A flexible carbanionic approach to protected trans-(2R,3S)-2-substituted 3-aminopyrrolidines: Application to the asymmetric synthesis of (+)-absouline

Synlett

Volumn , Issue 2, 2005, Pages 231-234

  Tang, Tian ^a   Ruan, Yuan Ping ^a   Ye, Jian Liang ^a   Huang, Pei Qiang ^a,b  

^a XIAMEN UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

Author keywords

Additions; Asymmetric synthesis; Carbanions; Pyrrolidine; Reductive lithiation

Indexed keywords

1 AMINOPYRROLIZIDINE ALKALOID; 2 LITHIOPIPERIDINE DERIVATIVE; 3 AMINO 2 THIOPHENYLPYRROLIDINE; ABSOULINE; ANION; ISOABSOULINE; LABURNAMINE; PIPERIDINE DERIVATIVE; PYRROLIDINE DERIVATIVE; PYRROLIZIDINE ALKALOID; SULFIDE; UNCLASSIFIED DRUG;

ADDITION REACTION; ARTICLE; ASYMMETRIC SYNTHESIS; CHEMICAL STRUCTURE; LITHIATION; REACTION ANALYSIS; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

EID: 13844265719     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-837194     Document Type: Article

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64. We thank Dr. C. Poupat (Institut de Chimie des Substances Naturelles, CNRS, France) for sending us a sample of natural absouline.