Tetraplegic subjects have hyperleptinaemia with marked circadian variation

Clinical Endocrinology

Volumn 62, Issue 2, 2005, Pages 223-227

  Hjeltnes, Nils ^a   De Groot, Patricia ^b   Birkeland, Kåre I ^c   Falch, Jan A ^c   Iversen, Per O ^d  

^a SUNNAAS REHABILITATION HOSPITAL   (Norway)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c AKER UNIVERSITY HOSPITAL   (Norway)

^d UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN;

ADIPOCYTE; ADULT; ARTICLE; BODY COMPOSITION; BONE REMODELING; CALORIC INTAKE; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CONTROLLED STUDY; ENERGY EXPENDITURE; ENERGY METABOLISM; HUMAN; HYPERLEPTINEMIA; MALE; METABOLIC SYNDROME X; OSTEOPOROSIS; PRIORITY JOURNAL; QUADRIPLEGIA; SIGNAL TRANSDUCTION; SPINAL CORD LESION; SYMPATHETIC NERVE CELL; THERMOGENESIS;

ADULT; BODY COMPOSITION; CASE-CONTROL STUDIES; CIRCADIAN RHYTHM; HUMANS; LEPTIN; MALE; METABOLIC SYNDROME X; OSTEOPOROSIS; QUADRIPLEGIA; RISK;

EID: 13444252916     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2005.02204.x     Document Type: Article

References (36)

1. Garland, D.E., Stewart, C.A., Adkins, R.H., Hu, S.S., Rosen, C, Liotta, F.J. & Weinstein, D.A. (1992) Osteoporosis after spinal cord injury. Journal of Orthopedic Research, 10, 371-378.
2. Greenway, R.M., Houser, H.B., Lindan, O. & Weir, D.R. (1970) Long-term changes in gross body composition of paraplegic and quadriplegic patients. Paraplegia, 7, 301-318.
3. Bergmann, P., Heilporn, A., Schoutens, A., Paternot, J. & Tricot, A. (1977) Longitudinal study of calcium and bone metabolism in paraplegic patients. Paraplegia, 15, 147-159.
4. Janssen, T.W., van Oers, C.A., van Kamp, G.J., TenVoorde, B.J., van der Woude, L.H. & Hollander, A.P. (1997) Coronary heart disease risk indicators, aerobic power, and physical activity in men with spinal cord injuries. Archives of Physical and Medical Rehabilitation, 78, 697-705.
5. Mathias, C.J., Christensen, N.J., Corbett, J.L., Frankel, H.L. & Spalding, J.M. (1976) Plasma catecholamines during paroxysmal neurogenic hypertension in quadriplegic man. Circulation Research, 39, 204-208.
6. Karlsson, A.K., Attvall, S., Jansson, P.A., Sullivan, L. & Lonnroth, P. (1995) Influence of the sympathetic nervous system on insulin sensitivity and adipose tissue metabolism: a study in spinal cord-injured subjects. Metabolism, 44, 52-58.
7. Hjeltnes, N. & Wallberg-Henriksson, H. (1998) Improved work capacity but unchanged peak oxygen uptake during primary rehabilitation in tetraplegic patients. Spinal Cord, 36, 691-698.
8. Rayner, D.V. & Trayhurn, P. (2001) Regulation of leptin production: sympathetic nervous system interactions. Journal of Molecular Medicine, 79, 8-20.
9. Commins, S.P., Marsh, D.J., Thomas, S.A., Watson, P.M., Padgett, M.A., Palmiter, R. & Gettys, T.W. (1999) Norepinephrine is required for leptin effects on gene expression in brown and white adipose tissue. Endocrinology, 140, 4772-4778.
10. Sivitz, W.I., Fink, B.D., Morgan, D.A., Fox, J.M., Donohoue, P.A. & Haynes, W.G. (1999) Sympathetic inhibition, leptin, and uncoupling protein subtype expression in normal fasting rats. American Journal of Physiology, 277, E668-E677.
11. Nitsche, B., Perschak, H., Curt, A. & Dietz, V. (1996) Loss of circadian blood pressure variability in complete tetraplegia. Journal of Human Hypertension, 10, 311-317.
12. Iversen, P.O., Groot, P.D., Hjeltnes, N., Andersen, T.O., Mowinckel, M.C. & Sandset, P.M. (2002) Impaired circadian variations of haemostatic and fibrinolytic parameters in tetraplegia. British Journal of Haematology, 119, 1011-1016.
13. Yamazaki, S., Numano, R., Abe, M., Hida, A., Takahashi, R., Ueda, M., Block, G.D., Sakaki, Y., Menaker, M. & Tei, H. (2000) Resetting central and peripheral circadian oscillators in transgenic rats. Science, 288, 682-685.
14. Arasaradnam, M.P., Morgan, L., Wright, J. & Gama, R. (2002) Diurnal variation in lipoprotein lipase activity. Annals of Clinical Biochemistry, 39, 136-139.
15. Boyne, M.S., Silver, D.M., Kaplan, J. & Saudek, C.D. (2003) Timing of changes in interstitial and venous blood glucose measured with a continuous subcutaneous glucose sensor. Diabetes, 52, 2790-2794.
16. Ditunno, J.F. Jr, Young, W., Donovan, W.H. & Creasey, G. (1994) The international standards booklet for neurological and functional classification of spinal cord injury. American Spinal Injury Association. Paraplegia, 32, 70-80.
17. Mazess, R.B., Barden, H.S., Bisek, J.P. & Hanson, J. (1990) Dual-energy x-ray absorptiometry for total-body and regional bone-mineral and soft-tissue composition. American Journal of Clinical Nutrition, 51, 1106-1112.
18. Spungen, A.M., Bauman, W.A., Wang, J. & Pierson, R.N. Jr. (1995) Measurement of body fat in individuals with tetraplegia: a comparison of eight clinical methods. Paraplegia, 33, 402-408.
19. Rishaug, U., Birkeland, K.I., Falch, J.A. & Vaaler, S. (1995) Bone mass in non-insulin-dependent diabetes mellitus. Scandinavian Journal of Clinical and Laboratory Investigation, 55, 257-262.
20. Jeon, J.Y., Steadward, R.D., Wheeler, G.D., Bell, G., McCargar, L. & Harber, V. (2003) Intact sympathetic nervous system is required for leptin effects on resting metabolic rate in people with spinal cord injury. Journal of Clinical Endocrinology and Metabolism, 88, 402-407.
21. Perusse, L, Collier, G., Gagnon, J., Leon, A.S., Rao, D.C., Skinner, J.S., Wilmore, J.H., Nadeau, A., Zimmet, P.Z. & Bouchard, C. (1997) Acute and chronic effects of exercise on leptin levels in humans. Journal of Applied Physiology, 83, 5-10.
22. Scelsi, R., Marchetti, C., Poggi, P., Lotta, S. & Lommi, G. (1982) Muscle fiber type morphology and distribution in paraplegic patients with traumatic cord lesion. Histochemical and ultrastructural aspects of rectus femoris muscle. Acta Neuropathologica, 57, 243-248.
23. Caro, J.F., Kolaczynski, J.W., Nyce, M.R., Ohannesian, J.P., Opentanova, I., Goldman, W.H., Lynn, R.B., Zhang, P.L., Sinha, M.K. & Considine, R.V. (1996) Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance. Lancet, 348, 159-161.
24. Aksnes, A.K., Brundin, T., Hjeltnes, N., Maehlum, S. & Wahren, J. (1993) Meal-induced rise in resting energy expenditure in patients with complete cervical spinal cord lesions. Paraplegia, 31, 462-472.
25. Krassioukov, A.V., Bunge, R.P., Pucket, W.R. & Bygrave, M.A. (1999) The changes in human spinal sympathetic preganglionic neurons after spinal cord injury. Spinal Cord, 37, 6-13.
26. Bini, V., Igli, B.C., Papi, E, Celi, E, Saggese, G. & Falorni, A. (2004) Relationships of serum leptin levels with biochemical markers of bone turnover and with growth factors in normal weight and overweight children. Hormone Research, 61, 170-175.
27. Wagner, R., Oberste-Berghaus, C., Herpertz, S., Blum, W.F., Pelz, B., Hebebrand, J., Senf, W., Mann, K. & Albers, N. (2000) Time relationship between circadian variation of serum levels of leptin, insulin and cortisol in healthy subjects. Hormone Research, 54, 174-180.
28. Simon, C., Gronfier, C., Schlienger, J.L. & Brandenberger, G. (1998) Circadian and ultradian variations of leptin in normal man under continuous enteral nutrition: relationship to sleep and body temperature. Journal of Clinical Endocrinology and Metabolism, 83, 1893-1899.
29. Aksnes, A.K., Brundin, T., Hjeltnes, N. & Wahren, J. (1994) Glucose-induced thermogenesis in tetraplegic patients with low sympathoadrenal activity. American Journal of Physiology, 266, E161-E170.
30. Hjeltnes, N., Fernstrom, M., Zierath, J.R. & Krook, A. (1999) Regulation of UCP2 and UCP3 by muscle disuse and physical activity in tetraplegic subjects. Diabetologia, 42, 826-830.
31. Schoeller, D.A., Cella, L.K., Sinha, M.K. & Caro, J.F. (1997) Entrainment of the diurnal rhythm of plasma leptin to meal timing. Journal of Clinical Investigation, 100, 1882-1887.
32. Takeda, S., Elefteriou, F., Levasseur, R., Liu, X., Zhao, L., Parker, K.L., Armstrong, D., Ducy, P. & Karsenty, G. (2002) Leptin regulates bone formation via the sympathetic nervous system. Cell, 111, 305-317.
33. Reseland, J.E., Syversen, U., Bakke, I., Qvigstad, G., Eide, L.G., Hjertner, O., Gordeladze, J.O. & Drevon, C.A. (2001) Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization. Journal of Bone and Mineral Research, 16, 1426-1433.
34. Kume, K., Satomura, K., Nishisho, S., Kitaoka, E., Yamanouchi, K., Tobiume, S. & Nagayama, M. (2002) Potential role of leptin in endochondral ossification. Journal of Histochemistry and Cytochemistry, 50, 159-169.
35. Bjarnason, N.H., Henriksen, E.E., Alexandersen, P., Christgau, S., Henriksen, D.B. & Christiansen, C. (2002) Mechanism of circadian variation in bone resorption. Bone, 30, 307-313.
36. Reseland, J.E., Anderssen, S.A., Solvoll, K., Hjermann, I., Urdal, P., Holme, I. & Drevon, C.A. (2001) Effect of long-term changes in diet and exercise on plasma leptin concentrations. American Journal of Clinical Nutrition, 73, 240-245.