Unanticipated Changes in Steady-state mRNA Levels for Glyceraldehyde-3-Phosphate Dehydrogenase in Rat Tibiae

Calcified Tissue International

Volumn 74, Issue 2, 2004, Pages 204-207

  Maran, A ^a   Hefferan, T E ^a   Zhang, M ^a   Turner, R T ^a  

^a MAYO CLINIC   (United States)

Author keywords

Control gene; Glyceraldehyde 3 phosphate dehydrogenase (GAPDH); Mechanical unloading; Rat skeleton

Indexed keywords

COMPLEMENTARY DNA; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; PHOSPHORUS 32; RIBONUCLEASE;

ANIMAL TISSUE; ARTICLE; BONE TURNOVER; CONTROLLED STUDY; ENZYME ASSAY; HINDLIMB; LOADING TEST; MECHANICAL STRESS; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; STEADY STATE; TIBIA;

ANIMALS; BLOTTING, NORTHERN; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HINDLIMB; NUCLEASE PROTECTION ASSAYS; RATS; RATS, INBRED F344; RNA, MESSENGER; STRESS, MECHANICAL; TIBIA; WEIGHT-BEARING;

EID: 1342302337     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-002-1098-2     Document Type: Article

References (25)

1. Turner CH (1998) Three rules for bone adaptation to mechanical stimuli. Bone 23:399-407
2. Turner RT (2000) Invited review: What do we know about the effects of spaceflight on bone? J Appl Physiol 89:840-847
3. Halloran BP, Bikle DD, Cone CM, Morey-Holton E (1988) Glucocorticoids and inhibition of bone formation induced by skeletal unloading. Am J Physiol 255:E875-879
4. Skerry TM (1999) Identification of novel signaling pathways during functional adaptation of the skeleton to mechanical loading: the role of glutamate as a paracrine signaling agent in the skeleton. J Bone Miner Metab 17:66-70
5. Skerry TM, Pead MJ, Lanyon LE (1991) Modulation of bone loss during disuse by pulsed electromagnetic fields. J Orthop Res 9:600-608
6. Westerlind KC, Wronski TJ, Ritman EL, Luo ZP, An KN, Bell NH, Turner RT (1997) Estrogen regulates the rate of bone turnover but bone balance in ovariectomized rats is modulated by prevailing mechanical strain. Proc Natl Acad Sci USA 94:4199-4204
7. Leblanc AD, Schneider VS, Evans HJ, Engelbretson DA, Krebs JM (1990) Bone mineral loss and recovery after 17 weeks of bed rest. J Bone Miner Res 5:843-850
8. Cavolina JM, Evans GL, Harris SA, Zhang M, Westerlind KC, Turner RT (1997) The effects of orbital spaceflight on bone histomorphometry and messenger ribonucleic acid levels for bone matrix proteins and skeletal signaling peptides in ovariectomized growing rats. Endocrinology 138:1567-1576
9. Wronski TJ, Morey ER (1983) Effect of spaceflight on periosteal bone formation in rats. Am J Physiol 244:R305-309
10. Morey-Holton ER, Globus RK (2002) Hindlimb unloading rodent model: technical aspects. J Appl Physiol 92:1367-1377
11. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
12. Turner RT, Wronski TJ, Zhang M, Kidder LS, Bloomfield SA, Sibonga JD (1998) Effects of ethanol on gene expression in rat bone: transient dose-dependent changes in mRNA levels for matrix proteins, skeletal growth factors, and cytokines are followed by reductions in bone formation. Alcohol Clin Exp Res 22:1591-1599
13. Turner RT, Evans GL, Zhang M, Maran A, Sibonga JD (1999) Is resveratrol an estrogen agonist in growing rats? Endocrinology 140:50-54
14. Kidder LS, Schmidt IU, Evans GL, Turner RT (1997) Effects of growth hormone and low dose estrogen on bone growth and turnover in long bones of hypophysectomized rats. Calcif Tissue Int 61:327-335
15. Rose IA, Warms JV (1966) Control of glycolysis in the human red blood cell. J Biol Chem 241:4848-4854
16. Kumar K, Wu XL (1995) Expression of beta-actin and alpha-tubulin mRNA in gerbil brain following transient ischemia and reperfusion up to 1 month. Mol Brain Res 30:149-157
17. Tanner JE, Tosato G (1992) Regulation of B-cell growth and immunoglobulin gene transcription by interleukin-6. Blood 79:452-459
18. Melki SA, Abumrad NA (1993) Expression of the adipocyte fatty acid-binding protein in streptozotocin-diabetes: effects of insulin deficiency and supplementation. J Lipid Res 34:1527-1534
19. Fort P, Marty L, Piechaczyk M, el Sabrouty S, Dani C, Jeanteur P, Blanchard JM (1985) Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Nucleic Acids Res 13:1431-1442
20. Piechaczyk M, Blanchard JM, Marty L, Dani C, Panabieres F, El Sabouty S, Fort P, Jeanteur P (1984) Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues. Nucleic Acids Res 12:6951-6963
21. Fagan T, Morse D, Hastings JW (1999) Circadian synthesis of a nuclear-encoded chloroplast glyceraldehyde-3-phosphate dehydrogenase in the dinoflagellate Gonyaulax polyedra is translationally controlled. Biochemistry 38:7689-7695
22. Shinohara ML, Loros JJ, Dunlap JC (1998) Glyceraldehyde-3-phosphate dehydrogenase is regulated on a daily basis by the circadian clock. J Biol Chem 273:446-452
23. Schmidt IU, Dobnig H, Turner RT (1995) Intermittent parathyroid hormone treatment increases osteoblast number, steady state messenger ribonucleic acid levels for osteocalcin, and bone formation in tibial metaphysis of hypophysectomized female rats. Endocrinology 136:5127-5134
24. Turner RT, Kidder LS, Zhang M, Harris SA, Westerlind KC, Maran A, Wronski TJ (1999) Estrogen has rapid tissue-specific effects on rat bone. J Appl Physiol 86:1950-1958
25. Evans GL, Morey-Holton E, Turner RT (1998) Spaceflight has compartment- and gene-specific effects on mRNA levels for bone matrix proteins in rat femur. J Appl Physiol 84:2132-2137