Differential role of progesterone receptor isoforms in the transcriptional regulation of human gonadotropin-releasing hormone I (GnRH I) receptor, GnRH I, and GnRH II

Journal of Clinical Endocrinology and Metabolism

Volumn 90, Issue 2, 2005, Pages 1106-1113

  An, Beum Soo ^a   Choi, Jung Hye ^a   Choi, Kyung Chul ^a   Leung, Peter C K ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; GONADORELIN RECEPTOR; LUCIFERASE; MESSENGER RNA; MIFEPRISTONE; PROGESTERONE; PROGESTERONE RECEPTOR;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; GENETIC TRANSFECTION; GONADOTROPIN RELEASE; HUMAN; HUMAN CELL; MEDULLOBLASTOMA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; REPRODUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

BASE SEQUENCE; CELL LINE, TUMOR; CEREBELLAR NEOPLASMS; DNA PRIMERS; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; MEDULLOBLASTOMA; PLASMIDS; PROMOTER REGIONS (GENETICS); PROTEIN ISOFORMS; RECEPTORS, LHRH; RECEPTORS, PROGESTERONE; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSFECTION;

MAMMALIA;

EID: 14044250986     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-0318     Document Type: Article

References (56)

1. Peng C, Fan NC, Ligier M, Vaananen J, Leung PC 1994 Expression and regulation of gonadotropin-releasing hormone (GnRH) and GnRH receptor messenger ribonucleic acids in human granulosa-luteal cells. Endocrinology 135:1740-1746
2. Minaretzis D, Jakubowski M, Mortola J, Pavlou S 1995 Gonadotropin- releasing hormone receptor gene expression in human ovary and granulosalutein cells. J Clin Endocrinol Metab 80:430-434
3. Lin L, Roberts V, Yen S 1995 Expression of human gonadotropin-releasing hormone receptor gene in the placenta and its functional relationship to human chorionic gonadotropin secretion. J Clin Endocrinol Metab 80:580-585
4. Rang SK, Tai C-J, Nathwani PS, Choi K-C, Leung PCK 2001 Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone in human granulosa-luteal cells. Endocrinology 142:671-679
5. Bussenot I, Azoulay-Barjonet C, Parinaud J 1993 Modulation of the steroidogenesis of cultured human granulosa-lutein cells by gonadotropin- releasing hormone analogs. J Clin Endocrinol Metab 76:1376-1379
6. White RB, Eisen JA, Kasten TL, Fernald RD 1998 Second gene for gonadotropin-releasing hormone in humans. Proc Natl Acad Sci USA 95:305-309
7. Duval DL, Nelson SE, Clay CM 1997 The Tripartite basal enhancer of the gonadotropin-releasing hormone (GnRH) receptor gene promoter regulates cell-specific expression through a novel GnRH receptor activating sequence. Mol Endocrinol 11:1814-1821
8. Ngan ESW, Cheng PKW, Leung PCK, Chow BKC 1999 Steroidogenic factor-1 interacts with a gonadotrope-specific element within the first exon of the human gonadotropin-releasing hormone receptor gene to mediate gonadotrope-specific expression. Endocrinology 140:2452-2462
9. Khosravi S, Leung PC 2003 Differential regulation of gonadotropin- releasing hormone (GnRH)I and GnRHII messenger ribonucleic acid by gonadal steroids in human granulosa luteal cells. J Clin Endocrinol Metab 88:663-672
10. Bauer-Dantoin AC, Hollenberg AN, Jameson JL 1993 Dynamic regulation of gonadotropin-releasing hormone receptor mRNA levels in the anterior pituitary gland during the rat estrous cycle. Endocrinology 133:1911-1914
11. Funabashi T, Brooks PJ, Weesner GD, Pfaff DW 1994 Luteinizing hormone-releasing hormone receptor messenger ribonucleic acid expression in the rat pituitary during lactation and the estrous cycle. J Neuroendocrinol 6:261-266
12. Sakurai H, Adams BM, Adams TE 1997 Concentration of GnRH receptor and GnRH receptor mRNA in pituitary tissue of orchidectomized sheep: effect of oestradiol, progesterone, and progesterone withdrawal. J Endocrinol 152:91-98
13. Gore AC, Roberts JL 1997 Regulation of gonadotropin-releasing hormone gene expression in vivo and in vitro. Front Neuroendocrinol 18:209-245
14. Herbison AE 1998 Multimodal influence of estrogen upon gonadotropin-releasing hormone neurons. Endocr Rev 19:302-330
15. Chongthammakun S, Terasawa E 1993 Negative feedback effects of estrogen on luteinizing hormone-releasing hormone release occur in pubertal, but not prepubertal, ovariectomized female rhesus monkeys. Endocrinology 132:735-743
16. Sagrillo CA, Grattan DR, McCarthy MM, Selmanoff M 1996 Hormonal and neurotransmitter regulation of GnRH gene expression and related reproductive behaviors. Behav Genet 26:241-277
17. Schumacher M, Coirini H, Robert F, Guennoun R, El-Etr M 1999 Genomic and membrane actions of progesterone: implications for reproductive physiology and behavior. Behav Brain Res 105:37-52
18. Poindexter III AN, Dildy GA, Brody SA, Snabes MC, Brodyand SA 1993 The effects of a long-acting progestin on the hypothalamic-pituitary-ovarian axis in women with normal menstrual cycles. Contraception 48:37-45
19. Alexandris E, Milingos S, Kollios G, Seferiadis K, Lolis D, Messinis IE 1997 Changes in gonadotrophin response to gonadotrophin releasing hormone in normal women following bilateral ovariectomy. Clin Endocrinol (Oxf) 47:721-726
20. Goodman R, Karsch F 1980 Pulsatile secretion of luteinizing hormone: differential suppression by ovarian steroids. Endocrinology 107:1286-1290
21. O'Byrne K, Thalabard J, Grosser P, Wilson RC, Williams CL, Chen MD, Ladendorf D, Hotchkiss J, Knobil E 1991 Radiotelemetric monitoring of hypothalamic gonadotropin-releasing hormone pulse generator activity throughout the menstrual cycle of the rhesus monkey. Endocrinology 129:1207-1214
22. Karsch F, Cummins J, Thomas G, Clarke I 1987 Steroid feedback inhibition of pulsatile secretion of gonadotropin-releasing hormone in the ewe. Biol Reprod 36:1207-1218
23. Kasa-Vubu J, Dahl G, Evans N, Thrun LA, Moenter SM, Padmanabhan V, Karsch FJ 1992 Progesterone blocks the estradiol-induced gonadotropin discharge in the ewe by inhibiting the surge of gonadotropin-releasing hormone. Endocrinology 131:208-212
24. Scaramuzzi RJ, Tillson SA, Thorneycroft IH, Caldwell BV 1971 Action of exogenous progesterone and estrogen on behavioral estrus and luteinizing hormone levels in the ovariectomized ewe. Endocrinology 88:1184-1189
25. Souza C, Campbell B, Baird D 1997 Follicular dynamics and ovarian steroid secretion in sheep during the follicular and early luteal phases of the estrous cycle. Biol Reprod 56:483-488
26. Tsai MJ, O'Malley BW 1994 Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem 63:451-486
27. Horwitz K, Alexander P 1983 In situ photolinked nuclear progesterone receptors of human breast cancer cells: subunit molecular weights after transformation and translocation. Endocrinology 113:2195-2201
28. Vegeto E, Shahbaz M, Wen D, Goldman M, O'Malley B, McDonnell D 1993 Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. Mol Endocrinol 7:1244-1255
29. Sartorius C, Melville M, Hovland A, Tung L, Takimoto G, Horwitz K 1994 A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform. Mol Endocrinol 8:1347-1360
30. Kraus W, Weis K, Katzenellenbogen B 1995 Inhibitory cross-talk between steroid hormone receptors: differential targeting of estrogen receptor in the repression of its transcriptional activity by agonist- and antagonist-occupied progestin receptors. Mol Cell Biol 15:1847-1857
31. McDonnell D, Goldman M 1994 RU486 exerts antiestrogenic activities through a novel progesterone receptor A form-mediated mechanism. J Biol Chem 269:11945-11949
32. Ing NH, Beekman JM, Tsai SY, Tsai MJ, O'Malley BW 1992 Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II). J Biol Chem 267:17617-17623
33. Onate SA, Tsai SY, Tsai MJ, O'Malley BW 1995 Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354-1357
34. Smith CL, Onate SA, Tsai MJ, O'Malley BW 1996 CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription. Proc Natl Acad Sci USA 93:8884-8888
35. Cheng KW, Chow BKC, Leung PCK 2001 Functional mapping of a placenta-specific upstream promoter for human gonadotropin-releasing hormone receptor gene. Endocrinology 142:1506-1516
36. Han S, Sidell N 2003 RU486-induced growth inhibition of human endometrial cells involves the nuclear factor-κB signaling pathway. J Clin Endocrinol Metab 88:713-719
37. Christoffers AB, Kreisler M, Willershausen B 2003 Effects of estradiol and progesterone on the proliferation of human gingival fibroblasts. Eur J Med Res 8:535-542
38. Schumacher M, Guennoun R, Mercier G, Desarnaud F, Lacor P, Benavides J, Ferzaz B, Robert F, Baulieu EE 2001 Progesterone synthesis and myelin formation in peripheral nerves. Brain Res Brain Res Rev 37:343-359
39. Seeger H, Wallwiener D, Mueck AO 2003 The effect of progesterone and synthetic progestins on serum- and estradiol-stimulated proliferation of human breast cancer cells. Horm Metab Res 35:76-80
40. Nathwani PS, Rang SK, Cheng KW, Choi KC, Leung PC 2000 Regulation of gonadotropin-releasing hormone and its receptor gene expression by 17β-estradiol in cultured human granulosa-luteal cells. Endocrinology 141:1754-1763
41. Cheng KW, Cheng C-K, Leung PCK 2001 Differential role of PR-A and -B isoforms in transcription regulation of human GnRH receptor gene. Mol Endocrinol 15:2078-2092
42. Levine J 1997 New concepts of the neuroendocrine regulation of gonadotropin surges in rats. Biol Reprod 56:293-302
43. Herbison AE 1998 Multimodal influence of estrogen upon gonadotropin-releasing hormone neurons. Endocr Rev 19:302-330
44. Leipheimer R, Bona-Gallo A, Gallo R 1984 The influence of progesterone and estradiol on the acute changes in pulsatile luteinizing hormone release induced by ovariectomy on diestrous day 1 in the rat. Endocrinology 114:1605-1612
45. Skinner DC, Evans NP, Delaleu B, Goodman RL, Bouchard P, Caraty A 1998 The negative feedback actions of progesterone on gonadotropin-releasing hormone secretion are transduced by the classical progesterone receptor. Proc Natl Acad Sci USA 95:10978-10983
46. Hemmick LM, Ross ME, Evinger MJ 1995 Regulation of PNMT gene promoter constructs transfected into the TE 671 human medulloblastoma cell line. Neurosci Lett 201:77-80
47. Chen A, Zi K, Laskar-Levy O, Koch Y 2002 The transcription of the hGnRH-I and hGnRH-II genes in human neuronal cells is differentially regulated by estrogen. J Mol Neurosci 18:67-76
48. Truss M, Beato M 1993 Steroid hormone receptors: interaction with deoxyribonucleic acid and transcription factors. Endocr Rev 14:459-479
49. Wen D, Xu Y, Mais D, Goldman M, McDonnell D 1994 The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells. Mol Cell Biol 14:8356-8364
50. Baulieu E, Schumacher M 2000 Progesterone as a neuroactive neurosteroid, with special reference to the effect of progesterone on myelination. Steroids 65:605-612
51. Warner M, Gustafsson JA 1995 Cytochrome P450 in the brain: neuroendocrine functions. Front Neuroendocrinol 16:224-236
52. Chabbert-Buffeta N, Skinner DC, Caraty A, Bouchard P 2000 Neuroendocrine effects of progesterone. Steroids 65:613-620
53. Rosenblum PM, Goos HJ, Peter RE 1994 Regional distribution and in vitro secretion of salmon and chicken-II gonadotropin-releasing hormones from the brain and pituitary of juvenile and adult goldfish, Carassius auratus. Gen Comp Endocrinol 93:369-379
54. Sharp PJ, Talbot RT, Main GM, Dunn IC, Fraser HM, Huskisson NS 1990 Physiological roles of chicken LHRH-I and -II in the control of gonadotrophin release in the domestic chicken. J Endocrinol 124:291-299
55. Robinson JE, Healey AE, Harris TG, Messent EA, Skinner DC, Taylor JA, Evans NP 2000 The negative feedback action of progesterone on luteinizing hormone release is not associated with changes in GnRH mRNA expression in the Ewe. J Neuroendocrinol 12:121-129
56. Barni T, Maggi M, Fantoni G, Granchi S, Mancina R, Gulisano M, Marra F, Macorsini E, Luconi M, Rotella C, Serio M, Balboni GC, Vannelli GB 1999 Sex steroids and odorants modulate gonadotropin-releasing hormone secretion in primary cultures of human olfactory cells. J Clin Endocrinol Metab 84:4266-4273