Is cytomegalovirus associated with human colorectal tumorigenesis?

American Journal of Clinical Pathology

Volumn 123, Issue 2, 2005, Pages 244-249

  Akintola Ogunremi, Olaronke ^a   Luo, Qing ^b   He, Tong Chuan ^b   Wang, Hanlin L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

Adenocarcinoma; Adenoma; Colorectal; Cytomegalovirus; Immunohistochemistry; Polymerase chain reaction

Indexed keywords

GENE PRODUCT; VIRUS DNA; VIRUS PROTEIN;

ADENOCARCINOMA; ARTICLE; CARCINOGENESIS; COLITIS; COLON MUCOSA; COLON POLYP; COLORECTAL ADENOMA; COLORECTAL CANCER; CONTROLLED STUDY; HUMAN; HUMAN CYTOMEGALOVIRUS; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RECTUM POLYP; STAINING;

EID: 13244279570     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/9QVRHDJUK6H2TURB     Document Type: Article

References (32)

1. Landis SH, Murray T, Bolden S, et al. Cancer statistics, 1999. CA Cancer J Clin. 1999;49:8-31.
2. Stewart SL, King JB, Thompson TD, et al. Cancer mortality surveillance, United States: 1990-2000. MMWR Surveill Summ. 2004;53:1-108.
3. Harkins L, Volk AL, Samanta M, et al. Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer. Lancet. 2002;360:1557-1563.
4. Kühn JE, Wendland T, Eggers HJ, et al. Quantitation of human cytomegalovirus genomes in the brain of AIDS patients. J Med Virol. 1995;47:70-82.
5. Mocarski ES Jr, Courcelle CT. Cytomegaloviruses and their replication. In: Knipe DM, Howley PM, eds. Fields Virology. Philadelphia, PA: Lippincott Williams & Wilkins; 2001:2629-2673.
6. Singh N, Wannstedt C, Keyes L, et al. Impact of evolving trends in recipient and donor characteristics on cytomegalovirus infection in liver transplant recipients. Transplantation. 2004;77:106-110.
7. Vancikova Z, Dvorak P. Cytomegalovirus infection in immunocompetent and immunocompromised individuals: a review. Curr Drug Targets Immune Endocr Metabol Disord. 2001;1:179-187.
8. Landolfo S, Gariglio M, Gribaudo G, et al. The human cytomegalovirus. Pharmacol Ther. 2003;98:269-297.
9. Doniger J, Muralidhar S, Rosenthal LJ. Human cytomegalovirus and human herpesvirus 6 genes that transform and transactivate. Clin Microbiol Rev. 1999;12:367-382.
10. Kalejta RF, Shenk T. Manipulation of the cell cycle by human cytomegalovirus. Front Biosci. 2002;7:d295-d306.
11. Castillo JP, Kowalik TE HCMV infection: modulating the cell cycle and cell death. Int Rev Immunol. 2004;23:113-139.
12. Hagemeier C, Walker SM, Sissons PJ, et al. The 72K IE1 and 80K IE2 proteins of human cytomegalovirus independently trans-activate the c-fos, c-myc and hsp70 promoters via basal promoter elements. J Gen Virol. 1992;73:2385-2393.
13. Boldogh I, AbuBakar S, Deng CZ, et al. Transcriptional activation of cellular oncogenes fos, jun, and myc by human cytomegalovirus. J Virol. 1991;65:1568-1571.
14. Zhu H, Shen Y, Shenk T. Human cytomegalovirus IE1 and IE2 proteins block apoptosis. J Virol. 1995;69:7960-7970.
15. Muralidhar S, Doniger J, Mendelson E, et al. Human cytomegalovirus mtrII oncoprotein binds to p53 and downregulates p53-activated transcription. J Virol. 1996;70:8691-8700.
16. 1 phase of the cell cycle. J Virol. 2003;77:3451-3459.
17. Kalejta RF, Shenk T. Proteasome-dependent, ubiquitin-independent degradation of the Rb family of tumor suppressors by the human cytomegalovirus pp71 protein. Proc Natl Acad Sci U S A. 2003;100:3263-3268.
18. Kalejta RF, Bechtel JT, Shenk T. Human cytomegalovirus pp71 stimulates cell cycle progression by inducing the proteasome-dependent degradation of the retinoblastoma family of tumor suppressors. Mol Cell Biol. 2003;23:1885-1895.
19. Thompson MP, Kurzrock R. Epstein-Barr virus and cancer. Clin Cancer Res. 2004;10:803-821.
20. Aoki Y, Tosato G. Pathogenesis and manifestations of human herpesvirus-8-associated disorders. Semin Hematol. 2003;40:143-153.
21. Rapp F. Cytomegalovirus and carcinogenesis. J Natl Cancer Inst. 1984;72:783-787.
22. Pass RF. Cytomegalovirus. In: Knipe DM, Howley PM, eds. Fields Virology. Philadelphia, PA: Lippincott Williams & Wilkins; 2001:2675-2705.
23. Huang ES, Roche JK. Cytomegalovirus DNA and adenocarcinoma of the colon: evidence for latent viral infection. Lancet. 1978;1:957-960.
24. Hashiro GM, Horikami S, Loh PC. Cytomegalovirus isolations from cell cultures of human adenocarcinomas of the colon. Intervirology. 1979;12:84-88.
25. Roche JK, Cheung KS, Boldogh I, et al. Cytomegalovirus: detection in human colonic and circulating mononuclear cells in association with gastrointestinal disease. Int J Cancer. 1981;27:659-667.
26. Brichacek B, Hirsch I, Zavadova H, et al. Absence of cytomegalovirus DNA from adenocarcinoma of the colon. Intervirology. 1980;14:223-227.
27. Hart H, Neill WA, Norval M. Lack of association of cytomegalovirus with adenocarcinoma of the colon. Gut. 1982;23:21-30.
28. Ruger R, Fleckenstein B. Cytomegalovirus DNA in colorectal carcinoma tissues. Klin Wochenschr. 1985;63:405-408.
29. Boguszakova L, Hirsch I, Brichacek B, et al. Absence of cytomegalovirus, Epstein-Barr virus, and papillomavirus DNA from adenoma and adenocarcinoma of the colon. Acta Virol. 1988;32:303-308.
30. Cobbs CS, Harkins L, Samanta M, et al. Human cytomegalovirus infection and expression in human malignant glioma. Cancer Res. 2002;62:3347-3350.
31. Samanta M, Harkins L, Klemm K, et al. High prevalence of human cytomegalovirus in prostatic intraepithelial neoplasia and prostatic carcinoma. J Urol. 2003;170:998-1002.
32. Shen Y, Zhu H, Shenk T. Human cytomegalovirus IE1 and IE2 proteins are mutagenic and mediate "hit-and-run" oncogenic transformation in cooperation with the adenovirus E1A proteins. Proc Natl Acad Sci U S A. 1997;94:3341-3345.