Inhibition of Liver Cancer Cell Proliferation and Migration by a Combination of (-)-Epigallocatechin-3-Gallate and Ascorbic Acid

Journal of Chemotherapy

Volumn 15, Issue 6, 2003, Pages 591-595

  Wei, D Z ^a   Yang, J Y ^a   Liu, J W ^a   Tong, W Y ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Ascorbic acid (AA); Cancer; Epigallocatechin gallate (EGCG); Metastasis; Proliferation; Reactive oxygen species (ROS)

Indexed keywords

AGAR; ASCORBIC ACID; EPIGALLOCATECHIN GALLATE;

ANTIOXIDANT ACTIVITY; ARTICLE; CANCER INHIBITION; CELL LINE; CELL MIGRATION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FLUOROGRAPHY; HUMAN; HUMAN CELL; LIVER CANCER; METASTASIS; OXIDATIVE STRESS;

EID: 1342326779     PISSN: 1120009X     EISSN: None     Source Type: Journal    
DOI: 10.1179/joc.2003.15.6.591     Document Type: Article

References (27)

1. Crawford D, Zbinden I, Amstad P, Cerutti P. Oxidant stress induces the proto-oncogenes c-fos and c-myc in mouse epidermal cells. Oncogene 1988; 3: 27-32.
2. Nonaka Y, Iwagaki H, Kimura T, Fuchimoto S, Orita K. Effect of reactive oxygen intermediates on the in vitro invasive capacity of tumor cells and liver metastasis in mice. Int J Cancer 1993; 54: 983-986.
3. Young DJ, Lee ME. Inhibition of tumour invasion and angiogenesis by epigallicatechin gallate (EGCG), a major component of green tea. Int J Exp Pathol 2001; 82: 309-316.
4. Chen ZY, Zhu QY, David T, Huang Y. Degradation of green tea catechins in tea drinks. J Agric Food Chem 2001; 49: 477-483.
5. Chen ZY, Zhu QY, Wong YF, Zhang ZS, Hauyin C. Stabilizing effect of ascorbic acid on green tea catechins. J Agric Food Chem 1998; 46: 2512-2516.
6. Zhao BL. Oxygen Free Radical and Nature Antioxidant. 1st ed. Beijing, China: Science Press. 1999: 205.
7. 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells. Cell 1990; 60: 849-859.
8. Sejda P, Parce JW, Seeds MS, Bass DA. Flow cytometric quantitation of oxidative produce formation by polymorphonu-clear leukocytes during phagocytosis. J Immunol 1984; 133: 3303-3307.
9. Miura Y, Shiomi H, Sakai F, Yagasaki K. Assay system for screening food components that have anti-proliferative and anti-invasion activity to rat ascites hepatoma cells: in vitro and ex vivo effects of green tea extract. Cytotechnology 1999; 31: 127-133.
10. Zhang GY, Miura Y, Yagasaki K. Effects of green, oolong and blank teas and related components on the proliferation and invasion of liver cancer cells in culture. Cytotechnology 1999; 31: 37-44.
11. Jean-Dean L, Sheng-Hsuan C, Chin-Li L, Shu-Huei T, Yu-Chih, L. Inhibition of melanoma growth and metastasis by combination with (-)-epigallocatechin-3-gallate and dacarbazine in mice. J Cell Biochem 2001; 83: 631-642.
12. Hidvegi M, Raso E, Tomoskozi-Farkas R, Paku S, Lapis k, Szende B. Effect of avemar and avemar + Vitamin C on tumor growth and metastasis in experimental animals. Anticancer Res 1998; 18: 2353-2358.
13. Miwa N, Yamazaki H. Potentiated susceptibility of ascites tumor to acyl derivatives of ascorbate caused by balanced hydrophobicity in the molecule. Exp Cell Biol 1986; 54: 245-50
14. Price JE. Clonogenicity and experimental metastatic potential of spontaneous mouse mammary neoplasms. J Natl Cancer Inst 1986; 77: 529-535.
15. Gohji K, Nakajima M, Boyd D, et al. Organ-site dependence for the production of urokinase-type plasminogen activator and metastasis by human renal cell carcinoma cells. Am J Pathol 1997; 151: 1655-1661.
16. Jankun J, Selman SH, Swiercz R, Skrzypczak-Jankun E. Why drinking green tea could prevent cancer. Nature 1997; 387: 561.
17. Garbisa S, Sartor L, Biggin S, Salvato B, Benelli R, Albini A. Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin-3-gallate. Cancer 2001; 91: 822-832.
18. Yasuo S, Mamoru I. Inhibitory effect of epigallocatechin gallate on adhesion of murine melanoma cells to laminin. Cancer Lett 2001; 173: 15-20.
19. Fidler IJ, Ellis LM. The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell 1994; 79: 185-188.
20. Jung YD, Kim MS, Shin BA, et al. EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells. Br J Cancer 2001, 84: 844-850.
21. Jian-wen L, Norio N, Katsuhiro K, Nobuhiko M. Antimetastatic and anti-invasion ability of phospho-ascorbyl palmitate through intracellular ascorbate enrichment and the resultant antioxidant action. Oncol Res 1999; 11: 479-487.
22. Szatrowski TP, Nathan CF. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res 1991; 51: 794-798.
23. Nonaka Y, Iwagaki H, Kimura T, Fuchimoto S, Orita K. Effect of reactive oxygen intermediates on the in vitro invasive capacity of tumor cells and liver metastasis in mice. J Cancer 1993; 54: 983-986.
24. Brenneisen P, Briviba K, Wlaschek M, Wenk J, Scharffetter KK. Hydrogen peroxide (H2O2) increases the steady-state mRNA levels of collagenase / MMP -1 in human dermal fibroblasts. Free Radic Biol Med 1997; 22: 515-524.
25. Kozuki Y, Miura Y, Yagasaki K. Inhibitory effects of carotenoids on the invasion of rat ascites liver cancer cells in culture. Cancer Lett 2000; 151: 111-115.
26. Norio N, Tetsuya E, Shoji Y, Takashi O, Nobuhiko M. Enhanced invasion of tax-expressing fibroblasts into the basement membrane is repressed by phosphorylated ascorbate with simultaneous decreases in intracellular oxidative stress and NF-κB activation. Antioxidants Redox Signaling 2000; 2: 727-738.
27. Hara M, Okushio K. Stability of catechins in aqueous solutions. Jpn Kokai Tokkyo Koho 1989; JP 01233277A2890919.