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Volumn 329, Issue 1, 2005, Pages 78-86

n-Alkane and clofibrate, a peroxisome proliferator, activate transcription of ALK2 gene encoding cytochrome P450alk2 through distinct cis-acting promoter elements in Candida maltosa

Author keywords

ALK2; Candida maltosa; Clofibrate; CRE2; Cytochrome P450alk; Gene expression; Peroxisome proliferator; Promoter element; Yeast

Indexed keywords

ALKANE; CLOFIBRATE; CYTOCHROME P450; GLUCOSE; ISOENZYME; OLEIC ACID; PEROXISOME PROLIFERATOR; POLYUNSATURATED FATTY ACID; STEROID HORMONE;

EID: 13844276160     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.01.099     Document Type: Article
Times cited : (7)

References (43)
  • 2
    • 0033199227 scopus 로고    scopus 로고
    • Cytochrome P450 and the individuality of species
    • D.R. Nelson Cytochrome P450 and the individuality of species Arch. Biochem. Biophys. 369 1999 1 10
    • (1999) Arch. Biochem. Biophys. , vol.369 , pp. 1-10
    • Nelson, D.R.1
  • 3
    • 0001270773 scopus 로고
    • Purification of cytochrome P450alk from n-alkane-grown cells of Candida maltosa, and cloning and nucleotide sequencing of the encoding gene
    • M. Takagi, M. Ohkuma, N. Kobayashi, M. Watanabe, and K. Yano Purification of cytochrome P450alk from n-alkane-grown cells of Candida maltosa, and cloning and nucleotide sequencing of the encoding gene Agric. Biol. Chem. 53 1989 2217 2226
    • (1989) Agric. Biol. Chem. , vol.53 , pp. 2217-2226
    • Takagi, M.1    Ohkuma, M.2    Kobayashi, N.3    Watanabe, M.4    Yano, K.5
  • 4
    • 0026184916 scopus 로고
    • Evidence that more than one gene encodes n-alkane-inducible cytochrome P-450s in Candida maltosa, found by two-step gene disruption
    • M. Ohkuma, T. Hikiji, T. Tanimoto, W.H. Schunck, H.G. Muller, K. Yano, and M. Takagi Evidence that more than one gene encodes n-alkane-inducible cytochrome P-450s in Candida maltosa, found by two-step gene disruption Agric. Biol. Chem. 55 1991 1757 1764
    • (1991) Agric. Biol. Chem. , vol.55 , pp. 1757-1764
    • Ohkuma, M.1    Hikiji, T.2    Tanimoto, T.3    Schunck, W.H.4    Muller, H.G.5    Yano, K.6    Takagi, M.7
  • 5
    • 0026161236 scopus 로고
    • CYP52 (cytochrome P450alk) multigene family in Candida maltosa: Molecular cloning and nucleotide sequence of the two tandemly arranged genes
    • M. Ohkuma, T. Tanimoto, K. Yano, and M. Takagi CYP52 (cytochrome P450alk) multigene family in Candida maltosa: Molecular cloning and nucleotide sequence of the two tandemly arranged genes DNA Cell Biol. 10 1991 271 282
    • (1991) DNA Cell Biol. , vol.10 , pp. 271-282
    • Ohkuma, M.1    Tanimoto, T.2    Yano, K.3    Takagi, M.4
  • 6
    • 0028987581 scopus 로고
    • CYP52 (cytochrome P450alk) multigene family in Candida maltosa: Identification and characterization of eight members
    • M. Ohkuma, S. Muraoka, T. Tanimoto, M. Fujii, A. Ohta, and M. Takagi CYP52 (cytochrome P450alk) multigene family in Candida maltosa: Identification and characterization of eight members DNA Cell Biol. 14 1995 163 173
    • (1995) DNA Cell Biol. , vol.14 , pp. 163-173
    • Ohkuma, M.1    Muraoka, S.2    Tanimoto, T.3    Fujii, M.4    Ohta, A.5    Takagi, M.6
  • 7
    • 0023188072 scopus 로고
    • Isolation of the alkane inducible cytochrome P450 (P450alk) gene from the yeast Candida tropicalis
    • D. Sanglard, C. Chen, and J.C. Loper Isolation of the alkane inducible cytochrome P450 (P450alk) gene from the yeast Candida tropicalis Biochem. Biophys. Res. Commun. 144 1987 251 257
    • (1987) Biochem. Biophys. Res. Commun. , vol.144 , pp. 251-257
    • Sanglard, D.1    Chen, C.2    Loper, J.C.3
  • 8
    • 0024441051 scopus 로고
    • Heterogeneity within the alkane-inducible cytochrome P450 gene family of the yeast Candida tropicalis
    • D. Sanglard, and A. Fiechter Heterogeneity within the alkane-inducible cytochrome P450 gene family of the yeast Candida tropicalis FEBS Lett. 256 1989 128 134
    • (1989) FEBS Lett. , vol.256 , pp. 128-134
    • Sanglard, D.1    Fiechter, A.2
  • 9
    • 0026040423 scopus 로고
    • Characterization of a second alkane-inducible cytochrome P450 encoding gene, CYP52A2, from Candida tropicalis
    • W. Seghezzi, D. Sanglard, and A. Fiechter Characterization of a second alkane-inducible cytochrome P450 encoding gene, CYP52A2, from Candida tropicalis Gene 106 1991 51 60
    • (1991) Gene , vol.106 , pp. 51-60
    • Seghezzi, W.1    Sanglard, D.2    Fiechter, A.3
  • 10
    • 0026676224 scopus 로고
    • Identification and characterization of additional members of the cytochrome P450 multigene family CYP52 of Candida tropicalis
    • W. Seghezzi, C. Meili, R. Ruffiner, R. Kuenzi, D. Sanglard, and A. Fiechter Identification and characterization of additional members of the cytochrome P450 multigene family CYP52 of Candida tropicalis DNA Cell Biol. 11 1992 767 780
    • (1992) DNA Cell Biol. , vol.11 , pp. 767-780
    • Seghezzi, W.1    Meili, C.2    Ruffiner, R.3    Kuenzi, R.4    Sanglard, D.5    Fiechter, A.6
  • 11
    • 0032444679 scopus 로고    scopus 로고
    • Cloning and characterization of an n-alkane-inducible cytochrome P450 gene essential for n-decane assimilation by Yarrowia lipolytica
    • T. Iida, A. Ohta, and M. Takagi Cloning and characterization of an n-alkane-inducible cytochrome P450 gene essential for n-decane assimilation by Yarrowia lipolytica Yeast 14 1998 1387 1397
    • (1998) Yeast , vol.14 , pp. 1387-1397
    • Iida, T.1    Ohta, A.2    Takagi, M.3
  • 12
    • 0034666118 scopus 로고    scopus 로고
    • The cytochrome P450ALK multigene family of an n-alkane-assimilating yeast, Yarrowia lipolytica: Cloning and characterization of genes coding for new CYP52 family members
    • T. Iida, T. Sumita, A. Ohta, and M. Takagi The cytochrome P450ALK multigene family of an n-alkane-assimilating yeast, Yarrowia lipolytica: Cloning and characterization of genes coding for new CYP52 family members Yeast 16 2000 1077 1087
    • (2000) Yeast , vol.16 , pp. 1077-1087
    • Iida, T.1    Sumita, T.2    Ohta, A.3    Takagi, M.4
  • 13
    • 0029061875 scopus 로고
    • Proliferation of intracellular membrane structures upon homologous overproduction of cytochrome P-450 in Candida maltosa
    • M. Ohkuma, S.M. Park, T. Zimmer, R. Menzel, F. Vogel, W.H. Schunck, A. Ohta, and M. Takagi Proliferation of intracellular membrane structures upon homologous overproduction of cytochrome P-450 in Candida maltosa Biochim. Biophys. Acta 1236 1995 163 169
    • (1995) Biochim. Biophys. Acta , vol.1236 , pp. 163-169
    • Ohkuma, M.1    Park, S.M.2    Zimmer, T.3    Menzel, R.4    Vogel, F.5    Schunck, W.H.6    Ohta, A.7    Takagi, M.8
  • 14
    • 0032512656 scopus 로고    scopus 로고
    • Isozyme function of n-alkane-inducible cytochromes P450 in Candida maltosa revealed by sequential gene disruption
    • M. Ohkuma, T. Zimmer, T. Iida, W.H. Schunck, A. Ohta, and M. Takagi Isozyme function of n-alkane-inducible cytochromes P450 in Candida maltosa revealed by sequential gene disruption J. Biol. Chem. 273 1998 3948 3953
    • (1998) J. Biol. Chem. , vol.273 , pp. 3948-3953
    • Ohkuma, M.1    Zimmer, T.2    Iida, T.3    Schunck, W.H.4    Ohta, A.5    Takagi, M.6
  • 15
    • 0029143667 scopus 로고
    • In vivo reconstitution of highly active Candida maltosa cytochrome P450 monooxygenase systems in inducible membranes of Saccharomyces cerevisiae
    • T. Zimmer, K. Kaminski, U. Scheller, F. Vogel, and W.H. Schunck In vivo reconstitution of highly active Candida maltosa cytochrome P450 monooxygenase systems in inducible membranes of Saccharomyces cerevisiae DNA Cell Biol. 14 1995 619 628
    • (1995) DNA Cell Biol. , vol.14 , pp. 619-628
    • Zimmer, T.1    Kaminski, K.2    Scheller, U.3    Vogel, F.4    Schunck, W.H.5
  • 16
    • 0030601229 scopus 로고    scopus 로고
    • The CYP52 multigene family of Candida maltosa encodes functionally diverse n-alkane-inducible cytochromes P450
    • T. Zimmer, M. Ohkuma, A. Ohta, M. Takagi, and W.H. Schunck The CYP52 multigene family of Candida maltosa encodes functionally diverse n-alkane-inducible cytochromes P450 Biochem. Biophys. Res. Commun. 224 1996 784 789
    • (1996) Biochem. Biophys. Res. Commun. , vol.224 , pp. 784-789
    • Zimmer, T.1    Ohkuma, M.2    Ohta, A.3    Takagi, M.4    Schunck, W.H.5
  • 17
    • 0032500817 scopus 로고    scopus 로고
    • Relation between evolutionary distance and enzymatic properties among the members of the CYP52A subfamily of Candida maltosa
    • T. Zimmer, T. Iida, W.H. Schunck, Y. Yoshida, A. Ohta, and M. Takagi Relation between evolutionary distance and enzymatic properties among the members of the CYP52A subfamily of Candida maltosa Biochem. Biophys. Res. Commun. 251 1998 244 247
    • (1998) Biochem. Biophys. Res. Commun. , vol.251 , pp. 244-247
    • Zimmer, T.1    Iida, T.2    Schunck, W.H.3    Yoshida, Y.4    Ohta, A.5    Takagi, M.6
  • 18
    • 0030000018 scopus 로고    scopus 로고
    • Characterization of the n-alkane and fatty acid hydroxylating cytochrome P450 forms 52A3 and 52A4
    • U. Scheller, T. Zimmer, E. Kargel, and W.H. Schunck Characterization of the n-alkane and fatty acid hydroxylating cytochrome P450 forms 52A3 and 52A4 Arch. Biochem. Biophys. 328 1996 245 254
    • (1996) Arch. Biochem. Biophys. , vol.328 , pp. 245-254
    • Scheller, U.1    Zimmer, T.2    Kargel, E.3    Schunck, W.H.4
  • 19
    • 2542431032 scopus 로고    scopus 로고
    • A basic helix-loop-helix transcription factor essential for cytochrome P450 induction in response to alkanes in yeast Yarrowia lipolytica
    • S. Yamagami, D. Morioka, R. Fukuda, and A. Ohta A basic helix-loop-helix transcription factor essential for cytochrome P450 induction in response to alkanes in yeast Yarrowia lipolytica J. Biol. Chem. 279 2004 22183 22189
    • (2004) J. Biol. Chem. , vol.279 , pp. 22183-22189
    • Yamagami, S.1    Morioka, D.2    Fukuda, R.3    Ohta, A.4
  • 20
    • 0029937512 scopus 로고    scopus 로고
    • Pip2p: A transcriptional regulator of peroxisome proliferation in the yeast Saccharomyces cerevisiae
    • H. Rottensteiner, A.J. Kal, M. Filipits, M. Binder, B. Hamilton, H.F. Tabak, and H. Ruis Pip2p: A transcriptional regulator of peroxisome proliferation in the yeast Saccharomyces cerevisiae EMBO J. 15 1996 2924 2934
    • (1996) EMBO J. , vol.15 , pp. 2924-2934
    • Rottensteiner, H.1    Kal, A.J.2    Filipits, M.3    Binder, M.4    Hamilton, B.5    Tabak, H.F.6    Ruis, H.7
  • 21
    • 17544371250 scopus 로고    scopus 로고
    • Purification, identification, and properties of a Saccharomyces cerevisiae oleate-activated upstream activating sequence-binding protein that is involved in the activation of POX1
    • Y. Luo, I.V. Karpichev, R.A. Kohanski, and G.M. Small Purification, identification, and properties of a Saccharomyces cerevisiae oleate-activated upstream activating sequence-binding protein that is involved in the activation of POX1 J. Biol. Chem. 271 1996 12068 12075
    • (1996) J. Biol. Chem. , vol.271 , pp. 12068-12075
    • Luo, Y.1    Karpichev, I.V.2    Kohanski, R.A.3    Small, G.M.4
  • 22
    • 0031033366 scopus 로고    scopus 로고
    • A complex containing two transcription factors regulates peroxisome proliferation and the coordinate induction of β-oxidation enzymes in Saccharomyces cerevisiae
    • I.V. Karpichev, Y. Luo, R.C. Marians, and G.M. Small A complex containing two transcription factors regulates peroxisome proliferation and the coordinate induction of β-oxidation enzymes in Saccharomyces cerevisiae Mol. Cell. Biol. 17 1997 69 80
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 69-80
    • Karpichev, I.V.1    Luo, Y.2    Marians, R.C.3    Small, G.M.4
  • 23
    • 0031772260 scopus 로고    scopus 로고
    • Global regulatory functions of Oaf1p and Pip2p (Oaf2p), transcription factors that regulate genes encoding peroxisomal proteins in Saccharomyces cerevisiae
    • I.V. Karpichev, and G.M. Small Global regulatory functions of Oaf1p and Pip2p (Oaf2p), transcription factors that regulate genes encoding peroxisomal proteins in Saccharomyces cerevisiae Mol. Cell. Biol. 18 1998 6560 6570
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 6560-6570
    • Karpichev, I.V.1    Small, G.M.2
  • 24
    • 0030612547 scopus 로고    scopus 로고
    • 6 transcription factors Pip2p and Oaf1p controls induction of genes encoding peroxisomal proteins in Saccharomyces cerevisiae
    • 6 transcription factors Pip2p and Oaf1p controls induction of genes encoding peroxisomal proteins in Saccharomyces cerevisiae Eur. J. Biochem. 247 1997 776 783
    • (1997) Eur. J. Biochem. , vol.247 , pp. 776-783
    • Rottensteiner, H.1    Kal, A.J.2    Hamilton, B.3    Ruis, H.4    Tabak, H.F.5
  • 25
    • 0027159414 scopus 로고
    • Characterization of a transcriptional control element involved in proliferation of peroxisomes in yeast in response to oleate
    • A.W. Einerhand, W.T. Kos, B. Distel, and H.F. Tabak Characterization of a transcriptional control element involved in proliferation of peroxisomes in yeast in response to oleate Eur. J. Biochem. 214 1993 323 331
    • (1993) Eur. J. Biochem. , vol.214 , pp. 323-331
    • Einerhand, A.W.1    Kos, W.T.2    Distel, B.3    Tabak, H.F.4
  • 26
    • 0027369594 scopus 로고
    • A Saccharomyces cerevisiae upstream activating sequence mediates induction of peroxisome proliferation by fatty acids
    • M. Filipits, M.M. Simon, W. Rapatz, B. Hamilton, and H. Ruis A Saccharomyces cerevisiae upstream activating sequence mediates induction of peroxisome proliferation by fatty acids Gene 132 1993 49 55
    • (1993) Gene , vol.132 , pp. 49-55
    • Filipits, M.1    Simon, M.M.2    Rapatz, W.3    Hamilton, B.4    Ruis, H.5
  • 27
    • 0038029928 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Pip2p-Oaf1p regulates PEX25 transcription through an adenine-less ORE
    • H. Rottensteiner, A. Hartig, B. Hamilton, H. Ruis, R. Erdmann, and A. Gurvitz Saccharomyces cerevisiae Pip2p-Oaf1p regulates PEX25 transcription through an adenine-less ORE Eur. J. Biochem. 270 2003 2013 2022
    • (2003) Eur. J. Biochem. , vol.270 , pp. 2013-2022
    • Rottensteiner, H.1    Hartig, A.2    Hamilton, B.3    Ruis, H.4    Erdmann, R.5    Gurvitz, A.6
  • 28
    • 0029945854 scopus 로고    scopus 로고
    • Peroxisome proliferators activate cytochrome P450 genes in an alkane-assimilating yeast, Candida maltosa
    • R. Ohtomo, K. Kobayashi, S. Muraoka, M. Ohkuma, A. Ohta, and M. Takagi Peroxisome proliferators activate cytochrome P450 genes in an alkane-assimilating yeast, Candida maltosa Biochem. Biophys. Res. Commun. 222 1996 790 793
    • (1996) Biochem. Biophys. Res. Commun. , vol.222 , pp. 790-793
    • Ohtomo, R.1    Kobayashi, K.2    Muraoka, S.3    Ohkuma, M.4    Ohta, A.5    Takagi, M.6
  • 29
    • 0024509605 scopus 로고
    • Biochemical mechanisms of induction of hepatic peroxisome proliferation
    • E.A. Lock, A.M. Mitchell, and C.R. Elcombe Biochemical mechanisms of induction of hepatic peroxisome proliferation Annu. Rev. Pharmacol. Toxicol. 29 1989 145 163
    • (1989) Annu. Rev. Pharmacol. Toxicol. , vol.29 , pp. 145-163
    • Lock, E.A.1    Mitchell, A.M.2    Elcombe, C.R.3
  • 30
    • 0027738795 scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR): Structure, mechanisms of activation and diverse functions
    • K. Motojima Peroxisome proliferator-activated receptor (PPAR): Structure, mechanisms of activation and diverse functions Cell Struct. Funct. 18 1993 267 277
    • (1993) Cell Struct. Funct. , vol.18 , pp. 267-277
    • Motojima, K.1
  • 31
    • 0026976982 scopus 로고
    • Regulation of gene expression by fatty acids and fibric acid derivatives: An integrative role for peroxisome proliferator activated receptors, the Belgian Endocrine Society Lecture 1992
    • J. Auwerx Regulation of gene expression by fatty acids and fibric acid derivatives: An integrative role for peroxisome proliferator activated receptors, The Belgian Endocrine Society Lecture 1992 Horm. Res. 38 1992 269 277
    • (1992) Horm. Res. , vol.38 , pp. 269-277
    • Auwerx, J.1
  • 33
    • 0033395836 scopus 로고    scopus 로고
    • The PPARs and PXRs: Nuclear xenobiotic receptors that define novel hormone signaling pathways
    • S.A. Kliewer, J.M. Lehmann, M.V. Milburn, and T.M. Willson The PPARs and PXRs: Nuclear xenobiotic receptors that define novel hormone signaling pathways Recent Prog. Horm. Res. 54 1999 345 367
    • (1999) Recent Prog. Horm. Res. , vol.54 , pp. 345-367
    • Kliewer, S.A.1    Lehmann, J.M.2    Milburn, M.V.3    Willson, T.M.4
  • 34
    • 0028077333 scopus 로고
    • Common pathways of cytochrome P450 gene regulation by peroxisome proliferators and barbiturates in Bacillus megaterium ATCC14581
    • N. English, V. Hughes, and C.R. Wolf Common pathways of cytochrome P450 gene regulation by peroxisome proliferators and barbiturates in Bacillus megaterium ATCC14581 J. Biol. Chem. 269 1994 26836 26841
    • (1994) J. Biol. Chem. , vol.269 , pp. 26836-26841
    • English, N.1    Hughes, V.2    Wolf, C.R.3
  • 35
    • 0025932333 scopus 로고
    • Isolation and sequencing of a gene, C-ADE1, and its use for a host-vector system in Candida maltosa with two genetic markers
    • S. Kawai, T. Hikiji, S. Murao, M. Takagi, and K. Yano Isolation and sequencing of a gene, C-ADE1, and its use for a host-vector system in Candida maltosa with two genetic markers Agric. Biol. Chem. 55 1991 59 65
    • (1991) Agric. Biol. Chem. , vol.55 , pp. 59-65
    • Kawai, S.1    Hikiji, T.2    Murao, S.3    Takagi, M.4    Yano, K.5
  • 36
    • 0029337028 scopus 로고
    • Evidence that the expression of the gene for NADPH-cytochrome P-450 reductase is n-alkane-inducible in Candida maltosa
    • M. Ohkuma, Y. Masuda, S.M. Park, R. Ohtomo, A. Ohta, and M. Takagi Evidence that the expression of the gene for NADPH-cytochrome P-450 reductase is n-alkane-inducible in Candida maltosa Biosci. Biotechnol. Biochem. 59 1995 1328 1330
    • (1995) Biosci. Biotechnol. Biochem. , vol.59 , pp. 1328-1330
    • Ohkuma, M.1    Masuda, Y.2    Park, S.M.3    Ohtomo, R.4    Ohta, A.5    Takagi, M.6
  • 37
    • 0028797646 scopus 로고
    • In vivo evidence for non-universal usage of the codon CUG in Candida maltosa
    • H. Sugiyama, M. Ohkuma, Y. Masuda, S.M. Park, A. Ohta, and M. Takagi In vivo evidence for non-universal usage of the codon CUG in Candida maltosa Yeast 11 1995 43 52
    • (1995) Yeast , vol.11 , pp. 43-52
    • Sugiyama, H.1    Ohkuma, M.2    Masuda, Y.3    Park, S.M.4    Ohta, A.5    Takagi, M.6
  • 38
    • 0031008399 scopus 로고    scopus 로고
    • A natural classification of the basic helix-loop-helix class of transcription factors
    • W.R. Atchley, and W.M. Fitch A natural classification of the basic helix-loop-helix class of transcription factors Proc. Natl. Acad. Sci. USA 94 1997 5172 5176
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5172-5176
    • Atchley, W.R.1    Fitch, W.M.2
  • 39
    • 0029118476 scopus 로고
    • Xenobiotic-inducible transcription of cytochrome P450 genes
    • M.S. Denison, and J.P. Whitlock Jr. Xenobiotic-inducible transcription of cytochrome P450 genes J. Biol. Chem. 270 1995 18175 18178
    • (1995) J. Biol. Chem. , vol.270 , pp. 18175-18178
    • Denison, M.S.1    Whitlock Jr., J.P.2
  • 40
    • 0031164761 scopus 로고    scopus 로고
    • Evolution of a fungal regulatory gene family: The Zn(II)2Cys6 binuclear cluster DNA binding motif
    • R.B. Todd, and A. Andrianopoulos Evolution of a fungal regulatory gene family: The Zn(II)2Cys6 binuclear cluster DNA binding motif Fungal Genet. Biol. 21 1997 388 405
    • (1997) Fungal Genet. Biol. , vol.21 , pp. 388-405
    • Todd, R.B.1    Andrianopoulos, A.2
  • 41
    • 0036223414 scopus 로고    scopus 로고
    • A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance
    • M. de Micheli, J. Bille, C. Schueller, and D. Sanglard A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance Mol. Microbiol. 43 2002 1197 1214
    • (2002) Mol. Microbiol. , vol.43 , pp. 1197-1214
    • De Micheli, M.1    Bille, J.2    Schueller, C.3    Sanglard, D.4
  • 42
    • 0038385183 scopus 로고    scopus 로고
    • A binuclear zinc transcription factor binds the host isoflavonoid- responsive element in a fungal cytochrome p450 gene responsible for detoxification
    • R. Khan, R. Tan, A.G. Mariscal, and D. Straney A binuclear zinc transcription factor binds the host isoflavonoid-responsive element in a fungal cytochrome p450 gene responsible for detoxification Mol. Microbiol. 49 2003 117 130
    • (2003) Mol. Microbiol. , vol.49 , pp. 117-130
    • Khan, R.1    Tan, R.2    Mariscal, A.G.3    Straney, D.4
  • 43
    • 0036289576 scopus 로고    scopus 로고
    • YlALK1 encoding the cytochrome P450ALK1 in Yarrowia lipolytica is transcriptionally induced by n-alkane through two distinct cis-elements on its promoter
    • T. Sumita, T. Iida, S. Yamagami, H. Horiuchi, M. Takagi, and A. Ohta YlALK1 encoding the cytochrome P450ALK1 in Yarrowia lipolytica is transcriptionally induced by n-alkane through two distinct cis-elements on its promoter Biochem. Biophys. Res. Commun. 294 2002 1071 1078
    • (2002) Biochem. Biophys. Res. Commun. , vol.294 , pp. 1071-1078
    • Sumita, T.1    Iida, T.2    Yamagami, S.3    Horiuchi, H.4    Takagi, M.5    Ohta, A.6


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