Continuous but not intermittent olanzapine infusion induces vacuous chewing movements in rats

Biological Psychiatry

Volumn 57, Issue 4, 2005, Pages 406-411

  Turrone, Peter ^b,c   Remington, Gary ^a,b,c   Kapur, Shitij ^a,b,c   Nobrega, José N ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

Author keywords

Antipsychotics; D2 receptor occupancy; Olanzapine; Vacuous chewing movements

Indexed keywords

DOPAMINE 2 RECEPTOR; HALOPERIDOL; OLANZAPINE; RACLOPRIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; EX VIVO STUDY; INFUSION; INFUSION PUMP; MALE; MASTICATION; NONHUMAN; PRIORITY JOURNAL;

EID: 13444283624     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2004.10.023     Document Type: Article

References (38)

1. F.J. Ayd Drug holidays intermittent pharmacology for psychiatric patients International Drug Therapy Newsletter 8 1966 1 3
2. C.M. Beasley, M.A. Dellva, R.N. Tamura, H. Morgenstern, W.M. Glazer, K. Ferguson, G.D. Tollefson Randomised double-blind comparison of the incidence of tardive dyskinesia in patients with schizophrenia during long-term treatment with olanzapine or haloperidol Br J Psychiatry 174 1999 23 30
3. G. Chouinard, L. Annable, A. Ross-Chouinard, P. Mercier A 5-year prospective longitundinal study of tardive dyskinesia Factors predicting appearance of new cases J Clin Psychopharmacol 8 suppl 4 1988 21S 28S
4. M.F. Egan, Y. Hurd, J. Ferguson, S.E. Bachus, E.H. Hamid, T.M. Hyde Pharmacological and neurochemical differences between acute and tardive vacuous chewing movements induced by haloperidol Psychopharmacology 127 1996 337 345
5. T.M. Engber, Z. Susel, J.L. Juncos, T.N. Chase Continuous and intermittent levodopa differentially affect rotation induced by D1 and D2 dopamine agonists Eur J Pharmacol 168 1989 291 298
6. L. Farde, A.L. Nordstrom, F.A. Wiesel, S. Pauli, C. Halldin, G. Sedvall Positron emission tomographic analysis of central D1 and D2 dopamine occupancy in patients treated with classical neuroleptics and clozapine Relation to extrapyramidal side effects Arch Gen Psychiatry 49 1992 538 544
7. A.L. Gibson Effect of drug holidays on tardive dyskinesia. E. Usdin I.S. Forrest Phenothiazines and Structurally Related Drugs Basic and Clinical Studies 1980 Elsevier-North Holland New York 333 336
8. W.M. Glazer Extrapyramidal side effects, tardive dykinesia, and the concept of atypicality J Clin Psychiatry 61 suppl 3 2000 16 21
9. B. Glenthoj Persistent vacuous chewing movements in rats following neuroleptic treatment Relationship with dopaminergic and cholinergic function Psychopharmacology 113 1993 157 166
10. B. Glenthoj, R. Hemmingsen Intermittent neuroleptic treatment induces long-lasting abnormal mouthing in the rat Eur J Pharmacol 164 1989 393 396
11. B. Glenthoj, R. Hemmingsen, P. Allerup, T.G. Bodwig Intermittent versus continuous neuroleptic treatment in a rat model Eur J Pharmacol 190 1990 275 286
12. M.B. Goldman, D.J. Luchins Intermittent neuroleptic therapy and tardive dyskinesia a literature review Hosp Community Psychiatry 35 1984 1215 1219
13. T. Hashimoto, D.E. Ross, X.M. Gao, D.R. Medoff, C.A. Tamminga Mixture in the distribution of haloperidol-induced oral dyskinesias in the rat supports an amimal model of tardive dyskinesia Psychopharmacology 137 1998 107 112
14. D.V. Jeste, M.P. Caligiuri Tardive dyskinesia Schizophr Bull 19 1993 303 315
15. J.M. Kane, M. Woerner, M. Borenstein, J. Wegner, J. Lieberman Integrating incidence and prevalence of tardive dyskinesia Psychopharmacol Bull 22 1986 254 258
16. S. Kapur, R.A. McClelland, S.C. VanderSpek, M.L. Wadenburg, G. Baker, J. Nobrega Increasing D2 affinity results in the loss of clozapine's atypical antipsychotic action Neuroreport 13 2002 831 835
17. S. Kapur, G. Remington Dopamine D2 receptors and their role in atypical antipsychotic action Still necessary and may even be sufficient Biol Psychiatry 50 2001 873 883
18. S. Kapur, P. Seeman Does fast dissociation from the dopamine D2 receptor explain the action of atypical antipsychotics? A new hypothesis Am J Psychiatry 158 2001 360 369
19. S. Kapur, S.C. VanderSpek, B.A. Brownlee, J.N. Nobrega Antipsychotic dosing in preclinical models is often unrepresentative of the clinical situation A suggested solution based on in vivo occupancy J Pharmacol Exp Ther 305 2003 1 7
20. S. Kapur, R. Zipursky, C. Jones, G. Remington, S. Houle Relationship between dopamine D2 occupancy, clinical response, and side effects A double-blind PET study of first-episode schizophrenia Am J Psychiatry 157 2000 514 520
21. S. Kapur, R. Zipursky, C. Jones, C.S. Shammi, G. Remington, P. Seeman A positron emission tomography study of quetiapine in schizophrenia A preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy Arch Gen Psychiatry 57 2000 553 559
22. S. Kapur, R. Zipursky, G. Remington Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia Am J Psychiatry 156 1999 286 293
23. H. Meltzer The role of serotonin in antipsychotic drug action Neuropsychopharmacology 21 1999 106S 115S
24. S. Mukherjee, M. Rosen, C. Cardenas, V. Varia, S. Olarte Tardive dyskinesia in outpatients Arch Gen Psychiatry 39 1982 466 469
25. K.M. Nielsen, J.J. Soghomonian Dual effects of intermittent or continuous L-DOPA administration on gene expression in the globus pallidus and subthalamic nucleus of adult rats with a unilateral 6-OHDA lesion Synapse 49 2003 246 260
26. P. O'Hara, T.S. Brugha, A. Lesage, J. Wing New findings on tardive dyskinesia in a community sample Psychol Med 23 1993 453 465
27. N.M.J. Rupniak, P. Jenner, C.D. Marsden Pharmacological characteristics of spontaneous or drug-associated purposeless chewing movements in rats Psychopharmacology 85 1985 71 79
28. C.F. Saller, M.J. Czupryna, A.I. Salama 5-HT2 receptor blockade by ICI 169,369 and other 5-HT2 antagonists modulates the effects of D2 dopamine receptor blockade J Pharmacol Exp Ther 253 1990 1162 1170
29. A.N. Samara, Y. Li, T.E. Robinson The rate of intravenous cocaine administration determines susceptibility to sensitization J Neurosci 22 2002 3244 3250
30. R.E. Steinpreis, H.J. Kaczmarek, A. Harrington The effects of raclopride on vacuous chewing movements in rats following acute administration Physiol Behav 60 1996 253 256
31. D. Tarsy, R.J. Baldassarini, F.I. Tarazi Effects of newer antipsychotics on extrapyramidal function CNS Drugs 16 2002 23 45
32. J. Tauscher, C. Jones, G. Remington, R.B. Zipursky, S. Kapur Significant dissociation of brain and plasma kinetics with antipsychotics Mol Psychiatry 7 2002 317 321
33. J. Tauscher, S. Kapur Choosing the right dose of antipsychotics in schizophrenia Lessons from neuroimaging studies CNS Drugs 15 2001 671 678
34. P. Turrone, G. Remington, S. Kapur, J.N. Nobrega Differential effects of within-day continuous versus transient D2 receptor occupancy in the development of vacuous chewing movements (VCMs) in rats Neuropsychopharmacology 28 2003 1433 1439
35. P. Turrone, G. Remington, J.N. Nobrega The vacuous chewing movement (VCM) model of tardive dyskinesia revisited Relationship to D2 receptor occupancy Neurosci Biobehav Rev 26 2002 361 380
36. P.N. Van Harten, H.W. Hoek, G.E. Matroos, R.S. Kahn Intermittent neuroleptic treatment and risk for tardive dyskinesia Curacao extrapyramidal syndromes study III Am J Psychiatry 155 1998 565 567
37. M.G. Woerner, J.M.J. Alvir, B.L. Saltz, J.A. Lieberman, J.M. Kane Prospective study of tardive dyskinesia in the elderly Rates and risk factors Am J Psychiatry 55 1998 1521 1528
38. R. Yassa, N.P. Nair, H. Iskandar, G. Schwartz Factors in the development of severe forms of tardive dyskinesia Am J Psychiatry 147 1990 1156 1163