-
1
-
-
0348111398
-
The role of endogenous heme synthesis and degradation domain cysteines in cellular iron-dependent degradation of IRP2
-
Bourdon, E., D. K. Kang, M. C. Ghosh, S. K. Drake, J. Wey, R. L. Levine, and T. A. Rouault. 2003. The role of endogenous heme synthesis and degradation domain cysteines in cellular iron-dependent degradation of IRP2. Blood Cells Mol. Dis. 31:247-255.
-
(2003)
Blood Cells Mol. Dis.
, vol.31
, pp. 247-255
-
-
Bourdon, E.1
Kang, D.K.2
Ghosh, M.C.3
Drake, S.K.4
Wey, J.5
Levine, R.L.6
Rouault, T.A.7
-
2
-
-
0032540274
-
Converse modulation of IRP-1 and IRP-2 by immunological stimuli in murine RAW 264.7 macrophages
-
Bouton, C., L. Oliveira, and J.-C. Drapier. 1998. Converse modulation of IRP-1 and IRP-2 by immunological stimuli in murine RAW 264.7 macrophages. J. Biol. Chem. 273:9403-9408.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9403-9408
-
-
Bouton, C.1
Oliveira, L.2
Drapier, J.-C.3
-
3
-
-
0029802591
-
p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
-
Chen, X., L. J. Ko, L. Jayaraman, and C. Prives. 1996. p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev. 10:2438-2451.
-
(1996)
Genes Dev.
, vol.10
, pp. 2438-2451
-
-
Chen, X.1
Ko, L.J.2
Jayaraman, L.3
Prives, C.4
-
4
-
-
0025788509
-
Generation of EPR-detectable nitrosyl-iron complexes in tumor target cells cocultured with activated macrophages
-
Drapier, J. C., C. Pellat, and Y. Henry. 1991. Generation of EPR-detectable nitrosyl-iron complexes in tumor target cells cocultured with activated macrophages. J. Biol. Chem. 266:10162-10167.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 10162-10167
-
-
Drapier, J.C.1
Pellat, C.2
Henry, Y.3
-
5
-
-
0025817680
-
The biochemical pathways of nitric oxide formation from nitrovasodilators: Appropriate choice of exogenous NO donors and aspects of preparation and handling of aqueous NO solutions
-
Feelisch, M. 1991. The biochemical pathways of nitric oxide formation from nitrovasodilators: appropriate choice of exogenous NO donors and aspects of preparation and handling of aqueous NO solutions. J. Cardiovasc. Pharmacol. 17(Suppl. 3):S25-S33.
-
(1991)
J. Cardiovasc. Pharmacol.
, vol.17
, Issue.SUPPL. 3
-
-
Feelisch, M.1
-
6
-
-
0032192140
-
The complexity of p53 modulation: Emerging patterns from divergent signals
-
Giaccia, A. J., and M. B. Kastan. 1998. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev. 12:2973-2983.
-
(1998)
Genes Dev.
, vol.12
, pp. 2973-2983
-
-
Giaccia, A.J.1
Kastan, M.B.2
-
7
-
-
0033538443
-
Activation of the cell death program by nitric oxide involves inhibition of the proteasome
-
Glockzin, S., A. von Knethen, M. Scheffner, and B. Brune. 1999. Activation of the cell death program by nitric oxide involves inhibition of the proteasome. J. Biol. Chem. 274:19581-19586.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19581-19586
-
-
Glockzin, S.1
Von Knethen, A.2
Scheffner, M.3
Brune, B.4
-
8
-
-
0028982262
-
Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome
-
Guo, B., J. D. Phillips, Y. Yu, and E. A. Leibold. 1995. Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome. J. Biol. Chem. 270:21645-21651.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21645-21651
-
-
Guo, B.1
Phillips, J.D.2
Yu, Y.3
Leibold, E.A.4
-
9
-
-
0026756095
-
Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: Role of the iron-sulfur cluster
-
Haile, D. J., T. A. Rouault, C. K. Tang, J. Chin, J. B. Harford, and R. D. Klausner. 1992. Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster. Proc. Natl. Acad. Sci. USA 89:7536-7540.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7536-7540
-
-
Haile, D.J.1
Rouault, T.A.2
Tang, C.K.3
Chin, J.4
Harford, J.B.5
Klausner, R.D.6
-
10
-
-
0141890273
-
Oxygen and iron regulation of iron regulatory protein 2
-
Hanson, E. S., M. L. Rawlins, and E. A. Leibold. 2003. Oxygen and iron regulation of iron regulatory protein 2. J. Biol. Chem. 278:40337-40342.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 40337-40342
-
-
Hanson, E.S.1
Rawlins, M.L.2
Leibold, E.A.3
-
11
-
-
2042546096
-
Balancing acts; molecular control of mammalian iron metabolism
-
Hentze, M. W., M. U. Muckenthaler, and N. C. Andrews. 2004. Balancing acts; molecular control of mammalian iron metabolism. Cell 117:285-297.
-
(2004)
Cell
, vol.117
, pp. 285-297
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Andrews, N.C.3
-
12
-
-
0019388174
-
Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: Evidence for the involvement of S-nitrosothiols as active intermediates
-
Ignarro, L. J., H. Lippton, J. C. Edwards, W. H. Baricos, A. L. Hyman, P. J. Kadowitz, and C. A. Gruetter. 1981. Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates. J. Pharmacol. Exp. Ther. 218:739-749.
-
(1981)
J. Pharmacol. Exp. Ther.
, vol.218
, pp. 739-749
-
-
Ignarro, L.J.1
Lippton, H.2
Edwards, J.C.3
Baricos, W.H.4
Hyman, A.L.5
Kadowitz, P.J.6
Gruetter, C.A.7
-
13
-
-
0028788316
-
Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2
-
Iwai, K., R. D. Klausner, and T. A. Rouault. 1995. Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2. EMBO J. 14:5350-5357.
-
(1995)
EMBO J.
, vol.14
, pp. 5350-5357
-
-
Iwai, K.1
Klausner, R.D.2
Rouault, T.A.3
-
14
-
-
0037108199
-
The labile iron pool: Characterization, measurement, and participation in cellular processes
-
Kakhlon, O., and Z. I. Cabantchik. 2002. The labile iron pool: characterization, measurement, and participation in cellular processes. Free Radic. Biol. Med. 33:1037-1046.
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 1037-1046
-
-
Kakhlon, O.1
Cabantchik, Z.I.2
-
15
-
-
0032746973
-
Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2
-
Kim, S., and P. Ponka. 1999. Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2. J. Biol. Chem. 274:33035-33042.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33035-33042
-
-
Kim, S.1
Ponka, P.2
-
16
-
-
0034089867
-
Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2
-
Kim, S., and P. Ponka. 2000. Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2. J. Biol. Chem. 275:6220-6226.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6220-6226
-
-
Kim, S.1
Ponka, P.2
-
17
-
-
0037125975
-
Nitrogen monoxide-mediated control of ferritin synthesis: Implications for macrophage iron homeostasis
-
Kim, S., and P. Ponka. 2002. Nitrogen monoxide-mediated control of ferritin synthesis: implications for macrophage iron homeostasis. Proc. Natl. Acad. Sci. USA 99:12214-12219.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12214-12219
-
-
Kim, S.1
Ponka, P.2
-
18
-
-
0347624596
-
S-nitrosylation of IRP2 regulates its stability via the ubiquitin-proteasome pathway
-
Kim, S., S. S. Wing, and P. Ponka. 2004. S-nitrosylation of IRP2 regulates its stability via the ubiquitin-proteasome pathway. Mol. Cell. Biol. 24:330-337.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 330-337
-
-
Kim, S.1
Wing, S.S.2
Ponka, P.3
-
19
-
-
0035138456
-
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
-
LaVaute, T., S. Smith, S. Cooperman, K. Iwai, W. Land, E. Meyron-Holtz, S. K. Drake, G. Miller, M. Abu-Asab, M. Tsokos, R. Switzer III, A. Grinberg, P. Love, N. Tresser, and T. A. Rouault. 2001. Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. Nat. Genet. 27:209-214.
-
(2001)
Nat. Genet.
, vol.27
, pp. 209-214
-
-
Lavaute, T.1
Smith, S.2
Cooperman, S.3
Iwai, K.4
Land, W.5
Meyron-Holtz, E.6
Drake, S.K.7
Miller, G.8
Abu-Asab, M.9
Tsokos, M.10
Switzer III, R.11
Grinberg, A.12
Love, P.13
Tresser, N.14
Rouault, T.A.15
-
20
-
-
10744223491
-
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
-
Meyron-Holtz, E. G., M. C. Ghosh, K. Iwai, T. LaVaute, X. Brazzolotto, U. V. Berger, W. Land, H. Ollivierre-Wilson, A. Grinberg, P. Love, and T. A. Rouault. 2004. Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis. EMBO J. 23:386-395.
-
(2004)
EMBO J.
, vol.23
, pp. 386-395
-
-
Meyron-Holtz, E.G.1
Ghosh, M.C.2
Iwai, K.3
Lavaute, T.4
Brazzolotto, X.5
Berger, U.V.6
Land, W.7
Ollivierre-Wilson, H.8
Grinberg, A.9
Love, P.10
Rouault, T.A.11
-
21
-
-
1842608845
-
Iron metabolism and the IRE/IRP regulatory system: An update
-
Pantopoulos, K. 2004. Iron metabolism and the IRE/IRP regulatory system: an update. Ann. N. Y. Acad. Sci. 1012:1-13.
-
(2004)
Ann. N. Y. Acad. Sci.
, vol.1012
, pp. 1-13
-
-
Pantopoulos, K.1
-
22
-
-
0028929741
-
Nitric oxide signaling to iron-regulatory protein (IRP): Direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts
-
Pantopoulos, K., and M. W. Hentze. 1995. Nitric oxide signaling to iron-regulatory protein (IRP): direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts. Proc. Natl. Acad. Sci. USA 92:1267-1271.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1267-1271
-
-
Pantopoulos, K.1
Hentze, M.W.2
-
23
-
-
0000901196
-
Nitric oxide, oxygen radicals and iron metabolism
-
L. Ignarro (ed.). Academic Press, San Diego, Calif.
-
Pantopoulos, K., and M. W. Hentze. 2000. Nitric oxide, oxygen radicals and iron metabolism, p. 293-313. In L. Ignarro (ed.), Nitric oxide. Academic Press, San Diego, Calif.
-
(2000)
Nitric Oxide
, pp. 293-313
-
-
Pantopoulos, K.1
Hentze, M.W.2
-
25
-
-
0029927715
-
Differential regulation of IRP-1 and IRP-2 by nitric oxide in rat hepatoma cells
-
Phillips, J. D., D. V. Kinikini, Y. Yu, B. Guo, and E. A. Leibold. 1996. Differential regulation of IRP-1 and IRP-2 by nitric oxide in rat hepatoma cells. Blood 87:2983-2992.
-
(1996)
Blood
, vol.87
, pp. 2983-2992
-
-
Phillips, J.D.1
Kinikini, D.V.2
Yu, Y.3
Guo, B.4
Leibold, E.A.5
-
26
-
-
0032006692
-
Nitric oxide-mediated induction of ferritin synthesis in J774 macrophages by inflammatory cytokines: Role of selective iron regulatory protein-2 downregulation
-
Recalcati, S., D. Taramelli, D. Conte, and G. Cairo. 1998. Nitric oxide-mediated induction of ferritin synthesis in J774 macrophages by inflammatory cytokines: role of selective iron regulatory protein-2 downregulation. Blood 91:1059-1066.
-
(1998)
Blood
, vol.91
, pp. 1059-1066
-
-
Recalcati, S.1
Taramelli, D.2
Conte, D.3
Cairo, G.4
-
27
-
-
1642458415
-
Iron-mediated degradation of IRP2: An unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity
-
Wang, J., G. Chen, M. Muckenthaler, B. Galy, M. W. Hentze, and K. Pantopoulos. 2004. Iron-mediated degradation of IRP2: an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity. Mol. Cell. Biol. 24:954-965.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 954-965
-
-
Wang, J.1
Chen, G.2
Muckenthaler, M.3
Galy, B.4
Hentze, M.W.5
Pantopoulos, K.6
-
28
-
-
0027184412
-
Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway
-
Weiss, G., B. Goossen, W. Doppler, D. Fuchs, K. Pantopoulos, G. Werner-Felmayer, H. Wachter, and M. W. Hentze. 1993. Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway. EMBO J. 12:3651-3657.
-
(1993)
EMBO J.
, vol.12
, pp. 3651-3657
-
-
Weiss, G.1
Goossen, B.2
Doppler, W.3
Fuchs, D.4
Pantopoulos, K.5
Werner-Felmayer, G.6
Wachter, H.7
Hentze, M.W.8
-
29
-
-
0141989227
-
Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2
-
Yamanaka, K., H. Ishikawa, Y. Megumi, F. Tokunaga, M. Kanie, T. A. Rouault, I. Morishima, N. Minato, K. Ishimori, and K. Iwai. 2003. Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2. Nat. Cell Biol. 5:336-340.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 336-340
-
-
Yamanaka, K.1
Ishikawa, H.2
Megumi, Y.3
Tokunaga, F.4
Kanie, M.5
Rouault, T.A.6
Morishima, I.7
Minato, N.8
Ishimori, K.9
Iwai, K.10
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