Initial risk assessment for three β-blockers found in the aquatic environment

Chemosphere

Volumn 59, Issue 2, 2005, Pages 199-205

  Cleuvers, Michael ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Bioconcentration factor; Internal effect concentration; Log P; Mixture toxicity; Narcosis; Pharmaceuticals

Indexed keywords

ADDITION REACTIONS; CONCENTRATION (PROCESS); ECOSYSTEMS; MEMBRANES; MIXTURES; RISK ASSESSMENT;

ATENOLOL; BETA-BLOCKERS; ECOTOXICITY; LEMNA MINOR;

TOXICITY;

ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; METOPROLOL; PROPRANOLOL;

AQUATIC ENVIRONMENT; CHEMICAL POLLUTANT; ECOTOXICOLOGY; RISK ASSESSMENT; ZOOPLANKTON;

ACCURACY; ALGA; ANESTHESIA; AQUATIC ENVIRONMENT; ARTICLE; BIOACCUMULATION; DAPHNIA; ECOTOXICITY; EMPIRICISM; ENVIRONMENTAL IMPACT; MEMBRANE DAMAGE; NONHUMAN; RISK ASSESSMENT; TOXICITY TESTING;

ALGAE; DAPHNIA; DAPHNIA MAGNA; DESMODESMUS SUBSPICATUS; LEMNA MINOR;

EID: 13844267823     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2004.11.090     Document Type: Article

References (42)

1. S.G. Abernethy, D. Mackay, and L.S. McCarthy Volume fraction correlation for narcosis in aquatic organisms: the key role of partitioning Environ. Toxicol. Chem. 7 1998 469 481
2. R. Altenburger, M. Nendza, and G. Schüürmann Mixture toxicity and its modelling by quantitative structure-activity relationships Environ. Toxicol. Chem. 22 2003 1900 1915
3. T. Backhaus, R. Altenburger, W. Boedeker, M. Faust, M. Scholze, and L.H. Grimme Predictability of the toxicity of a multiple mixture of dissimilarly acting chemicals to Vibrio fischeri Environ. Toxicol. Chem. 19 2000 2348 2356
4. M.C. Berenbaum The expected effect of a combination of agents: the general solution J. Theoret. Biol. 114 1985 413 431
5. Bramaz, N., Richter, M., Eggen, R.I.L., Escher, B.I., 2004. Modes of toxic action and mixture toxicity of pharmaceuticals in aquatic organisms. Poster presentation on the 14th SETAC Europe annual meeting, Prague, Czesk
6. R.S. Cantor The lateral pressure profile in membranes: a physical mechanism of general anesthesia Biochemistry 36 1997 2340 2344
7. M.C. Calleja, G. Personne, and P. Geladi Comparative acute toxicity of the first 50 multicentre evaluation of in vitro cytotoxicity chemicals to aquatic non-vertebrates Arch. Environ. Contam. Toxicol. 26 1994 69 78
8. M. Cleuvers Aquatic Ecotoxicology of selected pharmaceutical agents-algal and acute Daphnia tests UWSF-Z. Umweltchem. Ökotox. 14 2002 85 89
9. M. Cleuvers Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects Toxicol. Lett. 142 2003 185 194
10. M. Cleuvers Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen and acetylsalicylic acid Ecotoxicol. Environ. Saf. 59 2004 309 315
11. Commission of the European Communities, 1992. Methods for determination of ecotoxicity; Annex V, C.2, Daphnia, acute toxicity to Daphnia. L 383A, 172-178. EEC Directive 92/69/EEC
12. Commission of the European Communities, 1993. Methods for determination of ecotoxicity; Annex V, C.3, Algal inhibition test. L 383A, 179-186. EEC Directive 92/69/EEC
13. Commission of the European Communities, 1996. Technical guidance document in support of commission directive 93/67/EEC on risk assessment for new notified substances and commission regulation (EC) No 1488/94 on risk assessment for existing substances. Part II: Environmental Risk Assessment. Office for official publications of the European Communities, Luxembourg
14. B.I. Escher, and J.L.M. Hermens Modes of action in ecotoxicology: their role in body burdens, species sensitivity, QSARs, and mixture effects Environ. Sci. Technol. 36 2002 4201 4217
15. B. Ferrari, N. Paxeus, R. Lo Giudice, A. Pollio, and J. Garric Ecotoxicological impact of pharmaceuticals found in treated waste waters: study of carbamazepine, clofibric acid and diclofenac Ecotoxicol. Environ. Saf. 55 2003 359 370
16. N.P. Franks, and W.R. Lieb Mechanisms of general anesthesia Environ. Health Perspect. 87 1990 199 205
17. K.P. Henschel, A. Wenzel, M. Diederich, and A. Fliedner Environmental hazard assessment of pharmaceuticals Reg. Toxicol. Pharmacol. 25 1997 220 225
18. R. Hirsch, T.A. Ternes, K. Haberer, and K.L. Kratz Determination of beta-blockers and β-sympathomimetics in the aquatic environment Vom Wasser 87 1996 263 274
19. D.B. Huggett, B.W. Brooks, B. Peterson, C.M. Foran, and D. Schlenk Toxicity of select beta adrenergic receptor-blocking pharmaceuticals (beta-blockers) on aquatic organisms Arch. Environ. Contain. Toxicol. 43 2002 229 235
20. ISO (International Organization for Standardization), 2001. Water quality-determination of the toxic effect of water constituents and waste water to duckweed (Lemna minor)-duckweed growth inhibition test
21. ISO (International Organization for Standardization), 1996. Water quality-determination of the inhibition of the mobility of Daphnia magna Straus (Cladocera, Crustacea)-acute toxicity test
22. O.A.H. Jones, N. Voulvoulis, and J.N. Lester Aquatic environmental assessment of the top 25 English prescription pharmaceuticals Water Res. 36 2002 5013 5022
23. B. Klüttgen, U. Dülmer, M. Engels, and H.T. Ratte ADaM, an artificial freshwater for the culture of zooplankton Water Res. 28 1994 743 746
24. H. Lilius, B. Isomaa, and T. Holmström A comparison of the toxicity of 50 reference chemicals to freshly isolated rainbow trout hepatocytes and Daphnia magna Aquatic Toxicol. 30 1994 47 60
25. R.L. Lipnick Structure-activity-relationships G.M. Rand Fundamentals of aquatic toxicology 1995 Taylor & Francis London, United Kingdom 609 655
26. L.S. McCarthy, and D. MacKay Enhancing ecotoxicological modelling and assessment Environ. Sci. Technol. 27 1993 1719 1728
27. E. Mutschler, G. Geisslinger, H.K. Kroemer, and M. Schäfer-Korting Arzneimittelwirkungen 2001 Wissenschaftliche Verlagsgesellschaft mbH Stuttgart, Germany
28. Organisation for Economic Co-Operation and Development (OECD), 2001. Harmonised integrated classification system for human health and environmental hazards of chemical substances and mixtures
29. F. Sacher, F.T. Lange, H.J. Brauch, and I. Blankenhorn Pharmaceuticals in groundwater. Analytical methods and results of a monitoring program in Baden Würtemberg, Germany J. Chromatogr. A 938 2001 199 210
30. H. Sanderman Induction of lipid-protein dismatch by xenobiotics with general membrane targets Biochim. Biophys. Acta 1150 1993 130 133
31. Schwabe, U., Paffrath, D. (Eds.), 2004. Arzneiverordnungsreport 2003, Springer Press, Berlin, Germany
32. D.L. Sedlak, and K.E. Pinkston Factors affecting the concentrations of pharmaceuticals released to the aquatic environment Water Resour. Update 120 2001 56 64
33. R.A. Steinberg Use of Lemna as test organism Chronica Botanica 7 1943 420
34. R.A. Steinberg Mineral requirements of Lemna minor Plant Physiol. 21 1946 42 44
35. T.A. Ternes Occurrence of drugs in German sewage treatment plants and rivers Water Res. 32 1998 3245 3260
36. C.J. Van Leeuwen, P.T.J. van der Zandt, T. Aldenberg, H.J.M. Verhaar, and J.L.M. Hermens Application of QSARs, extrapolation and equilibrium partitioning in aquatic assessment: I. Narcotic industrial pollutants Environ. Toxicol. Chem. 11 1992 267 282
37. W.M.G.M. Van Loon, M.E. Verwoerd, F.G. Eijnker, C.J. van Leeuwen, P. van Duyn, C. van de Guchte, and J.L.M. Hermens Estimating total body residues and baseline toxicity of complex organic mixtures in effluents and surface waters Environ. Toxicol. Chem. 16 1997 1358 1365
38. A.P. van Wezel, and A. Opperhuizen Narcosis due to environmental pollutants in aquatic organisms: residue-based toxicity, mechanisms, and membrane burdens Crit. Rev. Toxicol. 25 1995 255 279
39. Verhaar, H.J.M., Mulder, W., Hermens, J.L.M., 1995. QSARs for ecotoxicity, in: Hermens, J.L.M. (Ed.), Overview of structure-activity relationships for environmental endpoints, part 1: General outline and procedure. Report prepared within the framework of the project "QSAR for prediction of fate and effect of chemicals in the environment", Environmental Technologies RTD Programme, European Commission, contract number EV5V-CT92-0211
40. H.J.M. Verhaar, C.J. van Leeuwen, and J.L.M. Hermens Classifying environmental pollutants. 1. Structure-activity relationships for prediction of aquatic toxicology Chemosphere 25 1992 471 491
41. S. Webb A data-based perspective on the environmental risk assessment of human pharmaceuticals I-collation of available ecotoxicity data K. Kümmerer Pharmaceuticals in the environment. Sources, fate, effects and risks 2001 Springer Verlag Berlin, Germany 175 202
42. E. Zuccato, D. Calamari, M. Natangelo, and R. Fanelli Presence of therapeutic drugs in the environment Lancet 355 2000 1789 1790