MPP+-induced degeneration is potentiated by dicoumarol in cultures of the RCSN-3 dopaminergic cell line. Implications of neuromelanin in oxidative metabolism of dopamine neurotoxicity

Neurotoxicity Research

Volumn 5, Issue 6, 2003, Pages 407-410

  Aguilar Hernandez R ^a   Sanchez de las Matas M J ^a   Arriagada, C ^b   Barcia, C ^a   Caviedes, P ^b   Herrero, M T ^a   Segura Aguilar, J ^b  

^a UNIVERSITY OF MURCIA   (Spain)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

Calpain; Dicoumarol; DNA Fragmentation; Dopamine; DT Diaphorase; MPTP; Neurotoxicity

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CALPAIN; DICOUMAROL; DNA FRAGMENT; DOPAMINE; DOPAMINE RECEPTOR STIMULATING AGENT; ENZYME INHIBITOR; MELANIN; NEUROMELANIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANIMAL; ARTICLE; CELL DEATH; CELL LINE; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; NERVE DEGENERATION; OXIDATION REDUCTION REACTION; PATHOLOGY; PHYSIOLOGY; RAT;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; 1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; CALPAIN; CELL DEATH; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DICUMAROL; DNA FRAGMENTATION; DOPAMINE; DOPAMINE AGENTS; ENZYME ACTIVATION; ENZYME INHIBITORS; MELANINS; NAD(P)H DEHYDROGENASE (QUINONE); NERVE DEGENERATION; OXIDATION-REDUCTION; RATS;

EID: 1342333625     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03033169     Document Type: Article

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