Mitochondrial involvement in RP-1 mediated apoptosis in U 87 cells

Biomedicine and Pharmacotherapy

Volumn 58, Issue 2, 2004, Pages 129-135

  Agrawala, P K ^a   Mittal, A ^a   Bala, M ^a   Goel, H C ^a  

^a INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

Apoptosis; G2 M arrest; Mitochondria; Podophyllum hexandrum

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; HEAT SHOCK PROTEIN 70; PLANT EXTRACT; PROTEIN BCL 2; VERAPAMIL;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL SURVIVAL; CYTOTOXICITY; DRUG EXPOSURE; HUMAN; HUMAN CELL; IRRADIATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PODOPHYLLUM HEXANDRUM; PRIORITY JOURNAL; RHIZOME;

EID: 1342306723     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2003.10.002     Document Type: Article

References (24)

1. Chatterjee A., Pakrashi S.C. The treatise of Indian medicinal plants. 6:1995;130 India: Publication and Information Directorate, CSIR.
2. Blasko G., Cordell G.A. Recent developments in chemistry of plant derived anticancer agents. Wagner H., Hiroshi H., Fransworth N.R. Economic and medicinal plant research. 1998;Academic Press, London.
3. Paulson J.C., McClure W.O. Microtubule and axoplasmic transport. Inhibition of transport by podophyllotoxin: an interaction with microtubule protein. J Cell Biol. 67:1975;461-467.
4. Kamal A., Atchison K., Daneshtalab M., Micetich R.G. Synthesis of podophyllotoxin congeners as potential DNA topoisomerase II inhibitors. Anticancer Drug Design. 10:1995;545-554.
5. Truedsson L., Geborek P., Sturfelt G. Antiproliferative effects on human peripheral blood mononuclear cells and inhibition of in vitro immunoglobulin synthesis by podophyllotoxin (CPH86) and by semisynthetic lignan glycosides (CPH88). Clin Exp Rheumatol. 11:1993;179-182.
6. Canel C., Morases R.M., Dayan F.E., Ferreira D. Podophyllotoxin. Phytochemistry. 54:2000;115-120.
7. Goel H.C., Prasad J., Sharma A. Antitumor and radioprotective action of Podophyllum hexandrum. Indian J Exp Biol. 36:1998;583-587.
8. Mittal A., Pathania V., Agrawala P.K., Prasad J., Singh S., Goel H.C. Influence of Podophyllum hexandrum on endogenous antioxidant defence system in mice: possible role in radioprotection. Ethnopharmacology. 76:2001;253-262.
9. Salin C.A., Samanta N., Goel H.C. Protection of mouse jejunum against lethal irradiation by Podophyllum hexandrum. Phytomedicine. 8:2001;413-422.
10. Samanta N., Goel H.C. Protection against radiation induced damage to spermatogenesis by Podophyllum hexandrum. Ethnopharmacology. 81:2002;217-224.
11. Goel H.C., Agrawala P.K., Pathania V., Malhotra N. Immunomodulatory and cytoprotective role of RP-1 in γ-irradiated mice. Mol Cell Biochem. 254:2003;73-81.
12. Berridge M.V., Tan A.S., McCoy K.D., Wang R. The biochemical and cellular basis of cell proliferation assays that use tetrazolium salts. Biochemica. 4:1996;14-18.
13. Fernandez M.G., Troiano L., Moretti L., Pedrazzi J., Salvioli S., Castilla-Cortazar I., et al. Changes in mitochondrial cardiolipin distribution in apoptosis resistant HCW-2 cells, derived from human promyelocytic leukemia HL-60. FEBS Lett. 478:2000;290-294.
14. Lee H., Yin P., Lu C., Chi C., Wei Y. Increase in mitochondria and mitochondrial DNA in response to oxidative stress in human cells. Biochem J. 348:2000;425-432.
15. Hockenbery D.M., Oltvai Z.N., Yin X., Milliman C.L., Korsmeyer. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell. 75:1993;241-251.
16. Kobayashi T., Nakata T., Kuzumaki T. Effect of flavonoids on cell cycle progression in prostrate cancer cells. Cancer Lett. 176:2002;17-23.
17. Heiden T., Castaños-Vélez E., Andersson L., Biberfeld P. Combined analysis of DNA ploidy, proliferation, and apoptosis in paraffin-embedded cell material by flow cytometry. Lab Investigation. 80:2000;1207-1213.
18. Leslie K.O., Shitamoto B. The bone marrow in systemic podophyllin toxicity. Am J Clin Path. 77:1982;478-480.
19. Gupta D., Arora R., Garg A.P., Goel H.C. Radiation protection of HepG2 cells by Podophyllum hexandrum Royale. Mol Cell Biochem. 250:2003;27-40.
20. Tseng C.J., Wang Y.J., Liang Y.C., Jeng J.H., Lee W.S., Lin J.K., et al. Microtubule damaging agents induce apoptosis in HL-60 cells and G2/M arrest in HT-29 cells. Toxicology. 175:2002;123-142.
21. Porter L.A., Singh G., Lee J.M. Abundance of cyclin B1 regulates γ-radiation-induced apoptosis. Neoplasia. 95:2000;2645-2650.
22. Middleton E., Kandaswami C., Theoharides T.C. The effect of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev. 52:2000;673-751.
23. Kim J.S., Amorino G.P., Pyo H., Cao Q., Choy H. Radiation enhancement by the combined use of topoisomerase I inhibitors RFS-2000 or CPT-11, and topoisomerase II inhibitor etoposide in human lung cancer cells. Radiother Oncol. 62:2002;61-67.
24. Jaattela M. Escaping cell death: survival proteins in cancer. Exp Cell Res. 248:1999;30-43.