MDR1 P-glycoprotein assay is severely affected by plastic derived xenobiotics

Placenta

Volumn 26, Issue 2-3, 2005, Pages 271-272

  Atkinson, D E ^a   Sibley, C P ^a   Boote, V ^a   Greenwood, S L ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PLASTIC; RNA; VINBLASTINE; XENOBIOTIC AGENT;

CELL ISOLATION; CYTOTROPHOBLAST; DRUG ACCUMULATION; HUMAN; LETTER; MASS SPECTROMETRY; MULTIDRUG RESISTANCE; PLACENTA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SYNCYTIOTROPHOBLAST; TROPHOBLAST;

ADULT; ARTIFACTS; CELL LINE; FEMALE; HUMANS; LABORATORY TECHNIQUES AND PROCEDURES; P-GLYCOPROTEIN; PLASTICS; PREGNANCY; TROPHOBLASTS; XENOBIOTICS;

EID: 13844276925     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2004.06.004     Document Type: Letter

References (5)

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2. N. Utoguchi G.A. Chandorkar M. Avery K.L. Audus Functional expression of P-glycoprotein in primary cultures of human cytotrophoblasts and BeWo cells Reprod Toxicol 14 3 2000 217-224
3. F. Ushigome H. Takanaga H. Matsuo S. Yanai K. Tsukimori H. Nakano et al. Human placental transport of vinblastine, vincristine, digoxin and progesterone: Contribution of P-glycoprotein Eur J Pharmacol 408 1 2000 1-10
4. Y. Nakamura S. Ikeda T. Furukawa T. Sumizawa A. Tani S. Akiyama et al. Function of P-glycoprotein expressed in placenta and mole Biochem Biophys Res Commun 235 3 1997 849-853
5. P.B. Hoyer Reproductive toxicology: Current and future directions Biochem Pharmacol 62 12 2001 1557-1564