Preparation and characterization of novel galactosylated chitosan

Journal of China Pharmaceutical University

Volumn 34, Issue 5, 2003, Pages 387-390

  Zhang, Can ^a,b   Ding, Ya ^b   Shen, Jian ^a,c  

^a NANJING UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c NANJING NORMAL UNIVERSITY   (China)

Author keywords

Carrier; Characterization; Chitosan; Hepatocyte targeting; Lactose; Preparation

Indexed keywords

CHITOSAN; GALACTOSE;

ARTICLE; CHEMICAL STRUCTURE; INFRARED SPECTROSCOPY; LIVER CELL; SYNTHESIS;

EID: 13844284491     PISSN: 10005048     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Ogawara K, Yoshida M, Higaki K, et al. Hepatic uptake of polystyrene microspheres in rats: effect of particle size on intrahepatic distribution[J]. J Control Release, 1999,59:15-22.
2. Akamatsu K, Imai M, Yamasaki Y, et al. Disposition characteristics of glycosylated poly(amino acids) as liver cell-specific drug carrier [J]. J Drug Target, 1998,6: 229-239.
3. Moghimi SM,Porter CJH, Muir IS, et al. Non-phagocytic uptake of intravenously injected microspheres in rat spleen: Influence of particle size and hydrophilic coating [J]. Biochem Biophys Res Commun, 1991,177:861-866.
4. Regoeczi E, Debanne MT, Hatton MWC, et al. Elimination of asialofetuin and asialoorosomucoid by the intact rat quantitative aspects of the hepatic clearance mechanism [J]. Biochim Biophys Acta, 1978,541:372-384.
5. Ashwell G, Harford J. Carbohydrate-specific receptors of the liver [J]. Ann Rev Biochem, 1982,51:531-554.
6. Bridges K, Harford J, Ashwell G, et al. Fate of receptor and ligand during endocytosis of asialoglycoproteins by isolated hepatocytes [J]. Proc Natl Acad Sci, 1982,79:350-354.
7. Harford J, Bridges K, Ashwell G, et al. Intracellular dissociation of receptor-bound asialoglycoproteins in cultured hepatocytes [J]. J Biol Chem, 1983,258:3191-3197.
8. Fiume L, Busi C, Mattioli A, et al. Hepatocyte targeting of adenine-9-b-D-arabinofuranoside 59-monophosphate (ara-AMP) coupled to lactosaminated albumin [J]. FEBS Lett, 1981,129:261-264.
9. Fiume L, Busi C, Mattioli A. Lactosaminated human serum albumin as hepatotropic drug carrier rate of uptake by mouse liver [J]. FEBS Lett, 1982,146:42-46.
10. O'Hare KB, Hume IC, Scarlett L, et al. Effect of galactose on interaction of N-(2-hydroxypropyl) methacrylamide copolymers with hepatoma cells in culture: preliminary application to an anticancer agent, daunomycin [J]. Hepatology, 1989,10:207-214.
11. Pimm MV, Perkins AC, Strohalm J, et al. Gamma scintigraphy of a 1-labelled N-(2-hydroxypropyl) methacrylamide copolymer-doxorubicin conjugate containing galactosamine following intravenous administration to nude mice bearing hepatic human colon carcinoma [J]. J Drug Target, 1996,3:385-390.
12. Hashida M, Hirabayashi H, Nishikawa M, et al. Targeted delivery of drugs and proteins to the liver via receptor-mediated endocytosis[J]. J Control Release, 1997,46:129-137.
13. Mahato RI, Takemura S, Akamatsu K, et al. Physicochemical and disposition characteristics of antisense oligonucleotides complexed with glycosylated poly(L-lysine) [J]. Biochem Pharmacol, 1997, 53: 887-895.
14. Masatoshi S, Minoru M, Hitoshi S, et al. Preparation and characterization of water-soluble chitin and chitosan derivatives [J]. Carbohydrate Polymers, 1998,36: 49-59.
15. Samuels RJ. Solid tate characterization of the tructure of chitoan films [J]. J Polymer Sci, Polym Phys Ed, 1981,19:1081-1105.