메뉴 건너뛰기




Volumn 308, Issue 3, 2004, Pages 1102-1110

Acute Cardiovascular Effects of Sibutramine in Conscious Rats

Author keywords

[No Author keywords available]

Indexed keywords

1 [1 (4 CHLOROPHENYL)CYCLOBUTYL] 3 METHYL 1 METHYLAMINOBUTANE; 1 AMINO 1 [1 (4 CHLOROPHENYL)CYCLOBUTYL] 3 METHYLBUTANE; ALPHA ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; NORADRENALIN; NORADRENALIN TRANSPORTER; NORADRENALIN UPTAKE INHIBITOR; PHENTOLAMINE; PROPRANOLOL; SEROTONIN UPTAKE INHIBITOR; SIBUTRAMINE;

EID: 1342323321     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.061259     Document Type: Article
Times cited : (16)

References (35)
  • 2
    • 0015506533 scopus 로고
    • Propranolol inhibition of renin secretion. A specific approach to diagnosis and treatment of renin-dependent hypertensive diseases
    • Buhler FR, Laragh JH, Baer L, Vaughan ED Jr., and Brunner HR (1972) Propranolol inhibition of renin secretion. A specific approach to diagnosis and treatment of renin-dependent hypertensive diseases. New Engl J Med 287:1209-1214.
    • (1972) New Engl J Med , vol.287 , pp. 1209-1214
    • Buhler, F.R.1    Laragh, J.H.2    Baer, L.3    Vaughan Jr., E.D.4    Brunner, H.R.5
  • 4
    • 0035064737 scopus 로고    scopus 로고
    • Anti-obesity drugs: A critical review of current therapies and future opportunities
    • Clapham JC, Arch JRS, and Tadayyon M (2001) Anti-obesity drugs: a critical review of current therapies and future opportunities. Pharmacol Ther 89:81-121.
    • (2001) Pharmacol Ther , vol.89 , pp. 81-121
    • Clapham, J.C.1    Arch, J.R.S.2    Tadayyon, M.3
  • 6
    • 0028875361 scopus 로고
    • G-nitro-L-arginine methyl ester: Methodological considerations for studies of small arteries
    • G-nitro-L-arginine methyl ester: methodological considerations for studies of small arteries. J Hypertens 13:1217-1221.
    • (1995) J Hypertens , vol.13 , pp. 1217-1221
    • Dunn, W.R.1    Gardiner, S.M.2
  • 7
    • 0031906177 scopus 로고    scopus 로고
    • Remodelling and enhanced myogenic tone in cerebral resistance arteries isolated from genetically hypertensive Brattleboro rats
    • Dunn WR, Wallis SJ, and Gardiner SM (1998) Remodelling and enhanced myogenic tone in cerebral resistance arteries isolated from genetically hypertensive Brattleboro rats. J Vasc Res 35:18-26.
    • (1998) J Vasc Res , vol.35 , pp. 18-26
    • Dunn, W.R.1    Wallis, S.J.2    Gardiner, S.M.3
  • 8
    • 0000197205 scopus 로고
    • Effects of metabolite 1 and 2 of sibutramine on the short-term control of food intake in the rat
    • Fantino M and Souquet AM (1995) Effects of metabolite 1 and 2 of sibutramine on the short-term control of food intake in the rat. Int J Obes 19:145.
    • (1995) Int J Obes , vol.19 , pp. 145
    • Fantino, M.1    Souquet, A.M.2
  • 9
    • 0034522392 scopus 로고    scopus 로고
    • Weight loss with sibutramine improves glycaemic control and other metabolic parameters in obese patients with type 2 diabetes mellitus
    • Fujioka K, Seaton TB, and Rowe E (2000) Weight loss with sibutramine improves glycaemic control and other metabolic parameters in obese patients with type 2 diabetes mellitus. Diab Obes Metab 2:175-187.
    • (2000) Diab Obes Metab , vol.2 , pp. 175-187
    • Fujioka, K.1    Seaton, T.B.2    Rowe, E.3
  • 10
    • 0023786342 scopus 로고
    • Regional hemodynamic responses to adrenoceptor antagonism in conscious rats
    • Gardiner SM and Bennett T (1988) Regional hemodynamic responses to adrenoceptor antagonism in conscious rats. Am J Physiol 255:H813-H824.
    • (1988) Am J Physiol , vol.255
    • Gardiner, S.M.1    Bennett, T.2
  • 12
    • 0025922250 scopus 로고
    • G-nitro-L-arginine methyl ester on vasodilator responses to acetylcholine, 5′-N-ethylcarboxamidoadenosine or salbutamol in conscious rats
    • G-nitro-L-arginine methyl ester on vasodilator responses to acetylcholine, 5′-N-ethylcarboxamidoadenosine or salbutamol in conscious rats. Br J Pharmacol 103:1725-1732.
    • (1991) Br J Pharmacol , vol.103 , pp. 1725-1732
    • Gardiner, S.M.1    Kemp, P.A.2    Bennett, T.3
  • 13
    • 0027184742 scopus 로고
    • Regional haemodynamic effects of angiotensin II (3-8) in conscious rats
    • Gardiner SM, Kemp PA, March JE, and Bennett T (1993) Regional haemodynamic effects of angiotensin II (3-8) in conscious rats. Br J Pharmacol 110:159-162.
    • (1993) Br J Pharmacol , vol.110 , pp. 159-162
    • Gardiner, S.M.1    Kemp, P.A.2    March, J.E.3    Bennett, T.4
  • 14
    • 0036246870 scopus 로고    scopus 로고
    • Complex regional haemodynamic effects of anandamide in conscious rats
    • Gardiner SM, March JE, Kemp PA, and Bennett T (2002) Complex regional haemodynamic effects of anandamide in conscious rats. Br J Pharmacol 135:1889-1896.
    • (2002) Br J Pharmacol , vol.135 , pp. 1889-1896
    • Gardiner, S.M.1    March, J.E.2    Kemp, P.A.3    Bennett, T.4
  • 16
    • 0034999544 scopus 로고    scopus 로고
    • Vascular adrenoceptors: An update
    • Guimaraes S and Moura D (2001) Vascular adrenoceptors: an update. Pharmacol Rev 53:319-356.
    • (2001) Pharmacol Rev , vol.53 , pp. 319-356
    • Guimaraes, S.1    Moura, D.2
  • 17
    • 0032189856 scopus 로고    scopus 로고
    • Behavioural satiety sequence (BSS) for the diagnosis of drug action on food intake
    • Halford JCG, Wanninayake SCD, and Blundell JE (1998) Behavioural satiety sequence (BSS) for the diagnosis of drug action on food intake. Pharmacol Biochem Behav 61:159-168.
    • (1998) Pharmacol Biochem Behav , vol.61 , pp. 159-168
    • Halford, J.C.G.1    Wanninayake, S.C.D.2    Blundell, J.E.3
  • 18
    • 0021706072 scopus 로고
    • Mechanical behavior of pressurized in vitro prearteriolar vessels determined with a video system
    • Halpern W, Osol G, and Coy GS (1984) Mechanical behavior of pressurized in vitro prearteriolar vessels determined with a video system. Ann Biomed Eng 12:463-479.
    • (1984) Ann Biomed Eng , vol.12 , pp. 463-479
    • Halpern, W.1    Osol, G.2    Coy, G.S.3
  • 19
    • 0003131905 scopus 로고    scopus 로고
    • The pharmacology of sibutramine, the first serotonin and noradrenaline reuptake inhibitor to be developed for the treatment of obesity
    • Heal DJ and Cheetham SC (1997) The pharmacology of sibutramine, the first serotonin and noradrenaline reuptake inhibitor to be developed for the treatment of obesity. Lett Pharmacol 11 (Suppl 10):3-8.
    • (1997) Lett Pharmacol , vol.11 , Issue.SUPPL. 10 , pp. 3-8
    • Heal, D.J.1    Cheetham, S.C.2
  • 21
    • 0030860731 scopus 로고    scopus 로고
    • Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat
    • Jackson HC, Needham AM, Hutchins LJ, Mazurkiewicz SE, and Heal DJ (1997) Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat. Br J Pharmacol 121:1758-1762.
    • (1997) Br J Pharmacol , vol.121 , pp. 1758-1762
    • Jackson, H.C.1    Needham, A.M.2    Hutchins, L.J.3    Mazurkiewicz, S.E.4    Heal, D.J.5
  • 22
    • 0025810341 scopus 로고
    • Mechanisms contributing to the differential haemodynamic effects of bombesin and cholecystokinin in conscious, Long-Evans rats
    • Janssen PJJM, Gardiner SM, Compton AM, and Bennett T (1991) Mechanisms contributing to the differential haemodynamic effects of bombesin and cholecystokinin in conscious, Long-Evans rats. Br J Pharmacol 102:123-134.
    • (1991) Br J Pharmacol , vol.102 , pp. 123-134
    • Janssen, P.J.J.M.1    Gardiner, S.M.2    Compton, A.M.3    Bennett, T.4
  • 23
    • 0024205278 scopus 로고
    • Clinical pharmacology of sibutramine hydrochloride (BTS 54524), a new antidepressant, in healthy volunteers
    • King DJ and Devaney N (1988) Clinical pharmacology of sibutramine hydrochloride (BTS 54524), a new antidepressant, in healthy volunteers. Br J Clin Pharmacol 26:607-611.
    • (1988) Br J Clin Pharmacol , vol.26 , pp. 607-611
    • King, D.J.1    Devaney, N.2
  • 24
    • 0028091785 scopus 로고
    • Regional adiposity and morbidity
    • Kissebah AH and Krakower GR (1994) Regional adiposity and morbidity. Physiol Rev 74:761-811.
    • (1994) Physiol Rev , vol.74 , pp. 761-811
    • Kissebah, A.H.1    Krakower, G.R.2
  • 25
    • 0034611791 scopus 로고    scopus 로고
    • Obesity as a medical problem
    • Kopelman PG (2000) Obesity as a medical problem. Nature (Lond) 404:635-643.
    • (2000) Nature (Lond) , vol.404 , pp. 635-643
    • Kopelman, P.G.1
  • 26
    • 0037066583 scopus 로고    scopus 로고
    • The discovery and status of sibutramine as an antiobesity drug
    • Luque CA and Rey JA (2002) The discovery and status of sibutramine as an antiobesity drug. Eur J Pharmacol 440:119-128.
    • (2002) Eur J Pharmacol , vol.440 , pp. 119-128
    • Luque, C.A.1    Rey, J.A.2
  • 27
    • 0024503310 scopus 로고
    • The contribution of metabolites to the rapid and potent down-regulation of rat cortical β-adrenoceptors by the putative antidepressant, sibutramine hydrochloride
    • Luscombe GP, Hopcroft RH, Thomas PC, and Buckett WR (1989) The contribution of metabolites to the rapid and potent down-regulation of rat cortical β-adrenoceptors by the putative antidepressant, sibutramine hydrochloride. Neuropharmacology 28:129-134.
    • (1989) Neuropharmacology , vol.28 , pp. 129-134
    • Luscombe, G.P.1    Hopcroft, R.H.2    Thomas, P.C.3    Buckett, W.R.4
  • 28
    • 0025022589 scopus 로고
    • Effect on radiolabelled-monoamine uptake in vitro of plasma taken from healthy volunteers administered the antidepressant sibutramine HCl
    • Luscombe GP, Slater NA, Lyons MB, Wynne RD, Scheinbaum ML, and Buckett WR (1990) Effect on radiolabelled-monoamine uptake in vitro of plasma taken from healthy volunteers administered the antidepressant sibutramine HCl. Psychopharmacology 100:345-349.
    • (1990) Psychopharmacology , vol.100 , pp. 345-349
    • Luscombe, G.P.1    Slater, N.A.2    Lyons, M.B.3    Wynne, R.D.4    Scheinbaum, M.L.5    Buckett, W.R.6
  • 29
    • 0033775196 scopus 로고    scopus 로고
    • Comparison of the effects of sibutramine and other weight-modifying drugs on extracellular dopamine in the nucleus accumbens of freely moving rats
    • Rowley HL, Butler SA, Prow MR, Dykes SG, Aspley S, Kilpatrick IC, and Heal DJ (2000) Comparison of the effects of sibutramine and other weight-modifying drugs on extracellular dopamine in the nucleus accumbens of freely moving rats. Synapse 38:167-176.
    • (2000) Synapse , vol.38 , pp. 167-176
    • Rowley, H.L.1    Butler, S.A.2    Prow, M.R.3    Dykes, S.G.4    Aspley, S.5    Kilpatrick, I.C.6    Heal, D.J.7
  • 31
    • 0030942814 scopus 로고    scopus 로고
    • Sibutramine: A review of the pharmacology of a novel anti-obesity agent
    • Stock MJ (1997) Sibutramine: a review of the pharmacology of a novel anti-obesity agent. Int J Obes 21:S25-S29.
    • (1997) Int J Obes , vol.21
    • Stock, M.J.1
  • 33
    • 0023160088 scopus 로고
    • Friedman and Quade tests: BASIC computer program to perform nonparametric two-way analysis of variance and multiple comparisons on ranks of several related samples
    • Theodorsson-Norheim E (1987) Friedman and Quade tests: BASIC computer program to perform nonparametric two-way analysis of variance and multiple comparisons on ranks of several related samples. Comput Biol Med 17:85-99.
    • (1987) Comput Biol Med , vol.17 , pp. 85-99
    • Theodorsson-Norheim, E.1
  • 34
    • 26544440011 scopus 로고    scopus 로고
    • Regional haemodynamic responses to fluoxetine or nisoxetine in conscious Sprague-Dawley rats
    • Woolard J, Gardiner SM, Aspley S, and Bennett T (2001) Regional haemodynamic responses to fluoxetine or nisoxetine in conscious Sprague-Dawley rats. Br J Pharmacol 133 (Suppl):27P.
    • (2001) Br J Pharmacol , vol.133 , Issue.SUPPL.
    • Woolard, J.1    Gardiner, S.M.2    Aspley, S.3    Bennett, T.4
  • 35
    • 26544450996 scopus 로고    scopus 로고
    • Regional haemodynamic effects of the 5-HT and noradrenaline re-uptake inhibitor, sibutramine, in conscious rats: Effects of α or β-adrenoceptor antagonism
    • Woolard J, Gardiner SM, Aspley S, and Bennett T (2002) Regional haemodynamic effects of the 5-HT and noradrenaline re-uptake inhibitor, sibutramine, in conscious rats: effects of α or β-adrenoceptor antagonism. Br J Pharmacol 137 (Suppl):76P.
    • (2002) Br J Pharmacol , vol.137 , Issue.SUPPL.
    • Woolard, J.1    Gardiner, S.M.2    Aspley, S.3    Bennett, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.