CD86 Blockade in Genetically Modified Porcine Cells Delays Xenograft Rejection by Inhibiting T-Cell and NK-Cell Activation

Cell Transplantation

Volumn 13, Issue 1, 2004, Pages 75-87

  Costa, Cristina ^a   Pizzolato, Maryellen C ^a   Shen, Yamin ^a   Wang, Yi ^a   Fodor, William L ^a,b  

^a ALEXION PHARMACEUTICALS   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Antibody response; CD152 antigen; CD86 antigen; NK cells; T cells; Xenotransplantation

Indexed keywords

ANTIGEN; CD59 ANTIGEN; CD86 ANTIGEN; CONCANAVALIN A; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA MODIFICATION; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; SWINE; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; XENOGRAFT;

ANIMALIA; MURINAE; PRIMATES; SUIDAE; SUS SCROFA;

EID: 1342331051     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/000000004772664923     Document Type: Article

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