Perfusion-weighted MRI as a marker of response to treatment in acute and subacute stroke

Neuroradiology

Volumn 46, Issue 1, 2004, Pages 31-39

  Hillis, Argye E ^a,b   Wityk, R J ^a   Beauchamp, N J ^a   Ulatowski, J A ^a   Jacobs, M A ^a   Barker, P B ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Magnetic resonance imaging; Perfusion weighted imaging; Stroke treatment

Indexed keywords

ACETYLSALICYLIC ACID; ANTIHYPERTENSIVE AGENT; FLUDROCORTISONE; GADOLINIUM PENTETATE; INFUSION FLUID; MIDODRINE; PHENYLEPHRINE; SODIUM CHLORIDE;

ACUTE DISEASE; ADULT; AGE; AGED; ARTICLE; BRAIN BLOOD VOLUME; BRAIN INFARCTION SIZE; BRAIN PERFUSION; BRAIN REGION; BRAIN TISSUE; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; FISHER EXACT TEST; FOLLOW UP; FUNCTIONAL ASSESSMENT; HEALTH CARE ORGANIZATION; HUMAN; HUMAN TISSUE; HYPERTENSION; IMAGING SYSTEM; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RATING SCALE; REPERFUSION; STATISTICAL SIGNIFICANCE; SYMPTOMATOLOGY; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; BRAIN; BRAIN ISCHEMIA; CARDIOTONIC AGENTS; CEREBROVASCULAR ACCIDENT; COGNITION DISORDERS; ENDPOINT DETERMINATION; FEMALE; FLUID THERAPY; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MIDDLE AGED; PHENYLEPHRINE; PROGNOSIS; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 1342325732     PISSN: 00283940     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00234-002-0918-4     Document Type: Article

References (38)

1. Lutsep HL, Albers GW, DeCrespigny A, Kamat GN, Marks MP, Moseley ME (1997) Clinical utility of diffusion-weighted magnetic imaging in the assessment of ischemic stroke. Ann Neurol 41: 574-580
2. Beauchamp N, Bryan RN (1998) Acute cerebral ischemic infarction: a pathophysiologic review and radiologic perspective. Am J Roentgenol 171: 73-84
3. Fisher M, Albers GW (1999) Applications of diffusion-perfusion magnetic resonance imaging in acute ischemic stroke. Neurol 52: 1750-1756
4. Sorensen AG, Buonanno FS, Gonzalez RG, et al (1996) Hyperacute stroke: evaluation with combined multisection diffusion-weighted imaging and hemodynamically-weighted echo-planar MR imaging. Radiology 199: 391-401
5. Skyhøj Olsen T, Bruhn P, Oberg RG (1986) Cortical hypoperfusion as a possible cause of "subcortical aphasia". Brain 106: 393-410
6. Powers, WJ (1993) Acute hypertension after stroke: the scientific basis for treatment decisions. Neurology 43: 461-467
7. Baron JC, Marchal G (2000) Functional imaging in vascular disorders. In: Mazziotta JC, Toga AW, Frackowiak RSJ (eds) Brain mapping: the disorders. Academic Press, San Diego, pp 299-311
8. Hakim AM (1998) Ischemic penumbra: the therapeutic window. Neurology 51: S44-S46
9. Schellinger PD, Fiebach JB, Jansen O, et al (2001) Stroke magnetic resonance imaging within 6 hours after onset of hyperacute cerebral ischemia. Ann Neurol 49: 460-469
10. Sunshine, JL, Tarr RW, Lanzieri CF, Landis DMD, Selman WR, Lewin JS (1999) Hyperacute stroke: ultrafast MR imaging to triage patients prior to therapy. Radiology 212: 325-332
11. Schlaug G, Benfield A, Baird AS, et al (1999) The ischemic penumbra operationally defined by diffusion and perfusion MRI. Neurology 53: 1528-1537
12. Barber PA, Darby DG, Desmond PM, et al (1998) Prediction of stroke outcome with echoplanar perfusion- and diffusion-weighted MRI. Neurology 51: 418-426
13. Hillis AE, Barker PB, Beauchamp NJ, Gordon, B, Wityk RJ (2000) MR perfusion imaging reveals regions of hypoperfusion associated with aphasia and neglect. Neurology 55: 782-788
14. Jacobs MA, Simpson C, Giugni E, et al (in press) MR perfusion imaging in acute stroke: comparison of time to peak and mean transit time. Stroke 33: 367 [abstract]
15. Parsons MW, Yang, Q, Barber PA, et al (2000) MR perfusion imaging: acute rCBF is more accurate than rMTT or rCBV in prediction of infarct size. Stroke 31: 275
16. Wityk RJ, Hillis AE, Beauchamp N, Aldrich E, Barker P (2000) Mismatch of diffusion-perfusion weighted MRI in stroke patients beyond 48 hours. Neurology 54 [Suppl 3]: A474 [abstract]
17. Hillis AE, Barker PB, Beauchamp NJ, Winters BD, Mirski M, Wityk RJ (2001) Restoring blood pressure reperfused Wernicke's area and improved language. Neurology 56: 670-672
18. Alberts MJ (1999) tPA in acute ischemic stroke. Neurology 51 [Suppl 3]: S53-S55
19. Wise G, Sutter R, Burkholder J (1972) The treatment of brain ischemia with vasopressor drugs. Stroke 3: 135-140
20. Rordorf G, Cramer SC, Efird JT, Schwamm LH, Buonanno F, Koroshetz W (1997) Pharmacological elevation of blood pressure in acute stroke. Stroke 28: 2133-2138
21. Rordorf G, Koroshetz W., Ezzeddine MA, Segal AZ, Buonanno FS (2001) A pilot study of drug-induced hypertension for treatment of acute stroke. Neurology 56: 1210-1213
22. Astrup J, Symon L, Branston NM, Lassen NA (1977) Cortical evoked potential and extracellular K + and H + at critical levels of brain ischemia. Stroke 8: 51-57
23. Skyhøj Olsen T, Larsen B, Herning M, Skriver EB, Lassen N (1983) Blood flow and vascular reactivity in collaterally perfused brain tissue. Stroke 14: 332-401
24. Wityk RJ, Pessin MS, Kaplan RF, Caplan LR (1994) Serial assessment of acute stroke using the NIH stroke scale. Stroke 25: 362-365
25. Hillis AE, Kane A, Tuffiash E, et al (in press) Reperfusion of specific brain regions by raising blood pressure restores selective language functions in subacute stroke. Brain Lang 79: 495-510
26. Heiss WD (1983) Flow thresholds for functional and morphological damage of brain tissue. Stroke 14: 329-331
27. Nakano S, Kinoshita K, Jinnouchi S, Hoshi H, Watanabe K (1989) Critical cerebral blood flow thresholds studied by SPECT using xenon-133 iodoamphetamine. J Nucl Med 30: 337-342
28. Buell U, Braun H, Ferert A, Stirner H, Weiller C, Ringlestein EB (1988) Combined SPECT imaging of regional cerebral blood flow (99mTc-hexemthyl-propyleneamine oxime, HMPAO) and blood volume (99mTc-RBC) to assess regional cerebral perfusion reserve in patients with cerebrovascular disease. Nuklearmedizin 27: 51-56
29. Lassen NA, Andersen AR (1988) Technetium-99 compounds for measurement of cerebral blood flow. J Nucl Med 29: 1464-1465
30. Hossmann KA (1994) Viability thresholds and the penumbra of focal ischemia. Ann Neurol 36: 557-565
31. Marks MP, Tong DC, Beaulieu C, Albers GW, de Crespigny A, Moseley ME (1999) Evaluation of early reperfusion and IV tPA therapy using diffusion- and perfusion-weighted MRI. Neurology 52: 1792-1798
32. Rordorf G, Koroshetz WJ, Copen WA, et al (1998) Regional ischemia and ischemic injury in patients with acute middle cerebral artery stroke as defined by early diffusion-weighted and perfusion-weighted MRI. Stroke 29: 939-943
33. Ackerman RH, Correia JA, Alpert NM, et al (1981) Positron imaging in ischemic stroke disease using compounds labeled with oxygen-15. Arch Neurol 38: 537-543
34. 15O positron tomography. Stroke 12: 454-459
35. Wise RJS, Bernardi S, Frackowiak RSJ, Legg NJ, Jones T (1983) Serial Observations on the pathophysiology of acute stroke. The transition from ischaemia to infarction as reflected in regional oxygen extraction. Brain 106: 197-222
36. Marchal G, Serrati C, Rioux P, et al (1993) PET imaging of cerebral perfusion and oxygen consumption in acute ischemic stroke: Relation to outcome. Lancet 341: 925-927
37. Marchal G, Rioux P, Serrati C, et al (1995) Value of acute-stage PET in predicting neurological outcome after ischemic stroke: Further assessment. Stroke 26: 524-525
38. Derdeyn CP, Yundt KD, Videen TO, Carpenter DA, Grubb RL, Powers WJ (1998) Increased oxygen extraction fraction is associated with prior ischemic events in patients with carotid occlusion. Stroke 29: 754-758