In vivo quantitative 1H MRS of cerebellum and evaluation of quantitation reproducibility by simulation of different levels of noise and spectral resolution

Magnetic Resonance Imaging

Volumn 22, Issue 10 SPEC. ISS., 2004, Pages 1385-1393

  Macrì, Maria Antonietta ^a,b   Garreffa, Girolamo ^a,b,c,d   Giove, Federico ^a,b,c   Guardati, Manuela ^a,b,c   Ambrosini, Anna ^d   Colonnese, Claudio ^d   Maraviglia, Bruno ^a,b,c  

^a MUSEO STORICO DELLA FISICA E CENTRO STUDI E RICERCHE ENRICO FERMI   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITÀ DI ROMA LA SAPIENZA   (Italy)

^d Inst Ricovero Cura Carattere S   (Italy)

Author keywords

Cerebellum; In vivo; LCModel; Metabolite concentration; Quantification; Short TE 1H MRS; Spectral analysis

Indexed keywords

ADULT; BRAIN RADIOGRAPHY; CEREBELLUM; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; FEMALE; HUMAN; IN VIVO STUDY; MALE; METABOLITE; MODEL; NOISE; NORMAL HUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SIMULATION; ARTICLE; ARTIFACT; BODY WATER; CHEMISTRY; IMAGE ENHANCEMENT; IMAGE PROCESSING; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ILEX COOKII;

ASPARTIC ACID; CHOLINE; CREATINE; DIPEPTIDE; DRUG DERIVATIVE; GLUTAMIC ACID; GLUTAMINE; HYDROGEN; INOSITOL; N ACETYL 1 ASPARTYLGLUTAMIC ACID; N ACETYLASPARTIC ACID; N-ACETYL-1-ASPARTYLGLUTAMIC ACID; N-ACETYLASPARTATE; NEUROPEPTIDE;

ADULT; ARTIFACTS; ASPARTIC ACID; BODY WATER; CEREBELLUM; CHOLINE; CREATINE; DIPEPTIDES; FEMALE; GLUTAMIC ACID; GLUTAMINE; HUMANS; HYDROGEN; IMAGE ENHANCEMENT; IMAGE PROCESSING, COMPUTER-ASSISTED; INOSITOL; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NEUROPEPTIDES;

EID: 13544264633     PISSN: 0730725X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mri.2004.10.021     Document Type: Conference Paper

References (22)

1. T. Michaelis, K. Merboldt, H. Bruhn, W. Hanicke, and J. Frahm Absolute concentrations of metabolites in the adult human brain in vivo: quantification of localized proton MR spectra Radiology 187 1993 219 227
2. 1H MRS spectroscopy of the human brain at 7 T Magn. Reson. Med. 46 2001 451 456
3. 1H NMR spectroscopy of the mouse brain at 9.4 T Magn. Reson. Med. 52 2004 478 484
4. 1H NMR spectroscopy of individual human brain metabolites at moderate field strengths Magn. Reson. Imaging 21 2003 1295 1302
5. K. Ugurbil, G. Adriany, P. Andersen, W. Chen, M. Garwood, and R. Gruetter Ultrahigh field magnetic resonance imaging and spectroscopy Magn. Reson. Imaging 21 2003 1263 1281
6. 1H proton spectroscopic imaging of the human brain Magn. Reson. Imaging 22 2004 523 528
7. L. Vanhamme, A. van den Boogaart, and S. Van Huffel Improved method for accurate and efficient quantification of MRS data with use of priori-knowledge J. Magn. Reson. 129 1997 35 43
8. A. Van den Boogaart, A. Van Hecke, P. Van Huffel, S. Graveron-Demilly, D. Van Ormondt, and R. de Beer MRUI: a graphical user interface for accurate routine MRS data analysis Proceedings of the European Society of Magnetic Resonance in Medicine and Biology 13th Annual Meeting 1996 Prague 318
9. S.W. Provencher Estimation of metabolite concentrations from localized in vivo proton NMR spectra Magn. Reson. Med. 30 1993 672 679
10. S.W. Provencher LCModel & LCMgui user's manual http://S-provencher. com 2004
11. V. Govindaraju, K. Young, and A.A. Maudsley Proton NMR chemical shifts and coupling constants for brain metabolites NMR Biomed. 13 2000 129 153
12. The MathWorks, Inc. Matlab http://www.mathworks.com
13. U. Klose In vivo proton spectroscopy in presence of eddy currents Magn. Reson. Med. 14 1990 26 30
14. J. Frahm, H. Bruhn, M.L. Gyngell, K.D. Merboldt, W. Hanicke, and R. Sauter Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites Magn. Reson. Med. 11 1989 47 63
15. S. Cavassila, S. Deval, C. Huegen, D. van Ormondt, and D. Graveron-Demilly Cramér-Rao bounds: an evaluation tool for quantitation NMR Biomed. 14 2001 278 283
16. J. Hennig, H. Pfister, T. Ernst, and D. Ott Direct absolute quantification of metabolites in the human brain with in vivo localized proton spectroscopy NMR Biomed. 5 1992 193 199
17. P.C. van Zijl, and C.T. Moonen In situ changes in purine nucleotide and N-acetyl concentrations upon inducing global ischemia in cat brain Magn. Reson. Med. 29 1993 381 385
18. 1H and 3 1P MRS of PCA extracts of postmortem Alzheimer's disease brain Neurobiol. Aging 17 1996 349 357
19. 1H human brain spectra by LCModel and AMARES Magn. Reson. Med. 51 2004 904 912
20. 1H-magnetic resonance spectroscopy of human brain: influence of composition and parameterization of the basis set in linear combination model-fitting Magn. Reson. Med. 48 2002 440 453
21. 1H spectra with LCModel NMR Biomed. 14 2001 260 264
22. 1H NMR spectra of the rat brain J. Magn. Reson. 141 1999 104 120