Limited tumor-initiating activity of phenylethyl isothiocyanate by promotion with sodium L-ascorbate in a rat two-stage urinary bladder carcinogenesis model

Cancer Letters

Volumn 219, Issue 2, 2005, Pages 147-153

  Takagi, Hironori ^a,b   Shibutani, Makoto ^a,b   Uneyama, Chikako ^a   Lee, Kyoung Youl ^a   Kato, Natsumi ^a   Inoue, Kaoru ^a   Hirose, Masao ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

Initiation activity; Isothiocyanates; Phenylethyl isothiocyanate; Rat; Urinary bladder carcinogenesis

Indexed keywords

ASCORBIC ACID; ISOTHIOCYANIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CANCER; BLADDER CARCINOGENESIS; BLADDER CARCINOMA; CANCER INCIDENCE; CANCER STAGING; CONTROLLED STUDY; DIETARY INTAKE; DYSPLASIA; HYPERPLASIA; MALE; NODULAR HYPERPLASIA; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 13944274090     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2004.06.024     Document Type: Article

References (26)

1. S.S. Hecht Inhibition of carcinogenesis by isothiocyanates Drug Metab. Rev. 32 2000 395 411
2. MHLW (Ministry of Health, Labour and Welfare of Japan) List of existing food additives (Japanese) Foods Food Ingredients (Editorial) 166 1995 93 101
3. M.R. Spitz, C.M. Duphorne, M.A. Detry, P.C. Pillow, C.I. Amos, and L. Lei Dietary intake of isothiocyanates: evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk Cancer Epidemiol. Biomarkers Prev. 9 2000 1017 1020
4. B. Zhao, A. Seow, E.J.D. Lee, W.-T. Poh, M.I.P. Eng, and Y.-T. Wang Dietary isothiocyanates, glutathione S-transferase -M1, -T1 polymorphisms and lung cancer risk among Chinese woman in Singapore Cancer Epidemiol. Biomarkers Prev. 10 2001 1063 1067
5. F.-L. Chung, C.C. Conaway, C.V. Rao, and B.S. Reddy Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate Carcinogenesis 21 2000 2287 2291
6. G.D. Stoner, C. Adams, L.A. Kresty, S.G. Amin, D. Desai, and S.S. Hecht Inhibition of N′-nitrosonornicotine-induced esophageal tumorigenesis by 3-phenylpropyl isothiocyanate Carcinogenesis 19 1998 2139 2143
7. A. Nishikawa, F. Furukawa, C. Uneyama, S. Ikezaki, Z. Tanakamaru, and F.-L. Chung Chemopreventive effects of phenethyl isothiocyanate on lung and pancreatic tumorigenesis in N-nitrosobis(2-oxopropyl)amine-treated hamsters Carcinogenesis 17 1996 1381 1384
8. L.W. Wattenberg Inhibition of carcinogenic effects of polycyclic hydrocarbons by benzyl isothiocyanate and related compounds J. Natl Cancer Inst. 58 1977 395 398
9. G.D. Stoner, J.C. Siglin, M.A. Morse, D.H. Desai, S.G. Amin, and L.A. Kresty Enhancement of esophageal carcinogenesis in male F344 rats by dietary phenylhexyl isothiocyanate Carcinogenesis 16 1995 2473 2476
10. C.V. Rao, A. Rivenson, B. Simi, E. Zang, R. Hamid, and G.J. Kelloff Enhancement of experimental colon carcinogenesis by dietary 6-phenylhexyl isothiocyanate Cancer Res. 55 1995 4311 4318
11. M. Hirose, T. Yamaguchi, N. Kimoto, K. Ogawa, M. Futakuchi, M. Sano, and T. Shirai Strong promoting activity of phenylethyl isothiocyanate and benzyl isothiocyanate on urinary bladder carcinogenesis in F344 male rats Int. J. Cancer 77 1998 773 777
12. K. Ogawa, M. Futakuchi, M. Hirose, P. Boonyaphiphat, Y. Mizoguchi, T. Miki, and T. Shirai Stage and organ dependent effects of 1-O-hexyl-2,3,5- trimethylhydroquinone, ascorbic acid derivatives, n-heptadecane-8,10-dione and phenylethyl isothiocyanate in a rat multiorgan carcinogenesis model Int. J. Cancer 76 1998 851 856
13. R.A. Lubet, V.E. Steele, I. Eto, M.M. Juliana, G.J. Kelloff, and C.J. Grubbs Chemopreventive efficacy of anethole trithione, N-acetyl-l-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancer model Int. J. Cancer 72 1997 95 101
14. S. Sugiura, K. Ogawa, M. Hirose, F. Takeshita, M. Asamoto, and T. Shirai Reversibility of proliferative lesions and induction of non-papillary tumors in rat urinary bladder treated with phenylethyl isothiocyanate Carcinogenesis 24 2003 547 553
15. M. Kagawa, K. Hakoi, A. Yamamoto, M. Futakuchi, and M. Hirose Comparison of reversibility of rat forestomach lesions induced by genotoxic and non-genotoxic carcinogens Jpn. J. Cancer Res. 84 1993 1120 1129
16. F. Kassie, and S. Knasmüller Genotoxic effects of allyl isothiocyanate (AITC) and phenethyl isothiocyanate (PEITC) Chem. Biol. Interact. 127 2000 163 180
17. M. Murata, N. Yamashita, S. Inoue, and S. Kawanishi Mechanism of oxidative DNA damage induced by carcinogenic allyl isothiocyanate Free Radic. Biol. Med. 28 2000 797 805
18. F. Kassie, B. Pool-Zobel, W. Parzefall, and S. Knasmüller Genotoxic effects of benzyl isothiocyanate, a natural chemopreventive agent Mutagenesis 14 1999 595 604
19. R. Agarwal, Y. Shukla, S. Kumar, and N.K. Mehrotra Evaluation of carcinogenic effect of jute batching oil (JBO-P) fractions following topical application to mouse skin Arch. Toxicol. 62 1988 406 410
20. T. Umemura, Y. Kodama, K. Hioki, T. Nomura, A. Nishikawa, M. Hirose, and Y. Kurokawa The mouse rasH2/BHT model as an in vivo rapid assay for lung carcinogens Jpn. J. Cancer Res. 93 2002 861 866
21. S. Fukushima, H. Wanibuchi, K. Morimura, M. Wei, D. Nakae, and Y. Konishi Lack of initiation activity in rat liver of low doses of 2-amino-3,8- dimethylimidazo[4,5-f]quinoxaline Cancer Lett. 191 2003 35 40
22. S. Fukushima, K. Imaida, T. Sakata, T. Okamura, M. Shibata, and N. Ito Promoting effects of sodium l-ascorbate on two-stage urinary bladder carcinogenesis in rats Cancer Res. 43 1983 4454 4457
23. M. Wei, H. Wanibuchi, K. Morimura, S. Iwai, K. Yoshida, and G. Endo Carcinogenicity of dimethylarsinic acid in male F344 rats and genetic alterations in induced urinary bladder tumors Carcinogenesis 23 2002 1387 1397
24. G. Brüsewitz, B.D. Cameron, L.F. Chasseaud, K. Görler, D.R. Hawkins, H. Koch, and W.H. Mennicke The metabolism of benzyl isothiocyanate and its cysteine conjugate Biochem. J. 162 1977 99 107
25. M. Bollard, S. Stribbling, S. Mitchell, and J. Caldwell The disposition of allyl isothiocyanate in the rat and mouse Food Chem. Toxicol. 35 1997 933 943
26. N. Masutomi, K. Toyoda, M. Shibutani, N. Niho, C. Uneyama, N. Takahashi, and M. Hirose Toxic effects of benzyl and allyl isothiocyanates and benzyl-isoform specific metabolites in the urinary bladder after a single intravesical application to rats Toxicol. Pathol. 29 2001 617 622