Hippocampal afterdischarges after GABAB-receptor blockade in the freely moving rat

Epilepsia

Volumn 46, Issue 2, 2005, Pages 203-216

  Leung, L Stan ^a   Canning, Kevin J ^a,b   Shen, Bixia ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b GLAXOSMITHKLINE   (Canada)

Author keywords

CGP35348; Gamma waves; Kindling; Paired pulse depression; Theta rhythm

Indexed keywords

3 AMINOPROPYL(DIETHOXYMETHYL)PHOSPHINIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; BENZYL[3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; CGP 55699; UNCLASSIFIED DRUG;

AFTERDISCHARGE; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ARTICLE; BRAIN DEPTH STIMULATION; CLONUS; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; ELECTROPHYSIOLOGY; ENTORHINAL CORTEX; EVOKED CORTICAL RESPONSE; HIPPOCAMPUS; MALE; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE SUSCEPTIBILITY;

ANIMALS; BEHAVIOR, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; ELECTROPHYSIOLOGY; EVOKED POTENTIALS; GABA ANTAGONISTS; HIPPOCAMPUS; INJECTIONS, SPINAL; KINDLING, NEUROLOGIC; MALE; MOTOR ACTIVITY; NEOCORTEX; ORGANOPHOSPHORUS COMPOUNDS; RATS; RATS, LONG-EVANS; RECEPTORS, GABA-B; SEIZURES; THETA RHYTHM;

EID: 13244282940     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0013-9580.2005.35804.x     Document Type: Article

References (55)

1. Krnjevic K. Significance of GABA in brain function. In: Tunnicliff G, Raess BU, eds. GABA mechanisms in epilepsy. New York: Wiley, 1991:47-87.
2. Engel JJ. Excitation and inhibition in epilepsy. Can J Neurol Sci 1996;23:167-74.
3. Snead OC III. Basic mechanisms of generalized absence seizures. Ann Neurol 1995;37:146-57.
4. Bowery NG, Bettler B, Froestl W, et al. International Union of Pharmacology. XXXIII: Mammalian gamma-aminobutyric acid(B) receptors: structure and function. Pharmacol Rev 2002;54:247-64.
5. B receptor antagonists on absences and convulsive seizures. Eur J Pharmacol 1997;332:245-55.
6. Badran S, Schmutz M, Olpe HR. Comparative in vivo and in vitro studies with the potent GABAB receptor antagonist, CGP 56999A. Eur J Pharmacol 1997;333:135-42.
7. Vergnes M, Boehrer A, Reibel S, et al. Selective susceptibility to inhibitors of GABA synthesis and antagonists of GABAA receptor in rats with genetic absence epilepsy. Exp Neurol 2000;161:714-23.
8. Malouf AT, Robbins CA, Schwartzkroin PA. Baclofen inhibition of the slow inhibitory postsynaptic potential in hippocampal slice cultures: a possible role for the GABAB-mediated inhibitory post-synaptic potential. Neuroscience 1990;35:53-61.
9. Uusisaari M, Smirnov S, Voipio J, et al. Spontaneous epileptiform activity mediated by GABAA receptors and gap junctions in the rat hippocampal slice following long-term exposure to GABAB antagonists. Neuropharmacology 2002;43:563-72.
10. Gambardella A, Manna I, Labate A, et al. GABA(B) receptor 1 polymorphism (G1465A) is associated with temporal lobe epilepsy. Neurology 2003;60:560-3.
11. Prosser HM, Gill CH, Hirst WD, et al. Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice. Mol Cell Neurosci 2001;17:1059-70.
12. Schuler V, Luscher C, Blanchet C, et al. Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)). Neuron 2001;31:47-58.
13. Paxinos G, Watson C. The rat brain in stereotaxic coordinates. San Diego: Academic Press, 1986.
14. Davies CH, Starkey SJ, Pozza MF, et al. GABA autoreceptors regulate the induction of LTP. Nature 1991;349:609-11.
15. Karlsson G, Kolb C, Hausdorf A, et al. GABAB receptors in various in vitro and in vivo models of epilepsy: a study with the GABAB receptor blocker CGP 35348. Neuroscience 1992;47:63-8.
16. Davies CH, Pozza MF, Collingridge GL. CGP 55845A: a potent antagonist of GABAB receptors in the CA1 region of rat hippocampus. Neuropharmacology 1993;32:1071-3.
17. Leung LS. Hippocampal electrical activity following local tetanization, I: afterdischarges. Brain Res 1987;419:173-87.
18. Leung LS, Wu C, Wu K, Shen B, et al. Long-lasting behavioral and electrophysiological effects induced by partial hippocampal kindling. In: Corcoran ME, Moshe S, eds. Kindling 5. New York: Plenum Press, 1998:395-408.
19. Racine RJ. Modification of seizure activity by electrical stimulation, II: motor seizure. Electroencephalogr Clin Neurophysiol 1972;32:281-94.
20. Leung LS, Lopes da Silva FH, Wadman WJ. Spectral characteristics of the hippocampal EEG in the freely moving rat. Electroencephalogr Clin Neurophysiol 1982;54:203-19.
21. Kloosterman F, Peloquin P, Leung LS. Apical and basal orthodromic population spikes in hippocampal CA1 in vivo show different origins and patterns of propagation. J Neurophysiol 2001;86:2435-44.
22. Ma J, Leung LS. Medial septum mediates the increase in postictal behaviors and hippocampal gamma waves after an electrically induced seizure. Brain Res 1999;833:51-7.
23. Leung LS. Nonlinear feedback model of neuronal populations in hippocampal CA1 region. J Neurophysiol 1982;47:845-68.
24. Jefferys JGR, Traub RD, Whittington MA. Neuronal networks for induced "40 Hz" rhythms. Trends Neurosci 1996;19:202-8.
25. Traub RD, Jefferys JG, Whittington MA. Simulation of gamma rhythms in networks of interneurons and pyramidal cells. J Comput Neurosci 1997;4:141-50.
26. Leung LS. Generation of theta and gamma rhythms in the hippocampus. Neurosci Biobehav Rev 1998;22:275-90.
27. Leung LS. Spectral analysis of hippocampal EEG in the freely moving rat: effects of centrally active drugs and relations to evoked potentials. Electroencephalogr Clin Neurophysiol 1985;60:65-77.
28. Richards DA, Morrone LA, Bowery NG. Hippocampal extracellular amino acids and EEG spectral analysis in a genetic rat model of absence epilepsy. Neuropharmacology 2000;39:2433-41.
29. Bragin A, Csicsvari J, Penttonen M, et al. Epileptic afterdischarge in the hippocampal-entorhinal system: current source density and unit studies. Neuroscience 1997;76:1187-203.
30. Ma J, Brudzynski SM, Leung LS. A role of subicular and hippocampal afterdischarges in initiation of locomotor activity in rats. Brain Res 1998;793:112-8.
31. Traub RD, Borck C, Colling SB, et al. On the structure of ictal events in vitro. Epilepsia 1996;37:879-91.
32. Konopacki J, MacIver MB, Bland BH, et al. Carbachol-induced EEG "theta" activity in hippocampal brain slices. Brain Res 1987;405:196-8.
33. Konopacki J, Golebiewski H, Eckersdorf B, et al. Theta-like activity in hippocampal formation slices: the effect of strong disinhibition of GABAA and GABAB receptors. Brain Res 1997;775:91-8.
34. Leung LS, Yim CY. Intrinsic membrane potential oscillations in hippocampal neurons in vitro. Brain Res 1991;553:261-74.
35. Cobb SR, Buhl EH, Halasy K, et al. Synchronization of neuronal activity in hippocampus by individual GABAergic imerneurons. Nature 1995;378:75-8.
36. Leung LS. Theta rhythm during REM sleep and waking: correlations between power, phase and frequency. Electroencephalogr Clin Neurophysiol 1984;58:553-64.
37. Scanziani M. GABA spillover activates postsynaptic GABAB receptors to control rhythmic hippocampal activity. Neuron 2000;25:673-81.
38. Vanderwolf CH. Hippocampal electrical activity and voluntary movement in the rat. Electroencephalogr Clin Neurophysiol 1969;26:407-18.
39. Whishaw IQ, Vanderwolf CH. Hippocampal EEG and behavior: changes in amplitude and frequency of RSA (theta rhythm) associated with spontaneous and learned movement patterns in rats and cats. Behav Biol 1973;8:461-84.
40. Racine R, Rose PA, Burnham WM. Afterdischarge thresholds and kindling rates in dorsal and ventral hippocampus and dentate gyrus. Can J Neurol Sci 1977;4:273-8.
41. Leung LS, Boon KA. Kindling in the posterior cingulate cortex: electrographic and behavioural characteristics. Electroencephalogr Clin Neurophysiol 1990;76:177-86.
42. Ziakopoulos Z, Brown MW, Bashir ZI. GABAB receptors mediate frequency-dependent depression of excitatory potentials in rat perirhinal cortex in vitro. Eur J Neurosci 2000;12:803-9.
43. Yeckel MF, Berger TW. Spatial distribution of potentiated synapses in hippocampus: dependence on cellular mechanisms and network properties. J Neurosci 1998;18:438-50.
44. Karlsson G, Klebs K, Hafner T, et al. Blockade of GABAB receptors accelerates amygdala kindling development. Experientia 1992;48:748-51.
45. Gale K. Subcortical structures and pathways involved in convulsive seizure generation. J Clin Neurophysiol 1992;9:264-77.
46. Browning R, Maggio R, Sahibzada N, et al. Role of brainstem structures in seizures initiated from the deep prepiriform cortex of rats. Epilepsia 1993;34:393-407.
47. Goddard GV, McIntyre DC, Leech CK. A permanent change in brain function resulting from daily electrical stimulation. Exp Neurol 1969;25:295-330.
48. Brucato FH, Morrisett RA, Wilson WA, et al. The GABAB receptor antagonist, CGP-35348, inhibits paired-pulse disinhibition in the rat dentate gyrus in vivo. Brain Res 1992;588:150-3.
49. Canning KJ, Leung LS. Excitability of rat dentate gyrus granule cells in vivo is controlled by tonic and evoked GABA(B) receptor-mediated inhibition. Brain Res 2000;863:271-5.
50. Leung LS, Fu X. Factors affecting paired-pulse facilitation in hippocampal CA1 neurons in vitro. Brain Res 1994;650:75-84.
51. Forti M, Michelson HB. Synaptic connectivity of distinct hilar interneuron subpopulations. J Neurophysiol 1998;79:3229-37.
52. Buckmaster PS, Jongen-Relo AL, Davari SB, et al. Testing the disinhibition hypothesis of epileptogenesis in vivo and during spontaneous seizures. J Neurosci 2000;20:6232-40.
53. Buckmaster PS, Wong EH. Evoked responses of the dentate gyrus during seizures in developing gerbils with inherited epilepsy. J Neurophysiol 2002;88:783-93.
54. Tuff LP, Racine RJ, Adamec R. The effects of kindling on GABA-mediated inhibition in the dentate gyrus of the rat, I: Paired-pulse depression. Brain Res 1983;277:79-90.
55. Getova DP, Bowery NG. Effects of high-affinity GABAB receptor antagonists on active and passive avoidance responding in rodents with gamma- hydroxybutyrolactone-induced absence syndrome. Psychopharmacology (Berl) 2001;157:89-95.