The Effects of a Polymerized Bovine-Derived Hemoglobin Solution in a Rabbit Model of Arterial Thrombosis and Bleeding

Anesthesia and Analgesia

Volumn 98, Issue 3, 2004, Pages 604-610

  Marret, Emmanuel ^a   Bonnin, Philippe ^b   Mazoyer, Elisabeth ^b   Riou, Bruno ^a   Jacobs, Ted ^c   Coriat, Pierre ^a   Samama, Charles Marc ^d  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b HÔPITAL LARIBOISIÈRE   (France)

^c Biopure Corporation   (United States)

^d AVICENNE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GELATIN; PLASMION; POLYMERIZED HEMOGLOBIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY BLOOD FLOW; ARTERY COMPRESSION; ARTERY INJURY; ARTERY THROMBOSIS; ARTICLE; BLEEDING; BLEEDING TIME; COMMON CAROTID ARTERY; CONTROLLED STUDY; ERYTHROCYTE TRANSFUSION; HEMOSTASIS; MALE; NONHUMAN; OXYGEN TRANSPORT; OXYGENATION; PRIORITY JOURNAL; RABBIT;

EID: 1342309853     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000099366.73625.DD     Document Type: Article

References (31)

1. Goodnough LT, Brecher ME, Kanter MH, AuBuchon JP. Transfusion medicine: first of two parts-blood transfusion. N Engl J Med 1999;340:438-47.
2. Spahn DR, Casutt M. Eliminating blood transfusions: new aspects and perspectives. Anesthesiology 2000;93:242-55.
3. Winslow RM. Blood substitutes: a moving target. Nat Med 1995;1:1212-5.
4. Olsen SB, Tang DB, Jackson MR, et al. Enhancement of platelet deposition by cross-linked hemoglobin in a rat carotid endarterectomy model. Circulation 1996;93:327-32.
5. Lalla FR, Ning J, Chang TM. Effects of pyridoxalated polyhemoglobin and stroma-free hemoglobin on ADP-induced platelet aggregation. Biomater Artif Cells Artif Organs 1989;17:363-9.
6. Simoni J, Simoni G, Wesson DE, et al. A novel hemoglobin-adenosine-glutathione based blood substitute: evaluation of its effects on human blood ex vivo. ASAIO J 2000;46:679-92.
7. Jahr JS, Lurie F, Gosselin R, et al. Effects of hemoglobin glutamer-250 (bovine) (HBOC-201, Hemopure) on coagulation testing. Am J Ther 2002;9:431-6.
8. Callas DD, Clark TL, Moreira PL, et al. In vitro effects of a novel hemoglobin-based oxygen carrier on routine chemistry, therapeutic drug, coagulation, hematology, and blood bank assays. Clin Chem 1997;43:1744-8.
9. Lundsgaard-Hansen P, Tschirren B. Clinical experience with 120,000 units of modified fluid gelatin. Dev Biol Stand 1980;48:251-6.
10. Tabuchi N, de Haan J, Gallandat Huet RC, et al. Gelatin use impairs platelet adhesion during cardiac surgery. Thromb Haemost 1995;74:1447-51.
11. Mardel SN, Saunders F, Ollerenshaw L, et al. Reduced quality of in-vitro clot formation with gelatin-based plasma substitutes [letter]. Lancet 1996;347:825.
12. de Jonge E, Levi M, Berends F, et al. Impaired haemostasis by intravenous administration of a gelatin-based plasma expander in human subjects. Thromb Haemost 1998;79:286-90.
13. Folts JD. Drugs for the prevention of coronary thrombosis: from an animal model to clinical trials. Cardiovasc Drugs Ther 1995;9:31-43.
14. Folts JD, Gallagher K, Rowe GG. Blood flow reductions in stenosed canine coronary arteries: vasospasm or platelet aggregation? Circulation 1982;65:248-55.
15. Folts JD. An in vivo model of experimental arterial stenosis, intimal damage, and periodic thrombosis. Circulation 1991;83(suppl IV):3-1.
16. Delaporte-Cerceau S, Samama CM, Riou B, et al. Ketorolac and enoxaparin affect arterial thrombosis and bleeding in the rabbit. Anesthesiology 1998;88:1310-7.
17. Ouaknine-Orlando B, Samama CM, Riou B, et al. Role of the hematocrit in a rabbit model of arterial thrombosis and bleeding. Anesthesiology 1999;90:1454-61.
18. Lee DH, Bardossy L, Peterson N, Blajchman MA. o-Raffinose cross-linked hemoglobin improves the hemostatic defect associated with anemia and thrombocytopenia in rabbits. Blood 2000;96:3630-6.
19. Groves PH, Lewis MJ, Cheadle HA, Permy WJ. SIN-1 reduces platelet adhesion and platelet thrombus formation in a porcine model of balloon angioplasty. Circulation 1993;87:590-7.
20. Folts JD, Crowell EB Jr, Rowe GG. Platelet aggregation in partially obstructed vessels and its elimination with aspirin. Circulation 1976;54:365-70.
21. Samama CM, Daghfous M, Delaporte-Cerceau S, et al. Comparison of the effects of ketorolac and aspirin on hemostasis in the rabbit. Ann Fr Anesth Reanim 1995;14:393-8.
22. oude Egbrink MG, Tangelder GJ, Slaaf DW, Reneman RS. Effect of blood gases and pH on thromboembolic reactions in rabbit mesenteric microvessels. Pflugers Arch 1989;414:324-30.
23. oude Egbrink MG, Tangelder GJ, Slaaf DW, et al. Influence of hypercapnia and hypoxia on rabbit platelet aggregation. Thromb Res 1990;57:863-75.
24. Michelson AD, MacGregor H, Barnard MR, et al. Reversible inhibition of human platelet activation by hypothermia in vivo and in vitro. Thromb Haemost 1994;71:633-40.
25. Maalej N, Holden JE, Folts JD. Effect of shear stress on acute platelet thrombus formation in canine stenosed carotid arteries: an in vivo quantitative study. J Thromb Thrombolysis 1998;5:231-8.
26. Maalej N, Folts JD. Increased shear stress overcomes the antithrombotic platelet inhibitory effect of aspirin in stenosed dog coronary arteries. Circulation 1996;93:1201-5.
27. Hogman M, Frostell C, Arnberg H, et al. Prolonged bleeding time during nitric oxide inhalation in the rabbit. Acta Physiol Scand 1994;151:125-9.
28. Karoutsos S, Nathan N, Lahrimi A, et al. Thrombelastogram reveals hypercoagulability after administration of gelatin solution. Br J Anaesth 1999;82:175-7.
29. Egli GA, Zollinger A, Seifert B, et al. Effect of progressive haemodilution with hydroxyethyl starch, gelatin and albumin on blood coagulation. Br J Anaesth 1997;78:684-9.
30. Mullon J, Giacoppe G, Clagett C, et al. Transfusions of polymerized bovine hemoglobin in a patient with severe autoimmune hemolytic anemia. N Engl J Med 2000;342:1638-43.
31. Mardel SN, Saunders FM, Allen H, et al. Reduced quality of clot formation with gelatin-based plasma substitutes. Br J Anaesth 1998;80:204-7.