Neural cell adhesion molecules (NCAM) and NCAM-PSA expression in neuroendocrine lung tumors

American Journal of Surgical Pathology

Volumn 22, Issue 10, 1998, Pages 1267-1276

  Lantuejoul, Sylvie ^a   Moro, Denis ^b   Michalides, Rob J A M ^c   Brambilla, Christian ^b   Brambilla, Elisabeth ^a,b,d  

^a Laboratoire de Pathologie Cellulaire   (France)

^b Lung Cancer Research Group   (France)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d CENTRE HOSPITALIER   (France)

Author keywords

123C3; Mab 735; NCAM; NCAM PSA; Neuroendocrine tumors lung cancer

Indexed keywords

CHROMOGRANIN A; NERVE CELL ADHESION MOLECULE; POLYSIALIC ACID;

ARTICLE; CARCINOID; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; LUNG ADENOCARCINOMA; LUNG SMALL CELL CANCER; LUNG TUMOR; MAJOR CLINICAL STUDY; NEUROENDOCRINE TUMOR; SQUAMOUS CELL CARCINOMA;

ADENOCARCINOMA; ANTIBODIES, MONOCLONAL; CARCINOID TUMOR; CARCINOMA, SMALL CELL; CARCINOMA, SQUAMOUS CELL; CELL COUNT; CHROMOGRANIN A; CHROMOGRANINS; DIAGNOSIS, DIFFERENTIAL; HUMANS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; NEURAL CELL ADHESION MOLECULES; NEUROENDOCRINE TUMORS; RETROSPECTIVE STUDIES; SIALIC ACIDS; SURVIVAL RATE;

EID: 0031658277     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-199810000-00012     Document Type: Article

References (39)

1. Arrigoni MG, Woolner LB, Bernatz PE. Atypical carcinoid tumors of the lung. J Thorac Surg 1972;64:413-21.
2. Beiske K, Mykle Bust AT, Aamdal S, Langholm D, Jakobsen E, Fodstad O. Detection of bone marrow metastases in small cell lung cancer patients. Am J Pathol 1992;141:531-8.
3. Beredsen HH, de Leij L, Poppema S, Postmus P, Boes A, Sluiter H, The H. Clinical characterization of non-small-cell lung cancer tumors showing neuroendocrine differentiation features. J Clin Oncol 1989;7:1614-20.
4. Beverley PCL, Souhami RL, Bobrow L. First International Workshop on Small Cell Lung Cancer. The Royal Society, London, 1987.
5. Brambilla E, Moro D, Veale D, Brambilla C. Basal cell (basaloid) carcinoma of the lung: a new morphologic and phenotypic entity with separate prognostic significance. Hum Pathol 1992;23:993-1093.
6. Brambilla E, Veale D, Moro D, Morel F, Dubois F, Brambilla C. Neuroendocrine phenotype in lung cancer: comparison of immunohistochemistry with biochemical determination of enolase isoenzymes. Am J Clin Pathol 1992;98:88-97.
7. Brezicka FT, Olling S, Bergman B, et al. Immunohistochemical detection of two small cell lung carcinoma-associated antigens defined by Mab F12 and 123C3 in bronchoscopy biopsy tissues. APMIS 1991;99:797-802.
8. Cunnigham BA, Hoffman S, Rutishauser U, Hemperly JJ, Edelman GM. Molecular topography of the neural cell adhesion molecule NCAM: surface orientation and location of sialic acid-rich and binding regions. Proc Natl Acad Sci USA 1983;80:3116-20.
9. Edelman GM. Cell adhesion molecules. Science 1983;219:450-7.
10. Feizi T. Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are oncodevelopmental antigens. Nature 1985;314:53-7.
11. Finne J. Occurrence of a unique polysialosyl carbohydrate units in glycoproteins of developing brain. J Biol Chem 1982;257:1966-70.
12. Finne J, Mikela PH. Cleavage of the polysialosyl units of brain glycoproteins by bacteriophage endosialidase. J Cell Biol 1985; 260;1265-70.
13. Frosch M, Gorgen I, Boulnois GJ, Timmis KN, Bitter-Suermann D. NZB mouse system for production of monoclonal antibodies to weak bacterial antigens: isolation of an IgG antibody to the polysaccharide capsules of Escherichia coli K1 and group B meningococci. Proc Natl Acad Sci USA 1985;82:1194-8.
14. Gould VE, Wiedenmann B, Lee I, et al. Synaptophysine expression in neuroendocrine neoplasms as determined by immunocytochemistry. Am J Pathol 1987;126:243-57.
15. Graziano S, Mazid R, Newman N, et al. The use of neuroendocrine immunoperoxidase markers to predict chemotherapy response in patients with non-small-cell lung cancer. J Clin Oncol 1989;7: 1398-406.
16. Jin L, Hemperly JJ, Lloyd R. Expression of neural cell adhesion molecule in normal and neoplastic human neuroendocrine tissues. Am J Pathol 1991;138:961-9.
17. Kibbelaar RE, Moolenaar CEC, Michalides RJAM, Bitter-Suermann D, Addis BJ, Mooi WJ. Expression of the embryonal neural cell adhesion molecule NCAM in lung carcinoma: diagnostic-usefulness of monoclonal antibody 735 for the distinction between small cell lung carcinoma and non small cell lung cancer. J Pathol 1989;159:23-8.
18. Kibbelaar RE, Moolenaar KEC, Michalides RJAM, et al. Neural cell adhesion molecule expression, neuroendocrine differentiation and prognosis in lung carcinoma. Eur J Cancer 1991;27:431-5.
19. Komminoth P, Roth J, Lackie PM, Bitter-Suermann D, Heitz PU. Polysialic acid of the neural cell adhesion molecule distinguish small cell lung carcinoma from carcinoids. Am J Pathol 1991;139: 297-304.
20. Kwa HB, Michalides RJAM, Dijkman JH, Mooi WJ. The prognosis value of NCAM, p53 and cyclin D1 in resected non-small cell lung cancer. Lung Cancer 1996;14:207-17.
21. Michalides R, Kwa B, Springall D, Van Zandwijk N, Koopman J, Hilkens J, Mooi W. NCAM and lung cancer. Int J Cancer 1994;(suppl 8):34-7.
22. Molenaar W, de Leij L, Trojanoswski JQ. Neuroectodermal tumors of the peripheral and the central nervous system share neuroendocrine NCAM related antigens with small cell lung carcinomas. Acta Neuropathol 1991;83:46-54.
23. Moolenaar CECK, Muller EJ, Schol DJ, Figdor CG, Bock E, Bitter-Suermann D, Michalides RJAM. Expression of neural cell adhesion molecule related sialoglycoprotein in small cell lung cancer and neuroblastoma cell lines H69 and CHP-212. Cancer Res 1990; 50:1102-6.
24. Nybroe O'Linnemann D, Bock E. Heterogeneity of soluble neural cell adhesion molecule. J Neurochem 1989;53:1372-8.
25. Pujol JL, Simony J, Demoly P, et al. Neural cell adhesion molecule and prognosis of surgical resected lung cancer. Am Rev Respir Dis 1993;148:1071-5.
26. Pujol JL, Simony J, Laurent JC, et al. Phenotypic heterogeneity studied by immunohistochemistry and aneuploidy in non-small cell lung cancers. Cancer Res 1989;49:2797-802.
27. Roth J, Zuber C, Wagner P, et al. Presence of the long chain form of polysialic acid of the neural cell adhesion molecule in Wilm's tumor. Am J Pathol 1988;133:227-39.
28. Rougon G, Dubois C, Buckley N, Magnani JL, Zollinger W. A monoclonal antibody against meningococcus group B polysaccharides distinguishes embryonic from adult NCAM. J Cell Biol 1986; 103:2429-37.
29. Rutishauser U, Hoffman S, Edelman GM. Binding properties of a cell adhesion molecule from neural tissue. Proc Natl Acad Sci USA 1982;79:685-9.
30. Rutishauser U, Thiery JP, Brackenbury R, Sela BA, Edelman GM. Mechanisms of adhesion among cells from neural tissues of chick embryo. Proc Natl Acad Sci USA 1976;73:577-81.
31. Scheidegger EP, Lackie PM, Papay J, Roth J. In vitro and in vivo growth of clonal sublines of human small cell carcinoma is modulated by polysialic acid of the neural cell adhesion molecule. Lab Invest 1994;70:95-106.
32. Schleusener JT, Tazelaar HD, Jung SH, et al. Neuroendocrine differentiation is an independent prognostic factor in chemotherapy-treated nonsmall cell lung carcinoma. Cancer 1996;77: 1284-91.
33. Schol DJ, Mooi WJ, Van Der Gugten AA, Wagenaar SS, Hilgers J. Monoclonal antibody 123C3 identifying small cell carcinoma phenotype in lung tumours recognizes mainly, but not exclusively, endocrine and neuron-supporting normal tissues. Int J Cancer 1988;(suppl 2):34-40.
34. Stahel RA, Gilks WR, Lehmann HP, Schenker T. Third International Workshop on Lung Tumor and Differentiation Antigens: overview of the results of the central data analysis. Int J Cancer 1994;(suppl 8):6-26.
35. Takamatsu K, Auerbach B, Gerardy-Schahn R, Eckhardt M, Jaques G, Madry N. Characterization of tumor-associated neural cell adhesion molecule in human serum. Cancer Res 1994;54: 2598-603.
36. Thiery JP, Durand JL, Rutishauser U, Edelman GM. Cell adhesion molecules in early chicken embryogenesis. Proc Natl Acad Sci USA 1982;79:6737-41.
37. Travis WD, Linnoila RI, Tsokos MG, et al. Neuroendocrine tumors of the lung with proposed criteria for large cell neuroendocrine carcinoma. Am J Surg Pathol 1991;15:529-53.
38. UICC TNM. Classification of Malignant Tumors, 4th ed. New York: Springer-Verlag; 1988:71-6.
39. World Health Organization. Histological Typing of Lung Tumors. Geneva: World Health Organization: 1981.