Reduced expression of human mismatch repair genes in adult T-cell leukemia

American Journal of Hematology

Volumn 78, Issue 2, 2005, Pages 100-107

  Morimoto, Hiroaki ^a   Tsukada, Junichi ^a,c   Kominato, Yoshihiko ^b   Tanaka, Yoshiya ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Adult T cell leukemia; Mismatch repair gene

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH3; PROTEIN MSH6;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENE REPRESSION; GENE SEGREGATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MALE; MEIOSIS; MISMATCH REPAIR; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T CELL LEUKEMIA; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATASES; AGED; BASE PAIR MISMATCH; CARRIER PROTEINS; DNA METHYLATION; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUKEMIA-LYMPHOMA, T-CELL, ACUTE, HTLV-I-ASSOCIATED; MALE; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS;

EID: 13244278107     PISSN: 03618609     EISSN: None     Source Type: Journal    
DOI: 10.1002/ajh.20259     Document Type: Article

References (48)

1. Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature 1998;396:643-649.
2. Leach FS, Nicolaides NC, Papadopoulos N, et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993;75:1215-1225.
3. Fishel R, Lescoe MK, Rao MR, et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer Cell 1993;75:1027-1038.
4. Fujii H, Shimada T. Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene. J Biol Chem 1989;264:10057-10064.
5. Palombo F, Gallinari P, Iaccarino I, et al. GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells. Science 1995;268:1912-1914.
6. Papadopoulos N, Nicolaides NC, Liu B, et al. Mutations of GTBP in genetically unstable cells. Science 1995;268:1915-1917.
7. Papadopoulos N, Nicolaides NC, Wei YF, et al. Mutation of a mutL homolog in hereditary colon cancer. Science 1994;263:1625-1629.
8. Bronner CE, Baker SM, Morrison PT, et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994;368:258-261.
9. Lipkin SM, Wang V, Jacoby R, et al. MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability. Nat Genet 2000;24:27-35.
10. Horii A, Han HJ, Sasaki S, Shimada M, Nakamura Y. Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes. Biochem Biophys Res Commun 1994;204:1257-1264.
11. Nicolaides NC, Papadopoulos N, Liu B, et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 1994;371:75-80.
12. Reitmair AH, Schmits R, Ewel A. et al. MSH2 deficient mice are viable and susceptible to lymphoid tumours. Nat Genet 1995;11:64-70.
13. de Wind N, Dekker M, Berns A, Radman M, te Riele H. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell 1995;82:321-330.
14. de Wind N, Dekker M, Claij N, et al. HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions. Nat Genet 1999;23:359-362.
15. Prolla TA, Baker SM, Harris AC, et al. Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair. Nat Genet 1998;18:276-279.
16. + tumor cells. Cell 1993;75:1227-1236.
17. Lynch HT, Krush AJ. Cancer family "G" revisited: 1895-1970. Cancer 1971;27:1505-1511.
18. Law IP, Herberman RB, Oldham RK, Bouzoukis J, Hanson SM, Rhode MC. Familial occurrence of colon and uterine carcinoma and of lymphoproliferative malignancies: clinical description. Cancer 1977;39:1224-1228.
19. Law IP, Hollinshead AC, Whang-Peng J, et al. Familial occurrence of colon and uterine carcinoma and of lymphoproliferative malignancies. II. Chromosomal and immunologic abnormalities. Cancer 1977;39:1229-1236.
20. Love RR. Small bowel cancers, B-cell lymphatic leukemia, and six primary cancers with metastases and prolonged survival in the cancer family syndrome of Lynch. Cancer 1985;55:499-502.
21. Ricciardone MD, Ozcelik T, Cevher B, et al. Human MLH1 deficiency predisposes to hematological malignancy and neurofibromatosis type 1. Cancer Res 1999;59:290-293.
22. Wang Q, Lasset C, Desseigne F, et al. Neurofibromatosis and early onset of cancers in hMLH1-deficient children. Cancer Res 1999;59:294-297.
23. Teruya-Feldstein J, Greene J, Cohen L, Popplewell L, Ellis NA, Offit K. Analysis of mismatch repair defects in the familial occurrence of lymphoma and colorectal cancer. Leuk Lymphoma 2002;43:1619-1626.
24. Hatta Y, Yamada Y, Tomonaga M, Miyoshi I, Said JW, Koeffler HP. Microsatellite instability in adult T-cell leukaemia. Br J Haematol 1998;101:341-344.
25. Hayami Y, Komatsu H, Iida S, et al. Microsatellite instability as a potential marker for poor prognosis in adult T cell leukemia/lymphoma. Leuk Lymphoma 1999;32:345-349.
26. Sakashita A, Hattori T, Miller CW, et al. Mutations of the p53 gene in adult T-cell leukemia. Blood 1992;79:477-480.
27. Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996;93:9821-9826.
28. Yanagisawa Y, Ito E, Iwahashi Y, Akiyama Y, Yuasa Y, Maruyama K. Isolation and characterization of the 5′ region of the human mismatch repair gene hPMS1. Biochem Biophys Res Commun 1998;243:738-743.
29. Zhu YM, Das-Gupta EP, Russell NH. Microsatellite instability and p53 mutations are associated with abnormal expression of the MSH2 gene in adult acute leukemia. Blood 1999;94:733-740.
30. Kotoula V, Hytiroglou P, Kaloutsi V, Barbanis S, Kouidou S, Papadimitriou CS. Mismatch repair gene expression in malignant lymphoproliferative disorders of B-cell origin. Leuk Lymphoma 2002;43:393-399.
31. Palombo F, Iaccarino I, Nakajima E, Ikejima M, Shimada T, Jiricny J. hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. Curr Biol 1996;61:1181-1184.
32. Acharya S, Wilson T, Gradia S, et al. hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. Proc Natl Acad Sci USA 1996;93:13629-13634.
33. Drummond JT, Li GM, Longley MJ, Modrich P. Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells. Science 1995;268:1909-1912.
34. Li GM, Modrich P. Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. Proc Natl Acad Sci USA 1995;92:1950-1954.
35. Raschle M, Marra G, Nystrom-Lahti M, Schar P, Jiricny J. Identification of hMutLβ, a heterodimer of hMLH1 and hPMS1. J Biol Chem 1999;274:32368-32375.
36. Wei Q, Bondy ML, Mao L, et al. Reduced expression of mismatch repair genes measured by multiplex reverse transcription-polymerase chain reaction in human gliomas. Cancer Res 1997;57:1673-1677.
37. Flores RH, Kolodner RD. The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. Proc Natl Acad Sci U S A 1998;95:12404-12409.
38. Liu T, Van H, Kuismanen S, et al. The role of hPMS1 and hPMS2 in predisposing to colorectal cancer. Cancer Res 2001;61:7798-7802.
39. Lowsky R, DeCoteau JF, Reitmair AH, et al. Defects of the mismatch repair gene MSH2 are implicated in the development of murine and human lymphoblastic lymphomas and are associated with the aberrant expression of rhombotin-2 (Lmo-2) and TaI-1 (SCL). Blood 1997;89:2276-2282.
40. Robledo M, Martinez B, Arranz E, et al. Genetic instability of microsatellites in hematological neoplasms. Leukemia 1995;9:960-964.
41. Tasaka T, Lee S, Spira S, et al. Microsatellite instability during the progression of acute myelocytic leukaemia. Br J Haematol 1997;98:219-221.
42. Takeuchi S, Seriu T, Tasaka T, et al. Microsatellite instability and other molecular abnormalities in childhood acute lymphoblastic leukaemia. Br J Haematol 1997;98:134-139.
43. + patients. Nat Med 1995;1:65-68.
44. Uittenbogaard MN, Giebler HA, Reisman D, Nyborg JK. Transcriptional repression of p53 by human T-cell leukemia virus type I Tax protein. J Biol Chem 1995;270:28503-28506.
45. Lubbert M, Miller CW, Kahan J, Koeffler HP. Expression, methylation and chromatin structure of the p53 gene in untransformed and human T-cell leukemia virus type I-transformed human T-lymphocytes. Oncogene 1989;4:643-651.
46. Seedhouse CH, Das-Gupta EP, Russell NH. Methylation of the hMLH1 promoter and its association with microsatellite instability in acute myeloid leukemia. Leukemia 2003;17:83-88.
47. Uehara E, Takeuchi S, Tasaka T, et al. Aberrant methylation in promoter-associated CpG islands of multiple genes in therapy-related leukemia. Int J Oncol 2003;23:693-696.
48. Scott S, Kimura T, Ichinohasama R, et al. Microsatellite mutations of transforming growth factor-beta receptor type II and caspase-5 occur in human precursor T-cell lymphoblastic lymphomas/leukemias in vivo but are not associated with hMSH2 or hMLH1 promoter methylation. Leuk Res 2003;27:23-34.