Over-expressed IgG2 antibodies against O-acetylated sialoglycoconjugates incapable of proper effector functioning in childhood acute lymphoblastic leukemia

International Immunology

Volumn 17, Issue 2, 2005, Pages 177-191

  Bandyopadhyay, Suman ^a   Bhattacharyya, Arindam ^b   Mallick, Asish ^a   Sen, Asish Kumar ^a   Tripathi, Gayatri ^a   Das, Tanya ^b   Sa, Gaurisankar ^b   Bhattacharya, Dilip Kumar ^c   Mandal, Chitra ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b BOSE INSTITUTE   (India)

^c VIVEKANANDA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Anti 9 OAcSGs; Effector function; Glycosylation; Subclass

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G2; N ACETYLGALACTOSAMINE; SIALIC ACID DERIVATIVE; SIALOGLYCOPROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; BLOOD SAMPLING; CELL MEDIATED CYTOTOXICITY; CHILD; CLINICAL ARTICLE; COMPLEMENT FIXATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EFFECTOR CELL; ENZYME ASSAY; FEMALE; FLOW CYTOMETRY; GAS LIQUID CHROMATOGRAPHY; HEMAGGLUTINATION; HUMAN; HUMAN CELL; IMMUNOSURVEILLANCE; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; MALE; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

CHILD; CYTOTOXICITY, IMMUNOLOGIC; GLYCOCONJUGATES; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN G; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; RECEPTORS, FC; SIALIC ACIDS;

EID: 13844294379     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxh198     Document Type: Article

References (52)

1. Pui, C. H., Campana, D. and Evans, W. E. 2001. Childhood acute lymphoblastic leukemia - current status and future perspectives. Lancet Oncol. 2:597.
2. Bjorklund, E., Majur, J., Soderhall, S. and Porwit-MacDonald, A. 2003. Flow cytometric follow-up of minimal residual disease in bone marrow gives prognostic information in children with acute lymphoblastic leukemia. Leukemia 17:138.
3. Mandal, C., Chatterjee, M. and Sinha, D. 2000. Investigation of 9-O-acetylated sialoglycoconjugates in childhood acute lymphoblastic leukemia. Br. J. Haematol. 110:801.
4. Kelm, S. and Schauer, R. 1997. Sialic acids in molecular and cellular interactions. Int. Rev Cytol. 175:137.
5. Klein, A. and Roussel, P. 1998. O-Acetylation of sialic acids. Biochimie 80:49.
6. Angata, T. and Varki, A. 2002. Chemical diversity in the sialic acids and related alpha-keto acids: an evolutionary perspective. Chem. Rev. 102:439.
7. Sinha, D., Chatterjee, M. and Mandal, C. 2000. O Acetylated sialic acids - their detection, biological significance and alteration in diseases. Trends Glycosci. Glycotechnol. 12:17.
8. H, a sialic-acid binding lectin from Achatina fulica. Carbohydr. Res. 268:115.
9. H from the hemolymph of Achatina fulica snail. Biochem. Biophys. Res. Commun. 148:795.
10. Basu, S., Mandal, C. and Allen, A. K. 1988. Chemical-modification studies of a unique sialic acid binding lectin from the snail Achatina fulica. Biochem. J. 254:195.
11. Mandal, C., Basu, S. and Mandal, C. 1989. Physicochemical studies on AchatininH, a novel sialic acid binding lectin. Biochem. J. 257:65.
12. H, as a probe. Leukemia 13:119.
13. Pal, S., Ghosh, S., Mandal, C. et al. 2004. Purification and characterization of 9-O-acetylated sialoglycoproteins from leukemic cells and their potential as immunological tool for monitoring childhood acute lymphoblastic leukemia. Glycobiology 14:859.
14. Pal, S., Chatterjee, M., Bhattacharya, D. K., Bandhyopadhyay, S., Mandal, C. and Mandal, C. 2001. O-acetyl sialic acid specific IgM as a diagnostic marker in childhood acute lymphoblastic leukemia. Glycoconj. J. 18:529.
15. Pal, S., Chatterjee, M., Bhattacharya, D. K., Bandhyopadhyay, S. and Mandal, C. 2000. Identification and purification of cytolytic antibodies directed against O-acetylated sialic acid in childhood acute lymphoblastic leukemia. Glycobiology 10:539.
16. Pal, S., Bandyopadhyay, S., Chatterjee, M. et al. 2004. Antibodies against 9-O-acetylated sialoglycans: a potent marker to monitor clinical status in childhood acute lymphoblastic leukemia. Clin. Biochem. 37:395.
17. Bandyopadhyay, S., Mukherjee, K., Chatterjee, M., Bhattacharya, D. K. and Mandal, C. 2004. Detection of immune-complexed 9-O-acetylated sialoglycoconjugates in the sera of patients with pediatric acute lymphoblastic leukemia (ALL). J. Immunol. Methods. in press.
18. Dunn, G. P., Bruce, A. T., Ikeda, H., Old, L. J. and Schreiber, R. D. 2002. Cancer immunoediting: from immunosurveillance to tumor escape. Nat. Immunol. 3:991.
19. Khong, H. T. and Restifo, N. P. 2002. Natural selection of tumor variants in the generation of "tumor escape" phenotypes. Nat. Immunol. 3:999.
20. Takeda, K., Smyth, M. J., Cretney, E. et al. 2002. Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development. J. Exp. Med. 195:161.
21. Catlett-Falcone, R., Landowski, T. H., Oshiro, M. M. et al. 1999. Constitutive activation of stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 10:105.
22. Marincola, F. M., Jaffee, E. M., Hicklin, D. J. and Ferrone, S. 2000. Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv. Immunol. 74:181.
23. Kaplan, D. H., Shankaran, V., Dighe, A. S. et al. 1998. Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice. Proc. Natl Acad. Sci. USA 95:7556.
24. Burns, C. P., Armitage, J. O., Frey, A. L., Dick, F. R., Jordan, J. E. and Woolson, R. F. 1981. Analysis of the presenting features of adult acute leukemias: the French-American-British classification. Cancer 47:2460.
25. Murphy, W. H. and Gottschalk, A. 1961. Studies on mucoproteins, VII. The linkage of the prosthetic group to aspartic and glutamic acid residues in bovine submaxillary gland mucoprotein. Biochim. Biophys. Acta 52:349.
26. Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. 1951. Protein measurement with folin phenol reagent. J. Biol. Chem. 193:265.
27. Chatterjee, M., Chava, A. K., Kohla, G. et al. 2003. Identification and characterization of adsorbed serum sialoglycans on Leishmania donovani promastigotes. Glycobiology 13:351.
28. Shukla, A. K. and Schauer, R. 1982. Fluorimetric determination of unsubstituted and 9(8)-O-acetylated sialic acids in erythrocyte membranes. Hoppe-Seyler's Z. Physiol. Chem. 363:255.
29. Kohn, J. and Wilchek, M. 1982. A new approach (cyano-transfer) for cyanogen bromide activation of sepharose at neutral pH, which yields activated resin, free of interfering nitrogen derivatives. Biochem. Biophys. Res. Commun. 107:878.
30. Reuter, G., Pfeil, R., Stoll S. et al. 1983. Identification of new sialic acids derived from glycoprotein of bovine submandibular gland. Eur. J. Biochem. 134:139.
31. Laemmli, U. K. and Favre, M. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680.
32. Coligan, E. J., Kruisbeek, M. A., Margulies, H. D., Shevach, M. E. and Strober, W. 1993. Labeling antibody with fluorescein isothiocyanate (FITC). In Coligan, E. J., Kruisbeek, M. A., Margulies, H. D., Shevach, M. E. and Strober, W., eds, Current Protocols in Immunology. National Institutes of Health, vol. 1, p. 5.3.2. John Wiley & Sons, New York, USA.
33. Pal, S., Ghosh, S., Bandyopadhyay, S. et al. 2004. Differential expression of 9-O-acetylated sialoglycoconjugates on leukemic blasts: a potential tool for long-term monitoring of children with acute lymphoblastic leukemia. Int. J. Cancer, 111:270.
34. Sloneker, J. H. 1972. Gas-liquid chromatography of alditol acetates. In Whistler, R. L. and BeMiller, J. N., eds, Methods in Carbohydrate Chemistry, VI, p. 20. Academic Press Inc., New York.
35. Hunter, W. M. 1978. In Weir, D. M., ed., Handbook of Experimental Medicine, p. 14.1. Blackwell Scientific, London.
36. Dominguez, M., Moreno, I., Lopez-Trascasa, M. and Torano, A. 2002. Complement interaction with trypanosomatid promastigotes in normal human serum. J. Exp. Med. 195:451.
37. Coligan, E. J., Kruisbeek, M. A., Margulies, H. D., Shevach, M. E. and Strober, W. 1993. 51Cr release assay of antibody-dependent cell-mediated cytotoxicity (ADCC) In Coligan, E. J., Kruisbeek, M. A., Margulies, H. D., Shevach, M. E. and Strober, W., eds, Current Protocols in Immunology. National Institutes of Health, vol. 1, p. 7.27.1. John Wiley & Sons, New York, USA.
38. Schauer, R. 2004. Sialic acids: fascinating sugars in higher animals and man. Zoology 107:49.
39. GD1a and NMR-based analysis of its binding to a human polyclonal immunoglobulin G fraction with selectivity for O acetylated sialic acids. Glycobiology 6:561.
40. Felsner, P., Steinschifter, W., Fischer, M. et al. 2000. The tumor-associated shift in immunoglobulin G1/G2 is expressed at the messenger RNA level of peripheral B lymphocytes in patients with gynecologic malignancies. Cancer 88:461.
41. Anderhuber, W., Steinschifter, W., Schauenstein, E. et al. 1999. The IgG1/IgG2 subclass shift - a sensitive, tissue non-specific marker for malignancy. Diagnostic performance with squamous cell carcinoma of the head and neck. Br. J. Cancer 79:1777.
42. Jefferis, R., Lund, J. and Pound, J. D. 1998. IgG-Fc-mediated effector functions: molecular definition of interaction sites for effector ligands and the role of glycosylation. Immunol. Rev. 163:59, and references therein.
43. Jefferis, R., Lund, J., Mizutani, H. et al. 1990. A comparative study of the N-linked oligosaccharide structures of human IgG subclass proteins. Biochem. J. 268:529.
44. Farooq, M., Takahashi, N., Arrol, H., Drayson, M. and Jefferis, R. 1997. Glycosylation of polyclonal and paraprotein IgG in multiple myeloma. Glycoconj. J. 14:489.
45. Kondo, A., Hosokawa, Y., Kiso, M., Hasegawa, A. and Kato, I. 1994. Analysis of oligosaccharides of human IgG from serum of leukemia patients. Biochem. Mol. Biol. Int. 32:897.
46. Rudd, P. M., Elliott, T., Cresswell, P., Wilson, I. A. and Dwek, R. A. 2001. Glycosylation and the immune system. Science 291:2370.
47. Deisenhofer, J. 1981. Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9-and 2.8-A resolution. Biochemistry 20:2361.
48. Krotkiewski, H. 1999. Carbohydrate moiety of immunoglobulins in health and pathology. Acta Biochim. Pol. 46:341.
49. Jefferis, R. and Lund, J. 2002. Interaction sites on human IgG-Fc for FcγR: current models. Immunol. Lett. 82:57, and references therein.
50. Duncan, A. R. and Winter, G. 1988. The binding site for C1q on IgG. Nature 332:738.
51. Burton, D. R. 1985. Immunoglobulin G - functional sites. Mol. Immunol. 22:161.
52. Goldsby, R. A., Kindt, T. J., Osborne, B. A., eds. 2000. Kuby Immunology, 4th edn, p. 551. W. H. Freeman and Company, New York.