Human cytomegalovirus IE1 and IE2 proteins are mutagenic and mediate "hit-and-run" oncogenic transformation in cooperation with the adenovirus E1A proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 7, 1997, Pages 3341-3345

  Shen, Yuqiao ^a   Zhu, Hua ^a   Shenk, Thomas ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

E1A PROTEIN; GLYCOPROTEIN H, CYTOMEGALOVIRUS; GLYCOPROTEIN H, HUMAN CYTOMEGALOVIRUS; GLYCOPROTEIN O, CYTOMEGALOVIRUS; IE1 PROTEIN, CYTOMEGALOVIRUS; IE2 PROTEIN, CYTOMEGALOVIRUS; IMMEDIATE EARLY PROTEIN; MEMBRANE PROTEIN; TRANSACTIVATOR PROTEIN; UL115 PROTEIN, HUMAN HERPESVIRUS 5; VIRUS ENVELOPE PROTEIN; VIRUS PROTEIN;

ANIMAL; ARTICLE; CELL CULTURE; CELL TRANSFORMATION; CHO CELL; HAMSTER; MUTAGENESIS; PHYSIOLOGY; RAT; VIRUS CELL TRANSFORMATION; ADENOVIRUS; ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; CONTROLLED STUDY; CYTOMEGALOVIRUS; HUMAN; HUMAN CELL; IMMEDIATE EARLY GENE; MALIGNANT TRANSFORMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; REGULATORY MECHANISM; VIRUS CARCINOGENESIS;

ADENOVIRUS E1A PROTEINS; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CELL TRANSFORMATION, VIRAL; CELLS, CULTURED; CHO CELLS; CRICETINAE; IMMEDIATE-EARLY PROTEINS; MEMBRANE GLYCOPROTEINS; MUTAGENESIS; RATS; TRANS-ACTIVATORS; VIRAL ENVELOPE PROTEINS; VIRAL PROTEINS;

EID: 0030611773     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.7.3341     Document Type: Article

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