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Volumn 69, Issue 6, 2000, Pages 1176-1185

Pancreatic islet xenograft tolerance after short-term costimulation blockade is associated with increased CD4+ T cell apoptosis but not immune deviation

Author keywords

[No Author keywords available]

Indexed keywords

ANNEXIN; CD4 ANTIGEN;

EID: 0034719664     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200003270-00024     Document Type: Article
Times cited : (59)

References (48)
  • 1
    • 0024506159 scopus 로고
    • Regulation of lymphokine messenger RNA stability by a surface-mediated T-cell activation pathway
    • Lindsten T, June CH, Ledbetter JA, Stella G, Thompson CB. Regulation of lymphokine messenger RNA stability by a surface-mediated T-cell activation pathway. Science 1989; 244: 339.
    • (1989) Science , vol.244 , pp. 339
    • Lindsten, T.1    June, Ch.2    Ledbetter, J.A.3    Stella, G.4    Thompson, C.B.5
  • 2
    • 0027087331 scopus 로고
    • Costimulation of T lymphocytes: The role of CD28, CTLA4 and B7/BB1 in interleukin-2 production and immunotherapy
    • Schwartz RH. Costimulation of T lymphocytes: the role of CD28, CTLA4 and B7/BB1 in interleukin-2 production and immunotherapy. Cell 1992; 71: 1065.
    • (1992) Cell , vol.71 , pp. 1065
    • Schwartz, R.H.1
  • 3
    • 0026552387 scopus 로고
    • Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells
    • Razi-wolf Z, Freeman GJ, Galvin R, Benacerraf B, Nadler L, Reiser H. Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells. Proc Natl Acad Sci USA 1992; 89: 4210.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4210
    • Razi-Wolf, Z.1    Freeman, G.J.2    Galvin, R.3    Benacerraf, B.4    Nadler, L.5    Reiser, H.6
  • 4
    • 0027397169 scopus 로고
    • Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1
    • Tan P, Anasetti C, Hansen JA, et al. Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1. J Exp Med 1993; 177: 165.
    • (1993) J Exp Med , vol.177 , pp. 165
    • Tan, P.1    Anasetti, C.2    Hansen, J.A.3
  • 5
    • 0028500255 scopus 로고
    • Absence of B7-dependent responses in CD28-deficient mice
    • Green JM, Noel PJ, Sperling AI, et al. Absence of B7-dependent responses in CD28-deficient mice. Immunity 1994; 1: 501.
    • (1994) Immunity , vol.1 , pp. 501
    • Green, J.M.1    Noel, P.J.2    Sperling, A.I.3
  • 9
    • 0030028044 scopus 로고    scopus 로고
    • Impaired T cell-mediated macrophage activation in CD40 ligand-deficient mice
    • Stout RD, Suttles J, Xu J, Grewal S, Flavell RA. Impaired T cell-mediated macrophage activation in CD40 ligand-deficient mice. J Immunol 1996; 156: 8.
    • (1996) J Immunol , vol.156 , pp. 8
    • Stout, R.D.1    Suttles, J.2    Xu, J.3    Grewal, S.4    Flavell, R.A.5
  • 10
    • 0029890580 scopus 로고    scopus 로고
    • CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CDS+ CTL response
    • Borrow P, Tishon A, Lee S, et al. CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CDS+ CTL response. J Exp Med 1996; 183: 2129.
    • (1996) J Exp Med , vol.183 , pp. 2129
    • Borrow, P.1    Tishon, A.2    Lee, S.3
  • 12
    • 0026459468 scopus 로고
    • T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo
    • Turka LA, Linsley PS, Lin H, et al. T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo. Proc Natl Acad Sci USA 1992; 89: 11102.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11102
    • Turka, L.A.1    Linsley, P.S.2    Lin, H.3
  • 13
    • 0026738641 scopus 로고
    • Long term survival of xenogeneic pancreatic islet grafts induced by CTLA4-Ig
    • Lenschow DJ, Zeng Y, Thistlewaite R, et al. Long term survival of xenogeneic pancreatic islet grafts induced by CTLA4-Ig. Science 1992; 257: 789.
    • (1992) Science , vol.257 , pp. 789
    • Lenschow, D.J.1    Zeng, Y.2    Thistlewaite, R.3
  • 15
    • 0028903939 scopus 로고
    • CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2
    • Sayegh MH, Aklin E, Hancock WW, et al. CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2. J Exp Med 1995; 181: 1869.
    • (1995) J Exp Med , vol.181 , pp. 1869
    • Sayegh, M.H.1    Aklin, E.2    Hancock, W.W.3
  • 16
    • 0031230372 scopus 로고    scopus 로고
    • Distinct mechanisms for the induction and maintenance of allograft tolerance with CTLA4-Fc treatment
    • Tran HM, Nickerson PW, Restifo AC, et al. Distinct mechanisms for the induction and maintenance of allograft tolerance with CTLA4-Fc treatment. J Immunol 1997; 159: 2232.
    • (1997) J Immunol , vol.159 , pp. 2232
    • Tran, H.M.1    Nickerson, P.W.2    Restifo, A.C.3
  • 18
    • 15844404353 scopus 로고    scopus 로고
    • Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways
    • Larsen CP, Elwood ET, Alexander DZ, et al. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature 1996; 381: 434.
    • (1996) Nature , vol.381 , pp. 434
    • Larsen, C.P.1    Elwood, E.T.2    Alexander, D.Z.3
  • 20
    • 12644262358 scopus 로고    scopus 로고
    • CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
    • Kirk AD, Harlan DM, Armstrong NN, et al. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc Natl Acad Sci USA 1997; 94: 8789.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8789
    • Kirk, A.D.1    Harlan, D.M.2    Armstrong, N.N.3
  • 21
    • 0004880266 scopus 로고    scopus 로고
    • CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal anti-body treatment
    • Zheng XX, Markees TG, Hancock WW, et al. CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal anti-body treatment. J Immunol 1999; 162: 4983.
    • (1999) J Immunol , vol.162 , pp. 4983
    • Zheng, X.X.1    Markees, T.G.2    Hancock, W.W.3
  • 22
    • 0345164351 scopus 로고    scopus 로고
    • Combined costimulation blockade plus rapamycin but not cyclosporine produces permanent engraftment
    • Li Y, Zheng XX, Li CX, Zand MS, Strom TB. Combined costimulation blockade plus rapamycin but not cyclosporine produces permanent engraftment. Transplantation 1998; 66: 1387.
    • (1998) Transplantation , vol.66 , pp. 1387
    • Li, Y.1    Zheng, X.X.2    Li, C.X.3    Zand, M.S.4    Strom, T.B.5
  • 23
    • 0027499535 scopus 로고
    • Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal
    • Ranheim EA, Kipps TJ. Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal. J Exp Med 1993; 177: 925.
    • (1993) J Exp Med , vol.177 , pp. 925
    • Ranheim, E.A.1    Kipps, T.J.2
  • 24
    • 0030474264 scopus 로고    scopus 로고
    • Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection
    • Hancock WW, Sayegh MH, Zheng XG, Peach R, Linsley PS, Turka LA. Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection. Proc Natl Acad Sci USA 1996; 93: 13967.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13967
    • Hancock, W.W.1    Sayegh, M.H.2    Zheng, X.G.3    Peach, R.4    Linsley, P.S.5    Turka, L.A.6
  • 25
    • 0031945499 scopus 로고    scopus 로고
    • How do monoclonal antibodies induce tolerance?
    • Waldman H, Cobbold S. How do monoclonal antibodies induce tolerance? Annu Rev Immunol 1998; 16: 619.
    • (1998) Annu Rev Immunol , vol.16 , pp. 619
    • Waldman, H.1    Cobbold, S.2
  • 26
    • 0028027043 scopus 로고
    • Mechanisms in CD4 antibody-mediated transplantation tolerance: Kinetics of induction, antigen dependency and role of regulatory T-cells
    • Scully R, Qin S, Cobbold SP, Waldmann H. Mechanisms in CD4 antibody-mediated transplantation tolerance: kinetics of induction, antigen dependency and role of regulatory T-cells. Eur J Immunol 1994; 24: 2383.
    • (1994) Eur J Immunol , vol.24 , pp. 2383
    • Scully, R.1    Qin, S.2    Cobbold, S.P.3    Waldmann, H.4
  • 27
    • 0026772133 scopus 로고
    • A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells
    • Noelle RJ, Roy M, Shepherd DM, Stamenkovic I, Ledbetter JA, Aruffo A. A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. Proc Natl Acad Sci USA 1992; 89: 6550.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6550
    • Noelle, R.J.1    Roy, M.2    Shepherd, D.M.3    Stamenkovic, I.4    Ledbetter, J.A.5    Aruffo, A.6
  • 28
    • 0030699374 scopus 로고    scopus 로고
    • The cytokine and histological response in islet xenograft rejection is dependent upon species combination
    • Medbury HJ, Hibbins M, Lehnert AM, et al. The cytokine and histological response in islet xenograft rejection is dependent upon species combination. Transplantation 1997; A64: 1307.
    • (1997) Transplantation , vol.64 A , pp. 1307
    • Medbury, H.J.1    Hibbins, M.2    Lehnert, A.M.3
  • 29
    • 0033057386 scopus 로고    scopus 로고
    • Intrathymic inoculation of donor antigen: And ineffective strategy for prolonging xenograft survival
    • Tran HM, Patel A, Allen RDM, O'Connell PJ. Intrathymic inoculation of donor antigen: and ineffective strategy for prolonging xenograft survival. Xenotransplantation 1999; 6: 1.
    • (1999) Xenotransplantation , vol.6 , pp. 1
    • Tran, H.M.1    Patel, A.2    Allen, R.D.M.3    O'Connell, P.J.4
  • 30
    • 0028042309 scopus 로고
    • Induction of tolerance of islet xenografts in a concordant rat-to-mouse model
    • Goss JA, Nakafusa Y, Finke EH, Flye MW, Lacy PE. Induction of tolerance of islet xenografts in a concordant rat-to-mouse model. Diabetes 1994; 43: 16.
    • (1994) Diabetes , vol.43 , pp. 16
    • Goss, J.A.1    Nakafusa, Y.2    Finke, E.H.3    Flye, M.W.4    Lacy, P.E.5
  • 31
    • 0032526076 scopus 로고    scopus 로고
    • Prolonged acceptance of concordant and discordant xenografts with combined CD40 and CD28 pathway blockade
    • Elwood ET, Larsen CP, Cho HR, et al. Prolonged acceptance of concordant and discordant xenografts with combined CD40 and CD28 pathway blockade. Transplantation 1998; 65: 1422.
    • (1998) Transplantation , vol.65 , pp. 1422
    • Elwood, E.T.1    Larsen, C.P.2    Cho, H.R.3
  • 32
    • 0031818893 scopus 로고    scopus 로고
    • Prolonged survival of rat islet and skin xenografts in mice treated with donor spleno-cytes and anti-CD154 monoclonal antibody
    • Gordon EJ, Markees TG, Phillips NE, et al. Prolonged survival of rat islet and skin xenografts in mice treated with donor spleno-cytes and anti-CD154 monoclonal antibody. Diabetes 1998; 47 (8): 1199.
    • (1998) Diabetes , vol.47 , Issue.8 , pp. 1199
    • Gordon, E.J.1    Markees, T.G.2    Phillips, N.E.3
  • 35
    • 0026729563 scopus 로고
    • Heart allografts in murine systems: The differential activation of Th2-like effector cells in peripheral tolerance
    • Takeuchi T, Lowry RP, Konieczny B. Heart allografts in murine systems: the differential activation of Th2-like effector cells in peripheral tolerance. Transplantation 1992; 53: 1281.
    • (1992) Transplantation , vol.53 , pp. 1281
    • Takeuchi, T.1    Lowry, R.P.2    Konieczny, B.3
  • 36
    • 0031568550 scopus 로고    scopus 로고
    • Type 2 helper T-cell type cytokines and the development of "infectious" tolerance in rat cardiac allograft recipients
    • Onodera K, Hancock WW, Graser E, et al. Type 2 helper T-cell type cytokines and the development of "infectious" tolerance in rat cardiac allograft recipients. J Immunol 1997; 158: 1572.
    • (1997) J Immunol , vol.158 , pp. 1572
    • Onodera, K.1    Hancock, W.W.2    Graser, E.3
  • 37
    • 0000770628 scopus 로고    scopus 로고
    • On histocompatibility barriers, Th1 to Th2 immune deviation, and the nature of the allograft responses
    • Li XC, Zand MS, Li Y, Zheng XX, Strom TB. On histocompatibility barriers, Th1 to Th2 immune deviation, and the nature of the allograft responses. J Immunol 1998; 161: 2241.
    • (1998) J Immunol , vol.161 , pp. 2241
    • Li, X.C.1    Zand, M.S.2    Li, Y.3    Zheng, X.X.4    Strom, T.B.5
  • 38
    • 0028909086 scopus 로고
    • Intragraft expression of cytokine transcripts during pig proislet xenograft rejection and tolerance in mice
    • Morris CF, Simeonovic CJ, Fung M-C, Wilson JD, Hapel AJ. Intragraft expression of cytokine transcripts during pig proislet xenograft rejection and tolerance in mice. J Immunol 1995; 154: 2470.
    • (1995) J Immunol , vol.154 , pp. 2470
    • Morris, C.F.1    Simeonovic, C.J.2    Fung, M.-C.3    Wilson, J.D.4    Hapel, A.J.5
  • 39
    • 0028915454 scopus 로고
    • Regulation of lymphocyte survival by the Bcl-2 gene family
    • Cory S. Regulation of lymphocyte survival by the Bcl-2 gene family. Annu Rev Immunol 1995; 13: 513.
    • (1995) Annu Rev Immunol , vol.13 , pp. 513
    • Cory, S.1
  • 40
    • 0028983657 scopus 로고
    • Cell-autonomous Fas (CD95)/Fas-ligand interaction mediated activation-induced apoptosis in T-cell hybridomas
    • Brunner T, Mogil RJ, LaFace D, et al. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediated activation-induced apoptosis in T-cell hybridomas. Nature 1995; 373: 441.
    • (1995) Nature , vol.373 , pp. 441
    • Brunner, T.1    Mogil, R.J.2    LaFace, D.3
  • 41
    • 0028893078 scopus 로고
    • Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation
    • Ju ST, Panka D, Cui H, et al. Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995; 373: 444.
    • (1995) Nature , vol.373 , pp. 444
    • Ju, S.T.1    Panka, D.2    Cui, H.3
  • 42
    • 0031569514 scopus 로고    scopus 로고
    • Functional responses and apoptosis in CD25 (IL-2Ra)-deficient lymphocytes expressing a transgenic antigen receptor
    • Van Parijs L, Biuckians A, Ibraghimov A, Alt FW, Willerford D, Abbas A. Functional responses and apoptosis in CD25 (IL-2Ra)-deficient lymphocytes expressing a transgenic antigen receptor. J Immunol 1997; 158: 3738.
    • (1997) J Immunol , vol.158 , pp. 3738
    • Van Parijs, L.1    Biuckians, A.2    Ibraghimov, A.3    Alt, F.W.4    Willerford, D.5    Abbas, A.6
  • 43
    • 0029118133 scopus 로고
    • Normal clonal expansion but impaired Fas-mediated cell death and anergy in IL-2 deficient mice
    • Kneitz B, Herrmann T, Yonehara S, Schimpl A. Normal clonal expansion but impaired Fas-mediated cell death and anergy in IL-2 deficient mice. Eur J Immunol 1995; 25: 2572.
    • (1995) Eur J Immunol , vol.25 , pp. 2572
    • Kneitz, B.1    Herrmann, T.2    Yonehara, S.3    Schimpl, A.4
  • 44
    • 0013195631 scopus 로고    scopus 로고
    • IL-2 and IL-4 double knockout mice reject islet allografts: A role for novel T-cell growth factors in Allograft rejection
    • Li XC, Roy-Chaudhury P, Hancock WW, et al. IL-2 and IL-4 double knockout mice reject islet allografts: A role for novel T-cell growth factors in Allograft rejection. J Immunol 1998; 161: 890.
    • (1998) J Immunol , vol.161 , pp. 890
    • Li, X.C.1    Roy-Chaudhury, P.2    Hancock, W.W.3
  • 45
    • 0032529195 scopus 로고    scopus 로고
    • Impaired alloantigen-mediated T cell apoptosis and failure to induce long-term allograft survival in IL-2-deficient mice
    • Dai Z, Konieczny BT, Baddoura FK, Lakkis FG. Impaired alloantigen-mediated T cell apoptosis and failure to induce long-term allograft survival in IL-2-deficient mice. J Immunol 1998; 161: 1659.
    • (1998) J Immunol , vol.161 , pp. 1659
    • Dai, Z.1    Konieczny, B.T.2    Baddoura, F.K.3    Lakkis, F.G.4
  • 46
    • 0344613988 scopus 로고    scopus 로고
    • Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance
    • Li Y, Li XC, Zheng XX, Wells AD, Turka LA, Strom TB. Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance. Natl Med 1999; 5(11): 1298.
    • (1999) Natl Med , vol.5 , Issue.11 , pp. 1298
    • Li, Y.1    Li, X.C.2    Zheng, X.X.3    Wells, A.D.4    Turka, L.A.5    Strom, T.B.6
  • 47
    • 0032996025 scopus 로고    scopus 로고
    • Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
    • Kirk AD, Burkly LC, Batty DS, et al. Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates. Nature Med 1999; 5: 686.
    • (1999) Nature Med , vol.5 , pp. 686
    • Kirk, A.D.1    Burkly, L.C.2    Batty, D.S.3
  • 48
    • 0345476290 scopus 로고    scopus 로고
    • Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance
    • Wells AD, Li XC, Li Y, et al. Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. Natl Med 1999; 5 (11): 1303.
    • (1999) Natl Med , vol.5 , Issue.11 , pp. 1303
    • Wells, A.D.1    Li, X.C.2    Li, Y.3


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