Utilization of the genetic resources of wild species to create a nontransgenic high flavonoid tomato

Journal of Agricultural and Food Chemistry

Volumn 53, Issue 4, 2005, Pages 1231-1236

  Willits, Michael G ^a   Kramer, Catherine M ^a   Prata, Rogerio T N ^a   De Luca, Vincenzo ^a,b   Potter, Brian G ^a   Stephens, John C ^a   Graser, Gerson ^a  

^a SYNGENTA BIOTECHNOLOGY INC   (United States)

^b BROCK UNIVERSITY   (Canada)

Author keywords

Flavonoid; Lycopersicon esculentum; Lycopersicon pennellii; Natural products; Tomato

Indexed keywords

AGRONOMIC TRAIT; ARTICLE; BIOACCUMULATION; BIOSYNTHESIS; CONTROLLED STUDY; CROP; DIETARY INTAKE; DOMESTICATION; FOOD COMPOSITION; GENETIC ENGINEERING; GENETIC RESOURCE; GENETICALLY MODIFIED CROP; NONHUMAN; NORTHERN BLOTTING; PLANT BREEDING; PLANT GENETICS; TECHNIQUE; TOMATO; TRANSGENIC PLANT; WILD TYPE;

BREEDING; FLAVONOIDS; FRUIT; GENE EXPRESSION; GENETIC ENGINEERING; HYBRIDIZATION, GENETIC; LYCOPERSICON ESCULENTUM;

LYCOPERSICON ESCULENTUM; LYCOPERSICON PENNELLII;

EID: 13944260050     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf049355i     Document Type: Article

References (23)

1. Di Carlo, G.; Mascolo, N.; Izzo, A. A.; Capasso, F. Flavonoids: Old and new aspects of a class of natural therapeutic drugs. Life Sci. 1999, 65, 337-353.
2. Pietta, P. G. Flavonoids as antioxidants. J. Nat. Prod. 2000, 63, 1035-1042.
3. Harborne, J. B.; Williams, C. A. Advances in flavonoid research since 1992. Phytochemistry 2000, 55, 481-504.
4. Rice-Evans, C. A.; Miller, N. J.; Bolwell, P. G.; Bramley, P. M.; Pridham, J. B. The relative antioxidant activities of plant-derived polyphenolic flavonoids. Free Radical Res. 1995, 22, 375-383.
5. Rice-Evans, C. A.; Miller, N. J.; Paganga, G. Antioxidant properties of phenolic compounds. Trends Plant Sci. 1997, 2, 152-159.
6. Cook, N. C.; Samman, S. Flavonoids-Chemistry, metabolism, cardioprotective effects, and dietary sources. Nutr. Biochem. 1996, 7, 66-76.
7. Hollman, P. C. H.; Arts, I. C. W. Flavonols, flavones and flavanols - nature, occurrence and dietary burden. J. Sci. Food Agric. 2000, 80, 1081-1093.
8. Harborne, J. B. The Flavonoids, Advances in Research Since 1986; Chapman and Hall: London, 1994.
9. Hunt, G. M.; Baker, E. A. Phenolic constituents of tomato fruit cuticles. Phytochemistry 1980, 19, 1415-1419.
10. Muir, S. R.; Collins, G. J.; Robinson, S.; Hughes, S.; Bovy, A.; de Vos, C. H. R.; van Tunen, A. J.; Verhoeyen, M. E. Overexpression of petunia chalcone isomerase in tomato results in fruit containing increased levels of flavonols. Nat. Biotechnol. 2001, 19, 470-474.
11. Lagrimini, L. M.; Burkhart, W.; Moyer, M.; Rothstein, S. Molecular cloning of complementary DNA encoding the lignin-forming peroxidase from tobacco: molecular analysis and tissue-specific expression. Proc. Natl. Acad. Sci. U.S.A. 1987, 84, 7542-7546.
12. Stewart, A. J.; Bozonnet, S.; Mullen, W.; Jenkins, G. I.; Lean, M. E.; Crozier, A. Occurrence of flavonols in tomatoes and tomato-based products. J. Agric. Food Chem. 2000, 48, 2663-2669.
13. Martinez-Valverde, I.; Periago, M. J.; Provan, G.; Chesson, A. Phenolic compounds, lycopene and antioxidant activity in commercial varieties of tomato (Lycopersicon eculentum). J. Sci. Food Agric. 2002, 82, 323-330.
14. Colliver, S.; Bovy, A.; Collins, G.; Muir, S.; Robinson, S.; de Vos, C. H. R.; Verhoeyen, M. E. Improving the nutritional content of tomatoes through reprogramming their flavonoid biosynthetic pathway. Phytochem. Rev. 2002, 1, 113-123.
15. Hertog, M. G.; Hollman, P. C.; Katan, M. B. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in The Netherlands. J. Agric. Food Chem. 1992, 40, 2379-2383.
16. Price, K. R.; Bacon, J. B.; Rhodes, M. J. Effect of storage and domestic processing on the content and composition of flavonol glucosides in onion (Allium cepa). J. Agric. Food Chem. 1997, 45, 938-942.
17. Crozier, A.; Lean, M. E. J.; McDonald, M. S.; Black, C. Quantitative analysis of the flavonoid content of commercial tomatoes, onions, lettuce, and celery. J. Agric. Food Chem. 1997, 45, 590-595.
18. Eshed, Y.; Zamir, D. An introgression line population of Lycopersicon pennellii in the cultivated tomato enables the identification and fine mapping of yield-associated QTL. Genetics 1995, 141, 1147-1162.
19. van der Hoeven, R. S.; Monforte, A. J.; Breeden, D.; Tanksley, S. D.; Steffens, J. C. Genetic control and evolution of sesquiterpene biosynthesis in Lycopersicon esculentum and L. hirsutum. Plant Cell 2000, 12, 2283-2294.
20. Tadmor, Y.; Fridman, E.; Gur, A.; Larkov, O.; Lastochkin, E.; Ravid, U.; Zamir, D.; Lewinsohn, E. Identification of malodorous, a wild species allele affecting tomato aroma that was selected against during domestication. J. Agric. Food Chem. 2002, 50, 2005-2009.
21. van Noortlaan, O.; Hughes, S. G.; Muir, S. R.; van Tunen, A. J.; Verhoeyen, M. E.; De Vos, C. H. R. Methods and composition for modulating flavonoid content. International Patent #WO 99/37794, 1999.
22. Bovy, A.; de Vos, R.; Kemper, M.; Schijlen, E.; Pertejo, M. A.; Muir, S.; Collins, G.; Robinson, S.; Verhoeyen, M.; Hughes, S.; Santos-Buelga, C.; van Tunen, A. High-flavonol tomatoes resulting from the heterologous expression of the maize transcription factor genes LC and CI. Plant Cell 2002, 14, 2509-2526.
23. Tanksley, S. D.; McCouch, S. R. Seed banks and molecular maps: unlocking genetic potential from the wild. Science 1997, 277, 1063-1066.