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Volumn 84, Issue 6, 1998, Pages 2132-2137

Spaceflight has compartment- and gene-specific effects on mRNA levels for bone matrix proteins in rat femur

Author keywords

Bone formation; Bone histomorphometry; Northern analysis; Osteoporosis; Weightlessness

Indexed keywords

COLLAGEN TYPE 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; OSTEOCALCIN; OSTEONECTIN;

EID: 0031832645     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1998.84.6.2132     Document Type: Article
Times cited : (29)

References (48)
  • 1
    • 0028223201 scopus 로고
    • Spaceflight results in reduced mRNA levels for tissue specific proteins in the musculoskeletal system
    • Endocrinol. Metab. 29
    • Backup, P., K. Westerlind, S. Harris, T. Spelsberg, B. Kline, and R. Turner. Spaceflight results in reduced mRNA levels for tissue specific proteins in the musculoskeletal system. Am. J. Physiol. 266 (Endocrinol. Metab. 29): E567-E573, 1994.
    • (1994) Am. J. Physiol. , vol.266
    • Backup, P.1    Westerlind, K.2    Harris, S.3    Spelsberg, T.4    Kline, B.5    Turner, R.6
  • 2
    • 0028900946 scopus 로고
    • The molecular response of bone to growth hormone during skeletal unloading: Regional differences
    • Bilde, D. D., J. Harris, B. P. Halloran, P. A. Currier, S. Tanner, and E. Morey-Holton. The molecular response of bone to growth hormone during skeletal unloading: regional differences. Endocrinology 136: 2099-2109, 1995.
    • (1995) Endocrinology , vol.136 , pp. 2099-2109
    • Bilde, D.D.1    Harris, J.2    Halloran, B.P.3    Currier, P.A.4    Tanner, S.5    Morey-Holton, E.6
  • 3
    • 0028191420 scopus 로고
    • Altered skeletal pattern of gene expression in response to spaceflight and hindlimb elevation
    • Endocrinol. Metab. 30
    • Bikle, D. D., J. Harris, B. P. Halloran, and E. Morey-Holton. Altered skeletal pattern of gene expression in response to spaceflight and hindlimb elevation. Am. J. Physiol. 267 (Endocrinol. Metab. 30): E822-E827, 1994.
    • (1994) Am. J. Physiol. , vol.267
    • Bikle, D.D.1    Harris, J.2    Halloran, B.P.3    Morey-Holton, E.4
  • 4
    • 0023625032 scopus 로고
    • Immunocytochemical localization of γ-carboxyglutamic acid-containing proteins (osteocalcin) in rat bone and dentin
    • Camarda, A. J., W. T. Butler, R. D. Finkelman, and A. Nanci. Immunocytochemical localization of γ-carboxyglutamic acid-containing proteins (osteocalcin) in rat bone and dentin. Calcif. Tissue Int. 40: 349-355, 1987.
    • (1987) Calcif. Tissue Int. , vol.40 , pp. 349-355
    • Camarda, A.J.1    Butler, W.T.2    Finkelman, R.D.3    Nanci, A.4
  • 5
    • 0027528356 scopus 로고
    • Immunolocalization of noncollagenous bone matrix proteins in lumbar vertebrae from intact and surgically menopausal Cynomolgus monkeys
    • Carlson, C. S., H. M. Tulli, M. J. Jayo, R. F. Loeser, R. P. Tracy, K. G. Mann, and M. R. Adams. Immunolocalization of noncollagenous bone matrix proteins in lumbar vertebrae from intact and surgically menopausal Cynomolgus monkeys. J. Bone Miner. Res. 8: 71-81, 1993.
    • (1993) J. Bone Miner. Res. , vol.8 , pp. 71-81
    • Carlson, C.S.1    Tulli, H.M.2    Jayo, M.J.3    Loeser, R.F.4    Tracy, R.P.5    Mann, K.G.6    Adams, M.R.7
  • 6
    • 85047680931 scopus 로고    scopus 로고
    • The effects of orbital spaceflight on bone histomorphometry and mRNA levels for bone matrix proteins and skeletal signaling peptides in ovariectomized growing rats
    • Cavolina, J., G. L. Evans, S. A. Harris, M. Zhang, K. C. Westerlind, and R. T. Turner. The effects of orbital spaceflight on bone histomorphometry and mRNA levels for bone matrix proteins and skeletal signaling peptides in ovariectomized growing rats. Endocrinology 138: 1567-1576, 1997.
    • (1997) Endocrinology , vol.138 , pp. 1567-1576
    • Cavolina, J.1    Evans, G.L.2    Harris, S.A.3    Zhang, M.4    Westerlind, K.C.5    Turner, R.T.6
  • 7
    • 0022760002 scopus 로고
    • Isolation of the human gene for the bone gla protein utilizing mouse and rat cDNA clones
    • Celeste, A. L., B. Rosen, J. L. Buecker, R. Kriz, E. A. Wang, and J. M. Wozney. Isolation of the human gene for the bone gla protein utilizing mouse and rat cDNA clones. EMBO J. 5: 1885-1890, 1986.
    • (1986) EMBO J. , vol.5 , pp. 1885-1890
    • Celeste, A.L.1    Rosen, B.2    Buecker, J.L.3    Kriz, R.4    Wang, E.A.5    Wozney, J.M.6
  • 8
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 9
    • 0029116964 scopus 로고
    • Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells
    • Dobnig, H., and R. T. Turner. Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells. Endocrinology 136: 3632-3638, 1995.
    • (1995) Endocrinology , vol.136 , pp. 3632-3638
    • Dobnig, H.1    Turner, R.T.2
  • 11
    • 0022423216 scopus 로고
    • Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate dehydrogenase multigenic family
    • Forti, P., L. Marty, M. Piechaczyk, S. ElSabovty, C. Dane, P. Jeanteur, and J. M. Blanchard. Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate dehydrogenase multigenic family. Nucleic Acids Res. 13: 1431-1442, 1985.
    • (1985) Nucleic Acids Res. , vol.13 , pp. 1431-1442
    • Forti, P.1    Marty, L.2    Piechaczyk, M.3    ElSabovty, S.4    Dane, C.5    Jeanteur, P.6    Blanchard, J.M.7
  • 12
    • 0021731952 scopus 로고
    • 2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D
    • 2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D. Biochemistry 2: 6210-6216, 1984.
    • (1984) Biochemistry , vol.2 , pp. 6210-6216
    • Genovese, C.1    Rowe, D.2    Kream, B.3
  • 13
    • 0005811867 scopus 로고
    • Direct identification of the calcium-binding amino-acid, γ-carboxyglutamate, in mineralized tissue
    • Hauschka, P. V., J. B. Lian, and P. M. Gallop. Direct identification of the calcium-binding amino-acid, γ-carboxyglutamate, in mineralized tissue. Proc. Natl. Acad. Sci. USA 72: 3925-3929, 1975.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 3925-3929
    • Hauschka, P.V.1    Lian, J.B.2    Gallop, P.M.3
  • 14
    • 0027201873 scopus 로고
    • Dissimilar expression patterns for the extracellular matrix proteins osteopontin (OPN) and collagen type 1 in dental tissues and alveolar bone of the neonatal rat
    • Helder, M. N., A. L. Bronckers, and J. H. Woltgens. Dissimilar expression patterns for the extracellular matrix proteins osteopontin (OPN) and collagen type 1 in dental tissues and alveolar bone of the neonatal rat. Matrix 13: 415-425, 1993.
    • (1993) Matrix , vol.13 , pp. 415-425
    • Helder, M.N.1    Bronckers, A.L.2    Woltgens, J.H.3
  • 16
    • 0020727105 scopus 로고
    • Effects of spaceflight on trabecular bone in rats
    • Regulatory Integrative Comp. Physiol. 13
    • Jee, W. S. S., T. J. Wronski, E. R. Morey, and D. B. Kimmel. Effects of spaceflight on trabecular bone in rats. Am. J. Physiol. 244 (Regulatory Integrative Comp. Physiol. 13): R310-R314, 1983.
    • (1983) Am. J. Physiol. , vol.244
    • Jee, W.S.S.1    Wronski, T.J.2    Morey, E.R.3    Kimmel, D.B.4
  • 17
    • 0029120033 scopus 로고
    • Systemic administration of transforming growth factor-beta 2 prevents the impaired bone formation and osteopenia induced by unloading in rats
    • Machwate, M., E. Zerath, X. Holy, M. Hott, D. Godet, A. Lomri, and P. J. Marie. Systemic administration of transforming growth factor-beta 2 prevents the impaired bone formation and osteopenia induced by unloading in rats. J. Clin. Invest. 96: 1245-1253, 1995.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1245-1253
    • Machwate, M.1    Zerath, E.2    Holy, X.3    Hott, M.4    Godet, D.5    Lomri, A.6    Marie, P.J.7
  • 18
    • 0018076154 scopus 로고
    • Inhibition of bone formation during spaceflight
    • Morey, E. R., and D. J. Baylink. Inhibition of bone formation during spaceflight. Science 201: 1138-1141, 1978.
    • (1978) Science , vol.201 , pp. 1138-1141
    • Morey, E.R.1    Baylink, D.J.2
  • 20
    • 0026550137 scopus 로고
    • Distribution of osteonectin mRNA and protein during human embryonic and fetal development
    • Mundlos, S., B. Schwahn, T. Reichert, and B. Zabel. Distribution of osteonectin mRNA and protein during human embryonic and fetal development. J. Histochem. Cytochem. 40: 283-291, 1992.
    • (1992) J. Histochem. Cytochem. , vol.40 , pp. 283-291
    • Mundlos, S.1    Schwahn, B.2    Reichert, T.3    Zabel, B.4
  • 22
    • 0020509916 scopus 로고
    • Relationship between surface, volume and thickness of the iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss
    • Parfitt, A. M., C. H. E. Mathews, A. R. Villanueva, M. Kleesekoper, B. Frame, and D. S. Rao. Relationship between surface, volume and thickness of the iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss. J. Clin. Invest. 72: 1396-1409, 1983.
    • (1983) J. Clin. Invest. , vol.72 , pp. 1396-1409
    • Parfitt, A.M.1    Mathews, C.H.E.2    Villanueva, A.R.3    Kleesekoper, M.4    Frame, B.5    Rao, D.S.6
  • 24
    • 0002043109 scopus 로고    scopus 로고
    • The biochemistry of bone
    • edited by R. Marcus, D. Feldmanm, and J. Kelsey. New York: Academic
    • Robey, P. G., and A. L. Boskey. The biochemistry of bone. In: Osteoporosis, edited by R. Marcus, D. Feldmanm, and J. Kelsey. New York: Academic, 1996, p. 95-104.
    • (1996) Osteoporosis , pp. 95-104
    • Robey, P.G.1    Boskey, A.L.2
  • 26
    • 0022580184 scopus 로고
    • Inhibition of hydroxyapatite crystal growth by bone-specific and other calcium-binding proteins
    • Romberg, R. W., P. G. Werness, B. L. Riggs, and K. G. Mann. Inhibition of hydroxyapatite crystal growth by bone-specific and other calcium-binding proteins. Biochemistry 25: 1176-1180, 1986.
    • (1986) Biochemistry , vol.25 , pp. 1176-1180
    • Romberg, R.W.1    Werness, P.G.2    Riggs, B.L.3    Mann, K.G.4
  • 27
    • 0023032874 scopus 로고
    • Bone maturation and quality of bone material in rats flown on the space shuttle "Spacelab-3 Mission."
    • Simmons, D. J., J. E. Russell, and M. D. Grynpas. Bone maturation and quality of bone material in rats flown on the space shuttle "Spacelab-3 Mission." Bone Miner. 1: 485-493, 1986.
    • (1986) Bone Miner. , vol.1 , pp. 485-493
    • Simmons, D.J.1    Russell, J.E.2    Grynpas, M.D.3
  • 31
    • 0027994669 scopus 로고
    • Cancellous bone turnover in growing rats: Time dependent changes in association between calcein label and osteoblasts
    • Turner, R. T. Cancellous bone turnover in growing rats: time dependent changes in association between calcein label and osteoblasts. J. Bone Miner. Res. 9: 1419-1434, 1994.
    • (1994) J. Bone Miner. Res. , vol.9 , pp. 1419-1434
    • Turner, R.T.1
  • 32
    • 0029051797 scopus 로고
    • Effects of short-term spaceflight and recombinant human growth hormone (rhGH) on bone growth in young rats
    • Turner, R. T. Effects of short-term spaceflight and recombinant human growth hormone (rhGH) on bone growth in young rats. Aviat. Space Environ. Med. 66: 763-769, 1995.
    • (1995) Aviat. Space Environ. Med. , vol.66 , pp. 763-769
    • Turner, R.T.1
  • 33
    • 0026671788 scopus 로고
    • Mechanism of action of estrogen on intramembranous bone formation: Regulation of osteoblast differentiation and activity
    • Turner, R. T., P. Backup, P. H. Sherman, E. Hill, G. L. Evans, and T. C. Spelsberg. Mechanism of action of estrogen on intramembranous bone formation: regulation of osteoblast differentiation and activity. Endocrinology 131: 883-889, 1992.
    • (1992) Endocrinology , vol.131 , pp. 883-889
    • Turner, R.T.1    Backup, P.2    Sherman, P.H.3    Hill, E.4    Evans, G.L.5    Spelsberg, T.C.6
  • 35
    • 0029077184 scopus 로고
    • Spaceflight results in depressed cancellous bone formation in rat humeri
    • Turner, R. T., G. L. Evans, and G. K. Wakley. Spaceflight results in depressed cancellous bone formation in rat humeri. Aviat. Space Environ. Med. 66: 770-774, 1995.
    • (1995) Aviat. Space Environ. Med. , vol.66 , pp. 770-774
    • Turner, R.T.1    Evans, G.L.2    Wakley, G.K.3
  • 36
    • 0026787616 scopus 로고
    • Tissue-specific expression of bone proteins in femora of growing rats
    • Endocrinol. Metab. 26
    • Turner, R. T., S. Kapelner, and T. C. Spelsberg. Tissue-specific expression of bone proteins in femora of growing rats. Am. J. Physiol. 263 (Endocrinol. Metab. 26): E724-E729, 1992.
    • (1992) Am. J. Physiol. , vol.263
    • Turner, R.T.1    Kapelner, S.2    Spelsberg, T.C.3
  • 37
    • 0026040786 scopus 로고
    • Correlation between mRNA levels for bone cell proteins and bone formation in long bones of maturing rats
    • Endocrinol. Metab. 24
    • Turner, R. T., and T. C. Spelsberg. Correlation between mRNA levels for bone cell proteins and bone formation in long bones of maturing rats. Am. J. Physiol. 261 (Endocrinol. Metab. 24): E348-E353, 1991.
    • (1991) Am. J. Physiol. , vol.261
    • Turner, R.T.1    Spelsberg, T.C.2
  • 38
    • 17744417386 scopus 로고
    • Effects of gravitational loading on bone formation in growing rats
    • Turner, R. T., G. K. Wakley, and B. Szukalski. Effects of gravitational loading on bone formation in growing rats. Physiologist 28: 567-568, 1985.
    • (1985) Physiologist , vol.28 , pp. 567-568
    • Turner, R.T.1    Wakley, G.K.2    Szukalski, B.3
  • 40
    • 0029360709 scopus 로고
    • Hindlimb suspension diminishes femoral cross-sectional growth in the rat
    • Van der Meulen, M. C. H., E. R. Morey-Holton, and D. R. Carter. Hindlimb suspension diminishes femoral cross-sectional growth in the rat. J. Orthop. Res. 13: 700-707, 1995.
    • (1995) J. Orthop. Res. , vol.13 , pp. 700-707
    • Van Der Meulen, M.C.H.1    Morey-Holton, E.R.2    Carter, D.R.3
  • 41
    • 0023080547 scopus 로고
    • Effects of weightlessness on bone mass and osteoclast number in pregnant rats after a five-day spaceflight (Cosmos 1514)
    • Vico, L., D. Chappard, C. Alexandre, S. Palle, P. Minaire, G. Riffat, V. E. Novikov, and A. V. Bakulum. Effects of weightlessness on bone mass and osteoclast number in pregnant rats after a five-day spaceflight (Cosmos 1514). Bone 8: 95-103, 1987.
    • (1987) Bone , vol.8 , pp. 95-103
    • Vico, L.1    Chappard, D.2    Alexandre, C.3    Palle, S.4    Minaire, P.5    Riffat, G.6    Novikov, V.E.7    Bakulum, A.V.8
  • 42
    • 0023805288 scopus 로고
    • Trabecular bone remodeling after seven days of weightlessness exposure (Biocosmos 1667)
    • Regulatory Integrative Comp. Physiol. 24
    • Vico, L., D. Chappard, S. Palle, A. U. Bakulin, V. E. Novikov, and C. Alexandre. Trabecular bone remodeling after seven days of weightlessness exposure (Biocosmos 1667). Am. J. Physiol. 255 (Regulatory Integrative Comp. Physiol. 24): R243-R247, 1988.
    • (1988) Am. J. Physiol. , vol.255
    • Vico, L.1    Chappard, D.2    Palle, S.3    Bakulin, A.U.4    Novikov, V.E.5    Alexandre, C.6
  • 43
    • 0024400783 scopus 로고
    • Structure of human osteonectin based upon analysis of cDNA and genomic sequences
    • Villarreal, X. C., K. G. Mann, and G. L. Long. Structure of human osteonectin based upon analysis of cDNA and genomic sequences. Biochemistry 28: 6483-6491, 1989.
    • (1989) Biochemistry , vol.28 , pp. 6483-6491
    • Villarreal, X.C.1    Mann, K.G.2    Long, G.L.3
  • 44
    • 0027076672 scopus 로고
    • Disuse osteopenia is accompanied by downregulation of gene expression for bone proteins in growing rats
    • Endocrinol. Metab. 26
    • Wakley, G. K., J. S. Portwood, and R. T. Turner. Disuse osteopenia is accompanied by downregulation of gene expression for bone proteins in growing rats. Am. J. Physiol. 263 (Endocrinol. Metab. 26): E1029-E1034, 1992.
    • (1992) Am. J. Physiol. , vol.263
    • Wakley, G.K.1    Portwood, J.S.2    Turner, R.T.3
  • 45
    • 0029015762 scopus 로고
    • The skeletal effects of spaceflight in growing rats: Reduced steady-state mRNA levels of TGF-β
    • Westerlind, K. C., and R. T. Turner. The skeletal effects of spaceflight in growing rats: reduced steady-state mRNA levels of TGF-β. J. Bone Miner. Res. 10: 843-848, 1995.
    • (1995) J. Bone Miner. Res. , vol.10 , pp. 843-848
    • Westerlind, K.C.1    Turner, R.T.2
  • 46
    • 0027141885 scopus 로고
    • Estrogen does not increase bone formation in growing rats
    • Westerlind, K. C., G. K. Wakley, G. L. Evans, and R. T. Turner. Estrogen does not increase bone formation in growing rats. Endocrinology 133: 2924-2934, 1993.
    • (1993) Endocrinology , vol.133 , pp. 2924-2934
    • Westerlind, K.C.1    Wakley, G.K.2    Evans, G.L.3    Turner, R.T.4
  • 47
    • 0020728979 scopus 로고
    • Effects of spaceflight on periosteal bone formation in rats
    • Regulatory Integrative Comp. Physiol. 13
    • Wronski, T. J., and E. R. Morey. Effects of spaceflight on periosteal bone formation in rats. Am. J. Physiol. 244 (Regulatory Integrative Comp. Physiol. 13): R305-R309, 1983.
    • (1983) Am. J. Physiol. , vol.244
    • Wronski, T.J.1    Morey, E.R.2
  • 48
    • 0030056499 scopus 로고    scopus 로고
    • Effects of spaceflight and recovery on rat humeri and vertebrae: Histological and cell culture studies
    • Zerath, E., D. Godet, X. Holly, C. Andre, S. Renault, M. Hott, and P. J. Marie. Effects of spaceflight and recovery on rat humeri and vertebrae: histological and cell culture studies. J. Appl. Physiol. 81: 164-171, 1996.
    • (1996) J. Appl. Physiol. , vol.81 , pp. 164-171
    • Zerath, E.1    Godet, D.2    Holly, X.3    Andre, C.4    Renault, S.5    Hott, M.6    Marie, P.J.7


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