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Volumn 43, Issue 2, 2005, Pages 13-16

Antiepileptics, pregnancy and the child
[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; ETIRACETAM; FOLIC ACID; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PREGABALIN; PRIMIDONE; TOPIRAMATE; VALPROIC ACID; VITAMIN K GROUP;

EID: 13844309396     PISSN: 00126543     EISSN: None     Source Type: Journal    
DOI: 10.1136/dtb.2005.43213     Document Type: Review
Times cited : (8)

References (62)
  • 1
    • 0034675309 scopus 로고    scopus 로고
    • Population based, prospective study of the care of women with epilepsy in pregnancy
    • Fairgrieve SD et al. Population based, prospective study of the care of women with epilepsy in pregnancy. BMJ 2000; 321: 674-5.
    • (2000) BMJ , vol.321 , pp. 674-675
    • Fairgrieve, S.D.1
  • 3
    • 0028200615 scopus 로고
    • Epilepsy and pregnancy
    • Epilepsy and pregnancy. DTB 1994; 32: 49-51.
    • (1994) DTB , vol.32 , pp. 49-51
  • 4
    • 0035133563 scopus 로고    scopus 로고
    • Additional educational needs in children born to mothers with epilepsy
    • Adab N et al. Additional educational needs in children born to mothers with epilepsy. J Neurol Neurosurg Psychiatry 2001; 70: 15-21.
    • (2001) J. Neurol. Neurosurg. Psychiatry , vol.70 , pp. 15-21
    • Adab, N.1
  • 5
    • 0026847483 scopus 로고
    • Minor anomalies in children of mothers with epilepsy
    • Gaily E, Granström M-L. Minor anomalies in children of mothers with epilepsy. Neurology 1992; 42 (suppl 5): 128-31.
    • (1992) Neurology , vol.42 , Issue.SUPPL. 5 , pp. 128-131
    • Gaily, E.1    Granström, M.-L.2
  • 7
    • 0023156494 scopus 로고
    • Anticonvulsants, folate levels, and pregnancy outcome: A prospective study
    • Dansky LV et al. Anticonvulsants, folate levels, and pregnancy outcome: a prospective study. Ann Neurol 1987; 21: 176-82.
    • (1987) Ann. Neurol. , vol.21 , pp. 176-182
    • Dansky, L.V.1
  • 8
    • 0025863475 scopus 로고
    • Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study
    • MRC Vitamin Study Research Group
    • MRC Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 1991; 338: 131-7.
    • (1991) Lancet , vol.338 , pp. 131-137
  • 9
    • 0027080461 scopus 로고
    • Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation
    • Czeizel AE, Dudás I. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 1992; 327: 1832-5.
    • (1992) N. Engl. J. Med. , vol.327 , pp. 1832-1835
    • Czeizel, A.E.1    Dudás, I.2
  • 10
    • 10444284584 scopus 로고    scopus 로고
    • Joint Formulary Committee. Edition 48. London: Royal Pharmaceutical Society of Great Britain and British Medical Association, September
    • Joint Formulary Committee. British National Formulary. Edition 48. London: Royal Pharmaceutical Society of Great Britain and British Medical Association, September 2004.
    • (2004) British National Formulary
  • 11
    • 24944456514 scopus 로고    scopus 로고
    • The epilepsies: The diagnosis and management of the epilepsies in adults and children in primary and secondary care
    • National Institute for Clinical Excellence, [online] Available: [Accessed 13 January 2005]
    • National Institute for Clinical Excellence, 2004. The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care [online]. Available: http://www.nice.org.uk/pdf/CG020NICEguideline.pdf [Accessed 13 January 2005].
    • (2004)
  • 12
    • 0033822097 scopus 로고    scopus 로고
    • Quality of life, epilepsy advances, and the evolving role of anticonvulsants in women with epilepsy
    • Yerby MS. Quality of life, epilepsy advances, and the evolving role of anticonvulsants in women with epilepsy. Neurology 2000; 55 (suppl 1): S21-31.
    • (2000) Neurology , vol.55 , Issue.SUPPL. 1
    • Yerby, M.S.1
  • 13
    • 1342302925 scopus 로고    scopus 로고
    • Epilepsy and pregnancy: An obstetric perspective
    • Richmond JR et al. Epilepsy and pregnancy: an obstetric perspective. Am J Obstet Gynecol 2004; 190: 371-9.
    • (2004) Am. J. Obstet. Gynecol. , vol.190 , pp. 371-379
    • Richmond, J.R.1
  • 14
    • 0023005470 scopus 로고
    • Evaluation of drug therapy and teratogenic risk in a Rhône-Alpes district population of pregnant epileptic women
    • Robert E et al. Evaluation of drug therapy and teratogenic risk in a Rhône-Alpes district population of pregnant epileptic women. Eur Neurol 1986; 25: 436-43.
    • (1986) Eur. Neurol. , vol.25 , pp. 436-443
    • Robert, E.1
  • 15
    • 1542315305 scopus 로고    scopus 로고
    • Malformation rates in children of women with untreated epilepsy. A meta-analysis
    • Fried S et al. Malformation rates in children of women with untreated epilepsy. A meta-analysis. Drug Saf 2004; 27: 197-202.
    • (2004) Drug Saf. , vol.27 , pp. 197-202
    • Fried, S.1
  • 16
    • 1242314854 scopus 로고    scopus 로고
    • Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: A nation-wide, population-based register study
    • Wide K et al. Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study. Acta Paediatr 2004; 93: 174-6.
    • (2004) Acta Paediatr. , vol.93 , pp. 174-176
    • Wide, K.1
  • 17
    • 0036799783 scopus 로고    scopus 로고
    • Preliminary results on pregnancy outcomes in women using lamotrigine
    • Tennis P et al. Preliminary results on pregnancy outcomes in women using lamotrigine. Epilepsia 2002; 43: 1161-7.
    • (2002) Epilepsia , vol.43 , pp. 1161-1167
    • Tennis, P.1
  • 18
    • 0036010428 scopus 로고    scopus 로고
    • The teratogenic effect of carbamazepine: A meta-analysis of 1255 exposures
    • Matalon S et al. The teratogenic effect of carbamazepine: a meta-analysis of 1255 exposures. Reprod Toxicol 2002; 16: 9-17.
    • (2002) Reprod. Toxicol. , vol.16 , pp. 9-17
    • Matalon, S.1
  • 19
    • 14444288534 scopus 로고    scopus 로고
    • Maternal use of antiepileptic drugs and the risk of major congenital malformations: A joint European prospective study of human teratogenesis associated with maternal epilepsy
    • Samrén EB et al. Maternal use of antiepileptic drugs and the risk of major congenital malformations: a joint European prospective study of human teratogenesis associated with maternal epilepsy. Epilepsia 1997; 38: 981-90.
    • (1997) Epilepsia , vol.38 , pp. 981-990
    • Samrén, E.B.1
  • 20
    • 0033766475 scopus 로고    scopus 로고
    • Teratogenic effects of antiepileptic drugs: Use of an international database on malformations and drug exposure (MADRE)
    • Arpino C et al. Teratogenic effects of antiepileptic drugs: use of an international database on malformations and drug exposure (MADRE). Epilepsia 2000; 41: 1436-43.
    • (2000) Epilepsia , vol.41 , pp. 1436-1443
    • Arpino, C.1
  • 21
    • 0141670265 scopus 로고    scopus 로고
    • The Australian registry of anti-epileptic drugs in pregnancy: Experience after 30 months
    • Vajda FJ et al. The Australian registry of anti-epileptic drugs in pregnancy: experience after 30 months. J Clin Neurosci 2003; 10: 543-9.
    • (2003) J. Clin. Neurosci. , vol.10 , pp. 543-549
    • Vajda, F.J.1
  • 22
    • 0032747235 scopus 로고    scopus 로고
    • Antiepileptic drug regimens and major congenital abnormalities in the offspring
    • Samrén EB et al. Antiepileptic drug regimens and major congenital abnormalities in the offspring. Ann Neurol 1999; 46: 739-46.
    • (1999) Ann. Neurol. , vol.46 , pp. 739-746
    • Samrén, E.B.1
  • 23
    • 0033066533 scopus 로고    scopus 로고
    • Congenital malformations due to antiepileptic drugs
    • Kaneko S et al. Congenital malformations due to antiepileptic drugs. Epilepsy Res 1999; 33: 145-58.
    • (1999) Epilepsy Res. , vol.33 , pp. 145-158
    • Kaneko, S.1
  • 24
    • 13844320943 scopus 로고    scopus 로고
    • The UK epilepsy and pregnancy register: Update of results 1996-2003
    • [abstract 2.112]
    • Craig J et al. The UK epilepsy and pregnancy register: update of results 1996-2003. Epilepsia 2004; 45 (suppl 7): 229 [abstract 2.112].
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 7 , pp. 229
    • Craig, J.1
  • 25
    • 0035849144 scopus 로고    scopus 로고
    • The teratogenicity of anticonvulsant drugs
    • Holmes LB et al. The teratogenicity of anticonvulsant drugs. N Engl J Med 2001; 344: 1132-8.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1132-1138
    • Holmes, L.B.1
  • 26
    • 0032869050 scopus 로고    scopus 로고
    • Malformations in offspring of women with epilepsy: A prospective study
    • Canger R et al. Malformations in offspring of women with epilepsy: a prospective study. Epilepsia 1999; 40: 1231-6.
    • (1999) Epilepsia , vol.40 , pp. 1231-1236
    • Canger, R.1
  • 27
    • 2442554134 scopus 로고    scopus 로고
    • The AED (antiepileptic drug) pregnancy registry. A 6-year experience
    • Holmes LB et al. The AED (antiepileptic drug) pregnancy registry. A 6-year experience. Arch Neurol 2004; 61: 673-8.
    • (2004) Arch. Neurol. , vol.61 , pp. 673-678
    • Holmes, L.B.1
  • 28
    • 1842788174 scopus 로고    scopus 로고
    • Oxcarbazepine in pregnancy: Clinical experience in Argentina
    • Meischenguiser R et al. Oxcarbazepine in pregnancy: clinical experience in Argentina. Epilepsy Behav 2004; 5: 163-7.
    • (2004) Epilepsy Behav. , vol.5 , pp. 163-167
    • Meischenguiser, R.1
  • 29
    • 0037465533 scopus 로고    scopus 로고
    • Major malformations in offspring of women with epilepsy
    • Kaaja E et al. Major malformations in offspring of women with epilepsy. Neurology 2003; 60: 575-9.
    • (2003) Neurology , vol.60 , pp. 575-579
    • Kaaja, E.1
  • 30
    • 0037974463 scopus 로고    scopus 로고
    • Clinical care of pregnant women with epilepsy: Neural tube defects and folic acid supplementation
    • Yerby MS. Clinical care of pregnant women with epilepsy: neural tube defects and folic acid supplementation. Epilepsia 2003; 44 (suppl 3): 33-40.
    • (2003) Epilepsia , vol.44 , Issue.SUPPL. 3 , pp. 33-40
    • Yerby, M.S.1
  • 31
    • 0036712989 scopus 로고    scopus 로고
    • A postmarketing surveillance study of gabapentin as add-on therapy for 3,100 patients in England
    • Wilton LV, Shakir S. A postmarketing surveillance study of gabapentin as add-on therapy for 3,100 patients in England. Epilepsia 2002; 43: 983-92.
    • (2002) Epilepsia , vol.43 , pp. 983-992
    • Wilton, L.V.1    Shakir, S.2
  • 32
    • 0141706894 scopus 로고    scopus 로고
    • Gabapentin exposure in human pregnancy: Results from the gabapentin pregnancy registry
    • Montouris G. Gabapentin exposure in human pregnancy: results from the gabapentin pregnancy registry. Epilepsy Behav 2003; 4: 310-7.
    • (2003) Epilepsy Behav. , vol.4 , pp. 310-317
    • Montouris, G.1
  • 33
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Janssen-Cilag Limited, August Topamax tablets and sprinkle
    • Topamax tablets and sprinkle. Summary of product characteristics, UK. Janssen-Cilag Limited, August 2004.
    • (2004)
  • 34
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, Belgium
    • UCB S.A, July Keppra
    • Keppra. Summary of product characteristics, Belgium. UCB S.A, July 2004.
    • (2004)
  • 35
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Pfizer Limited, September Lyrica capsules
    • Lyrica capsules. Summary of product characteristics, UK. Pfizer Limited, September 2004.
    • (2004)
  • 36
    • 0023888786 scopus 로고
    • Minor anomalies in offspring of epileptic mothers
    • Gaily E et al. Minor anomalies in offspring of epileptic mothers. J Pediatr 1988; 112: 520-9.
    • (1988) J. Pediatr. , vol.112 , pp. 520-529
    • Gaily, E.1
  • 37
    • 0034496704 scopus 로고    scopus 로고
    • Birth weight in offspring of women with epilepsy
    • Hvas CL et al. Birth weight in offspring of women with epilepsy. Epidemiol Rev 2000; 22: 275-82.
    • (2000) Epidemiol. Rev. , vol.22 , pp. 275-282
    • Hvas, C.L.1
  • 38
    • 0033922409 scopus 로고    scopus 로고
    • Body dimensions of infants exposed to antiepileptic drugs in utero: Observations spanning 25 years
    • Wide K et al. Body dimensions of infants exposed to antiepileptic drugs in utero: observations spanning 25 years. Epilepsia 2000; 41: 854-61.
    • (2000) Epilepsia , vol.41 , pp. 854-861
    • Wide, K.1
  • 39
    • 0142078725 scopus 로고    scopus 로고
    • Scottish Intercollegiate Guidelines Network [online] Available: [Accessed 13 January 2005]
    • Scottish Intercollegiate Guidelines Network, 2003. Diagnosis and management of epilepsy in adults. A national clinical guideline [online]. Available: http://www.sign.ac.uk/pdf/sign70.pdf [Accessed 13 January 2005].
    • (2003) Diagnosis and Management of Epilepsy in Adults. A National Clinical Guideline
  • 40
    • 0036257073 scopus 로고    scopus 로고
    • Long term health and neurodevelopment in children exposed to antiepileptic drugs before birth
    • Dean JC et al. Long term health and neurodevelopment in children exposed to antiepileptic drugs before birth. J Med Genet 2002; 39: 251-9.
    • (2002) J. Med. Genet. , vol.39 , pp. 251-259
    • Dean, J.C.1
  • 41
    • 2342439978 scopus 로고    scopus 로고
    • Belgian consensus on recommendations for standards of care for women with epilepsy before, during and after pregnancy
    • Boon P et al. Belgian consensus on recommendations for standards of care for women with epilepsy before, during and after pregnancy. Acta Neurol Belg 2004; 104: 6-12.
    • (2004) Acta Neurol. Belg. , vol.104 , pp. 6-12
    • Boon, P.1
  • 42
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Aventis Pharma Ltd, January Frisium tablets 10mg
    • Frisium tablets 10mg. Summary of product characteristics, UK. Aventis Pharma Ltd, January 2002.
    • (2002)
  • 43
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Roche Products Limited, March Rivotril tablets
    • Rivotril tablets. Summary of product characteristics, UK. Roche Products Limited, March 2002.
    • (2002)
  • 44
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Novartis Pharmaceuticals UK Limited, May Trileptal 150, 300, 600
    • Trileptal 150, 300, 600. Summary of product characteristics, UK. Novartis Pharmaceuticals UK Limited, May 2002.
    • (2002)
  • 45
    • 13844322319 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Pfizer Limited, June Zarontin syrup and capsules
    • Zarontin syrup and capsules. Summary of product characteristics, UK. Pfizer Limited, June 2003.
    • (2003)
  • 46
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Pfizer Limited, March Epanutin capsules 25, 50, 100 and 300mg
    • Epanutin capsules 25, 50, 100 and 300mg. Summary of product characteristics, UK. Pfizer Limited, March 2004.
    • (2004)
  • 47
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Gabitril 5mg, gabitril 10mg, gabithl 15mg. Cephalon UK Limited, November
    • Gabitril 5mg, gabitril 10mg, gabithl 15mg. Summary of product characteristics, UK. Cephalon UK Limited, November 2003.
    • (2003)
  • 48
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Aventis Pharma Limited, May Sabril sachets 0.5g and tablets 500mg
    • Sabril sachets 0.5g and tablets 500mg. Summary of product characteristics, UK. Aventis Pharma Limited, May 2004.
    • (2004)
  • 49
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • UCB Pharma Ltd, March Nootropil tablets 800mg, 1200mg, solution 33%
    • Nootropil tablets 800mg, 1200mg, solution 33%. Summary of product characteristics, UK. UCB Pharma Ltd, March 2000.
    • (2000)
  • 50
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Wamer Lambert, January Neurontin
    • Neurontin. Summary of product characteristics, UK Wamer Lambert, January 2004.
    • (2004)
  • 51
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • The Wellcome Foundation Ltd, September Lamictal combined tablets
    • Lamictal combined tablets. Summary of product characteristics, UK. The Wellcome Foundation Ltd, September 2003.
    • (2003)
  • 52
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Cyanamid of Great Britain Limited, February Diamox sodium parenteral 500mg/vial
    • Diamox sodium parenteral 500mg/vial. Summary of product characteristics, UK. Cyanamid of Great Britain Limited, February 2004.
    • (2004)
  • 53
    • 7244257375 scopus 로고    scopus 로고
    • The longer term outcome of children born to mothers with epilepsy
    • Adab N et al. The longer term outcome of children born to mothers with epilepsy. J Neurol Neurosurg Psychiatry 2004; 75: 1575-83.
    • (2004) J. Neurol. Neurosurg. Psychiatry , vol.75 , pp. 1575-1583
    • Adab, N.1
  • 54
    • 0025296135 scopus 로고
    • Specific cognitive dysfunction in children with epileptic mothers
    • Gaily E et al. Specific cognitive dysfunction in children with epileptic mothers. Dev Med Child Neurol 1990; 32: 403-14.
    • (1990) Dev. Med. Child Neurol. , vol.32 , pp. 403-414
    • Gaily, E.1
  • 55
    • 0023803288 scopus 로고
    • Intelligence of children of epileptic mothers
    • Gaily E et al. Intelligence of children of epileptic mothers. J Pediatr 1988; 113:677-84.
    • (1988) J. Pediatr , vol.113 , pp. 677-684
    • Gaily, E.1
  • 56
    • 0030299983 scopus 로고    scopus 로고
    • Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy
    • Ornoy A, Cohen E. Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy. Arch Dis Child 1996; 75: 517-20.
    • (1996) Arch. Dis. Child , vol.75 , pp. 517-520
    • Ornoy, A.1    Cohen, E.2
  • 57
    • 0028197242 scopus 로고
    • Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy
    • Scolnik D et al. Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy. JAMA 1994; 271: 767-70.
    • (1994) JAMA , vol.271 , pp. 767-770
    • Scolnik, D.1
  • 58
    • 9144257236 scopus 로고    scopus 로고
    • Normal intelligence in children with prenatal exposure to carbamazepine
    • Gaily E et al. Normal intelligence in children with prenatal exposure to carbamazepine. Neurology 2004; 62: 28-32.
    • (2004) Neurology , vol.62 , pp. 28-32
    • Gaily, E.1
  • 59
    • 0041825828 scopus 로고    scopus 로고
    • When and how to stop antiepileptic drugs in adults
    • When and how to stop antiepileptic drugs in adults. DTB 2003; 41: 41-3.
    • (2003) DTB , vol.41 , pp. 41-43
  • 60
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Sanofi-Synthelabo, March Epilim
    • Epilim. Summary of product characteristics, UK. Sanofi-Synthelabo, March 2004.
    • (2004)
  • 61
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • Novartis Pharmaceuticals UK Limited, January Tegretol chewtabs 100mg, 200mg,Tegretol tablets 100mg, 200mg, 400mg
    • Tegretol chewtabs 100mg, 200mg,Tegretol tablets 100mg, 200mg, 400mg. Summary of product characteristics, UK. Novartis Pharmaceuticals UK Limited, January 2003.
    • (2003)
  • 62
    • 0003443998 scopus 로고    scopus 로고
    • Summary of product characteristics, UK
    • AstraZeneca UK Limited, November Mysoline tablets
    • Mysoline tablets. Summary of product characteristics, UK. AstraZeneca UK Limited, November 2003.
    • (2003)


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