Primary nucleotide structure of predominant and alternate splice forms of equine insulin-like growth factor I and their gene expression patterns in tissues

American Journal of Veterinary Research

Volumn 60, Issue 10, 1999, Pages 1234-1241

  Nixon, Alan J ^a   Brower Toland, Brent D ^a   Sandell, Linda J ^b  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PRIMER DNA; SOMATOMEDIN C;

AGING; ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; CARTILAGE; CATTLE; DOG; GENE EXPRESSION; GENETICS; HORSE; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SWINE;

AGING; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARTILAGE; CATTLE; DNA PRIMERS; DOGS; GENE EXPRESSION; HORSES; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MICE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SWINE;

EID: 0033206022     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Daughaday WH, Hall K, Raben MS, et al. Somatomedin: proposed designation for sulfation factor. Nature 1972;235:107.
2. Rotwein P, Folz RJ, Gordon JI. Biosynthesis of human insulin-like growth factor I (IGF-I): the primary translation product of IGF-I mRNA contains an unusual 48-amino acid signal peptide. J Biol Chem 1987;262:11807-11812.
3. Rechler M, Nissley S. Insulin-like growth factors. In: Sporn M, Roberts A, eds. Peptide growth factors and their receptors I. New York: Springer-Verlag Inc. 1990:263-367.
4. Daughaday WH, Rotwein P. Insulin-like growth factor I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr Rev 1989;10:68-91.
5. Rotwein P, Pollock KM, Didier DK, et al. Organization and sequence of the human insulin-like growth factor 1 gene: alternative RNA processing produces two insulin-like growth factor 1 precursor peptides. J Biol Chem 1986;261:4828-4832.
6. Rotwein P Two insulin-like growth factor 1 messenger RNAs are expressed in human liver. Proc Natl Acad Sci U S A 1986;83:77-81.
7. Bell GI, Stempien MM, Fong NM, et al. Sequences of liver cDNAs encoding two different mouse insulin-like growth factor 1 precursors. Nucleic Acids Res 1986;14:7873-7882.
8. Roberts CT, Lasky SR, Lowe WL, et al. Molecular cloning of rat insulin-like growth factor 1 complementary deoxyribonucleic acids: differential messenger ribonucleic acid processing and regulation by growth hormone in extrahepatic tissues. Mol Endocrinol 1987;1:243-248.
9. Luyten FP, Hascall VC, Nissley SP, et al. Insulin-like growth factors maintain steady-state metabolism of proteoglycans in bovine articular cartilage explants. Arch Biochem Biophys 1988;267:416-425.
10. Morales TI. Polypeptide regulators of matrix homeostasis in articular cartilage. In. Kuettner KE, Schleyerbach R, Hascall VC, eds. Articular cartilage and osteoarthritis. New York: Raven Press, 1992;265-279.
11. Tyler JA. Insulin-like growth factor 1 can decrease degradation and promote synthesis of proteoglycan in cartilage exposed to cylokines. Biochem J 1989;260:543-548.
12. Morales TI, Hascall VC. Factors involved in the regulation of proteoglycan metabolism in articular cartilage. Arthritis Rheum 1989;32:1197-1201.
13. Mathews LS, Norstedt G, Palmiter RD. Regulation of insulin-like growth factor 1 gene expression by growth hormone. Proc Natl Acad Sci U S A 1986;83:9343-9347.
14. Roberts CT, Brown AL, Graham DE, et al. Growth hormone regulates the abundance of insulin-like growth factor 1 RNA in adult rat liver. J Biol Chem 1986;261:10025-10028.
15. Baker J, Liu J, Robertson EJ, et al. Role of insulin-like growth factors in embryonic and postnatal growth. Cell 1993;75: 73-82.
16. Matsumoto T, Tsukazaki T, Enomoto H, et al. Effects of interleukin-1B on insulin-like growth factor-I autocrine/paracrine axis in cultured rat articular chondrocytes. Ann Rheum Dis 1994;53:128-133.
17. Sandberg MM. Matrix in cartilage and bone development: current views on the function and regulation of major organic components. Ann Med 1991;23:207-217.
18. Murphy LJ, Bell GI, Friesen HG. Tissue distribution of insulin-like growth factor I and II messenger ribonucleic acid in the adult rat. Endocrinology 1987;120:1279-1282.
19. Han VKM, D'Ercole AJ, Lund PK. Cellular localization of somatomedin (insulin-like growth factor) messenger RNA in the human fetus. Science 1987;236:193-197.
20. McQuillan DJ, Handley CJ, Campbell MA, et al. Stimulation of proteoglycan biosynthesis by serum and insulin-like growth factor-1 in cultured bovine articular cartilage. Biochem J 1986;240:423-430.
21. Tesch GH, Handley CJ, et al. Effects of free and bound insulin-like growth factors on proteoglycan metabolism in articular cartilage explants. J Orthop Res 1992;10:14-22.
22. Vetter U, Zapf J, Heit W, et al. Human fetal and adult chondrocytes: effect of insulin like growth factors I and II, insulin, and growth hormone on clonal growth. J Clin Invest 1986;77:1903-1908.
23. Guenther HL, Guenther HE, Froesch ER, et al. Effect of insulin-like growth factor on collagen and glycosaminoglycan synthesis by rabbit articular chondrocytes in culture. Experientia 1982;38:979-981.
24. Trippel SB, Corvol MT, Dumontier MF, et al. Effect of somatomedin-C/insulin-like growth factor I and growth hormone on cultured growth plate and articular chondrocytes. Ped Res 1989; 25:76-82.
25. van Beuningen HM, Arntz OJ, van den Berg WB. Insulin-like growth factor stimulation of articular chondrocyte proteoglycan synthesis. Availability and responses at different ages. Br J Rheum 1993;32:1037-1043.
26. Rogachefsky RA, Dean DD, Howell DS, et al. Treatment of canine osteoarthritis with insulin-like growth factor-I (IGF-I) and sodium pentosan polysulfate. Osteoarth Cart 1993;1:105-114.
27. McIlwraith CW, Nixon AJ. Joint resurfacing: attempts at repairing articular cartilage defects. In: McIlwraith CW, Trotter GT, eds. Joint disease in the horse. Philadelphia: WB Saunders Co, 1996;317-334.
28. Glisin V, Crkvenjakov R, Byus C. Ribonucleic acid isolated by cesium chloride centrifugation. Biochem 1974;13:2633-2637.
29. Sandell LJ. Isolation and analysis of RNA from connective tissues and cells. In: Haralson MA, Hassell JR, eds. Extracellular matrix: a practical approach. Oxford, England: IRL Press, 1995;329-351.
30. Adams ME, Huang DQ, Yao LY, et al. Extraction and isolation of mRNA from adult articular cartilage. Anal Biochem 1992;202: 89-95.
31. Maniatis T, Fritsch EF, Sambrook J, et al. Molecular cloning: a laboratory manual. 2nd ed. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, 1989.
32. Lowe WL, Roberts CT, Lasky SR, et al. Differential expression of alternative 5′ untranslated regions in mRNAs encoding rat insulin-like growth factor I. Proc Natl Acad Sci U S A 1987;84: 8946-8950.
33. Lowe WL, Lasky SR, LeRoith D, et al. Distribution and regulation of rat insulin-like growth factor I messenger ribonucleic acids encoding alternative carboxyterminal E-peptides: evidence for differential processing and regulation in liver. Mol Endocrinol 1988;2:528-535.
34. Le Bouc Y, Dreyer D, Jaeger F, et al. Complete characterization of the human IGF-I nucleotide sequence isolated from a newly constructed adult liver cDNA library. FEBS Lett 1986;196:108-112.
35. Kozak M. Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNA's. Nucleic Acids Res 1984;12:857-872.
36. Norstedt G, Moller C. Growth hormone induction of insulin-like growth factor I messenger RNA in primary cultures of rat liver cells. J Endocrinol 1987;115:135-139.
37. D'Ercole AJ, Stiles AD, Underwood LE. Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc Natl Acad Sci U S A 1984;81:935-939.
38. Elford PR, Lamberts SWJ. Contrasting modulation by transforming growth factor-B-1 of insulin-like growth factor-1 production in osteoblasts and chondrocytes. Endocrinology 1990;127: 1635-1639.
39. Tsukazaki T, Usa T, Matsumoto T, et al. Effect of transforming growth factor-B on the insulin-like growth factor-1 autocrine/ paracrine axis in cultured rat articular chondrocytes. Exp Cell Res 1994;215:9-16.