Elevated expression of p21 (WAF1/Cip1) in hormonally active pituitary adenomas

Annals of Diagnostic Pathology

Volumn 9, Issue 1, 2005, Pages 6-10

  Neto, Antonio G ^a   McCutcheon, Ian E ^b   Vang, Russell ^c   Spencer, M Loreto ^d   Zhang, Wei ^b   Fuller, Gregory N ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CONCEPCIÓN   (Chile)

Author keywords

Cyclin dependent kinase inhibitor; p21; Pituitary adenoma; WAF1 Cip1

Indexed keywords

CORTICOTROPIN; FOLLITROPIN; GROWTH HORMONE; LUTEINIZING HORMONE; PROLACTIN; PROTEIN P21; THYROTROPIN;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE EXPRESSION; GENE OVEREXPRESSION; HORMONE SYNTHESIS; HUMAN; HUMAN TISSUE; HYPOPHYSIS ADENOMA; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; PRIORITY JOURNAL;

EID: 13444311908     PISSN: 10929134     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.anndiagpath.2004.10.002     Document Type: Article

References (23)

1. W.S. El-Deiry, T. Tokino, and V.E. Velculescu WAF1, a potential mediator of p53 tumor suppression Cell 75 1993 817 825
2. S. Waga, G.J. Hannon, and D. Beach The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA Nature 369 1994 574 578
3. J.M. Jung, J.M. Bruner, and S. Ruan Increased levels of p21 (WAF1/Cip1) in human brain tumors Oncogene 11 1995 2021 2028
4. S. Ruan, G. Fuller, and V. Levin Detection of p21 WAF1/Cip1 in brain metastases J. Neurooncol. 37 1998 223 228
5. S. Ruan, M.F. Okcu, and R.C. Pong Attenuation of WAF1/Cip1 expression by an antisense adenovirus expression vector sensitizes glioblastoma cells to apoptosis induced by chemotherapeutic agents 1,3-bis(2-chloroethyl)-1- nitrosourea and cisplatin Clin. Cancer Res. 5 1999 197 202
6. W. Zhang, L. Grasso, and C.D. McClain p53-independent induction of WAF1/Cip1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation Cancer Res. 55 1995 668 674
7. S.B. Parker, G. Eichele, and P. Zhang p53-independent expression of p21 Cip1 in muscle and other terminally differentiating cells Science 267 1995 1024 1027
8. W. Poluha, D.K. Poluha, and B. Chang The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells Mol. Cell. Biol. 16 1996 1335 1341
9. P.V. Kaye, J. Hapgood, and R.P. Millar Absence of mutations in exon 3 of the GnRH receptor in human gonadotroph adenomas Clin. Endocrinol. 47 1997 549 554
10. A.S. Suhardja, K.T. Kovacs, and J.T. Rutka Molecular pathogenesis of pituitary adenomas: a review Acta Neurochir. 141 1999 729 736
11. K. Yoshimoto, C. Tanaka, and S. Yamada Infrequent mutations of p16INK4A and p15INK4B genes in human pituitary adenomas Eur. J. Endocrinol. 136 1997 74 80
12. N.M. Oyesiku, C.O. Evans, and M.R. Brown Pituitary adenomas: screening for G alpha q mutations J. Clin. Endocrinol. Metab. 82 1997 4184 4188
13. Z. Zhuang, S.Z. Ezzat, and A.O. Vortmeyer Mutations of the MEN1 tumor suppressor gene in pituitary tumors Cancer Res. 57 1997 5446 5451
14. A. Levy, L. Hall, and W.A. Yeudall p53 gene mutations in pituitary adenomas: rare events Clin. Endocrinol. 41 1994 809 814
15. D.S. Franklin, V.L. Godfrey, and D.A. O'Brien Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity Mol. Cell. Biol. 20 2000 6147 6158
16. M. Suliman, J. Royds, and D. Cullen Mdm2 and the p53 pathway in human pituitary adenomas Clin. Endocrinol. 54 2001 317 325
17. H. Hiyama, O. Kubo, and T. Kawamata Experimental research, expression of cyclin kinase inhibitor p21/WAF1 protein in pituitary adenomas: correlations with endocrine activity, but not cell proliferation Acta Neurochir. 144 2002 481 488
18. T. Abe, N. Sanno, and Y.R. Osamura Proliferative potential in pituitary adenomas: measurement by monoclonal antibody MIB-1 Acta Neurochir. 139 1997 613 618
19. M. Shibuya, F. Saito, and T. Miwa Histochemical study of pituitary adenomas with Ki-67 and anti-DNA polymerase alpha monoclonal antibodies, bromodeoxyuridine labeling, and nucleolar organizer region counts Acta Neuropathol. 84 1992 178 183
20. L. Mastronardi, A. Guiducci, and C. Spera Ki-67 labelling index and invasiveness among anterior pituitary adenomas: analysis of 103 cases using the MIB-1 monoclonal antibody J. Clin. Pathol. 52 1999 107 111
21. K. Thapar, K. Kovacs, and B.W. Scheithauer Proliferative activity and invasiveness among pituitary adenomas and carcinomas: an analysis using the MIB-1 antibody Neurosurgery 38 1996 99 106
22. D. Zhao, Y. Tomono, and T. Nose Expression of p27kip1 and Ki-67 in pituitary adenomas: an investigation of marker of adenoma invasiveness Acta Neurochir. 141 1999 187 192
23. H. Ikeda, T. Yoshimoto, and N. Shida Molecular analysis of p21 and p27 genes in human pituitary adenomas Br. J. Cancer 76 1997 1119 1123