Generation and characterization of a novel adhesion function blocking monoclonal antibody recognizing both rat and mouse E-selectin

Hybridoma

Volumn 16, Issue 4, 1997, Pages 355-361

  Walter, Ulrike M ^a   Ayer, Linda M ^a   Manning, Anthony M ^b,c   Frenette, Paul S ^d   Wagner, Denisa D ^d   Hynes, Richard O ^e   Wolitzky, Barry A ^f   Issekutz, Andrew C ^a,g  

^a DALHOUSIE UNIVERSITY   (Canada)

^b PFIZER INC   (United States)

^c CELGENE CORPORATION   (United States)

^d CENTER FOR BLOOD RESEARCH   (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^f HOFFMANN LA ROCHE INC   (United States)

^g IWK HEALTH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; L SELECTIN; MONOCLONAL ANTIBODY;

ANTIGEN ANTIBODY COMPLEX; ANTIGEN RECOGNITION; ARTICLE; CELL STRAIN HL 60; CHO CELL; CROSS REACTION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATORY INFILTRATE; LEUKOCYTE ACTIVATION; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

CRICETINAE; CRICETULUS GRISEUS; RODENTIA;

EID: 0030752159     PISSN: 0272457X     EISSN: None     Source Type: Journal    
DOI: 10.1089/hyb.1997.16.355     Document Type: Article

References (29)

1. Bevilacqua MP, Pober JS, Mendrick DL, Cotran RS, and Gimbrone MAJ: Identification of an inducible endothelial-leukocyte adhesion molecule. Proc Natl Acad Sci USA 1987;84:9238-9243.
2. Bevilacqua MP, Stengelin S, Gimbrone MA, and Seed B: Endothelial leukocyte adhesion molecule 1: An inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science 1989;243:1160-1164.
3. Kyan-Aung U, Haskard DO, Poston RN, Thornhill MH, and Lee TH: Endothelial leukocyte adhesion molecule-1 and intercellular adhesion molecule-1 mediate the adhesion of eosinophils to endothelial cells in vitro and are expressed by endothelium in allergic cutaneous inflammation in vivo. J Immunol 1991;146:521-528.
4. Bochner BS, Luskinskas FW, Gimbrone AJ, Newman W, Sterbinsky SA, Derse-Anthony CP, Klunk D, and Schleimer RP: Adhesion of human basophils, eosinophils and neutrophils to IL-1 activated human vascular endothelial cells: Contributions of endothelial cell adhesion molecules. J Exp Med 1991;173:1553-1556.
5. Carlos T, Kovach N, Schwartz B, Rosa M, Newman B, Wayner E, Benjamin C, Osborne L, Lobb R, and Harlan J: Human monocytes bind to two cytokine-induced adhesive ligands on cultured human endothelial cells: Endothelial-leukocyte adhesion molecule-1 and vascular cell adhesion molecule-1. Blood 1991;77:2266-2271.
6. Picker LJ, Kishomoto TK, Smith CW, Warnock RA, and Butcher EC: ELAM-1 is an adhesion molecule for skin-homing T cells. Nature Lond 1991;349:796-799.
7. Lauri D, Needham L, Martin-Padura I, and Dejana E: Tumor cell adhesion to endothelial cells: Endothelial leukocyte adhesion molecule-1 as an inducible adhesive receptor specific for colon carcinoma cells. J Natl Cancer Inst 1991;83:1321-1324.
8. Tedder TF, Steeber DA, Chen A, and Engel P: The selectins: Vascular adhesion molecules. Faseb J 1995;9:866-873.
9. Cotran RS, Gimbrone MA, Bevilacqua MP, Mendrick DL, and Pober JS: Induction and detection of a human endothelial activation antigen in vivo. J Exp Med 1986;164:661-666.
10. Koch AE, Burrows JC, Haines GK, Carlos TM, Harlan JM, and Leibovich SJ: Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues. Lab Invest 1991;64:313-320.
11. Koizumi M, King N, Lobb R, Benjamin C, and Podolsky DK: Expression of vascular adhesion molecules in inflammatory bowel disease. Gastroenterology 1992;103:840-847.
12. Mulligan MS, Varani J, Dame MK, Lane CL, Smith CW, Anderson DC, and Ward PA: Role of endothelial-leukocyte adhesion molecule1 (ELAM-1) in neutrophil-mediated lung injury in rats. J Clin Invest 1991;88:1396-1406.
13. Ulich TR, Howard SC, Remick DG, Yi ES, Collins T, Guo K, Yin S, Keene JL, Schmuke JJ, Steininger CN, Welply JK, and Williams JH: Intratracheal administration of endotoxin and cytokines: VIII. LPS induces E-selectin expression; Anti-E-selectin and soluble E-selectin inhibit acute inflammation. Inflammation 1994;18:389-398.
14. Billups KL, Sherley JL, Palladino MA, Tindall JWM, and Roberts KP: Evidence for E-selectin complement regulatory domain mRNA splice variants in the rat. J Lab Clin Med 1995;126:580-587.
15. Norton CR, Rumberger JM, Burns DK, and Wolitzky BA: Characterization of murine E-selectin expression in vitro using novel anti-mouse E-selectin monoclonal antibodies. Biochem Biophys Res Commun 1993;195:250-258.
16. Erbe DV, Wolitzky B A, Presta LG, Norton CR, Ramos RJ, Burns DK, Rumberger JM, Rao BNN, Foxall C, Brandley BK, and Lasky LA: Identification of an E-selectin region critical for carbohydrate recognition and cell adhesion. J Cell Biol 1992;119:215-227.
17. Zhang RL, Chopp M, Phillips LM, Rosenbloom CL, Cruz R, and Manning AM: E-selectin in the pathogenesis of focal cerebral ischemia and reperfusion in the rat. J Cereb Blood FLow Metab (in press).
18. Frenett PS, Mayadas TN, Rayburn H, Hynes RO, and Wagner DD: Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins. Cell 1996;84:563-574.
19. Köhler G, and Milstein C: Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975;256:495-497.
20. Yokoyama WM: Production of monoclonal antibodies. In: Current Protocols in Immunology, JE Coligan, AM Kruisbeek, DH Margulies, EM Shevach, and W Strober (Eds.). John Wiley & Sons, NY, 1991, pp. 2.5.1-2.5.12.
21. Spangenberg P, Redlich H, Bergmann I, Lösche W, Götzrath M, and Kehrel B: The platelet glycoprotein IIb/IIa complex is involved in the adhesion of activated platelets to leukocytes. Thromb Haemostas 1993;70:514-521.
22. Li SH, Burns DK, Rumberger JM, Presky DH, Wilkinson VL, Anostario M, Wolitzky BA, Norton CR, Familletti PC, Kim KJ, Goldstein AL, Cox DC, and Huang K-S: Consensus repeat domains of E-selectin enhance ligand binding. J Biol Chem 1994;269:4431-4437.
23. Issekutz AC, and Issekutz TB: The contribution of LFA-1 (CD11a/CD18) and MAC-1 (CD11b/CD18) to the in vivo migration of polymorphonuclear leucocytes to inflammatory reactions in the rat. Immunology 1992;76:655-661.
24. Stroud MR, Handa K, Salyan MEK, Ito K, Levery SB, Hakomori S, Reinhold BB, and Reinhold VN: Monosialogangliosides of human myelogenous leukemia HL60 cells and normal human leukocytes: 1. Separation of E-selectin binding from nonbinding gangliosides, and absence of sialosyl-Lex having tetraosyl to octaosyl core. Biochem 1996;35:758-769.
25. Lenter M, Levinovitz A, Isenmann S, and Vestweber D: Monospecific and common glycoprotein ligands for E- and P-Selectin on myeloid cells. J Cell Biol 1994;125:471-481.
26. Patel KD, Moore KL, Nollert MU, and McEver RP: Neutrophils use both shared and distinct mechanisms to adhere to selectins under static and flow conditions. J Clin Invest 1995;96:1887-1896.
27. Berg EL, Fromm C, Melrose J, and Tsurushita N: Antibodies cross-reactive with E- and P-selectin block both E- and P-selectin functions. Blood 1995;85:31-37.
28. Misugi E, Kawamura N, Imanishi N, Tojo SJ, and Morooka S: Sialyl Lewis X moiety on rat polymorphonuclear leukocytes responsible for binding to rat E-selectin. Biochem Biophys Res Commun 1995;215:547-554.
29. Walter UM, Ayer LM, Wolitzky BA, Wagner DD, Hynes RO, Manning AM, and Issekutz AC. Characterization of a novel adhesion function blocking monoclonal antibody to rat/mouse P-selectin generated in the P-selectin deficient mouse. Hybridoma 1997;16:249-257.