Epileptic afterdischarge in the hippocampal-entorhinal system: Current source density and unit studies

Neuroscience

Volumn 76, Issue 4, 1997, Pages 1187-1203

  Bragin, A ^a,b   Csicsvari J ^a   Penttonen, M ^a,c   Buzsaki G ^a  

^a RUTGERS UNIVERSITY   (United States)

^b INSTITUTE OF THEORETICAL AND EXPERIMENTAL BIOPHYSICS   (Russian Federation)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

entorhinal cortex; epilepsy; inhibition; interneurons; oscillations

Indexed keywords

AFTERDISCHARGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; ELECTROPHYSIOLOGY; ENTORHINAL CORTEX; EPILEPSY; FEMALE; HIPPOCAMPUS; HISTOLOGY; INTERNEURON; MALE; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; DENTATE GYRUS; ELECTRIC STIMULATION; ELECTRODES; ELECTROPHYSIOLOGY; ENTORHINAL CORTEX; EPILEPSY; FEEDBACK; FEMALE; HIPPOCAMPUS; INTERNEURONS; MALE; NEURAL PATHWAYS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031012741     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(96)00446-0     Document Type: Article

References (63)

1. Amaral D. and Witter M. (1989) The three-dimensional organization of the hippocampal formation: a review of anatomical data. Neuroscience 31, 571-591.
2. Anderson W. W., Lewis D. V., Schwartzwelder H. S. and Wilson W. A. (1986) Magnesium-free medium activates seizure-like events in the rat hippocampal slice. Brain Res. 398, 215-219.
3. Babb T. L., Pretorius J. K., Kupfer W. R. and Crandall P. H. (1989) Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus. J. Neurosci. 9, 2562-2574.
4. Ben-Ari Y., Krnjevic K. and Reinhardt W. (1979) Hippocampal seizures and failure of inhibition. Can. J. Physiol. Pharmac. 57, 1462-1466.
5. Bragin A., Jandó G., Nádasdy Z., Hetke J., Wise K. and Buzsáki G. (1995) Gamma (40-100 Hz) oscillation in the hippocampus of the behaving rat. J. Neurosci. 15, 47-60.
6. Bragin A., Jandó G., Nádasdy Z., van Landeghem M. and Buzsáki G. (1995) Dentate EEG spikes and associated interneuronal population bursts in the hippocampal hilar region of the rat. J. Neurophysiol. 73, 1691-1705.
7. Buckmaster P. S., Strowbridge B. W., Kunkel D. D., Schmiege D. L. and Schwartzkroin P. A. (1992) Mossy cell axonal projections to the dentate gyrus molecular layer in the rat hippocampal slice. Hippocampus 2, 349-362.
8. Buhl E. H., Han Z. S., Lorinczi Z., Stezhka V. V. and Somogyi P. (1993) Physiological properties of anatomically identified axo-axonic cells in the rat hippocampus. J. Neurophysiol. 111, 222-333.
9. Buzsáki G., Ponomareff L. G., Bayardo F., Ruiz R. and Gage F. H. (1989) Neuronal activity in the subcortically denervated hippocampus: a chronic model for epilepsy. Neuroscience 28, 527-538.
10. Buzsáki G., Hsu M., Slamka C., Gage F. H. and Horvath Z. (1991) Emergence and propagation of interictal spikes in the subcortically denervated hippocampus. Hippocampus 1, 163-180.
11. Buzsáki G. and Eidelberg E. (1982) Direct afferent excitation and long-term potentiation of hippocampal interneurons. J. Neurophysiol. 48, 597-607.
12. Buzsáki G., Leung L. and Vanderwolf C. H. (1983) Cellular bases of hippocampal EEG in the behaving rat. Brain Res. Rev. 6, 139-171.
13. Deadwyler S. A., West J. R., Cotman C. W. and Lynch G. (1975) Physiological studies of the reciprocal connections between the hippocampus and entorhinal cortex. Expl Neurol. 49, 35-57.
14. Dunwiddie T. V. and Haas H. (1985) Adenosine increases synaptic facilitation in the in vitro rat hippocampus: evidence for a presynaptic site of action. J. Physiol. 369, 365-377.
15. During M. J., Ryder K. M. and Spencer D. D. (1995) Hippocampal GABA transporter function in temporal-lobe epilepsy. Nature 376, 174-177.
16. Engel J. Jr (1989) Seizures and Epilepsy. F. A. Davis, Philadelphia.
17. Fernandez de Lima V. M., Pijn J. P., Filipe C. N. and Lopes da Silva F. (1990) The role of hippocampal commissures in the interhemispheric transfer of epileptiform afterdischarges in the rat: a study using linear and non-linear regression analysis. Electroenceph. clin. Neurophysiol. 76, 520-539.
18. Fox S. E. and Ranck J. B. Jr. (1981) Electrophysiological characteristics of hippocampal complex-spike cells and theta cells. Expl Brain Res. 41, 299-313.
19. Freeman J. A. and Nicholson C. (1975) Experimental optimization of current source-density technique for anuran cerebellum. J. Neurophysiol. 38, 369-382.
20. Gallyas F., Hsu M. and Buzsáki G. (1993) Four modified silver methods for thick sections of formaldehyde-fixed mammalian central nervous tissue: dark neurons, perikarya of all cells, microglial cells and capillaries. J. Neurosci. Meth. 50, 159-164.
21. Gloor P., Vera C. L., Sperti L. and Ray S. N. (1961) Investigation of the mechanism of epileptic discharge in the hippocampus. Epilepsia 2, 42-62.
22. Holsheimer J. (1987) Electrical conductivity of the hippocampal CA1 layers and application to current source density analysis. Expl Brain Res. 67, 402-410.
23. Jefferys J. G. R. and Haas H. L. (1982) Synchronized bursting of CA1 hippocampal pyramidal cells in the absence of synaptic transmission. Nature 300, 448-450.
24. Jones R. S. G. (1993) Entorhinal-hippocampal connections: a speculative view of their function. Trends Neurosci. 16, 58-64.
25. A-mediated inhibitory postsynaptic current. J. Neurophysiol. 71, 1128-1138.
26. Khazipov R., Bregestovski P. and Ben-Ari Y. (1993) Hippocampal inhibitory interneurons are functionally disconnected from excitatory inputs by anoxia. J. Neurophysiol. 70, 2251-2259.
27. Kneisler T. B. and Dingledine R. (1995) Synaptic input from CA3 pyramidal cells to dentate basket cells in rat hippocampus. J. Physiol. (in press).
28. Kogure S. (1987) Simultaneous recordings from two types of hippocampal nonpyramidal cells during electrically induced paroxysmal discharges. Expl Neurol. 95, 763-767.
29. Leung L. S. (1987) Hippocampal electrical activity following local tetanization. I. Afterdischarges. Brain Res. 419, 173-187.
30. Li X.-G., Somogyi P., Ylinen A. and Buzsáki G. (1994) The hippocampal CA3 network: an in vivo intracellular labeling study. J comp. Neurol. 339, 181-208.
31. Lopes da Silva F. H., Kamphuis W., Van Neerven J. and Pijn J. (1991) Cellular and network mechanisms in the kindling model of epilepsy: the role of GABAergic inhibition and the emergence of strange attractors. In Mechanisms of the Mind (ed. John R.), pp. 115-139. Birkhäuser, Boston.
32. + during spinal epileptiform seizures. Electroenceph. clin. Neurophysiol. 41, 253-267.
33. Lothman E. W. and Williamson J. M. (1992) Influence of electrical stimulus parameters on afterdischarge thresholds in the rat hippocampus. Epilepsy Res. 13, 205-213.
34. McBain C. J. (1994) Hippocampal inhibitory neuron activity in the elevated potassium model of epilepsy. J. Neurophysiol. 72, 1-11.
35. McNamara J. O. (1994) Cellular and molecular basis of epilepsy. J. Neurosci. 14, 3413-3425.
36. Michelson H. B. and Wong R. K. S. (1991) Excitatory synaptic responses mediated by GABA receptors in the hippocampus. Science 253, 1420-1423.
37. Miles R. and Poncer J.-C. (1993) Metabotropic glutamate receptors mediate a post-tetanic excitation of guinea pig hippocampal inhibitory neurons. J. Physiol. 463, 461-473.
38. Mody I. (1993) The molecular basis of kindling. Brain Pathol. 3, 395-403.
39. Moody W. J., Futamachi K. J. and Prince D. A. (1974) Extracellular potassium activity during epileptogenesis. Expl Neurol. 42, 248-263.
40. Paré D., DeCurtis M. and Llinas R. (1992) Role of the hippocampal-entorhinal loop in temporal lobe epilepsy: extra-and intracellular study in the isolated guinea pig brain in vitro. J. Neurosci. 12, 1867-1881.
41. Prince D. A. (1978) Neurophysiology of epilepsy. A. Rev. Neurosci. 1, 359-415.
42. Ranck J. B. Jr. (1973) Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats. I. Behavioral correlates and firing repertoires. Expl Neurol. 42, 461-531.
43. Scharfman H. E. (1994) EPSPs of dentate gyrus granule cells during epileptiform bursts of dentate hilar "mossy" cells and area CA3 pyramidal cells in disinhibited rat hippocampal slices. J. Neurosci. 14, 6041-6057.
44. Scharfman H. E. (1994) Synchronization of area CA3 hippocampal pyramidal cells and non-granule cells of the dentate gyrus in bicuculline-treated rat hippocampal slices. Neuroscience 59, 245-257.
45. Scharfman H. E. (1996) Conditions required for polysynaptic excitation of dentate granule cells by area CA3 pyramidal cells in rat hippocampal slices. Neuroscience 72, 655-668.
46. Sik A., Penttonen M., Ylinen A. and Buzsáki G. (1995) Hippocampal CA1 interneurons: an in vivo intracellular labeling study. J. Neurosci. 15, 6651-6665.
47. Sloviter R. S. (1983) "Epileptic" brain damage in rats induced by sustained electrical stimulation of the perforant path. 1. Acute electrophysiological and light microscopic studies. Brain Res. Bull 10, 675-697.
48. Sloviter R. S. (1989) Calcium-binding protein (Calbindin-D28k) and parvalbumin immunocytochemistry: localization in the rat hippocampus with specific reference to the selective vulnerability of hippocampal neurons to seizure activity. J. comp. Neurol. 280, 183-196.
49. Sloviter R. S. (1991) Permanently altered hippocampal structure, excitability and inhibition after experimental status epilepticus in the rat; the "dormant basket cell" hypothesis and its possible relevance to temporal lobe epilepsy. Hippocampus 1, 31-40.
50. Somjen G. G. (1984) Acidification of interstitial fluid in hippocampal formation caused by seizures and spreading depression. Brain Res. 311, 186-188.
51. Somjen G. G., Aitken P. G., Giacchino J. L. and McNamara J. O. (1985) Sustained potential shifts and paroxysmal discharges in hippocampal formation. J. Neurophysiol. 53, 1079-1097.
52. A receptors. Science 269, 977-981.
53. Stasheff S. F., Bragdon A. C. and Wilson W. A. (1985) Induction of epileptiform activity in hippocampal slices by trains of electrical stimuli. Brain Res. 344, 296-302.
54. Stringer J. L. and Lothman E. W. (1992) Reverberatory seizure discharges in hippocampal-parahippocampal circuits. Expl Neurol. 116, 198-203.
55. Stringer J. L. and Lothman E. W. (1992) Bilateral maximal dentate activation is critical for the appearance of an afterdischarge in the dentata gyrus. Neuroscience 46, 309-314.
56. Sutula T., Xiao-Xian J., Cavazos J. and Scott G. (1988) Synaptic reorganization in the hippocampus induced by abnormal functional activity. Science 239, 1147-1150.
57. Thompson S. M. and Gähwiler B. H. (1989) Activity-dependent disinhibition. I. Repetitive stimulation reduces IPSP driving force and conductance in the hippocampus in vitro. J. Neurophysiol. 61, 501-533.
58. Traub R. D. and Miles R. (1991) Neuronal Networks of the Hippocampus. Cambridge University Press.
59. Traub R. D. and Wong R. K. S. (1982) Cellular mechanism of neuronal synchronization in epilepsy. Science 216, 745-747.
60. Traynelis S. F. and Dingledine R. (1988) Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice. J. Neurophysiol. 59, 259-276.
61. Wadman W. J., Juta A. J. A., Kamphuis W. and Somjen G. G. (1992) Current source density analysis of sustained potential shifts associated with electrographic seizures and with spreading depression in rat hippocampus. Brain Res. 570, 85-91.
62. Yaari Y., Konnerth A. and Heinemann U. (1986) Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro. II. Role of extracellular potassium. J. Neurophysiol. 56, 424-437.
63. Ylinen A., Soltész I., Bragin A., Penttonen M., Sik A. and Buzsáki G. (1995) Intracellular correlates of hippocampal theta rhythm in identified pyramidal cells, granule cells, and basket cells. Hippocampus 5, 78-90.