Hypersensitivity to ovalbumin induces chronic intestinal dysmotility and increases the number of intestinal mast cells

Neurogastroenterology and Motility

Volumn 17, Issue 1, 2005, Pages 112-122

  Saavedra, Y ^a   Vergara, Patri ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Hypersensitivity; Intestinal motility; Irritable bowel syndrome; Mucosal mast cells; Rat mast cell protease II

Indexed keywords

CHYMASE; IMMUNOGLOBULIN E; OVALBUMIN; RAT MAST CELL PROTEASE 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BORDETELLA PERTUSSIS; CELL ACTIVATION; CLINICAL PROTOCOL; CONTROLLED STUDY; DUODENUM; FOOD ALLERGY; IMMUNOGLOBULIN BLOOD LEVEL; IN VITRO STUDY; INTESTINE MOTILITY; IRRITABLE COLON; MALE; MAST CELL; MOTOR DYSFUNCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTAKE; PROVOCATION TEST; RAT; SENSITIZATION;

ANIMALS; BORDETELLA PERTUSSIS; CHOLECYSTOKININ; DUODENUM; FOOD HYPERSENSITIVITY; GASTROINTESTINAL MOTILITY; ILEUM; IMMUNOGLOBULIN E; IMMUNOHISTOCHEMISTRY; INTESTINAL DISEASES; INTESTINAL MUCOSA; INTESTINE, SMALL; MALE; MAST CELLS; MUSCLE TONUS; OVALBUMIN; RATS; RATS, SPRAGUE-DAWLEY; SERINE ENDOPEPTIDASES;

EID: 13444270900     PISSN: 13501925     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2004.00597.x     Document Type: Article

References (33)

1. Locke CR, Zinsmeister AR, Talley NJ, Fett SL, Melton LJ. Risk factors for irritable bowel syndrome: role of analgesics and food sensitivities. Am J Gastroenterol 2000; 95: 157-65.
2. Vermillion DL, Ernst PB, Sciccchitano R, Collins SM. Antigen-induced contraction of jejunal smooth muscle in the sensitized rat. Am J Physiol 1988; 255: G701-08.
3. Barbara G, Vallance BA, Collins SM. Persistent intestinal neuromuscular dysfunction after acute nematode infection in mice. Gastroenterology 1997; 113: 1224-32.
4. De Giorgio R, Barbara G, Blennerhassett P et al. Intestinal inflammation and activation of sensory nerve pathways: a functional and morphological study in the nematode infected rat. Gut 2001; 49: 822-27.
5. Stead RH, Tomioka M, Quinonez G, Simon GT, Felten SY, Bienenstock J. Intestinal mucosal mast cells in normal and nematode-infected rat intestines are in intimate contact with peptidergic nerves. Proc Natl Acad Sci 1987; 84: 2975-79.
6. Castro GA, Harari Y, Russell D. Mediators of anaphylaxis-induced ion transport changes in small intestine. Am J Physiol 1987; 253: G540-48.
7. Cooke HJ. Neuroimmune signaling in regulation of intestinal ion transport. Am J Physiol 1994; 266: G167-78.
8. Wang YZ, Palmer JM, Cooke HJ. Neuroimmune regulation of colonic secretion in guinea pig. Am J Physiol 1991; 260: G307-14.
9. Scott RB, Gall DG, Maric M. Mediation of food protein-induced jejunal smooth muscle contraction in sensitized rats. Am J Physiol 1990; 259: G6-14.
10. Crowe SE, Soda K, Stanisz AM, Perdue MH. Intestinal permeability in allergic rats: nerve involvement in antigen-induced changes. Am J Physiol 1993; 264: G617-23.
11. Curtis GH, Patrick MK, Catto-Smith AG, Gall DG. Intestinal anaphylaxis in the rat. Effect of chronic antigen exposure. Gastroenterology 1990; 98: 1558-66.
12. Turner MW, Barnett GE, Strobel S. Mucosal mast cell activation patterns in the rat following repeated feeding of antigen. Clin Exp Allergy 1990; 20: 421-27.
13. Bazin H, Platteau B. Production of circulating reaginic (IgE) antibodies by oral administration of ovalbumin to rats. Immunology 1976; 30: 679-84.
14. Knippels LMJ, Penninks AH, Smit JJ, Houben GF. Immune-mediated effects upon oral challenge of ovalbumin-sensitized Brown Norway rats: further characterization of a rat food allergy model. Toxicol Appl Pharmacol 1999; 156: 161-69.
15. Scott RB, Diamant SC, Gall DG. Motility effects of intestinal anaphylaxis in the rat. Am J Physiol 1988; 255: G505-11.
16. Scott RB, Tan DTM. Mediation of altered motility in food protein induced intestinal anaphylaxis in Hooded Lister rat. Can J Physiol Pharmacol 1996; 74: 320-30.
17. Scott RB, Tan DTM, Miampamba M, Sharkey KA. Anaphylaxis-induced alterations in intestinal motility: role of extrinsic neural pathways. Am J Physiol 1998; 275: G812-21.
18. Saavedra Y, Vergara P, Ovalbumin sensitization induces intestinal chronic motor alterations in rats. Neurogastroenterol Motil 2003; 15(5): 79 (A203).
19. Knippels LMJ, Penninks AH, Spanhaak S, Houben GF. Oral sensitization to food proteins: a Brown Norway rat model. Clin Exp Allergy 1998; 28: 368-75.
20. Harvey RF, Read AE. Effect of cholecystokinin on colonic motility and symptoms in patients with the irritable-bowel syndrome. Lancet 1973; 7793: 1-3.
21. Giralt M, Vergara P. Inhibition by CCK of ascending contraction elicited by mucosal stimulation in the duodenum of the rat. Neurogastroenterol Motil 2000; 12: 173-80.
22. Torrents D, Vergara P. In vivo changes in the intestinal reflexes and the response to CCK in the inflamed small intestine of the rat. Am J Physiol 2000; 279: G543-51.
23. Juanola C, Giralt M, Jiménez M, Mourelle M, Vergara P. Mucosal mast cells are involved in CCK disruption of MMC in the rat intestine. Am. J Physiol 1998; 275: G63-67.
24. Vergara P, Saavedra Y, Juanola C. Neuroendocrine control of intestinal mucosal mast cells under physiological conditions. Neurogastroenterol Motil 2002; 14: 1-8.
25. Helm RM. Food allergy animal models. An overview. Ann NY Acad Sci 2002; 964: 139-50.
26. Bischoff SC, Mayer JH, Manns MP. Allergy and the gut. Int Arch Allergy Immunol 2000; 121: 270-83.
27. Frieling T, Cooke HJ, Wood JD. Neuroimmune communication in the submucous plexus of guinea pig colon after sensitization to milk antigen. Am J Physiol 1994; 267: 1087-93.
28. Frieling T, Parmer JM, Cooke HJ, Wood JD. Neuroimmune communication in the submucous plexus of guinea pig colon after infection with Trichinella spiralis. Gastroenterology 1994; 107: 1602-09.
29. Liu S, Hu HZ, Gao N et al. Neuroimmune interactions in guinea pig stomach and small intestine. Am J Physiol 2003; 284: 154-64.
30. Cooke HJ, Wang YZ, Rogers R. Mechanisms of neural-immune system interactions. Dig Dis Sci 1992; 37: 966 (A-4).
31. 2-receptors in myoelectric activity of small bowel in the dog. Am J Physiol 1980; 238: G50-6.
32. Giralt M, Vergara P. Both afferent and efferent nerves are implicated in cholecystokinin motor actions in the small intestine of the rat. Regul Pepti 1999; 81: 73-80.
33. Torrents D, Torres R, De Mora F, Vergara P. Antinerve growth factor treatment prevents intestinal dysmotility in Trichinella spiralis-iniected rats, J Pharmacol Exp Ther 2002; 302: 659-65.