 108 results. Proceedings of the XV International AIDS Conference. Bangkok, Thailand, 11-16 July 2004 (Abstract WeOrB1283).
    • (2004)
    • Ananworanich, J.1    Siangphoe, U.2    Cardiello, P.3
  • 27
    • 10744229013 scopus 로고    scopus 로고
    • Failures of 1 week on-1 week: Off antiretroviral therapies in a randomized trial
    • Ananworanich J, Nuesch R, Le Braz M et al. Failures of 1 week on-1 week: off antiretroviral therapies in a randomized trial. AIDS 17(15), F33-F37 (2003).
    • (2003) AIDS , vol.17 , Issue.15
    • Ananworanich, J.1    Nuesch, R.2    Le Braz, M.3
  • 28
    • 14044277784 scopus 로고    scopus 로고
    • Symposium on structured treatment interruptions
    • Bangkok, Thailand, 11-16 July (Abstract TuSy189)
    • Dybul M. Symposium on structured treatment interruptions. Proceedings of the XV International AIDS Conference. Bangkok, Thailand, 11-16 July 2004 (Abstract TuSy189).
    • (2004) Proceedings of the XV International AIDS Conference
    • Dybul, M.1
  • 29
    • 0042658343 scopus 로고    scopus 로고
    • Long-cycle structured intermittent versus continuous highly active antiretroviral therapy for the treatment of chronic infection with human immunodeficiency virus: Effects on drug toxicity and on immunologic and virologic parameters
    • Dybul M, Nies-Kraske E, Daucher M et al. Long-cycle structured intermittent versus continuous highly active antiretroviral therapy for the treatment of chronic infection with human immunodeficiency virus: effects on drug toxicity and on immunologic and virologic parameters. J. Infect. Dis. 188(3), 388-396 (2003).
    • (2003) J. Infect. Dis. , vol.188 , Issue.3 , pp. 388-396
    • Dybul, M.1    Nies-Kraske, E.2    Daucher, M.3
  • 30
    • 14044263161 scopus 로고    scopus 로고
    • Symposium on structured treatment interruptions
    • Bangkok, Thailand, 11-16 July (Abstract TuSy188)
    • Delfraissy J. Symposium on structured treatment interruptions. Proceedings of the XV International AIDS Conference. Bangkok, Thailand, 11-16 July 2004 (Abstract TuSy188).
    • (2004) Proceedings of the XV International AIDS Conference
    • Delfraissy, J.1
  • 31
    • 1642339461 scopus 로고    scopus 로고
    • Effect of prolonged discontinuation of successful antiretroviral therapy on CD4 T-cells: A controlled, prospective trial
    • Maggiolo F, Ripamonti D, Gregis G, Quinzan G, Callegaro A. Suter F. Effect of prolonged discontinuation of successful antiretroviral therapy on CD4 T-cells: a controlled, prospective trial. AIDS 18(3), 439-446 (2004).
    • (2004) AIDS , vol.18 , Issue.3 , pp. 439-446
    • Maggiolo, F.1    Ripamonti, D.2    Gregis, G.3    Quinzan, G.4    Callegaro, A.5    Suter, F.6
  • 32
    • 14044265929 scopus 로고    scopus 로고
    • Biphasic decline of CD4 cell count during scheduled treatment interruptions
    • (In press)
    • Fagard C, Bandelier C, Ananworanich J et al. Biphasic decline of CD4 cell count during scheduled treatment interruptions. AIDS (2004) (In press).
    • (2004) AIDS
    • Fagard, C.1    Bandelier, C.2    Ananworanich, J.3
  • 33
    • 0037083001 scopus 로고    scopus 로고
    • Resuppression of virus load after interruption in treatment with nevirapine and two nucleoside reverse-transcriptase inhibitors
    • Yozviak JL, Doerfler RE, Woodward WC. Resuppression of virus load after interruption in treatment with nevirapine and two nucleoside reverse-transcriptase inhibitors. Clin. Infect. Dis. 34(4), 547-550 (2002).
    • (2002) Clin. Infect. Dis. , vol.34 , Issue.4 , pp. 547-550
    • Yozviak, J.L.1    Doerfler, R.E.2    Woodward, W.C.3
  • 34
    • 4544246769 scopus 로고    scopus 로고
    • Relationship between efavirenz pharmacokinetics, side effects, drug discontinuation, virologic response, and race: Results from ACTG A5095/A5097s
    • San Fransisco, CA, USA, 8-11 February (Abstract 132)
    • Ribaudo H, Clifford D, Gulick RM et al. Relationship between efavirenz pharmacokinetics, side effects, drug discontinuation, virologic response, and race: results from ACTG A5095/A5097s. Proceedings of the 11th Conference on Retroviruses and Opportunistic Infections. San Fransisco, CA, USA, 8-11 February 2004 (Abstract 132).
    • (2004) Proceedings of the 11th Conference on Retroviruses and Opportunistic Infections
    • Ribaudo, H.1    Clifford, D.2    Gulick, R.M.3
  • 35
    • 3142770977 scopus 로고    scopus 로고
    • Stop study: After discontinuation of efavirenz, plasma concentrations may persist for 2 weeks or longer
    • San Fransisco, CA, USA, 8-11 February (Abstract 131)
    • Taylor S, Allen S, Fidler S et al. Stop study: after discontinuation of efavirenz, plasma concentrations may persist for 2 weeks or longer. Proceedings of the 11th Conference on Retroviruses and Opportunistic Infections. San Fransisco, CA, USA, 8-11 February 2004 (Abstract 131).
    • (2004) Proceedings of the 11th Conference on Retroviruses and Opportunistic Infections
    • Taylor, S.1    Allen, S.2    Fidler, S.3
  • 36
    • 3142762317 scopus 로고    scopus 로고
    • Intrapartum exposure to nevirapine and subsequent maternal responses to nevirapine-based antiretroviral therapy
    • Jourdain G, Ngo-Giang-Huong N, Le Coeur S et al.. Intrapartum exposure to nevirapine and subsequent maternal responses to nevirapine-based antiretroviral therapy. N. Engl. J. Med. 351(3), 229-240 (2004).
    • (2004) N. Engl. J. Med. , vol.351 , Issue.3 , pp. 229-240
    • Jourdain, G.1    Ngo-Giang-Huong, N.2    Le Coeur, S.3
  • 37
    • 0037414987 scopus 로고    scopus 로고
    • A cytostatic drug improves control of HIV-1 replication during structured treatment interruptions: A randomized study
    • Garcia F, Plana M, Arnedo M et al. A cytostatic drug improves control of HIV-1 replication during structured treatment interruptions: a randomized study. AIDS 17(1), 43-51 (2003).
    • (2003) AIDS , vol.17 , Issue.1 , pp. 43-51
    • Garcia, F.1    Plana, M.2    Arnedo, M.3
  • 38
    • 12144290358 scopus 로고    scopus 로고
    • Strategies to decrease viral load rebound, and prevent loss of CD4 and onset of resistance during structured treatment interruptions
    • Foli A, Maserati R, Barasolo G et al. Strategies to decrease viral load rebound, and prevent loss of CD4 and onset of resistance during structured treatment interruptions. Antivir. Ther. 9(1), 123-132 (2004).
    • (2004) Antivir. Ther. , vol.9 , Issue.1 , pp. 123-132
    • Foli, A.1    Maserati, R.2    Barasolo, G.3
  • 39
    • 0034071659 scopus 로고    scopus 로고
    • Structured treatment interruption in chronically HIV-1 infected patients after long-term viral suppression
    • Ruiz L, Martinez-Picado J, Romeu J et al. Structured treatment interruption in chronically HIV-1 infected patients after long-term viral suppression. AIDS 14(4), 397-403 (2000).
    • (2000) AIDS , vol.14 , Issue.4 , pp. 397-403
    • Ruiz, L.1    Martinez-Picado, J.2    Romeu, J.3
  • 40
    • 0035915372 scopus 로고    scopus 로고
    • Structured treatment interruptions for the management of HIV infection
    • Lori F, Lisziewicz J. Structured treatment interruptions for the management of HIV infection. J. Am. Med. Assoc. 286(23), 2981-2987 (2001).
    • (2001) J. Am. Med. Assoc. , vol.286 , Issue.23 , pp. 2981-2987
    • Lori, F.1    Lisziewicz, J.2
  • 41
    • 0142061996 scopus 로고    scopus 로고
    • Aseptic meningitis and acute HIV syndrome after interruption of antiretroviral therapy: Implications for structured treatment interruptions
    • Worthington MG, Ross JJ. Aseptic meningitis and acute HIV syndrome after interruption of antiretroviral therapy: implications for structured treatment interruptions. AIDS 17(14), 2145-2146 (2003).
    • (2003) AIDS , vol.17 , Issue.14 , pp. 2145-2146
    • Worthington, M.G.1    Ross, J.J.2
  • 42
    • 0035816358 scopus 로고    scopus 로고
    • Cerebrospinal fluid response to structured treatment interruption after virologic failure
    • Price RW, Paxinos EE, Grant RM et al. Cerebrospinal fluid response to structured treatment interruption after virologic failure. AIDS 15(10), 1251-1259 (2001).
    • (2001) AIDS , vol.15 , Issue.10 , pp. 1251-1259
    • Price, R.W.1    Paxinos, E.E.2    Grant, R.M.3
  • 43
    • 0442282114 scopus 로고    scopus 로고
    • A case of multiorgan failure following interruption of antiretroviral treatment
    • Crespo M, Paradineiro JC, Ribera E et al. A case of multiorgan failure following interruption of antiretroviral treatment. Eur. J. Clin. Microbiol. Infect. Dis. 23(1), 63-65 (2004).
    • (2004) Eur. J. Clin. Microbiol. Infect. Dis. , vol.23 , Issue.1 , pp. 63-65
    • Crespo, M.1    Paradineiro, J.C.2    Ribera, E.3
  • 44
    • 0041329696 scopus 로고    scopus 로고
    • Recurring thrombocytopenia associated with structured treatment interruption in patients with human immunodeficiency virus infection
    • Ananworanich J, Phanuphak N, Nuesch R et al. Recurring thrombocytopenia associated with structured treatment interruption in patients with human immunodeficiency virus infection. Clin. Infect. Dis. 37(5), 723-725 (2003).
    • (2003) Clin. Infect. Dis. , vol.37 , Issue.5 , pp. 723-725
    • Ananworanich, J.1    Phanuphak, N.2    Nuesch, R.3
  • 45
    • 0742324942 scopus 로고    scopus 로고
    • Attenuated and nonproductive viral transcription in the lymphatic tissue of HIV-1-infected patients receiving potent antiretroviral therapy
    • Fischer M, Joos B, Wong JK et al. Attenuated and nonproductive viral transcription in the lymphatic tissue of HIV-1-infected patients receiving potent antiretroviral therapy. J. Infect. Dis. 189(2), 273-285 (2004).
    • (2004) J. Infect. Dis. , vol.189 , Issue.2 , pp. 273-285
    • Fischer, M.1    Joos, B.2    Wong, J.K.3
  • 46
    • 0037324326 scopus 로고    scopus 로고
    • Enhanced risk of HIV sexual transmission during structured treatment interruption
    • Teicher E, Casagrande T, Vittecoq D. Enhanced risk of HIV sexual transmission during structured treatment interruption. Sex Transm. Infect. 79(1), 74(2003).
    • (2003) Sex. Transm. Infect. , vol.79 , Issue.1 , pp. 74
    • Teicher, E.1    Casagrande, T.2    Vittecoq, D.3
  • 47
    • 0037227585 scopus 로고    scopus 로고
    • Emergence of cytotoxic T-lymphocyte escape mutants following antiretroviral treatment suspension in rhesus macaques infected with SIV mac251
    • Nacsa J, Stanton J, Kunstman KJ et al. Emergence of cytotoxic T-lymphocyte escape mutants following antiretroviral treatment suspension in rhesus macaques infected with SIV mac251. Virology 305(1), 210-218 (2003).
    • (2003) Virology , vol.305 , Issue.1 , pp. 210-218
    • Nacsa, J.1    Stanton, J.2    Kunstman, K.J.3
  • 48
    • 0037105711 scopus 로고    scopus 로고
    • Acute human immunodeficiency virus replication causes a rapid and persistent impairment of Vγ9Vδ2 T-cells in chronically infected patients undergoing structured treatment interruption
    • Martini F, Poccia F, Goletti D et al. Acute human immunodeficiency virus replication causes a rapid and persistent impairment of Vγ9Vδ2 T-cells in chronically infected patients undergoing structured treatment interruption. J. Infect. Dis. 186(6), 847-850 (2002).
    • (2002) J. Infect. Dis. , vol.186 , Issue.6 , pp. 847-850
    • Martini, F.1    Poccia, F.2    Goletti, D.3
  • 49
    • 0345490972 scopus 로고    scopus 로고
    • + T-cell differentiation phenotype during structured treatment interruption in patients with chronic HIV-1 infection
    • + T-cell differentiation phenotype during structured treatment interruption in patients with chronic HIV-1 infection. J. Acquir. Immune Defic. Syndr. 34(5), 475-481 (2003).
    • (2003) J. Acquir. Immune Defic. Syndr. , vol.34 , Issue.5 , pp. 475-481
    • Alexander, T.H.1    Ortiz, G.M.2    Wellons, M.F.3
  • 50
    • 0037131341 scopus 로고    scopus 로고
    • Virologic and immunological effects of short-course antiretroviral therapy in primary HIV infection
    • Fidler S, Oxenius A, Brady M et al. Virologic and immunological effects of short-course antiretroviral therapy in primary HIV infection. AIDS 16(15), 2049-2054 (2002).
    • (2002) AIDS , vol.16 , Issue.15 , pp. 2049-2054
    • Fidler, S.1    Oxenius, A.2    Brady, M.3
  • 51
    • 10744223424 scopus 로고    scopus 로고
    • Emergence of minor populations of human immunodeficiency virus Type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions
    • Metzner KJ, Bonhoeffer S, Fischer M et al. Emergence of minor populations of human immunodeficiency virus Type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions. J. Infect. Dis. 188(10), 1433-1443 (2003).
    • (2003) J. Infect. Dis. , vol.188 , Issue.10 , pp. 1433-1443
    • Metzner, K.J.1    Bonhoeffer, S.2    Fischer, M.3
  • 52
    • 0037436291 scopus 로고    scopus 로고
    • Persistence of drug-resistant HIV-1 after a structured treatment interruption and its impact on treatment response
    • Deeks SG, Grant RM, Wrin T et al. Persistence of drug-resistant HIV-1 after a structured treatment interruption and its impact on treatment response. AIDS 17(3), 361-370 (2003).
    • (2003) AIDS , vol.17 , Issue.3 , pp. 361-370
    • Deeks, S.G.1    Grant, R.M.2    Wrin, T.3
  • 53
    • 0037066371 scopus 로고    scopus 로고
    • Selection of drug-resistant HIV-1 mutants in response to repeated structured treatment interruptions
    • Martinez-Picado J, Morales-Lopetegi K, Wrin T et al. Selection of drug-resistant HIV-1 mutants in response to repeated structured treatment interruptions. AIDS 16(6), 895-899 (2002).
    • (2002) AIDS , vol.16 , Issue.6 , pp. 895-899
    • Martinez-Picado, J.1    Morales-Lopetegi, K.2    Wrin, T.3
  • 54
    • 14044258098 scopus 로고    scopus 로고
    • Development of resistance after CD4 guided structured treatment interruptions in HIV infected patients treated with highly active antiretroviral therapy after dual nucleoside treatment
    • (In Press)
    • Nuesch R, Ananworanich A, Sirivichayakul S et al. Development of resistance after CD4 guided structured treatment interruptions in HIV infected patients treated with highly active antiretroviral therapy after dual nucleoside treatment. Clin. Infect. Dis. (2004) (In Press).
    • (2004) Clin. Infect. Dis.
    • Nuesch, R.1    Ananworanich, A.2    Sirivichayakul, S.3
  • 55
    • 0242268457 scopus 로고    scopus 로고
    • Drug resistance mutations during structured treatment interruptions
    • Yerly S, Fagard C, Gunthard HF, Hirschel B, Perrin L. Drug resistance mutations during structured treatment interruptions. Antivir. Ther. 8(5), 411-415 (2003).
    • (2003) Antivir. Ther. , vol.8 , Issue.5 , pp. 411-415
    • Yerly, S.1    Fagard, C.2    Gunthard, H.F.3    Hirschel, B.4    Perrin, L.5
  • 56
    • 0038637314 scopus 로고    scopus 로고
    • Prevalence of unsafe sexual behavior among HIV-infected individuals: The Swiss HIV Cohort Study
    • Wolf K, Young J, Rickenbach M et al. Prevalence of unsafe sexual behavior among HIV-infected individuals: the Swiss HIV Cohort Study. J. Acquir. Immune Defic. Syndr. 33(4), 494-499 (2003).
    • (2003) J. Acquir. Immune Defic. Syndr. , vol.33 , Issue.4 , pp. 494-499
    • Wolf, K.1    Young, J.2    Rickenbach, M.3
  • 57
    • 0036183470 scopus 로고    scopus 로고
    • Structured treatment interruption in patients infected with HIV: A new approach to therapy
    • Gulick RM. Structured treatment interruption in patients infected with HIV: a new approach to therapy. Drugs 62(2), 245-253 (2002).
    • (2002) Drugs , vol.62 , Issue.2 , pp. 245-253
    • Gulick, R.M.1
  • 58
    • 0037032905 scopus 로고    scopus 로고
    • Expansion of preterminally differentiated CD8 T-cells in chronic HIV-positive patients presenting a rapid viral rebound during structured treatment interruption
    • D'Offizi G, Montesano C, Agrati C et al. Expansion of preterminally differentiated CD8 T-cells in chronic HIV-positive patients presenting a rapid viral rebound during structured treatment interruption. AIDS 16(18), 2431-2438 (2002).
    • (2002) AIDS , vol.16 , Issue.18 , pp. 2431-2438
    • D'Offizi, G.1    Montesano, C.2    Agrati, C.3
  • 59
    • 0037108925 scopus 로고    scopus 로고
    • Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection
    • Oxenius A, Price DA, Gunthard HF et al. Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection. Proc. Natl Acad. Sci. USA 99(21), 13747-13752 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , Issue.21 , pp. 13747-13752
    • Oxenius, A.1    Price, D.A.2    Gunthard, H.F.3
  • 60
    • 0036784585 scopus 로고    scopus 로고
    • Human immunodeficiency virus-specific CD8(+) T-cell responses do not predict viral growth and clearance rates during structured intermittent antiretroviral therapy
    • Oxenius A, McLean AR, Fischer M et al. Human immunodeficiency virus-specific CD8(+) T-cell responses do not predict viral growth and clearance rates during structured intermittent antiretroviral therapy. J. Virol. 76(20), 10169-10176 (2002).
    • (2002) J. Virol. , vol.76 , Issue.20 , pp. 10169-10176
    • Oxenius, A.1    McLean, A.R.2    Fischer, M.3
  • 62
    • 2942596327 scopus 로고    scopus 로고
    • Structured treatment interruptions in HIV infection: Benefit or disappointment?
    • Oxenius A. Hirschel B. Structured treatment interruptions in HIV infection: benefit or disappointment? Expert Rev. Anti Infect. Ther. 1(1), 129-139 (2003).
    • (2003) Expert Rev. Anti Infect. Ther. , vol.1 , Issue.1 , pp. 129-139
    • Oxenius, A.1    Hirschel, B.2
  • 63
    • 0037661201 scopus 로고    scopus 로고
    • Kinetics of disappearance of resistance mutations and reappearance of wild-type during structured treatment interruptions
    • Halfon P, Durant J, Clevenbergh P et al. Kinetics of disappearance of resistance mutations and reappearance of wild-type during structured treatment interruptions. AIDS 17(9), 1351-1361 (2003).
    • (2003) AIDS , vol.17 , Issue.9 , pp. 1351-1361
    • Halfon, P.1    Durant, J.2    Clevenbergh, P.3
  • 64
    • 0347695016 scopus 로고    scopus 로고
    • Predictors of sustained response to therapy resumption after treatment interruption in HIV-infected patients failing antiretroviral therapy
    • Gianotti N, Soria A, Galli L et al. Predictors of sustained response to therapy resumption after treatment interruption in HIV-infected patients failing antiretroviral therapy. J. Med. Virol. 72(2), 181-186 (2004).
    • (2004) J. Med. Virol. , vol.72 , Issue.2 , pp. 181-186
    • Gianotti, N.1    Soria, A.2    Galli, L.3
  • 65
    • 0036888919 scopus 로고    scopus 로고
    • Viral evolution during structured treatment interruptions in chronically human immunodeficiency virus-infected individuals
    • Martinez-Picado J, Frost SD, Izquierdo N et al. Viral evolution during structured treatment interruptions in chronically human immunodeficiency virus-infected individuals. J. Virol. 76(23), 12344-12348 (2002).
    • (2002) J. Virol. , vol.76 , Issue.23 , pp. 12344-12348
    • Martinez-Picado, J.1    Frost, S.D.2    Izquierdo, N.3
  • 66
    • 0042431969 scopus 로고    scopus 로고
    • Structured treatment interruption in patients with multi-drug resistant human immunodeficiency virus
    • Lawrence J, Mayers DL, Hullsiek KH et al. Structured treatment interruption in patients with multi-drug resistant human immunodeficiency virus. N. Engl. J. Med. 349(9), 837-846 (2003).
    • (2003) N. Engl. J. Med. , vol.349 , Issue.9 , pp. 837-846
    • Lawrence, J.1    Mayers, D.L.2    Hullsiek, K.H.3
  • 67
    • 0142074332 scopus 로고    scopus 로고
    • Role of structured treatment interruption before a 5-drug salvage antiretroviral regimen: The Retrogene Study
    • Ruiz L, Ribera E, Bonjoch A et al. Role of structured treatment interruption before a 5-drug salvage antiretroviral regimen: the Retrogene Study. J. Infect. Dis. 188(7), 977-985 (2003).
    • (2003) J. Infect. Dis. , vol.188 , Issue.7 , pp. 977-985
    • Ruiz, L.1    Ribera, E.2    Bonjoch, A.3
  • 68
    • 10744223335 scopus 로고    scopus 로고
    • Benefit of treatment interruption in HIV-infected patients with multiple therapeutic failures: A randomized controlled trial (ANRS 097)
    • Katlama C, Dominguez S, Gourlain K et al. Benefit of treatment interruption in HIV-infected patients with multiple therapeutic failures: a randomized controlled trial (ANRS 097). AIDS 18(2), 217-226 (2004).
    • (2004) AIDS , vol.18 , Issue.2 , pp. 217-226
    • Katlama, C.1    Dominguez, S.2    Gourlain, K.3
  • 69
    • 0041429533 scopus 로고    scopus 로고
    • Beware of drug holidays before HIV salvage therapy
    • Hirschel B. Beware of drug holidays before HIV salvage therapy. N. Engl. J. Med. 349(9), 827-828 (2003).
    • (2003) N. Engl. J. Med. , vol.349 , Issue.9 , pp. 827-828
    • Hirschel, B.1


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