Electrophysiological-anatomic correlates of ATP-triggered vagal reflex in the dog. V. Role of purinergic receptors

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 288, Issue 3 57-3, 2005, Pages

  Xu, Jiang ^a   Kussmaul, William ^a   Kurnik, Peter B ^a   Al Ahdav, Mohamad ^a   Pelleg, Amir ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

2 ,3 O (2,4,6 trinitrophenyl) ATP; Diinosine pentaphosphate; P2X; Vasovagal syncope

Indexed keywords

2',3' O (2,4,6 TRINITROPHENYL)ADENOSINE TRIPHOSPHATE; ADENOSINE; ADENOSINE TRIPHOSPHATE; ATROPINE; DIINOSINE PENTAPHOSPHATE; MUSCARINIC RECEPTOR BLOCKING AGENT; PURINE P2X1 RECEPTOR; PURINE P2X3 RECEPTOR; PURINE RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRADYCARDIA; CHRONOTROPISM; CONTROLLED STUDY; CORONARY ARTERY CIRCUMFLEX BRANCH; DOG; FEMALE; HEART AUTOMATICITY; HEART ELECTROPHYSIOLOGY; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RIGHT CORONARY ARTERY; SIGNAL TRANSDUCTION; SINUS NODE; SYNCOPE; VAGUS REFLEX;

ADENOSINE; ADENOSINE TRIPHOSPHATE; ANIMALS; BLOOD PRESSURE; CORONARY VESSELS; DOGS; ELECTROPHYSIOLOGY; FEMALE; INJECTIONS, INTRA-ARTERIAL; MALE; RECEPTORS, PURINERGIC P2; REFLEX; VAGUS NERVE; VENTRICULAR FUNCTION, LEFT;

EID: 13844270514     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00553.2004     Document Type: Article

References (34)

1. Abboud FM. Ventricular syncope. Is the heart a sensory organ? N Engl J Med 320: 390-392, 1989.
2. Armour JA, Huang MA, Pelleg A, and Sylven C. Responsiveness of in situ canine nodose ganglion afferent neurons to epicardial mechanical or chemical stimuli. Cardiovasc Res 28: 1218-1225, 1994.
3. Benditt DG, Lurie KG, Adler SW, Sakaguchi S, and Shultz J. Pathophysiology of vasovaga syncope. In: Neurally Mediated Syncope: Investigations and Treatment, edited by Blanc JJ, Benditt DG, and Sutton R, Armonk, NY: Futura, 1996, p.1-24.
4. Burnstock G. P2X receptors in sensory neurons. Br J Anaesth 84: 476-88, 2000.
5. Caterina MJ, Schumacher MA, Tominaga M, Rozen TA, Levine JD, and Julius D. The capcaisin receptor: a heat-activated ion channel in the pain pathway. Nature 389: 816-824, 1997.
6. Chen CC, Akopian AN, Sivilotti L, Colquhoun D, Burnstock G, and Wood JN. A P2X purinoceptor expressed by a subset of sensory neurons. Nature 377: 428-431, 1995.
7. Dauchot P, Gravestein JS. Bradycardia after myocardial ischemia and its treatment with atropine. Anesthesiology 44: 501-518, 1976.
8. 2/3 receptors and between two P2X receptors in rat sensory neurons. Br J Pharmacol 130: 1378-1384, 2000.
9. Hamilton SG, Wade A, and McMahon SB. The effects of inflammation and inflammatory mediators on nociceptive behavior induced by ATP analogs in the rat. Br J Pharmacol 126: 326-332, 1999.
10. Hurt CM, Wang L, Xu J, Sterious W, and Pelleg A. Electrophysiological- anatomic correlates of ATP-triggered vagal reflex in dogs. II: Vagal afferent traffic. Am J Physiol Heart Circ Physiol 267: H1093-H1097, 1994.
11. Katchanov G, Xu J, Clay A, and Pelleg A. Electrophysiological-anatomic correlates of ATP-triggered vagal reflex in the dog. IV. Stimulation of LV vagal afferents. Am J Physiol Heart Circ Physiol 272: H1899-H1903, 1997.
12. Katchanov G, Xu J, Hurt CM, Pelleg A. Electrophysiological-anatomic correlates of ATP-triggered vagal reflex in the dog. III. Role of cardiac afferents. Am J Physiol Heart Circ Physiol 270: H1785-H1790, 1996.
13. Katchanov G, Xu J, Schulman ES, and Pelleg A. ATP causes neurogenic bronchocontriction in the dog. Drug Dev Res 45: 342-349, 1998.
14. 3 receptor subunits can account for ATP-gated currents in sensory neurons. Nature 377: 432-435, 1995.
15. North RA. Molecular physiology of P2X receptors. Physiol Rev 82: 1013-1067, 2002.
16. Pelleg A, Belhassen B, Ilia R, and Laniado S. Comparative electrophysiologic effects of ATP and adenosine in the canine heart: influence of atropine, propranolol, vagotomy, dipyridamole, and aminophylline. Am J Cardiol 55: 571-576, 1985.
17. Pelleg A, Belhassen B, Terdiman R, Shargordsky B, and Laniado S. Electrophysiological effects of adenosine triphosphate and adenosine in the canine heart (Abstract). Fed Proc 42: 731, 1983.
18. Pelleg A and Hurt CM. Mechanism of ATP's action on canine pulmonary vagal fibre nerve terminals. J Physiol 490: 265-275, 1996.
19. Pelleg A, Hurt CM, Soler-Baillo JM, and Polansky M. Electrophysiological- anatomic correlates of ATP-triggered vagal reflex in dogs. Am J Physiol Heart Circ Physiol 265: H681-H690, 1993.
20. Pelleg A, Katchanov G, and Xu J. Autonomic neural control of cardiac function: modulation by adenosine and ATP. Am J Cardiol 79: 11-14, 1997.
21. Pelleg A, Mitsuoka T, and Michelson EL. Adenosine mediates the negative chronotropic action of adenosine 5′-triphosphate in the canine sinus node. J Pharmacol Exp Ther 242: 791-795, 1987.
22. Pelleg A, Vassort G, and Auchampach JA. ATP and adenosine signal transductions in the cardiovascular system. In: Heart Physiology and Pathophysiology (4th ed.), edited by Sperelakis N, Kurachi Y, Terzic A, and Cohen MV, San Diego: Academic, 2002, p. 633-655.
23. Pelleg A, Xu J, Kussmaul W, and Kurnik PP. Left ventricular P2X2/3 receptors mediate ATP-triggered vagal depressor reflex (Abstract). Circulation 108: IV-57, 2003.
24. Perez-Paredes M, Pico AF, Sanchez VJG, Exposito OE, Gonzalvez OM, Gonzalez CE, Inigo GL, Espinosa GMD, Florenciano SR, and Ruiperez AJA. Role of adenosine triphosphate (ATP) in head-up tilt-induced syncope. Rev Esp Cardiol 51: 129-135, 1998.
25. Ralevic V and Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev 50: 413-492, 1998.
26. Sylven C. Mechanisms of pain in angina pectoris - a critical review of the adenosine hypothesis. Cardiovasc Drugs Ther 7: 745-759, 1993.
27. Thames MD, Dibner-Dunlap ME, Minisi AJ, and Kinugawa T. Reflexes mediated by cardiac sympathetic afferents during myocardial ischaemia: role of adenosine. Clin Exp Pharmacol Physiol 23: 709-714, 1996.
28. Thomas S, Virginio C, North RA, and Surprenant A. The antagonist trinitrophenyl-ATP reveals co-existence of distinct P2X receptor channels in the rat nodose ganglion. J Physiol 509: 411-417, 1998.
29. Tsuda M, Koizumi S, Kita A, Shigemoto Y, Ueno S, and Inoue K. Mechanical allodynia caused by intraplantar injection of P2X agonist in rats: involvement of hetromeric receptor signaling in capsaicin-insensitive primary afferent neurons. J Neurosci 20: 1-5, 2000.
30. Ueno S, Tsuda M, Iwanaga T, and Inoue K. Cell type-specific ATP-activated responses in rat dorsal root ganglion neurons. Br J Pharmacol 126: 429-436, 1999.
31. 2/3 receptors. Mol Pharmacol 53: 969-973, 1998.
32. 3 receptor subunits in rat and monkey sensory neurons and their central terminals. Neuropharmacol 36: 1229-1242, 1997.
33. Webb SW, Adgey AAJ, and Pantridge JF. Autonomic disturbance at the onset of acute myocardial infarction. Br Med J 3: 89-92, 1972.
34. Widdicombe J. Neuroregulation of cough: implications for drug therapy. Curr Opin Pharmacol 2: 256-263, 2002.