-
1
-
-
1842685083
-
Thymidylate synthase as an oncogene: A novel role for an essential DNA synthesis enzyme
-
Rahman L, Voeller D, Rahman M, Lipkowitz S, Allegra C, Barrett JC, Kaye FJ, Zajac-Kaye M. Thymidylate synthase as an oncogene: A novel role for an essential DNA synthesis enzyme. Cancer Cell 2004; 5:341-51.
-
(2004)
Cancer Cell
, vol.5
, pp. 341-351
-
-
Rahman, L.1
Voeller, D.2
Rahman, M.3
Lipkowitz, S.4
Allegra, C.5
Barrett, J.C.6
Kaye, F.J.7
Zajac-Kaye, M.8
-
2
-
-
0028940399
-
Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
-
Johnston PG, Lenz HJ, Leichman CG, Danenberg KD, Allegra CJ, Danenberg PV, Leichman L. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 1995; 55:1407-12,
-
(1995)
Cancer Res
, vol.55
, pp. 1407-1412
-
-
Johnston, P.G.1
Lenz, H.J.2
Leichman, C.G.3
Danenberg, K.D.4
Allegra, C.J.5
Danenberg, P.V.6
Leichman, L.7
-
3
-
-
0030986625
-
Prognostic importance of thymidylate synthase expression in early breast cancer
-
Pestalozzi BC, Peterson HF, Gelber RD, Goldhirsch A, Gusterson BA, Trihia H, Lindtner J, Cortes-Funes H, Simmoncini E, Byrne MJ, Golouh R, Rudenstam CM, Castiglione-Gertsch M, Allegra CJ, Johnston PG. Prognostic importance of thymidylate synthase expression in early breast cancer. J Clin Oncol 1997; 15:1923-31.
-
(1997)
J Clin Oncol
, vol.15
, pp. 1923-1931
-
-
Pestalozzi, B.C.1
Peterson, H.F.2
Gelber, R.D.3
Goldhirsch, A.4
Gusterson, B.A.5
Trihia, H.6
Lindtner, J.7
Cortes-Funes, H.8
Simmoncini, E.9
Byrne, M.J.10
Golouh, R.11
Rudenstam, C.M.12
Castiglione-Gertsch, M.13
Allegra, C.J.14
Johnston, P.G.15
-
4
-
-
0033035738
-
Enhanced expression of thymidylate synthase may be of prognostic importance in advanced cervical cancer
-
Suzuki M, Tsukagoshi S, Saga Y, Ohwada M, Saro I. Enhanced expression of thymidylate synthase may be of prognostic importance in advanced cervical cancer. Oncology 1999; 57:50-4.
-
(1999)
Oncology
, vol.57
, pp. 50-54
-
-
Suzuki, M.1
Tsukagoshi, S.2
Saga, Y.3
Ohwada, M.4
Saro, I.5
-
5
-
-
0034949569
-
Predictive and prognostic markers in gastrointestinal cancers
-
Leichman CG. Predictive and prognostic markers in gastrointestinal cancers. Curr Opin Oncol 2001; 13:291-9.
-
(2001)
Curr Opin Oncol
, vol.13
, pp. 291-299
-
-
Leichman, C.G.1
-
6
-
-
0036038154
-
Clinical significance of thymidylate synthase expression in bladder cancer
-
Nomura T, Nakagawa M, Fujita Y, Hanada T, Mimata H, Nomura Y. Clinical significance of thymidylate synthase expression in bladder cancer. Int J Urol 2002; 9:368-76.
-
(2002)
Int J Urol
, vol.9
, pp. 368-376
-
-
Nomura, T.1
Nakagawa, M.2
Fujita, Y.3
Hanada, T.4
Mimata, H.5
Nomura, Y.6
-
7
-
-
0037386872
-
Significance of thymidylate synthase activity in renal cell carcinoma
-
Mizutani Y, Wada H, Yoshida O, Fukushima M, Nonomura M, Nakao M, Miki T. Significance of thymidylate synthase activity in renal cell carcinoma. Clin Cancer Res 2003; 9:1453-60.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1453-1460
-
-
Mizutani, Y.1
Wada, H.2
Yoshida, O.3
Fukushima, M.4
Nonomura, M.5
Nakao, M.6
Miki, T.7
-
8
-
-
0025990937
-
Auto regulation of human thymidylate synthase messenger RNA Translation by thymidylate synthase
-
Chu E, Koeller DM. Casey JL, Drake JC, Chabner BA, Elwood PC, Zinn S, Allegra CJ. Auto regulation of human thymidylate synthase messenger RNA Translation by thymidylate synthase. Proc Natl Acad Sci USA 1991; 88:8977-81.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 8977-8981
-
-
Chu, E.1
Koeller, D.M.2
Casey, J.L.3
Drake, J.C.4
Chabner, B.A.5
Elwood, P.C.6
Zinn, S.7
Allegra, C.J.8
-
9
-
-
0028924738
-
Thymidylare synthase binds to c-myc RNA in human colon cancer cells and in vitro
-
Chu E, Takechi T, Jones KL, Voeller DM, Copur SM, Maley GF, Maley F, Segal S, Allegra CJ. Thymidylare synthase binds to c-myc RNA in human colon cancer cells and in vitro. Mol Cell Biol 1995; 15:179-85.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 179-185
-
-
Chu, E.1
Takechi, T.2
Jones, K.L.3
Voeller, D.M.4
Copur, S.M.5
Maley, G.F.6
Maley, F.7
Segal, S.8
Allegra, C.J.9
-
10
-
-
0032929245
-
Thymidylate synthase protein and p53 mRNA form an in vivo ribonucleoprotein complex
-
Chu E, Copur SM, Ju J, Chen TM, Khleif S, Voeller DM, Mizunuma N, Patel M, Maley GF, Maley F, Allegra CJ. Thymidylate synthase protein and p53 mRNA form an in vivo ribonucleoprotein complex. Mol Cell Biol 1999; 19:1582-94.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1582-1594
-
-
Chu, E.1
Copur, S.M.2
Ju, J.3
Chen, T.M.4
Khleif, S.5
Voeller, D.M.6
Mizunuma, N.7
Patel, M.8
Maley, G.F.9
Maley, F.10
Allegra, C.J.11
-
11
-
-
1842685096
-
Thymidylare synthase as an oncogene?
-
Bertino JR, Banerjee D. Thymidylare synthase as an oncogene? Cancer Cell 2004; 5:301-2.
-
(2004)
Cancer Cell
, vol.5
, pp. 301-302
-
-
Bertino, J.R.1
Banerjee, D.2
-
13
-
-
0018148606
-
Mutagenicity of rhymidine to cultured Chinese hamster cells
-
Bradley MO, Sharkey NA. Mutagenicity of rhymidine to cultured Chinese hamster cells. Nature 1978; 274:607-8.
-
(1978)
Nature
, vol.274
, pp. 607-608
-
-
Bradley, M.O.1
Sharkey, N.A.2
-
14
-
-
0019488988
-
Sensitivity of a mutator gene in Chinese hamster ovary cell to deoxynucleoside triphosphate pool alterations
-
Meuth M. Sensitivity of a mutator gene in Chinese hamster ovary cell to deoxynucleoside triphosphate pool alterations. Mol Cell Biol 1981; 1:652-60.
-
(1981)
Mol Cell Biol
, vol.1
, pp. 652-660
-
-
Meuth, M.1
-
15
-
-
0024505072
-
The molecular basis of mutations induced by deoxyribonucleoside triphosphate pool imbalances in mammalian cells
-
Meuth M. The molecular basis of mutations induced by deoxyribonucleoside triphosphate pool imbalances in mammalian cells. Exp Cell Res 1989; 181:305-16.
-
(1989)
Exp Cell Res
, vol.181
, pp. 305-316
-
-
Meuth, M.1
-
16
-
-
0346106146
-
Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication
-
Angus SP, Wheeler LJ, Ranmal SA, Zhang X, Markey MP, Mathews CK, Knudsen ES. Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication. J Biol Chem 2002; 277:44376-84.
-
(2002)
J Biol Chem
, vol.277
, pp. 44376-44384
-
-
Angus, S.P.1
Wheeler, L.J.2
Ranmal, S.A.3
Zhang, X.4
Markey, M.P.5
Mathews, C.K.6
Knudsen, E.S.7
-
17
-
-
0031886093
-
Regulation of cell proliferation by the E2F transcription factors
-
Helin K. Regulation of cell proliferation by the E2F transcription factors. Curr Opin Genet Dev 1998; 8:28-35.
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 28-35
-
-
Helin, K.1
-
18
-
-
0032146274
-
The regulation of E2F by pRB-family proteins
-
Dyson N. The regulation of E2F by pRB-family proteins. Genes Dev 1998; 12:2245-62.
-
(1998)
Genes Dev
, vol.12
, pp. 2245-2262
-
-
Dyson, N.1
-
19
-
-
0034306996
-
The Rb/E2F pathway: Expanding roles and emerging paradigms
-
Harbour JW, Dean DC. The Rb/E2F pathway: Expanding roles and emerging paradigms. Genes Dev 2000; 14:2393-409.
-
(2000)
Genes Dev
, vol.14
, pp. 2393-2409
-
-
Harbour, J.W.1
Dean, D.C.2
-
20
-
-
0030332123
-
Mechanisms of clinical resistance to 5-fluorouracil chemotherapy
-
Chu E, Allegra CJ. Mechanisms of clinical resistance to 5-fluorouracil chemotherapy. Cancer Treat Res 1996; 87:175-95.
-
(1996)
Cancer Treat Res
, vol.87
, pp. 175-195
-
-
Chu, E.1
Allegra, C.J.2
-
21
-
-
12144290775
-
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients
-
Wang TL, Diaz LA Jr, Romans K, Bardelli A, Saha S, Galizia G, Choti M, Donehower R, Parmigiani G, Shih IeM, Iacobuzio-Donahue C, Kinder KW, Vogelsrein B, Lengauer C, Velculescu VE. Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients. Proc Natl Acad Sci USA 2004; 101:3089-94.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3089-3094
-
-
Wang, T.L.1
Diaz Jr., L.A.2
Romans, K.3
Bardelli, A.4
Saha, S.5
Galizia, G.6
Choti, M.7
Donehower, R.8
Parmigiani, G.9
Shih, Ie.M.10
Iacobuzio-Donahue, C.11
Kinder, K.W.12
Vogelsrein, B.13
Lengauer, C.14
Velculescu, V.E.15
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