Erythromycin exerts in vivo anti-inflammatory activity downregulating cell adhesion molecule expression

British Journal of Pharmacology

Volumn 144, Issue 2, 2005, Pages 190-201

  Sanz, María Jesús ^a   Abu Nabah, Yafa Naim ^a   Cerdá Nicolás, Miguel ^a   O'Connor, José Enrique ^a   Issekutz, Andrew C ^b   Cortijo, Julio ^a,c   Morcillo, Esteban J ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b DALHOUSIE UNIVERSITY   (Canada)

^c HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA   (Spain)

Author keywords

Cell adhesion molecules; Endothelium; Erythromycin; Intravital microscopy; Leukocyte; Lipopolysaccharide

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD11B ANTIGEN; CD18 ANTIGEN; CELL ADHESION MOLECULE; ELASTASE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ERYTHROMYCIN; INTERCELLULAR ADHESION MOLECULE 1; MACROLIDE; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; MYELOPEROXIDASE; PADGEM PROTEIN; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; LEUKOCYTE ROLLING; LUNG LAVAGE; MALE; MESENTERY; NEUTROPHIL; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL ADHESION MOLECULES; DOWN-REGULATION; ERYTHROMYCIN; GENE EXPRESSION REGULATION; INFLAMMATION; MALE; NEUTROPHIL INFILTRATION; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 13444283445     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706021     Document Type: Article

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