Characterization of the RokA and HexA broad-substrate-specificity hexokinases from Bacteroides fragilis and their role in hexose and N-acetylglucosamine utilization

Journal of Bacteriology

Volumn 187, Issue 3, 2005, Pages 890-901

  Brigham, Christopher J ^a   Malamy, Michael H ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEXOKINASE; HEXOSAMINE; HEXOSE; MANNOSE; N ACETYLGLUCOSAMINE; N ACETYLNEURAMINIC ACID; PHOSPHOTRANSFERASE; POLYSACCHARIDE; SUGAR;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL STRAIN; BACTERIUM; BACTEROIDES; BACTEROIDES FRAGILIS; BACTEROIDES THETAIOTAOMICRON; CLONING; COMMENSALISM; CYTOPHAGA; DELETION MUTANT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; EUKARYOTE; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC ANALYSIS; GENOTYPE; GLUCOSE UTILIZATION; LARGE INTESTINE; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PHYLOGENY; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN PURIFICATION;

ACETYLGLUCOSAMINE; AMINO ACID SEQUENCE; BACTEROIDES FRAGILIS; BASE SEQUENCE; CONSENSUS SEQUENCE; DNA PRIMERS; ESCHERICHIA COLI; HEXOKINASE; HEXOSES; KINETICS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PLASMIDS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); BACTEROIDES FRAGILIS; BACTEROIDES THETAIOTAOMICRON; CYTOPHAGA; ESCHERICHIA COLI; EUKARYOTA; FLAVOBACTERIUM; NEGIBACTERIA;

EID: 13244273427     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.187.3.890-901.2005     Document Type: Article

References (46)

1. Angata, T., and A. Varki. 2002. Chemical diversity of sialic acids and related alpha-keto acids: an evolutionary perspective. Chem. Rev. 102:439-469.
2. Asensio, C., and M. Ruiz-Amil. 1966. N-acetyl-D-glucosamine kinase, II. Escherichia coli. Methods Enzymol. 9:421-425.
3. Baughn, A. D., and M. H. Malamy. 2002. A mitochondrial-like aconitase in the bacterium Bacteroides fragilis: implications for the evolution of the mitochondrial Krebs cycle. Proc. Natl. Acad. Sci. USA 99:4662-4667.
4. Baughn, A. D., and M. H. Malamy. 2004. Nanaerobes: "strict" anaerobes that grow and benefit from the presence of nanomolar O2. Nature 427:441-444.
5. Bayley, D. P., E. R. Rocha, and C. J. Smith. 2000. Analysis of cepA and other Bacteroides fragilis genes reveals a unique promoter structure. FEMS Microbiol. Lett. 193:149-154.
6. Berger, M., H. Chen, W. Reutter, and S. Hinderlich. 2002. Structure and function of N-acetylglucosamine kinase-identification of two active site cystienes. European J. Biochem. 269:4212-4218.
7. Cardenas, M. L., A. Cornish-Bowden, and T. Ureta. 1998. Evolution and regulatory role of the hexokinases. Biochim. Biophys. Acta 1401:242-264.
8. Chen, H.-C., C.-C. Chang, W.-J. Mau, and L.-S. Yen. 2002. Evaluation of N-acetylchitooligosaccharides as the main carbon source for the growth of intestinal bacteria. FEMS Microbiol. Lett. 209:53-56.
9. Chung, C. T., S. L. Niemela, and R. H. Miller. 1989. One-step preparation of competent Escherichia coli: transformation and storage of bacterial cells in the same solution. Proc. Natl. Acad. Sci. USA 86:2172-2175.
10. Comstock, L. E., M. J. Coyne, A. O. Tzianabos, and D. L. Kasper. 1999. Interstrain variation of the polysaccharide B biosynthesis locus of Bacteroides fragilis: characterization of the region from strain 638R. J. Bacteriol. 181:6192-6196.
11. Comstock, L. E., M. J. Coyne, A. O. Tzianabos, A. Pantosti, A. B. Onderdonk, and D. L. Kasper. 1999. Analysis of a capsular polysaccharide biosynthesis locus of Bacteroides fragilis. Infect. Immun. 67:3525-3532.
12. Cuchural, G. J., M. H. Malamy, and F. P. Tally. 1986. Beta-lactamase-mediated imipenem resistance in Bacteroides fragilis. Antimicrob. Agents Chemother. 30:645-648.
13. Delvalle, J. A., and C. Asensio. 1978. Distribution of adenosine 5′-triphosphate (ATP)-dependent hexose kinases in microorganisms. BioSystems 10:265-282.
14. Dorr, C., M. Zaparty, B. Tjaden, H. Brinkmann, and B. Seibers. 2003. The hexokinase of the hyperthermophile Thermoproteus tenax. J. Biol. Chem. 278:18744-18753.
15. 14 and its potential role in regulating beta-glucanase expression. Microbiology 147:1035-1043.
16. 14 and its sequence conservation with regulatory glucokinases of gram-positive bacteria. Anaerobe 8:69-74.
17. Godoy, V. G., M. M. Dallas, T. A. Russo, and M. H. Malamy. 1993. A role for Bacteroides fragilis neuraminidase in bacterial growth in two model systems. Infect. Immun. 61:4415-4426.
18. Hansen, T., B. Reichstein, R. Schmid, and P. Schonheit. 2002. The first archaeal ATP-dependent glucokinase, from the hyperthermophilic crenarchaeon Aeropyrum pernix, represents a monomeric, extremely thermophilic rok glucokinase with broad hexose specificity. J. Bacteriol. 184:5955-5965.
19. Hansen, T., and P. Schonheit. 2003. ATP-dependent glucokinase from the hyperthermophilic bacterium Thermotoga maritima represents an extremely thermophilic ROK glucokinase with high substrate specificity. FEMS Microbiol. Lett. 226:405-411.
20. Holt, J. G., N. R. Krieg, P. H. A. Sneath, J. T. Staley, and S. T. Williams (ed.). 1994. Bergey's manual of determinative bacteriology, 9th ed., vol. 1. Williams and Wilkins, Baltimore, Md.
21. Holte, J.-V. 1998. Growth of the stress-bearing and shape-maintaining murein sacculus in Escherichia coli. Microbiol. Mol. Biol. Rev. 62:181-203.
22. Hooper, L. V., T. Midtvedt, and J. I. Gordon. 2002. How host-microbial interactions shape the nutrient environment of the mammalian intestine. Annu. Rev. Nutr. 22:283-307.
23. Hylemon, P. B., J. L. Young, R. F. Roadcap, and J. P. V. Phibbs. 1977. Uptake and incorporation of glucose and mannose by whole cells of Bacteroides thetaiotaomicron. Appl. Environ. Microbiol. 34:488-494.
24. Joshi, M. D., and V. Jagannathan. 1966. Hexokinase I. Brain. Methods Enzymol. 9:371-376.
25. Kalka-Moll, W. M., Y. Wang, L. E. Comstock, S. E. Gonzalez, A. O. Tzianabos, and D. L. Kasper. 2001. Immunochemical and biological characterization of three capsular polysaccharides from a single Bacteroides fragilis strain. Infect. Immun. 69:2339-2344.
26. Macy, J., I. Probst, and G. Gottschalk. 1975. Evidence for cytochrome involvement in fumarate reduction and adenosine 5′-triphosphate synthesis by Bacteroides fragilis grown in the presence of hemin. J. Bacteriol. 123:436-442.
27. Mesak, L. R., F. M. Mesak, and M. K. Dahl. 2004. Bacillus subtilis GlcK activity requires cystienes within a motif that discriminates microbial glucokinases into two lineages. BMC Microbiology. 4:6.
28. Meyer, D., C. Schneider-Fresenius, R. Horlacher, R. Peist, and W. Boos. 1997. Molecular characterization of glucokinase from Escherichia coli K12. J. Bacteriol. 179:1298-1306.
29. Nelson, K. E., R. D. Fleischmann, R. T. DeBoy, I. T. Paulsen, D. E. Fouts, J. A. Eisen, S. C. Daugherty, R. J. Dodson, A. S. Durkin, M. Gwinn, D. H. Haft, J. F. Kolonay, W. C. Nelson, T. Mason, L. Tallon, J. Gray, D. Granger, H. Tettelin, H. Dong, J. L. Galvin, M. J. Duncan, F. E. Dewhirst, and C. M. Fraser. 2003. Complete genome sequence of the oral pathogenic bacterium Porphyromonas gingivalis strain W83. J. Bacteriol. 185:5591-5601.
30. Park, J. T. 2001. Identification of a dedicated recycling pathway for anhydro-N-acetylmuramic acid and N-acetylglucosamine derived from Escherichia coli cell wall murein. J. Bacteriol. 183:3842-3847.
31. Postma, P. W., J. W. Lengeler, and G. R. Jacobson. 1993. Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria. Microbiol. Rev. 57:543-594.
32. Reissig, J. L., J. L. Strominger, and L. F. LeLoir. 1955. A modified method for the estimation of N-acetylamino sugars. J. Biol. Chem. 217:959-966.
33. Skarlatos, P., and M. K. Dahl. 1998. The glucose kinase of Bacillus subtilis. J. Bacteriol. 180:3222-3226.
34. Stanley, P. 1984. Glycosylation mutants of animal cells. Annu. Rev. Genet. 18:525-552.
35. Swofford, D. L. 2002. Phylogenetic analysis using parsimony and other methods. Sinauer, Sunderland, Md.
36. Tally, F. P., D. R. Snydman, M. J. Shimell, and M. H. Malamy. 1982. Characterization of pBFTM10, a clindamycin-erythromycin resistance transfer factor from Bacteroides fragilis. J. Bacteriol. 151:686-691.
37. Tang, Y. P., and M. H. Malamy. 2000. Isolation of Bacteroides fragilis mutants with in vivo growth defects by using Tn4400′, a modified Tn4400 transposition system, and a new screening method. Infect. Immun. 68:415-419.
38. Thompson, J. S., and M. H. Malamy. 1990. Sequencing the gene for an imipenem-cefoxitin-hydrolyzing enzyme from Bacteroides fragilis TAL2480 reveals strong similarity between CfiA and Bacillus cereus beta-lactamase II. J. Bacteriol. 172:2584-2593.
39. Titgemeyer, F., J. Reizer, A. Reizer, and H. Saier. 1994. Evolutionary relationships between sugar kinases and transcriptional repressors in bacteria. Microbiology 140:2349-2354.
40. Uehara, T., and J. T. Park. 2004. The N-acetyl-D-glucosamine kinase of Escherichia coli and its role in murein recycling. J. Bacteriol. 186:7273-7279.
41. Varel, V. H., and M. P. Bryant. 1974. Nutritional features of Bacteroides fragilis subsp. fragilis. Appl. Microbiol. 18:251-257.
42. Vimr, E. R., and F. A. Troy. 1985. Identification of an inducible catabolic system for sialic acids (nan) in Escherichia coli. J. Bacteriol. 164:845-853.
43. Wagner, E., S. Marcandier, O. Egeter, J. Deutscher, F. Gotz, and R. Bruckner. 1995. Glucose kinase-dependent catabolite repression in Staphylococcus xylosus. 3. Bacteriol. 177:6144-6152.
44. Woodcock, D. M., P. J. Crowther, J. Doherty, S. Jefferson, E. DeCruz, M. Noyer-Widener, S. S. Smith, M. Z. Michael, and M. W. Graham. 1989. Quantitative evaluation of Escherichia coli host strains for tolerance to cytosine methylation in plasmid and phage recombinants. Nucleic Acids Res. 17:3469-3478.
45. Xu, J., M. K. Bjursell, J. Himrod, S. Deng, L K. Carmichael, H. C. Chiang, L. V. Hooper, and J. I. Gordon. 2003. A genomic view of the human-Bacteroides thetaiotaomicron symbiosis. Science 299:2074-2076.
46. Yarema, K. J., and C. R. Bertozzi. 2001. Characterizing glycosylation pathways. Genome Biol. 2:0004.1-0004.10.