Prodigiosin Induces Apoptosis by Acting on Mitochondria in Human Lung Cancer Cells

Annals of the New York Academy of Sciences

Volumn 1010, Issue , 2003, Pages 178-181

  Llagostera, Esther ^a   Soto Cerrato, Vanessa ^a   Montaner, Beatriz ^a   Pérez Tomás, Ricardo ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

AIF; Apoptosis; Cytochrome c; Mitochondria; Prodigiosin

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE; CYTOCHROME C; HOE 33342; PRODIGIOSIN;

APOPTOSIS; CONFERENCE PAPER; CONTROLLED STUDY; CYTOSOL; DRUG MECHANISM; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; MITOCHONDRION; REACTION TIME;

SERRATIA MARCESCENS;

EID: 1342347880     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1299.030     Document Type: Conference Paper

References (5)

1. MONTANER, B., S. NAVARRO, M. PIQUÉ, et al. 2000. Prodigiosin from the supernatant of Serratia marcescens induces apoptosis in haematopoietic cancer cell lines. Br. J. Pharmacol. 131: 585-593.
2. MONTANER, B. & R. PÉREZ-TOMÁS. 2001. Prodigiosin-induced apoptosis in human colon cancer cells. Life Sci. 68: 2025-2036.
3. CAMPAS, C., M. DALMAU, B. MONTANER, et al. 2003. Prodigiosin induces apoptosis of B and T cells from B-cell chronic lymphocytic leukemia. Leukemia 17: in press.
4. LORENZO, H.K., S.A. SUSIN, J. PENNINGER & G. KROEMER. 1999. Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death. Cell Death Differ. 6: 516-524.
5. MONTANER, B. & R. PÉREZ-TOMÁS. 2002. Prodigiosin induces caspase-9 and caspase-8 activation and cytochrome c release in Jurkat T cells. Ann. N.Y. Acad. Sci. 973: 246-249.