Solid supported synthesis of structurally diverse dihydropyrido[2,3-d] pyrimidines using microwave irradiation

Tetrahedron Letters

Volumn 46, Issue 8, 2005, Pages 1345-1348

  Agarwal, Anu ^a   Chauhan, Prem M S ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Dihydropyrido 2,3 d pyrimidines; Microwave irradiation; Solid support

Indexed keywords

PYRIMIDINE DERIVATIVE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; MICROWAVE IRRADIATION;

EID: 13244272071     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.12.109     Document Type: Article

References (31)

1. E. Lunt, and C.C. Newton A.R. Katritzky C.W. Rees A.J. Boulton A. McKillop Comprehensive Heterocyclic Chemistry Vol. 3 1984 Pergamon Oxford 199 232, 260-261
2. T.K. Bradskaw, and D.W. Hutchinson Chem. Soc. Rev. 6 1977 43 62
3. J. Quiroga, S. Cruz, B. Insuasty, and R. Abonia J. Heterocycl. Chem. 38 2001 53 60
4. A.J. Thakur, P. Saikia, D. Prajapati, and J.S. Sandhu Synlett 2001 1299 1301
5. M.-J. Perez-Perez, E.-M. Pretago, M.-L. Jimeno, and M.-J. Camarasa Synlett 2002 155 157
6. P. Bhuyan, R.C. Boruah, and J.S. Sandhu J. Org. Chem. 55 1990 568 571
7. C.E. Muller, U. Geis, J. Hipp, U. Schobert, W. Frobenius, M. Pawlowski, F. Suzuki, and J. Sandoval-Ramirez J. Med. Chem. 40 1997 4396 4405
8. R. Kumar, and D.L.J. Tyrrell Bioorg. Med. Chem. Lett. 11 2001 2917 2920
9. L. Perreux, and A. Loupy Tetrahedron 57 2001 9199 9223
10. M. Larhed, and A. Hallberg Drug Discovery Today 6 2001 406 416
11. A. Stadler, and C.O. Kappe Eur. J. Org. Chem. 31 2001 919 925
12. M. Alterman, and A.J. Hallberg J. Org. Chem. 65 2000 7984 7989
13. A.P. Combs, S. Saubern, M. Rafalski, and P.Y. Lam Tetrahedron Lett. 40 1999 1597 1599
14. S. Chandrashekhar, M.B. Padmaja, and A. Raja Synlett 1999 1597 1599
15. A.M.L. Hoel, and J. Nielsen Tetrahedron Lett. 40 1999 3941 3944
16. G. Kuster, and H.W. Scheeren Tetrahedron Lett. 41 2000 515 519
17. M. Larshed, G. Lindeberg, and A. Hallberg Tetrahedron Lett. 37 1996 8219 8222
18. M. Kajino, and K. Meguro Heterocycles 31 1990 2153 2161
19. A. Agarwal, and P.M.S. Chauhan Synth. Commun. 2004 34
20. S.K. Srivastava, P.M.S. Chauhan, S.K. Agarwal, A.P. Bhaduri, S.N. Singh, N. Fatima, R.K. Chatterjee, and C. Bose Bioorg. Med. Chem. Lett. 6 1996 2623 2628
21. S.K. Srivastava, A. Agarwal, P.M.S. Chauhan, S.K. Agarwal, A.P. Bhaduri, S.N. Singh, N. Fatima, and R.K. Chatterjee J. Med. Chem. 42 1999 1667 1672
22. S.K. Srivastava, A. Agarwal, P.M.S. Chauhan, S.K. Agarwal, A.P. Bhaduri, S.N. Singh, N. Fatima, and R.K. Chatterjee Bioorg. Med. Chem. 7 1999 1223 1236
23. S.K. Srivastava, P.M.S. Chauhan, A.P. Bhaduri, N. Fatima, and R.K. Chatterjee J. Med. Chem. 43 2000 2275 2279
24. S. Tiwari, P.M.S. Chauhan, A.P. Bhaduri, N. Fatima, and R.K. Chatterjee Bioorg. Med. Chem. Lett. 10 2000 1409 1412
25. S.K. Srivastava, W. Haq, P.K. Murthy, P.M.S. Chauhan, and P.K. Murthy Bioorg. Med. Chem. Lett. 9 1999 1885 1888
26. P.M.S. Chauhan, and A. Kumar Comb. Chem. Highthroughput Screening 5 2002 93 95
27. A. Kumar, S. Sinha, and P.M.S. Chauhan Bioorg. Med. Chem. Lett. 12 2002 667 669
28. S.K. Srivastava, W. Haq, and P.M.S. Chauhan Comb. Chem. Highthroughput Screening 2 1999 33 37
29. S.K. Srivastava, W. Haq, and P.M.S. Chauhan Bioorg. Med. Chem. Lett. 9 1999 965 966
30. A. Stadler, and C.O. Kappe Tetrahedron 57 2001 3915 3920
31. 13C (50 MHz) 189.4, 161.5, 158.5, 150.8, 142.0, 141.8, 137.1, 136.3, 134.6, 132.4, 128.6, 127.8, 126.6, 126.2, 113.7, 61.5, 50.6, 37.4, 29.8, 28.7